Thyroid nodules, including both benign and malignant lesions, are the most common endocrine neoplasms. Most thyroid tumours are benign, with slow progresssion over time. Although surgery is the primary treatment method for benign thyroid nodules, the transoral endoscopic thyroidectomy vestibular approach (TOETVA) has recently gained popularity due to its higher probability of concealing scarThe study was conducted using a prospective descriptive method, with a convenient sample size. The study subjects were patients with transoral endoscopic thyroidectomy vestibular approach at the Department of Oncology and Palliative care, Hanoi Medical University Hospital from February to November 2023. Average age was 38.2 ± 9.0 years old; female accounts for 98.8%; the most common symptom in the study was neck tumour (64.2%); 92.6% of patients had palpable nodules clinically. Ultrasound showed 72.8% of patients with one tumour with an average tumour size of 26.9±11.6mm; the majority of patients have nodules ranked TIRADS 3 (69.1%). 64.2% of patients have moderate pain on the first day after surgery and 92.6% of patients had no pain on the 7th day post surgery,; complications included 5 cases of laryngeal nerve damage, 2 cases of hypoparathyroidism and 1 case of mental nerve damage; 8 patients had skin numbness in the surgical area, 3 patients had limited swallowing. The average hospital stay was 5.2 ± 1.7 days; 80.2% of patients were satisfied with post-operative care. Research shows that TOETVA is a safe method with a small percentage of postoperative complications and brings satisfaction in the postoperative process.