Well, seismic (2D and 3D) and AHe age data, complemented by field surveys, were analyzed with the objective of investigating the tectono-stratigraphic evolution of syn- and post-rift sedimentary basins in the eastern Kopeh Dagh Belt (NE Iran), a region well known for its important oil and gas occurrences. The study was focused on evaluating how and when the geometry of syn-rift structures influenced the development of the post-rift sedimentation. Our results show that the Middle Jurassic rifting stage influenced the geometry of the post-rift basins. Carbonate buildup of the Upper Jurassic (Mozduran reservoir) was formed in the low relief accommodation zones between the Middle Jurassic opposing half-grabens in parallel to the sedimentation of argillaceous carbonates within the adjacent troughs. This geometry was also transmitted to the Lower Cretaceous, affecting the deposition of a relevant siliciclastic system (Shurijeh reservoir). The role of rifting was crucial in the distribution of reservoir facies and the generation of the structural-stratigraphic traps in the study area, which were also affected by late tectonic inversion. Uplift and denudation is likely to have occurred up to Late Miocene.