In Syria, soil erosion (SoEr) by water is one of the major challenges for sustainability. Thus, the main goals of this research were to evaluate the spatial changes of SoEr between 2000 and 2018 in the whole coastal basin (CB) of Syria and to provide a soil water erosion risk map for the study area. For this purpose, monthly rainfall data, the SoilGrids dataset, satellite image derived NDVI layers, and Digital Elevation Model (DEM) were collected. Through the integration of these layers into the Revised Universal Soil Loss Equation (RUSLE), under a Geographic Information System (GIS), soil loss was assessed. Also, the contribution of land cover changes and R factor on SoEr were evaluated. The outcomes of this assessment illustrated that the R factor ranged from 800 to 2600MJmmha-1h-1yr-1, while the soil erodibility factor (K factor) ranged from 0.048 to 0.035 ton ha MJ-1mm-1. The C factor (vegetation coverage) values ranged between 0.07 and 1 with a spatial average value of 0.44 for the 2000-2009 period and 0.39 for the 2010-2018 interval. The output of RUSLE revealed that average annual SoEr was of 21.35 ton ha-1 y-1 (± 38) for 2000-2009 and 22.47 ton ha-1 y-1(± 41.8) for 2010-2018. Interestingly, the increased SoEr caused by the R factor was dominant (34.65%), followed by changes in both C factor and R factor (13.34%). However, decrease of SoEr rates is due to the increase of the C factor accounting for 36.82% of the CB. The outcome of this research can provide constructive spatial insights for rehabilitation plans for the post-war phase of Syria.