We show that long wave-short wave resonance can be achieved in a second-order nonlinear negative refractive index medium when the short wave lies on the negative index branch. With the medium exhibiting a second-order nonlinear susceptibility, a number of nonlinear phenomena such as solitary waves, paired solitons, and periodic wave trains are possible or enhanced through the cascaded second-order effect. Potential applications include the generation of terahertz waves from optical pulses.