Additive manufacturing (AM) is making a profound impact on our ability to realize complex metamaterials and structures, but fully realizing the manufacturing freedom afforded by AM requires some significant advances in engineering design methods and tools. For some additive manufacturing applications, simulation-based design tools may be required to explore a hierarchy of features, ranging in size from microns to meters. At the same time, these tools need to provide real-time feedback on the constraints and process-structure-property relationships relevant to specific AM technologies, and this Design-for-AM feedback is needed during the design process, rather than at the end. To address these challenges, a design exploration approach has been established for creating inverse maps of promising regions of a hierarchical structural/material design space. The approach utilizes machine learning classifiers for identifying sets of promising solutions to a materials design problem, combined with statistical characterization of geometric features and material properties to ensure that the designs are robustly manufacturable. The capabilities of the approach are demonstrated by applying it to the hierarchical design of negative stiffness metamaterials for energy absorption applicationsAdditive manufacturing (AM) is making a profound impact on our ability to realize complex metamaterials and structures, but fully realizing the manufacturing freedom afforded by AM requires some significant advances in engineering design methods and tools. For some additive manufacturing applications, simulation-based design tools may be required to explore a hierarchy of features, ranging in size from microns to meters. At the same time, these tools need to provide real-time feedback on the constraints and process-structure-property relationships relevant to specific AM technologies, and this Design-for-AM feedback is needed during the design process, rather than at the end. To address these challenges, a design exploration approach has been established for creating inverse maps of promising regions of a hierarchical structural/material design space. The approach utilizes machine learning classifiers for identifying sets of promising solutions to a materials design problem, combined with statistical char...