Non-significant Negative Correlation Research Articles

Study of Seasonal Incidence of Rice Earhead Bug (Coreidae: Hemiptera)

This study investigates the relationship between climatic factors and the population dynamics of the rice earhead bug (Leptocorisa acuta) in Balaghat district of Madhya Pradesh. Through correlational analysis, we examined the associations between rainfall, rainy days, morning relative humidity (RH), evening RH, evening vapour pressure, wind velocity, maximum temperature, morning vapour pressure, evaporation, sunshine, and the prevalence of rice earhead bugs. Results indicate a negative correlation between rice earhead bug population and both rainfall and rainy days, suggesting a potential suppression effect of increased precipitation on bug abundance. Morning RH, evening RH, evening vapour pressure, and wind velocity showed non-significant negative correlations with bug population, indicating that these factors may have limited influence on bug dynamics in our study area. Conversely, a positive non-significant correlation was observed between rice earhead bug population and maximum temperature, morning vapour pressure, evaporation, and sunshine. This implies that higher temperatures and increased solar radiation may have a subtle positive effect on bug abundance, although further investigation is warranted to elucidate the underlying mechanisms. Overall, our findings shed light on the complex interplay between climatic factors and rice earhead bug dynamics, highlighting the importance of considering multiple variables in pest management strategies for rice cultivation.

Detecting Potassium Rebound in a Prevalent Hemodialysis Population

Abstract Background One of the fundamental goals of hemo dialysis (HD) prescription is to maintain serum potassium (K) levels within a narrow normal range during both the intradialytic and interdialytic intervals. Considering the extraordinarily high rate of cardiovascular mortality in HD population, clinicians are obligated to explore whether factors related to dialytic K removal can be modified to improve clinical outcomes. Aim of the Work The aim of the study was to detect potassium rebound after HD sessions in patients on maintenance HD Patients and Methods This was a prospective cohort study that was held in Hemodialysis units in Nephrology department - Ain Shams University Hospital and Sheikh Zayed Specialized Hospital for 3 months. The study included 60 male and female ESRD patients on maintenance HD, in which prevalent HD patients on maintenance HD 3 times/week. Results We found that that there were significant positive correlations between K levels before the sessions, immediately after the sessions and after 6 hours of the sessions. While there was significant negative correlations between K levels immediately after HD sessions and Hb levels and urea levels. There was also a highly significant negative correlation between K levels before the sessions and time of session (in hours). While there were highly significant negative correlations between K levels immediately after the sessions, after 6 hours of sessions and time of session (in hours). There was non-significant negative correlations between all K levels (before HD sessions, immediately after the sessions and 6 hours after the sessions) and frequency of sessions (per week), with p value 0.388, 0.299 and 0.086 respectively. Also, it showed non-significant negative correlations between all K levels (before HD sessions, immediately after the sessions and 6 hours after the sessions) and frequency of sessions (per month), with p value 0.086, 0.089 and 0.083 respectively. Our results showed a significant positive relation between the number of K raising antihypertensive drugs used by the patients and K levels before HD sessions. Conclusion Patients with end-stage renal disease (ESRD) on maintenance dialysis have a high risk of developing hyperkalemia, generally defined as serum potassium (K+) concentrations of > 5.0 mmol/l, particularly those undergoing maintenance hemodialysis. Currently, the key approaches to the management of hyperkalemia in patients with ESRD are dialysis, dietary K+ restriction, and avoidance of medications that increase hyperkalemia risk. Management of these modifiable factors plays a crucial role in preventing hyperkalemia in patients undergoing dialysis. The availability of new oral K+-binders may potentially reduce the need for a highly restricted diet in patients with ESRD, and reduce the risk of potentially life-threatening hyperkalemia and the cardiovascular complications associated with rapid shifts in serum K+ concentrations that can occur with HD.

Unraveling Genetic Variability, Correlation and Path Analysis for Yield and Its Components in Barley (Hordeum vulgare L.)

The current study aimed to assess the genetic variability of yield and yield-related traits while examining the direct and indirect effects of trait interactions. Conducted at a research farm in Chaudhary Charan Singh University, Meerut, Uttar Pradesh, India, the experiment involved fourteen parents and their BC1F1 crosses, analyzed using a randomized block design (RBD). Significant differences were observed among the varieties for most traits, indicating a broad range of mean values and diversity. Both phenotypic and genotypic coefficients of variance (PCV and GCV) were generally low, with biological yield showing the highest values (26.57 for GCV and 40.48 for PCV). PCV values were slightly higher than GCV values. Traits such as seed per spike, biological yield, flag leaf breadth, days of heading, and days of maturity exhibited relatively high heritability. Notably, grain yield showed high heritability and genetic progress, making it a favourable selection indicator. Several traits, including days of anthesis, days of maturity, and spike length, demonstrated significant positive correlations with yield while also showing significant negative correlations with grain filling period and biological yield. Conversely, these traits showed highly non-significant positive correlations with harvest index, plant height, thousand seeds weight, and chlorophyll content and highly non-significant negative correlations with tiller number and seeds per spike.

Electrocardiographic Patterns and Ejection Fraction in Patients with Nonischemic Dilated Cardiomyopathy: A Cross-sectional Retrospective Study

Background:: The relationship between ECG changes in dilated nonischemic cardiomyopathy and ejection fraction (EF) is complex and poorly understood. Thus, this study aimed to identify the most common patterns of ECG associated with dilated nonischemic cardiomyopathy and their relationship to EF. Methods:: A retrospective cross-sectional study was conducted between 2019 and 2022, including 100 consecutive patients with nonischemic dilated cardiomyopathy. ECG data were rate, axis, left (LBBB) and right bundle branch block (RBBB), first-degree heart block, premature ventricular contractions, depth of S wave in leads V1 and V2, length of R wave in leads V2 and V6, the ratio of R/S in the lead V4, left ventricular hypertrophy (LVH), maximum R wave length in leads I, II, and III, poor R wave progression, ST-segment elevation, and T wave inversion. Results:: The most common ECG pattern associated with cardiomyopathy was T-wave inversion (47%). The EF was 23.9± 8.87% in patients with LBBB and 25.5± 8.07% in patients without LBBB (P= 0.361). In patients with T-wave inversion, the EF was 23.4± 8.21%, and it was 26.28± 8.35% in patients without T-wave inversion (P= 0.086). In patients with LVH, the EF was 23.89± 7.84%, and it was 25.5± 8.66% in patients without LVH (P= 0.354). A negative nonsignificant correlation existed between SV1, SV2, RV2, RV6, R/S V4, and maximum R in I, II, III, and EF. Conclusions:: The study showed that T-wave inversion was the most common pattern associated with dilated nonischemic cardiomyopathy. The study provided insight into the negative correlation between EF and SV1, SV2, RV2, RV6, R/S V4, and maximum R in I, II, and III, although it did not reach a significant level.

Item analysis: the impact of distractor efficiency on the difficulty index and discrimination power of multiple-choice items

BackgroundDistractor efficiency (DE) of multiple-choice questions (MCQs) responses is a component of the psychometric analysis used by the examiners to evaluate the distractors’ credibility and functionality. This study was conducted to evaluate the impact of the DE on the difficulty and discrimination indices.MethodsThis cross-sectional study was conducted from April to June 2023. It utilizes the final exam of the Principles of Diseases Course with 45 s-year students. The exam consisted of 60 type A MCQs. Item analysis (IA) was generated to evaluate KR20, difficulty index (DIF), discrimination index (DIS), and distractor efficiency (DE). DIF was calculated as the percentage of examinees who scored the item correctly. DIS is an item’s ability to discriminate between higher and lower 27% of examinees. For DE, any distractor selected by less than 5% is considered nonfunctional, and items were classified according to the non-functional distractors. The correlation and significance of variance between DIF, DI, and DE were evaluated.ResultsThe total number of examinees was 45. The KR-20 of the exam was 0.91. The mean (M), and standard deviation (SD) of the DIF of the exam was 37.5(19.1), and the majority (69.5%) were of acceptable difficulty. The M (SD) of the DIS was 0.46 (0.22), which is excellent. Most items were excellent in discrimination (69.5%), only two were not discriminating (13.6%), and the rest were of acceptable power (16.9%). Items with excellent and good efficiency represent 37.3% each, while only 3.4% were of poor efficiency. The correlation between DE and DIF (p = 0.000, r= -0.548) indicates that items with efficient distractors (low number of NFD) are associated with those having a low difficulty index (difficult items) and vice versa. The correlation between DE and DIS is significantly negative (P = 0.0476, r=-0.259). In such a correlation, items with efficient distractors are associated with low-discriminating items.ConclusionsThere is a significant moderate negative correlation between DE and DIF (P = 0.00, r = -0.548) and a significant weak negative correlation between DE and DIS (P = 0.0476, r = -0.259). DIF has a non-significant negative correlation with DIS (P = 0.7124, r = -0.0492). DE impacts both DIF and DIS. Items with efficient distractors (low number of NFD) are associated with those having a low difficulty index (difficult items) and discriminating items. Improving the quality of DE will decrease the number of NFDs and result in items with acceptable levels of difficulty index and discrimination power.

Evaluation of elite spring wheat genotypes for grain yield and other agronomic attributes in hills of Sudurpaschim Province, Nepal

Selection and release of high yielding and disease resistant varieties is the cost effective and ecologically sound approach for increasing the production and productivity of agricultural crop in Nepal. Twenty-two advanced bread wheat (Triticum aestivum L.) genotypes including commercial check variety "Sorgadwari", newly released check variety "Khumal Shakti" and Local Check variety " Jhadde" were evaluated under irrigated conditions at Gokuleshwor Agriculture and Animal Science College (GAASC), Baitadi, Nepal during 2022/2023. This study was carried out for the identification of high yielding genotypes under irrigated condition in western hills. The experiment was conducted in Alpha lattice design with two replications. The highly significant difference (p<0.01) among the genotypes was found for most of the traits viz., days to heading, days to anthesis, days to maturity, plant height, spikes per square meter, number of grains per spike, grain weight per spike, flag leaf area, thousand kernel weight, biomass yield and grain yield and non-significant difference for spike length. The mean grain yield ranged from 1908 to 4146 kg/ha with grand mean of 2766 kg/ha. The highest grain yield was produced by genotype NL 1474 (4146 kg/ha) which was followed by NL 1475 (3994 kg/ha), NL1597 (3536 kg/ha) and NL 1590 (3070 kg/ha). The check variety Sorgadwari and Khumal Shakti produced 3480 and 3070 kg/ha respectively while the local check variety Jhadde produced 2655 kg/ha. Similarly, highest TKW was produced by NL 1487 (68.5 g) followed by BL 5148 (67.2 g) and WK 3730 (66.3 g). The correlation analysis revealed that grain yield showed highly significant positive correlation with biomass yield (0.90**) and number of grains per spike (0.6**), spikes per square meter (0.7**), plant height (0.5**) and non-significant positive correlation with spike length (0.21) and grain weight per spike (0.1) and non-significant negative correlation with days to heading (-0.2) and days to maturity (-0.2). Cluster analysis revealed that Cluster III consists of 4 genotypes namely NL 1474, NL 1475, NL 1597 and Sorgadwari. This cluster represent with highest grain yield, number of spikes per meter square, number of grains per spike and grain weight per spike. Among the tested genotypes, NL 1474, NL 1475, NL 1597 and NL 1590 were found superior for grain yield and yield-related traits in comparison to three checks and could be recommended for hills of Sudurpaschim province after further testing in multi-environment and in farmer's field.

Evaluation of Growth-differentiation Factor-15 Level and few Physiological Parameters Patients with Diabetes Mellitus Type 2

The study included 90 subjects and is divided into two groups: The first group is the patient group, which consists of 45 patients with diabetes mellitus type two; 45 patients with diabetes mellitus type two were identified by specialized diabetes doctors by samples collection in outpatients clinic at Diabetes and Endocrine Center in Marjan Medical City in Hilla city, Babylon province from 1 November 2022 till 31 Januray 2023. The blood samples of this study were obtained from patients and controlled through drug 5 mL of blood by using medical sterile syringes from a brachial vein and placed in a gel tube and ethylenediaminetetraacetic acid (EDTA) tube. Then the gel tube was placed at room temperature for 30 minutes to coagulate the blood, and samples were centrifuged (3000 rpm/min) for 5 minutes to separate the serum from other components of the blood. The serum was withdrawn by micropipette and then placed in the eppendorf tubes in two repeaters and kept frozen at -20℃ for the determination of growth differentiation factor 15 (GDF 15), lipid profile and fasting blood glucose. The whole blood in the EDTA tube to determine HbA1C. The mean fasting blood sugar and hemoglobin A1c of diabetes patients is significantly higher at (p-value < 0.001) than that of controls. Diabetes patients had a significantly higher of serum lipid profile than the controls. Therefore, the mean of cholesterol, triglyceride, and low-density lipoprotein (LDL) and very low-density lipoprotein (VLDL) was highly significant (p < 0.001). The mean concentration of GDF-15 of patient groups was significantly increased than those matched groups of healthy control at (p < 0.001). In addition, the results also showed a highly significant increase (p < 0.001) in the mean of GDF-15 for the patient’s males and females in comparison with the control’s males and females. The correlation results indicated a statistically significant positive correlation in diabetic group between GDF-15 vs. FBS (r = 0.572, p = < 0.001) and HbA1c (r = 0.576, p = < 0.001). Positive non-significant correlations were demonstrated between GDF-15 vs. cholesterol (r = 0.131, p = > 0.05), triglyceride (TG) (r = 0.167, p = > 0.05), LDL (r = 0.38, p = > 0.05) and VLDL (r = 0.136, p = > 0.05). Negative non-significant correlation was between GDF-15 and high-density lipoprotein (HDL) (r = 0.137, p = > 0.05).

The Predictor Effect and Relationship Between Brain-Behavioral Systems, Cognitive Flexibility, Sensory Processing and Anxiety in Iranian Immigrant Students in Canada

Background: The rising prevalence of mental and psychological issues among immigrants has garnered increased attention due to the significant growth in immigrant populations in recent years. In this context, exploring the connection between psychological health, cognitive flexibility, brain-behavioral systems, and sensory processing in Iranian immigrants in Canada is becoming an essential research goal. Objectives: The aim of this study was to explore the relationships between psychological health, cognitive flexibility, brain-behavioral systems, and sensory processing among Iranian immigrants in Canada. Methods: A cross-sectional study design was used, gathering data from 400 Iranian students (198 males and 202 females) enrolled at universities in Canada and Iran. We collected participants' demographic details and assessed their psychological health, cognitive flexibility, brain-behavioral systems, and sensory processing through standardized instruments. Psychological health was evaluated using the Beck Anxiety Inventory, cognitive flexibility was measured with the Dennis and Vander Wall Cognitive Flexibility Questionnaire, and sensory processing was appraised via the adolescent/adult sensory profile. The Carver and White behavioral inhibition system (BIS)/behavioral activation system (BAS) scales were utilized to measure brain-behavioral systems. Statistical analyses, including correlation analysis and multivariate regression, were conducted to investigate the relationships among these variables. Results: The correlation analysis revealed significant positive associations between anxiety and low registration (r = 0.283, P < 0.001), sensory sensitivity (r = 0.442, P < 0.001), and sensory avoiding (r = 0.307, P < 0.001) in immigrant students. Anxiety also showed nonsignificant negative correlations with the behavioral activation system-drive (r = -0.042, P = 0.551) and behavioral activation system-reward responsiveness (r = -0.090, P = 0.203). The multivariate regression analysis found that low registration (B = 0.177, P = 0.036), sensory sensitivity (B = 0.336, P < 0.001), and cognitive flexibility (B = 0.119, P = 0.025) significantly predicted anxiety levels in immigrant students. An adjusted R-squared value of 0.191 indicated that these variables together explained 19.1% of the variance in anxiety levels. Conclusions: This study underscores the significant links between sensory processing patterns, cognitive flexibility, brain-behavioral systems, and anxiety among Iranian immigrant students. These findings highlight the need for interventions focusing on teaching cognitive skills strategies and increasing awareness of sensory needs to help reduce anxiety levels in this population.

Evaluation of Germplasm for Reproductive Stage Salinity Tolerance in Rice (Oryza sativa L.)

The current study was carried out to identify salt tolerant genotypes by screening 76 rice germplasm at reproductive stage salinity stress. The test entries were subjected to salt stress under field conditions and salinity was noted at different intervals of crop growth period i.e., 30 and 67 days after sowing and at the time of harvesting with the pH value of 5.4 and electrical conductivity of 4.3 dSm-1, 5.3 dSm-1and 7.2 dSm-1 respectively. The characters namely, salinity score, days to 50 percent flowering, plant height, panicle length, productive tillers/plant, number of filled grains/panicle, total number of grains/panicle, spikelet fertility and grain yield/plant were studied under saline conditions. Variability, heritability and genetic advance as percent of mean showed high genotypic and phenotypic coefficient of variation for grain yield plant-1indicating the presence of considerable amount of variation among the genotypes for potential yield improvement through selection. The trait grain yield per plant had high heritability coupled with high genetic advance as percent of mean indicating that it is regulated by additive gene action and therefore selection could be practiced based on phenotypic performance. Association studies under saline conditions, revealed favorable and significant correlation of grain yield per plant with days to 50% flowering, panicle length, plant height, total number of grains per panicle, number of filled grains per panicle and productive tillers per plant whereas, spikelet fertility and plant height on the other hand, recorded negative non-significant correlation, indicating the undesirable causes of salinity on plant growth and yield potential.

EVALUATION OF OXIDATIVE STRESS BIOMARKERS MDA AND SOD IN OCCUPATIONALLY EXPOSED ALUMINUM WORKERS IN ONITSHA, ANAMBRA STATE, NIGERIA

Aim: This research study was conducted to evaluate oxidative stress biomarkers using malondialdehyde (MDA) and superoxide dismutase (SOD) in aluminum workers exposed to occupational hazards. Research Method: The participants were recruited from an industrial area in Onitsha and divided into two groups: an exposure group composed of workers occupationally exposed to aluminum and a control group without exposure. The method of Gutteridge and Wilkins, (1982) was used for the estimation of malondialdehyde levels. SOD activity was measured according to the method as described by Misra and Fridovich, 1972. Data were analyzed using SPSS version 25 (IBM, USA, 2018). Independent T-test, descriptive, statistics, and Spearman correlation were used to analyze the data. Results: The results showed a significant increase in MDA in the aluminum workers group (3.53±1.04) as compared to the control group (1.65±0.58) (p<0.005). The SOD levels were reduced in the aluminum workers (21.55±3.85) as compared with the control samples (24.12±3.54) (p<0.005), indicating an elevation of oxidative stress. The study results revealed a significant positive correlation between MDA levels, age and duration of exposure. The SOD levels revealed a nonsignificant negative correlation with age and a significant correlation with duration of exposure. Conclusion: The findings indicate that long-term occupational exposure to aluminum can lead to increased oxidative stress, as indicated by higher MDA levels and lower SOD levels

Current knowledge and practice of post-stroke unilateral spatial neglect rehabilitation: a national survey of Nigerian physiotherapists

BackgroundUnilateral spatial neglect (USN) is a leading cause of disability and handicap in stroke survivors affecting functional recovery. Therapists’ knowledge and practice in post-stroke unilateral spatial neglect are key to the success of rehabilitation.AimThis study aimed to evaluate physiotherapists’ knowledge of USN and the current practice of USN management.MethodA cross-sectional study was undertaken among Nigerian physiotherapists (N = 240). An online structured questionnaire that assessed respondents’ knowledge, current practice, barriers, and enablers to post-stroke USN rehabilitation was administered.ResultsThe total knowledge score was 12.6 ± 4.75 on a scale of 25. Few physiotherapists (7.92%) demonstrated good knowledge of USN. Postgraduate certification (p = 0.001), clinical practice setting (p = 0.008), and working full time in neurorehabilitation (p = 0.033) were significantly associated with the therapist’s knowledge of USN. There was a nonsignificant positive correlation between the duration of practice in the neurorehabilitation setting (r = 0.02; p = 0.854) and USN knowledge. A nonsignificant minimal negative correlation between practice as a physiotherapist (r = − 0.02; p = 0.772) and USN knowledge was also noted. The age of physiotherapists showed no linear relationship with the therapist’s knowledge of USN (r = − 0.00; p = 0.992). Constraint-induced movement therapy (86.47%) was the most commonly used USN treatment, while Albert’s test (49.37%) was the most utilized screening tool for USN.ConclusionsVery few physiotherapists had good knowledge of USN. Participants’ knowledge increased as they attained higher education levels relating to neurological physiotherapy. These findings emphasize the need for specialist rehabilitation training for physiotherapy practice.

Hearing loss, gait and balance impairments and falls among individuals with sub-acute stroke: A comparative cross-sectional study

BackgroundThe impact of hearing loss in stroke is less explored. This study aimed to compare hearing loss in patients with sub-acute stroke with healthy controls and evaluate its association with gait and balance impairments and falls. MethodsThis study involved 78 ambulant sub-acute stroke patients and 78 age-sex-matched controls. Hearing loss was assessed with pure tone average, while gait and balance impairments were assessed with the Timed Up and Go test, Berg Balance Scale, Functional Gait Assessment and 10-m walk test (gait speed). Fall occurrence was evaluated by a self-report questionnaire. ResultsThe prevalence of hearing loss (pure tone average of >25 dB) was higher in stroke patients than in controls (64.1% vs. 35.9%; p < 0.001). The mean pure tone average of stroke patients showed a significant positive correlation with Timed Up and Go test (r = 0.357; p = 0.001) and fall occurrence (r = 0.253; p = 0.025), and a significant negative correlation with Berg Balance Scale (r = −0.299; p = 0.008) and Functional Gait Assessment (r = −0.452; p < 0.001). There was a non-significant negative correlation with gait speed (r = −0.166; p = 0.147). Multiple regression showed that mean pure tone average was associated with Timed Up and Go test (B = 0.096; 95%CI: 0.010, 0.183) and Functional Gait Assessment (B = −0.087; 95%CI: −0.157, −0.017), but not with gait speed (B = −0.003; 95%CI: −0.007, 0.001) and Berg Balance Scale (B = −0.058; 95%CI: −0.165, 0.049). ConclusionHearing loss is more prevalent among patients with sub-acute stroke compared with age-sex-matched controls. Hearing loss is also associated with gait and balance impairments and falls among sub-acute stroke patients. We recommend that hearing screening and rehabilitation be incorporated into post-stroke rehabilitation programmes as part of strategies to improve balance and gait and reduce or prevent falls.

Reading performance in school going children with visual function anomalies

To compare reading performance in children with and without visual function anomalies. This cross-sectional study was carried out from May 2021 to April 2022 in a tertiary eye hospital of Bangladesh. This study included patients with 6-15 years of age who visited at Vision Therapy clinic. CISS-score was used to identify the asthenopia complaints and reading difficulties while having a normal vision and normal retinal function only selected for recruitment. Reading error, accuracy and reading speed were assessed with an N-notation chart with an N6 target size and the time taken to complete the task was recorded with a stopwatch. Both univariate and bivariate tables are used for analysis. Statistics analysis was performed accordingly, and the level of significance used was at 0.05. Out of 200 subjects, 46.5% boys and 53.5% girls. Of the total, 15.5% had NVF. The mean age of the participants was 12.04 (±2.44) years. Children with AVF had a higher number of reading errors and non-significant negative correlation (AVF=7.64 (±5.19); NVF 6.55 (±3.67); (r = -1.00, p=0.157). Lower Reading accuracy was noted in AVF as correlated to NVF and non-significant negative correlation (AVF=86.11 (±14.84); NVF=86.43 (±13.12); (r= -0.008, p=0.912). Similarly, lower reading speed was noted in AVF as correlated to NVF and non-significant negative correlation (AVF=79.47 (±39.20) wpm; NVF=84.51±36.84 wpm; (r= -0.047, p=0.507). A statistically significant difference was seen between AVF and NVF (p=0.001 at a 95% Confidence Interval of the differences). Children in the 1 to 5 grades presented a higher risk of reading impairment than the 6 to 10grades. Higher reading speed (112±20.69wpm) was noted in 10 grade. In this study, it was observed that poor reading performance is linked to abnormal visual function in school-aged children, but visual function and reading performance are not positively related.

Effect of Weather Parameters on Population Dynamics of Bihar Hairy Caterpillar [Spilarctia (Spilosoma) obliqua Walker] in Mungbean [Vigna radiata (L.) Wilczek

The present investigation revealed that Bihar hairy caterpillar was first recorded during 32nd standard week (1.92 larvae/plant) which reached to its maximum during 41st standard week (11.93 larvae/plant) and there after gradually decreased up to 1.33 larvae/plant during 44th standard week.&#x0D; The maximum temperature showed non-significant positive correlation, minimum temperature and relative humidity showed non-significant negative correlation while rain fall showed significant negative correlation with the population buildup of Bihar hairy caterpillar.

Infrared Thermography as a Non-Invasive Tool to Assess Health Bio-Marks in University Students

Aim: To evaluate the relationship between cortisol concentrations (ng/ml) with body temperature, digital thermometer and thermal infrared gun (˚C). Infrared Thermography is a new and revolutionary way of measuring body temperature. Methodology: In this study data is collected about 65 individuals and extract blood samples from 50 students (25 males and 25 females). Results: Non-significant negative correlation was observed between cortisol concentrations (ng/ml) with body temperature of IRT of right eye-maximum (CC = -0.100; P = 0.490). Non-significant negative correlation was observed between cortisol concentrations (ng/ml) with body temperature of IRT of left eye-maximum (CC= -0.099; P = 0.495). Non-significant negative correlation was observed between cortisol concentrations (ng/ml) with body temperature of IRT of forehead-maximum (CC = -0.124; P = 0.413). A non-significant negative correlation is also observed between cortisol concentration (ng/ml) with body temperature of IRT of mean of left eye, thermal infrared gun and digital thermometer (˚C). Conclusion: Overall non-significant negative correlation is also observed between various concentrations with body temperature. Keywords: IRT, Cortisol, Body temperature, Digital thermal temperature, Infrared gun temperature

Perfluorooctane Sulfonate (PFOS) Negatively Impacts Prey Capture Capabilities in Larval Zebrafish.

Per- and polyfluoroalkyl substances (PFAS) are widely used in many industrial and domestic applications, which has resulted in unintentional human exposures and bioaccumulation in blood and other organs. Perfluorooctane sulfonate (PFOS) is among the most prevalent PFAS in the environment and has been postulated to affect brain functions in exposed organisms. However, the impacts of PFOS in early neural development have not been well described. We used zebrafish larvae to assess the effects of PFOS on two fundamental complex behaviors, prey capture and learning. Zebrafish exposed to PFOS concentrations ranging from 2 to 20 µM for differing 48-h periods were viable through early larval stages. In addition, PFOS uptake was unaffected by the presence of a chorion. We employed two different experimental paradigms; first we assessed the impacts of increasing organismal PFOS bioaccumulation on prey capture and learning, and second, we probed stage-specific sensitivity to PFOS by exposing zebrafish at different developmental stages (0-2 vs. 3-5 days post fertilization). Following both assays we measured the amount of PFOS present in each larva and found that PFOS levels varied in larvae from different groups within each experimental paradigm. Significant negative correlations were observed between larval PFOS accumulation and percentage of captured prey, whereas nonsignificant negative correlations were observed between PFOS accumulation and experienced-induced prey capture learning. These findings suggest that PFOS accumulation negatively affects larval zebrafish's ability to perform complicated multisensory behaviors and highlights the potential risks of PFOS exposure to animals in the wild, with implications for human health. Environ Toxicol Chem 2024;43:847-855. © 2023 SETAC.

Influence of work-related stress on patient safety culture among nurses in a tertiary hospital: a cross-sectional study

BackgroundOne of the global issues facing the nursing profession is work-related stress because it interferes with care quality and organisational competency. These kinds of stressful situations can cause damage to the mental ability of the affected individual resulting in low job productivity. In a Nigerian healthcare setting, patient safety is under-researched.AimThis study aimed to assess the influence of work-related stress on patient safety culture among nurses in a tertiary hospital.Materials and methodsThe study adopted a descriptive cross-sectional survey. The Population of the study was nurses who are currently serving as employees at Federal Medical Center Birnin-Kebbi. Proportional and systematic sampling methods were used in the selection of the sample of the study. The tools used for this study were adapted Hospital Survey on Patient Safety (HSOPS) and Nurses’ Occupational Stressor Scale. Ethical approval was obtained from the research ethical committee of the hospital.ResultsThe moderate stress experience was having the highest percentage (45.0%). The highest percentage of the nurses (69.9%) practised a moderate safety culture. There were weak or very weak significant negative correlations (P < 0.01) between patient safety culture practices and occupational stress across all the subscales of the nurses’ occupational stressors scale except in the occupational hazards subscale in which there was extremely weak and non-significant negative correlation. Work–family conflict was a significant predictor of patient safety culture, t (208) = -2.341, P < 0.05. Difficulty in taking leave was a significant predictor of patient safety culture, t (208) = -2.190, P < 0.05.ConclusionThere was a significant negative correlation between stress and safety practice which implies that as stress increased safety practice decreased. These study findings can be used to develop ongoing strategies and targeted interventions in addressing work-related stress.

COMPARING MAGNETIC RESONANCE ENTEROGRAPHY AND ENDOSCOPY FINDINGS TO QUANTATATIVE MAGENTIC RESONANCE IMAGING IN PEDIATRIC CROHN’S DISEASE

Abstract BACKGROUND In pediatric Crohn’s disease, endoscopy has remained the gold standard for diagnosis; however, Magnetic Resonance Enterography (MRE) is able to show inflammation of the bowel that a gastroenterologist cannot reach with endoscopy. For a standard MRE, a patient needs to ingest oral contrast, receive intravenous (IV) contrast and a spasmolytic agent, and hold his/her breath during portions of the study, which can be challenging in younger children. As shown in previous studies, quantitative Magnetic Resonance Imaging (MRI) can evaluate bowel motility in children with Crohn’s disease, showing that as motility decreases in the bowel, inflammation increases. A motility score obtained from GIQuant software (Motilent, UK) may allow existing MRE protocols to be shortened and can be done with free-breathing techniques and without IV contrast and the spasmolytic agent. AIM Our primary aim is to demonstrate that quantitative MRI, which uses the cine image to develop a motility score from GIQuant software, is as effective as standard MRE in assessing inflammation of the bowel. We secondarily hypothesize that the motility score will inversely correlate to the Endoscopic Biopsy Acute Histologic Inflammatory Score (eAIS), the Crohn’s Disease Endoscopic Index of Severity (CDEIS) score, and the MR Index of Activity (MaRIA) score. METHODS This was a retrospective study of 50 pediatric patients from Children’s Wisconsin with ileal and/ or cecal Crohn’s disease who underwent endoscopy and MRE within 7 days of each other without exposure to therapy. Cine images were used from patients’ previously obtained MREs to obtain a motility score using GIQuant. A cine image and GIQuant map example is shown in Figure 1. The relationships between motility score and MaRIA, eAIS, and CDEIS were then calculated by Spearman’s rank correlation coefficient (ρ). RESULTS MaRIA and motility scores inversely correlated (ρ = -0.66, p &amp;lt;.0001), which is seen in Figure 2. MaRIA positively correlated with CDEIS (ρ = 0.30, p= 0.03) and eAIS (ρ = 0.26, p = 0.07). The motility score showed a non-significant negative correlation with CDEIS (ρ = -0.17, p = 0.24) and eAIS (ρ = -0.23, p =0.11). CONCLUSION Quantitative MRI is as effective as standard MRE in identifying inflammation of the bowel in Crohn’s disease. The cine image is obtained much faster than standard MRE and without the use of intravenous contrast, spasmolytic agent, and breath-holding techniques, which is crucial for children who are too young to cooperate with current MRE protocols. Figure 1 MRE cine image with the Region of Interest in the terminal ileum identified via the polygon and the resulting Motility Map produced by GIQuant Figure 2 MaRIA and Motility scores of each patient in our cohort

Influence of Weather Factors on the Incidence of Major Insect Pests of Sesame (Sesamum indicum L.)

Population dynamics of major pests viz., web worm, Antigastra catalaunalis (Duponchel), leaf hoppers Orosius albicinctus (Distant) and gallfly Asphondilia sesami (Felt) infesting sesame was studied in Coimbatore, Tamil Nadu, India during Rabi and Kharif seasons of the year 2020. Correlation between the pest population, percent damage and weather parameters was analyzed and regression equations were developed. The incidence of leaf hoppers, web worm and gallfly on sesame crop during Rabi season started on 4th, 3rd and 7th Standard meteorological week (SMW) respectively. The peak attained on 8th,11th, and 11th SMW with population of leafhoppers and damage by web worm and gallfly (2.01/plant,60.04 percent and 49.68 percent) respectively during Rabi season. In case of leafhopper and web worm, minimum temperature (r=0.031r=0.373) had non-significant positive correlation whereas mean relative humidity (r=-0.02) registered non-significant negative correlation with leaf hopper and web worm significant negative correlation Gall fly incidence showed significant positive correlation with maximum and minimum temperature. Whereas in Kharif season, incidence of leafhoppers, web worm and gallfly on sesame crop started on 33rd, 32nd and 37th SMW respectively. The peak activity and incidence was noticed during 37th, 39th and 40th SMW for leafhoppers, web worm and gallfly respectively. The correlation between weather parameters and incidence of major pests followed a similar pattern to kharif season. Regression analysis data revealed that the multiple non-linear regression equations are sufficient to predict the pest population with prevailing weather parameters.

Study of digestive enzymes in marine fish, Terapon jarbua, from Pakistan.

Current analysis were performed to investigate the activity of various digestive enzymes, such as lipases, proteases and amylases in gut and their relationship to the other morphometric variables in a wild marine fish, Terapon jarbua. The descriptive data of the studied traits included fish weight, fish total length, gut weight, gut length, relative gut length, relative gut mass, Fulton's condition factor, standard length and Zihler's index. Gut length showed positive correlation with fish total length and gut weight, relative gut length (RGL) showed positive correlation with gut length. Relative gut mass (RGM) also showed positive correlation with total length (TL), gut weight (GW) and gut length (GL). Fulton's condition factor showed positive correlation with fish weight, while negative correlation with fish total length and relative gut mass. Standard length displayed positive correlation with gut weight and gut length while, it showed negative correlation with Fulton's factor. Zihler's Index displayed positive correlation with gut length, RGL and Zihler's RGM while, while showed negative correlation with Fulton's factor and fish weight. Lipase showed negative correlation with gut weight. Amylase and protease activity have no correlation with other studied traits. Lipase activity displayed negative significant correlation with gut weight. Lipase activity showed significantly negative effect on gut-weight. Amylase activity on y-axis (PC2) contributed 13% in variation but not significantly correlated with first two principal components. It showed non-significant negative correlation with fish weight, fish length and Fulton's factor while positive but not-significant correlation with other traits. Protease has positive and non-significant correlation with fish weight, RGL, Fulton's factor, lipase and amylase while non-significant negative correlation with all other traits.