A gravity-driven, thin, incompressible liquid film flow on a non-uniformly heated, slippery inclined plane is considered within the framework of the long-wave approximation method. A mathematical model incorporating variation in surface tension with temperature has been formulated by coupling the Navier–Stokes equation, governing the flow, with the equation of energy. For the slippery substrate, the Navier slip boundary condition is used at the solid–liquid interface. An evolution equation is formed in terms of the free surface, which includes the effects of inertia, thermocapillary as well as slip length. Using the normal mode approach, linear stability analysis is carried out and a critical Reynolds number is obtained, which reflects its dependence on the Marangoni number Mn as well as slip length δ. This depicts that δ and Mn both have the destabilization effect on the flow field. The linear study also reveals that the inertia force has a negligible effect compare to the thermocapillary or slip. In addition, the study highlights a critical Marangoni number at which the instability sets in when the thermocapillary stress attains a critical value. The method of multiple scales is used to investigate the weakly nonlinear stability analysis of the flow. The study interprets that the variation of Mn and δ have substantial effects on different stable/unstable zones. It also shows that within a considered parametric domain, the unconditional stable zone completely vanishes for any value of Mn, when the slip length δ attains a critical value. The study also divulges that in the subcritical unstable (supercritical stable) zone the threshold amplitude (ζa) decreases (increases) with the increment of Mn and δ. Further, we discussed the spatial uniform solution of the complex Ginzburg–Landau equation for sideband disturbances. Employing the Crank–Nicolson method, the nonlinear evolution equation of the free surface is solved numerically in a periodic domain, considering the sinusoidal initial perturbation of small amplitude. The nonlinear simulations are found to be in good agreement with the linear and weakly nonlinear stability analysis. The evolution of the maximum hmax and minimum hmin thickness amplifies, for small change of Mn and δ. Further, it shows that the influence of the thermocapillary force amplifies the destabilizing nature of δ. The traveling wave solution confirms the existence of a fixed point for the considered parametric domain, chosen from the experimental data. Finally, the Hopf bifurcation of the fixed point exhibits that the nonlinear wave speed at the transcritical point increases as δ increases but decreases as Mn increases. The noteworthy result which arises from the study is that a transcritical Hopf bifurcation exists if the slip length δ>max16Mn−13,12Mn−23−Mn.