Negative Preferences Research Articles

Exploring the Insecticidal and Repellent Activity of Garlic Essential Oil against Sitophilus oryzae (L.) Infestation in Stored Maize

The potential of garlic essential oil for its insecticidal and repellent properties against the rice weevil, Sitophilus oryzae was investigated through various bioassays. The results of the contact toxicity assay showed that the mortality rates were dependent on the concentration of the garlic essential oil, and its effectiveness increased with time. This was evident from the decreasing median lethal doses (LC50) over the course of the study, ranging from 7.13 µl/ 20g of seeds (1 DAT) to 3.40 µl / 20g of seeds (5 DAT). The highest repellency rate of 88.89 per cent was achieved with a concentration of 6µl over a 4-hour period. This finding was further supported by the negative preference indices, which ranged from -1.0 to -0.1. With regard to fumigant toxicity assay, the LC50 values decreased as the study progressed, ranging from 4.72 µl /96cm3 (1 DAT) to 1.70 µl/96cm3 (5 DAT). Thus, garlic essential oil can be considered as a potent botanica compound on account of its contact, repellent and fumigant toxicity properties against Sitophilus oryzae. The results of this study underscore the potential of garlic essential oil as a promising compound for the management of S. oryzae.

Collective negative shocks and preferences for redistribution: Evidence from the COVID-19 crisis in Germany

Using new data from a three-wave panel survey administered in Germany between May 2020 and May 2021, this paper studies the impact of a negative shock affecting all strata of the population, such as the development of COVID-19, on preferences for redistribution. Exploiting the plausibly exogenous change in the severity of the infection rate at the county level, we show that, contrary to some theoretical expectations, the worse the crisis, the less our respondents expressed support for redistribution. We provide further evidence that this is not driven by a decrease in inequality aversion but might be driven by the individuals’ level of trust.

Discovering Aethina tumida responses to attractant and repellent molecules: A potential basis for future management strategies

Small hive beetle (Aethina tumida) management has been highly dependent upon chemical and mechanical control over the past two decades; however, many of these methods have not been consistently effective or safe for European honey bee (Apis mellifera) colonies. Here we explore the behavioral and physiological effects of the attractants isopentyl acetate and pollen patty upon A. tumida adults, and also investigate the mixture of attractants with repellent compounds, which were previously untested against A. tumida. Electroantennograms established sensitivity of A. tumida antennae to both attractants and all repellents with the exception of DEET, with antennae displaying greatest sensitivity to the repellent pyrrolidine. A walking-response olfactometer, designed specifically for A. tumida, was used for all behavioral experiments. It was found that both pollen patty and isopentyl acetate were attractive to A. tumida adults; conversely, mixes of attractants and repellent volatiles led to less attraction or avoidance of what was previously a significantly attractive source. Of all repellents tested, pyrrolidine was found to be the most repelling molecule, with significant avoidance of the attractive source at a 10 mg treatment of pyrrolidine. The results of this study indicate that, at the behavioral level, the repellent compounds pyrrolidine and 1,4-dimethylpiperazine resulted in a negative preference index indicating a repellent behavioral response. By strategically implementing a repellent source in an apiary environment, A. tumida adults could be deterred from entering and invading hives.

University College Students’ Experiences with Online Teaching One Year after COVID-19 Lockdown in Spring 2020

The aim of this study was to explore university college students’ experiences with online teaching one year after the lockdown in spring 2021.With quantitative cluster analysis, we have identified a “learning gradient” among students, showing that cluster 1 students have the most positive preferences towards online teaching and the highest degree of self-regulation and learning outcome, cluster 2 students are mixed (both positive and negative experiences), and cluster 3 students have the most negative preferences and the lowest self-regulation and learning outcome. In this study, we used 5 focus group interviews with 29 students based on their preferences towards online teaching to discuss and reflect on their own study planning, the shift in the learning environment, their perceived learning outcome, and positive and negative experiences from online teaching. The results from this study have shown that students’ self-regulated learning strategies during online teaching environment are important for their learning outcome. Thus, we demonstrate the disjunction between students’ learning outcome and the classroom as a fixed place for learning.

A discourse analysis of suicide ideation assessment among first year health professional students enrolled in a communications course

Background: Suicide risk assessments require a complex set of skills around a sensitive matter which can be difficult for providers. Aim: Research investigating communication techniques and the language choices used to assess for suicide ideation is limited. Methods: We analyzed 121 video-recorded and transcribed final exams from a communication skills course for first year health professional students to identify patterns and variation in the language choices made to assess for suicidal ideation in standardized patients exhibiting symptoms of depression. Results: We found that 66 of the 121 (55%) interviews included a suicide assessment. We noted key patterns and variation around when the assessments took place (while exploring depressive symptoms or as a topic shift), how they were prefaced (with ubiquity statements, normalization statements, or expressions of care and concern), and how the question itself was structured (with a negative preference structure, in a non-polar format, or ambiguously). Conclusions: Assessing for suicide is a delicate task for both patients and providers, both of whom may be reluctant to engage around the topic. Utilizing normalization statements as well as statements of care and concern is a good approach to assess suicide idation while exploring depressive symptoms.

Prosthesis preferences for those with upper limb loss: Discrete choice study of PULLTY® for use in regulatory decisions.

The patient's voice in shared decision-making has progressed from physician's office to regulatory decision-making for medical devices with FDA's Patient Preference Initiative. A discrete-choice preference measure for upper limb prosthetic devices was developed to investigate patient's risk/benefit preference choices for regulatory decision making. Rapid ethnographic procedures were used to design a discrete-choice measure describing risk and benefits of osseointegration with myoelectric control and test in a pilot preference study in adults with upper limb loss. Primary outcome is utility of each choice based conjoint (CBC) attribute using mixed-effects regression. Utilities with and without video, and between genders were compared. Strongest negative preference was for avoiding infection risk (B = -1.77, p < 0.001) and chance of daily pain (B = -1.22, p, 0.001). Strongest positive preference was for attaining complete independence when cooking dinner (B = 1.62, p < 0.001) and smooth grip patterns at all levels (B = 1.62, B = 1.28, B = 1.26, p < 0.001). Trade-offs showed a 1% increase in risk of serious/treatable infection resulted in a 1.77 decrease in relative preference. There were gender differences, and where video was used, preferences were stronger. Strongest preferences were for attributes of functionality and independence versus connectedness and sensation but showed willingness to make risk-benefit trade-offs. Findings provide valuable information for regulatory benefit-risk decisions for prosthetic device innovations. This study is not a clinical trial reporting results of a health care intervention so is not registered.

Yogurt added with beetroot extract: physicochemical parameters, biological activities and sensory evaluation by check‐all‐that‐apply method

SummaryBeetroot is a vegetable rich in betalains, which contains colouring and functional properties that can be beneficial in processing dairy products. In order to combine the benefits of yogurt and beetroot, the objective was to elaborate whole yogurts added with beetroot syrup in the following concentrations: 0% (T1), 13% (T2), 17% (T3) and 20% (T4), and to determine its physicochemical characteristics, biological activities and sensory attributes by the Check‐All‐That‐Apply (CATA) method and acceptance by hedonic scale, compared to the control yogurt with the addition of 5% w/w sucrose (T1). The beet syrup had a high content of betacyanins and betaxanthins (491.01 ± 1.67 mg.L−1 and 226.15 ± 0.26 mg. L−1 respectively). There was a progressive increase in the inhibition of ACE, α‐glucosidase and α‐amylase and antioxidant activity as the syrup content increased in the formulations (P &lt; 0.05). The sensory attributes ‘acid aroma’, ‘earthy flavour’, ‘bitter taste’ and ‘fluid texture’ were considered negative preference drivers for T2 and T4, while T3 yogurt was the most appreciated by consumers. Despite showing colour changes during storage, adding beet syrup promoted a naturally attractive colour to the yogurts. The results suggest that the addition of beetroot syrup in yogurts, in addition to being an alternative to using artificial colouring in the industry, can provide health benefits to consumers by forming bioactive compounds.

Extended PROMETHEE approach with 2‐tuple linguistic m‐polar fuzzy sets for selection of elliptical cardio machine

AbstractThe Preference Ranking Organization Method for Enrichment of Evaluations (PROMETHEE) is an outranking series of multi‐attribute decision making used to assess a finite collection of alternatives based on conflicting criteria. One of its significant benefits is its adjustability in response to a set of acceptable preference functions that may quantify the differences between alternatives conditional on the kind and structure of the criteria. This article offers the novel approach of the PROMETHEE method, named the 2TLmF PROMETHEE method, which combines the multi‐polarity with linguistic information of decision problems. The customary procedure of the offered technique begins with the normalized weights of the attributes assigned by decision‐makers. After that, Gaussian and the usual preference functions are utilized to determine the preferences of the alternatives. The ultimate choice is based on the alternative's positive and negative outranking flow. The positive outranking demonstrates how one alternative outranks all other options, while the negative preference flow implies an alternative is superior to all other options. There are several modifications to the PROMETHEE approach, two of which are discussed in this article. The first is PROMETHEE I, which uses positive and negative preference flows to generate a partial ranking. Secondly, PROMETHEE II gives a comprehensive rating list based on the net flow, representing the balance of positive and negative preference flows. Further, a comprehensive flowchart is used to show the entire picture of the proposed methodology. As an application, a real‐life situation related to selecting an elliptical machine for a home gym is chosen to illustrate the transparency and reliability of the presented work. Finally, a comparative study is carried out to illustrate the strength and applicability of the proposed method.

Selection bias mitigation in recommender system using uninteresting items based on temporal visibility

Most collaborative filtering recommendation algorithms rely too much on the user's historical rating data. However, selection bias is common in explicit feedback data, which makes the learning of user preferences face more challenges. We verify the influence of selection bias on topN recommendation, and propose a data filling strategy using uninteresting items based on temporal visibility to alleviate the selection bias in the data. Specifically, our method includes a weighted matrix factorization model to learn users' pre-use preferences for unrated items. According to the experience of items that users have seen but not interacted show negative preferences, we combine user activity, item popularity and temporal rating information to carry out non-uniform weighting to evaluate the confidence of unrated items as a negative example. Then the items with low pre-use preferences are taken as uninteresting items and filled in a low value to restore the user's real rating distribution. Experiments on two real world datasets show that our algorithm can effectively alleviate the selection bias and improve the recommendation accuracy.

Normed Negative Voting to Depolarize Politics

Are the voter preferences clearly heard in a plurality voting system? Alternate voting schemes wherein the voters rank their choices instead of just voting for their first preference certainly capture the voter preferences in a richer format, but they do not explicitly capture the negative preferences. Here we propose a voting scheme that blends negative voting within a cumulative voting system. In this scheme, we can simultaneously decipher the popularity as well as the polarity of each candidate contesting in the election, giving us a two dimensional view of the candidates. An incentive structure can be built into voting system whereby we can penalize the candidates for their polarity and discourage polarizing campaign rhetorics. Theoretically, this could help depolarize the heated political environment and level the playing field for third party candidates.

Teachers’ preferences for online professional development: Evidence from a discrete choice experiment

This paper reports on teachers' preferences for online professional development programmes in Indonesia. Relying on data from 330 university English teachers, the results of our discrete choice experiment suggest a significant positive preference for synchronous interaction but a negative preference for costly programmes, programmes offering no certificates of participation or completion, conducted over a longer period and using digital reading materials on teachers' preferences. Subgroup analyses also show that age, gender and experience with online professional development programmes influence teachers’ preferences. Based on these findings, implications for the design of online professional development and gaps for future research are discussed.

Patient Preferences for Strategies to Improve Tuberculosis Diagnostic Services in Zambia

Delayed engagement in tuberculosis (TB) services is associated with ongoing transmission and poor clinical outcomes. To assess whether patients with TB have differential preferences for strategies to improve the public health reach of TB diagnostic services. A cross-sectional study was undertaken in which a discrete choice experiment (DCE) was administered between September 18, 2019, and January 17, 2020, to 401 adults (>18 years of age) with microbiologically confirmed TB in Lusaka, Zambia. The DCE had 7 attributes with 2 to 3 levels per attribute related to TB service enhancements. Latent class analysis was used to identify segments of participants with unique preferences. Multiscenario simulations were used to estimate shares of preferences for different TB service improvement strategies. The main outcomes were patient preference archetypes and estimated shares of preferences for different strategies to improve TB diagnostic services. Collected data were analyzed between January 3, 2022, to July 2, 2022. Among 326 adults with TB (median [IQR] age, 34 [27-42] years; 217 [66.8%] male; 158 [48.8%] HIV positive), 3 groups with distinct preferences for TB service improvements were identified. Group 1 (192 participants [58.9%]) preferred a facility that offered same-day TB test results, shorter wait times, and financial incentives for testing. Group 2 (83 participants [25.4%]) preferred a facility that provided same-day TB results, had greater privacy, and was closer to home. Group 3 (51 participants [15.6%]) had no strong preferences for service improvements and had negative preferences for receiving telephone-based TB test results. Groups 1 and 2 were more likely to report at least a 4-week delay in seeking health care for their current TB episode compared with group 3 (29 [51.3%] in group 1, 95 [35.8%] in group 2, and 10 [19.6%] in group 3; P < .001). Strategies to improve TB diagnostic services most preferred by all participants were same-day TB test results alone (shares of preference, 69.9%) and combined with a small financial testing incentive (shares of preference, 79.3%), shortened wait times (shares of preference, 76.1%), or greater privacy (shares of preference, 75.0%). However, the most preferred service improvement strategies differed substantially by group. In this study, patients with TB had heterogenous preferences for TB diagnostic service improvements associated with differential health care-seeking behavior. Tailored strategies that incorporate features most valued by persons with undiagnosed TB, including same-day results, financial incentives, and greater privacy, may optimize reach by overcoming key barriers to timely TB care engagement.

Paying for the Greater Good?-What Information Matters for Beijing Consumers' Willingness to Pay for Plant-Based Meat?

Promoting the transition from animal meat to plant-based food consumption has significant benefits for public health and environmental sustainability. This study, involving 526 consumers from Beijing, China, explores how food attributes and information may affect consumers’ food choices concerning plant-based meat products. A discrete choice experiment was conducted using burgers with five attributes (meat patties, flavor, sodium content, energy, and price) as the focal product. Separate messages on nutrition, food safety, and the environmental issues related to plant-based meat consumption were also randomly provided to consumers to help examine the role of information. Our findings suggest that Beijing consumers’ awareness of plant-based meat is relatively low at present, and they show a negative preference toward plant-based meat consumption relative to that of conventional meat. However, consumers’ willingness to pay for plant-based meat significantly increased after nutrition information was provided, but it was not responsive to the provision of food safety or environmental information. These findings suggest that to promote plant-based meat consumption, information closely related to consumers’ personal interests rather the “greater good” should be provided, at least in the context of Beijing, China.

Large carnivores and naturalness affect forest recreational value

Recreation is a crucial contribution of nature to people, relevant for forest ecosystems. Large carnivores (LCs) are important components of forests, however, their contribution to forest recreational value has not yet been evaluated. Given the current expansion of LC populations, the ongoing forest conservation debate, and the increasing use of nature for recreational purposes, this is a timely study. We used discrete choice experiments and willingness-to-travel to determine people’ preferences for both forest structural characteristics and presence of four LC species in Poland (N = 1097 respondents) and Norway (N = 1005). In both countries, two-thirds of the respondents (termed ‘wildness-positive’) perceived LCs as contributing positively to forest recreational value and preferred to visit old forests with trees of different species and ages and presence of dead wood (i.e. natural forests). Respondents with negative preferences towards LCs preferred more intensively managed forest (‘wildness-negative’); their preferences were stronger than in wildness-positive respondents and in Norway. Preferences towards wild nature were highly polarized and there were hardly neutral people. Our results showed a strong link between preferences for LC presence and forest structure, and reflected the dualism of human-nature relationships. This study highlights the need to consider the contribution of forests and LCs to human recreation services in ecosystem management policies.

Patient Preference for Self-Injection Devices in Rheumatoid Arthritis: A Discrete Choice Experiment in China.

ObjectiveRheumatoid arthritis (RA) is increasingly treated with biologics, which is commonly administered by injection devices. The aim of this study is to evaluate patients’ preferences for self-injection devices in RA, and to elicit their willingness to pay (WTP) for injector devices in China.MethodsRA patients were recruited from Beijing, Shanghai, Guangzhou, Chengdu, Wuhan and Xi’an in China. A discrete choice experiment (DCE) was employed to elicit patient preferences. Patients were presented with 15 choice sets that consisted of seven attributes, which were developed based on literature review and further validated by physicians. The seven attributes were as follows: operation steps, injection pain, feedback indication, needle visibility, needle protection, size and out-of-pocket costs. A mixed logit model was used to analyze the relative importance of seven attributes and to calculate the WTP for a changed attribute level.ResultsAnalyses included 114 adults with RA (mean age of 44.6 years old). When choosing the injection device, all attributes had significant influence. Among nonmonetary attributes, very slight injection pain was the most preferred for patients, followed by auto-injection method, thicker size, hidden needle, with needle protection and multiple feedback indication. Patients had a negative preference for increasing out-of-pocket costs. Patients were willing to pay CNY 45.26 for improving slight injection pain to very slight injection pain, CNY 13.26 for the auto-injection method, CNY 12.22 for the thicker size, CNY 10.06 for the hidden needle, CNY 9.82 for needle protection, and CNY 9.70 for multiple feedback indicators.ConclusionThe results suggested that injection pain was the most important attribute for RA patients. Meanwhile, all other enhanced attributes of self-injection devices also significantly influence patients’ selection on injection devices. Findings suggested that there is significant potential value in developing self-injection devices that could further help improve treatment adherence and promote patient-centered care in autoimmune diseases.

Public preferences for safe consumption sites for opioid use: A discrete choice experiment

BackgroundSafe consumption sites provide people who use drugs with medical supervision and sterile paraphernalia for drug use. Although the presence of sites in neighborhoods can be controversial, few studies have assessed the preferences of individuals for attributes of safe consumption sites. MethodsA discrete choice experiment was conducted to assess public preferences for safe consumption sites. Logit and mixed logit models were used to analyze data. Participants were recruited from Conjointly.com using a sample of the general population in Canada. The sample included adults only, was split approximately evenly by gender, and reflects census data for household income and geographic area. Attributes included: cost of the site to the healthcare system; effectiveness of the site in reducing overdose death; financial compensation to residents if a site opens in their neighborhood; if the site is located in the respondent’s neighborhood; and if the site reduces improperly discarded needles. ResultsThe sample consisted of 203 respondents. Respondents had negative preferences for sites that increased cost to the healthcare system. Conversely, they had positive preferences for sites that would reduce fatal overdoses, that could reduce improperly discarded needles, and sites that provided compensation to those impacted by the establishment of sites. ConclusionsFindings suggest that there exist a set of attributes that influence respondents’ preferences for safe consumption sites. By considering these attributes when designing sites and developing messaging for sites, decision-makers may develop sites that are potentially less controversial.

Dysfunction of Emotion Regulation in Mild Cognitive Impairment Individuals Combined With Depressive Disorder: A Neural Mechanism Study.

Depression increases the risk of progression from mild cognitive impairment (MCI) to dementia, where impaired emotion regulation is a core symptom of depression. However, the neural mechanisms underlying the decreased emotion regulation in individuals with MCI combined with depressive symptoms are not precise. We assessed the behavioral performance by emotion regulation tasks and recorded event-related electroencephalography (EEG) signals related to emotion regulation tasks simultaneously. EEG analysis, including event-related potential (ERP), event-related spectral perturbation (ERSP), functional connectivity and graph theory, was used to compare the difference between MCI individuals and MCI depressed individuals in behavioral performance, the late positive potential (LPP) amplitudes, neural oscillations and brain networks during the processing of emotional stimuli. We found that MCI depressed individuals have negative preferences and are prone to allocate more attentional resources to negative stimuli. Results suggested that theta and alpha oscillations activity is increased, and gamma oscillations activity is decreased during negative stimulus processing in MCI depressed individuals, thus indicating that the decreased emotion regulation in MCI depressed individuals may be associated with enhanced low-frequency and decreased high-frequency oscillations activity. Functional connectivity analysis revealed a decrease in functional connectivity in the left cerebral hemisphere of the alpha band and an increase in functional connectivity in the right cerebral hemisphere of the alpha band in MCI depressed individuals. Graph theory analysis suggested that global network metrics, including clustering coefficients and disassortative, decreased, while nodal and modular network metrics regarding local nodal efficiency, degree centrality, and betweenness centrality were significantly increased in the frontal lobe and decreased in the parieto-occipital lobe, which was observed in the alpha band, further suggesting that abnormal alpha band network connectivity may be a potential marker of depressive symptoms. Correlational analyses showed that depressive symptoms were closely related to emotion regulation, power oscillations and functional connectivity. In conclusion, the dominant processing of negative stimuli, the increased low-frequency oscillations activity and decreased high-frequency activity, so as the decrease in top-down information processing in the frontal parieto-occipital lobe, results in the abnormality of alpha-band network connectivity. It is suggested that these factors, in turn, contribute to the declined ability of MCI depressed individuals in emotion regulation.

Effectiveness evaluation method of constellation satellite communication system with acceptable consistency and consensus under probability hesitant intuitionistic fuzzy preference relationship

System effectiveness evaluation is an essential part of constellation satellite communication system research, with applications in project verification and optimization as well as tactical and technical measurement argumentation. This paper presents a systematic and comprehensive effectiveness evaluation method for a constellation satellite communication system under a probabilistic hesitant intuitionistic fuzzy preference relationship (PHIFPR), aiming to address the fuzziness and uncertainty in effectiveness evaluation. First, a proposed definition of PHIFPR describes the hesitancy of evaluators, provides hesitancy distribution information, and depicts the worst negative information and risk preferences in effectiveness evaluation. Then, we deduce the approximate consistency index of PHIFPR and establish a mathematical programming model to increase individual consistency when the approximate consistency index does not reach a predetermined level. In the sequel, a proposed group consensus index uses the PHIFPR-based Hausdorff distance to measure the closeness between evaluators’ judgments. Afterwards, a consistency and consensus improvement model is designed to retain the original opinions of evaluators to make the consistency and consensus of PHIFPRs acceptable. Moreover, a goal programming model is established to gain the approximate priority weights of schemes regarding the approximate consistency condition of a PHIFPR as a fuzzy constraint. Finally, an experimental example is offered to highlight the practicability and feasibility of the proposed method, and some comparative analyses with other methods offer insights into the designed method.

Dietary discrimination using a dual-choice self-feeding system in seabream (Sparus aurata)

Self-feeding systems have been extensively used to study animal behaviour and food preferences in vertebrates. In this study, we used a dual-choice self-feeding system to explore feeding behaviour and dietary discrimination based on organoleptic cues. Experimental tanks were provided with 2 self-feeders activated by string sensors and connected to a computer system. In the first experiment (E1) [6 tanks, 10 animals/tank, body weight (BW) 266 g ± 19.4 g], both feeders delivered the same control standard diet to evaluate the potential preference for one feeder. E1 had 3 phases: 1st, animals were allowed to demand from both feeders; 2nd, from only one feeder and 3rd from both feeders again. The second experiment (E2) (11 tanks, 15 animals/tank, BW range 25–50 g) examined whether seabream can discriminate between 3 isoenergetic diets: the control diet; a positive/palatable diet containing high levels of fish, squid and krill meal; and a negative diet in which 1.5% quinine hydrochloride was added to the control diet. E2 had 3 phases: 1st acclimation with control diet; 2nd dual-choice; 3rd dual-choice with reversal of feeders. The third experiment (E3) (8 tanks, 10 animals/tank, BW range 25-50 g) was performed using a single self-feeder per tank, with each tank being fed either control or quinine diet, to corroborate the aversive response to quinine in the absence of dietary choice. E1 demonstrated that animals demanded significantly less when only one feeder/sensor was available. E2 shows that seabream can easily discriminate a bitter compound (quinine) in the diet, showing negative preference (P < 0.05) in both phases, 2nd and 3rd. When no choice was available (E3), seabream equally demanded control or quinine diet, presumably driven by its energy requirements. However, the presence of the bitter substance increased feed refusals, 14.3% rejection of demanded feed in quinine diet, versus 2.6% in control diet, indicating a role of sensory systems in assessing food quality. A positive conditioning with a palatable diet was not effective and no positive choices were measured over a basal diet, although results were possibly influenced by the previous familiarization with the basal diet and by the experimental conditions (fast growing juveniles at high temperature). This poor dietary selection during active feeding periods could partly explain the easy adaptation of this species to substitution diets. Finally, results suggest that food intake is conditioned by agonistic behaviour in an age-dependent manner. The information will be useful for diet and feeding strategy design in seabream.

Time and lexicographic preferences in the valuation of EQ-5D-Y with time trade-off methodology

In the valuation of EQ-5D-Y-3L, adult respondents are asked to complete composite time trade-off (cTTO) tasks for a 10-year-old child. Earlier work has shown that cTTO utilities elicited in such a child perspective are generally higher than when adults take their own perspective. We explore how differences in time preference in child and adult perspectives could explain this effect. Furthermore, as cTTO valuation in a child perspective involves explicit consideration of immediate death for a child, we also consider how cTTO utilities could be affected by decision-makers lexicographically avoiding death in children. We report the results of an experiment in which 219 respondents valued 5 health states in both adult and child perspectives with either a standard cTTO or a lead-time TTO only approach, in which immediate death is less focal. Time preferences were measured in both perspectives. Our results suggest that utilities were lower when lead-time TTO, rather than cTTO, was used. We find large heterogeneity in time preference in both perspectives, with predominantly negative time preference. The influence of time preferences on utilities, however, was small, and correcting for time preferences did not reduce differences between utilities elicited in both perspectives. Surprisingly, we found more evidence for differences in utilities between adult and child perspectives when lead-time TTO was used. Overall, these results suggest that time and lexicographic preferences affect time trade-off valuation in child and adult perspectives, but are not the explanation for differences between these perspectives. We discuss the implications of our findings for EQ-5D-Y-3L valuation.