Dietary Supplements Research Articles

The efficacy of dietary supplements on health status and performance of football players: a systematic review.

This study aimed to review the efficacy of commonly used supplements on the health status and performance of football players. We searched several databases forrelevant publications published in English upto June 2024 using keywords such as nutritional supplementation, performance, football, and football players. The available literature indicated that l-arginine supplements may improve cardiovascular function, ventilation, the serum level of lactate, and maximal oxygen consumption (VO2 Max) of football players. Branched-chain amino acids (BCAAs) may improve multiple-choice reaction time. Creatine supplements improve jumping, sprinting, change of direction speed, and reduce fatigue. Among thevitamins, vitamin D improves the serum level of injury-related hormones such as cortisol and testosterone. Bvitamins reduce the level of blood lactate in the recovery periods. Vitamin E and vitamin C may improve performance by decreasing oxidative stress and increasing the antioxidant capacity and oxygen delivery to exercising skeletal muscles. Iron supplementation improves endurance capacity. Further studies are warranted to confirm the effects of the supplements on football players, to identify the appropriate dosage ofthe supplements and also to determine their mechanism ofaction.

Supplement Use among Hypertensive Patients in Two Rural and Two Urban Health Centers in Guyana, South America

Objective: This study aimed to comparatively assess the knowledge and practices related to the use of dietary supplements as adjunctive treatment and management for hypertension among patients attending two rural and two urban health centers in Guyana. Methods: A cross-sectional, mixed-methods design was employed to evaluate the prevalence, patterns, and motivations for dietary supplement use among 144 hypertensive adults (71 urban, 73 rural) in Guyana, with a focus on the influence of cultural practices on healthcare approaches. Data were collected using a structured questionnaire, which was pretested in a pilot study to ensure validity and reliability. Results: The study sample consisted of 64% female and 36% male participants, with the majority (57%) being over 60 years of age. Urban participants predominantly used vitamin and mineral supplements, demonstrating a statistically significant association between supplement use and blood pressure classification (χ² = 7.16, p = .007). Conversely, rural participants more frequently relied on herbal remedies, particularly for preventive purposes. Conclusion: The findings highlight the need for larger-scale, longitudinal studies to comprehensively explore the interplay between cultural influences, dietary supplement use, and hypertension management in Guyana. Such research is essential for informing the development of culturally sensitive public health interventions to enhance hypertension care in diverse populations.

Effects of social media influencer credibility on their followers’ dietary supplement evaluations and purchase intentions

ABSTRACT On the basis of the source credibility model, this study investigated the effects of various dimensions of social media influencer (SMI) credibility on followers’ perceptions of the nutritional value, safety, and health benefits of endorsed dietary supplements (DSs) and the effects of such perceptions on purchase intentions. Data were collected from 418 Taiwanese consumers who followed an SMI that had endorsed DSs. Structural equation modeling was employed to analyze the hypothesized relationships. The results revealed that SMI trustworthiness and attractiveness positively influenced followers’ perceptions of the nutritional value and safety of the endorsed DS. However, SMI expertise affected only perceived nutritional value but not safety. Moreover, perceived nutritional value and safety contributed to perceptions of health benefits, ultimately leading to higher purchase intentions. This study contributes to the literature by elucidating how the dimensions of SMI credibility influence followers’ perceptions of an endorsed DS’s nutritional value, safety, and health benefits.

Dietary Supplement Use in Competitive Spanish Football Players and Differences According to Sex

Dietary Supplement Use in Competitive Spanish Football Players and Differences According to Sex

Antisecretory factor in severe traumatic brain injury (AFISTBI): protocol for an exploratory randomized placebo-controlled trial

BackgroundDespite recent advances in neuroimaging and neurocritical care, severe traumatic brain injury (TBI) is still a major cause of severe disability and mortality, with increasing incidence worldwide. Antisecretory factor (AF), commercially available as Salovum®, has been shown to lower intracranial pressure (ICP) in experimental models of, e.g., TBI and herpes encephalitis. The aim of this study is to assess the effect of antisecretory factors in adult patients with severe TBI on ICP and inflammatory mediators in extracellular fluid and plasma.Methods/designThis is a single-center, randomized, placebo-controlled clinical phase 2 trial, investigating the clinical superiority of Salovum® given as a food supplement during 5 days to adults with severe TBI (Glasgow Coma Scale (GCS) < 9), admitted to the neurocritical intensive care unit (NICU) at Skane university hospital, Lund, Sweden. All patients with GCS < 9 and clinical indication for insertion of ICP-monitor and microdialysis catheter will be screened for inclusion and assigned to either the treatment group (n = 10) or placebo group (n = 10). In both groups, the primary outcome will be ICP (mean values and change from baseline during intervention), registered from high-frequency data monitoring for 5 days. Secondary outcomes will be inflammatory mediators in plasma and intracerebral microdialysis perfusate days 1, 3, and 5 during trial treatment.Trial registrationClinicalTrials.gov NCT04117672. Registered on September 17, 2017. Protocol version 6 from October 24, 2023.

Generation of novel prebiotic oligosaccharide pools from fiber drives biological insight in bacterial glycan metabolism.

Prebiotic oligosaccharides are dietary supplements that modulate the intestinal gut microbiome by selectively nourishing subsets of the microbial community with a goal to enhance host health. To date, the diversity of polysaccharide compositions in the fiber consumed by humans is not well represented by the limited scope of oligosaccharide compositions present in current commercial prebiotics. Recently, our UC Davis group developed a novel method to generate oligosaccharides from any polysaccharide fiber, termed Fenton's Initiation Toward Defined Oligosaccharide Groups (FITDOG). Using this method, sugar beet pulp (SBP) was transformed into sugar beet oligosaccharides (SBOs) composed of arabinose- and galactose-containing oligosaccharides. Fecal fermentations of SBO and SBP produced similar shifts in donor-specific bacterial communities and acid metabolite profiles with a general enrichment of Bacteroides and Bifidobacterium. However, in vitro tests revealed more Bifidobacterium strains could consume SBO than sugar beet arabinan, and specific strains showed differential consumption of arabinofuranooligosaccharides or galactooligosaccharide (GOS) portions of the SBO pool. Genomic and glycomic comparisons suggest that previously characterized, arabinan-specific, extracellular arabinofuranosidases from Bifidobacterium are not necessary to metabolize the arabino-oligosaccharides within SBO. Synbiotic application of SBO with an SBO-consuming strain Bifidobacterium longum subsp. longum SC596 in serial fecal enrichments resulted in enhanced persistence among 9 of 10 donor feces. This work demonstrates a novel workflow whereby FITDOG creates novel oligosaccharide pools that can provide insight into how compositional differences in fiber drive differential gut fermentation behaviors as well as their downstream health impacts. Moreover, these oligosaccharides may be useful in new prebiotic and synbiotic applications.IMPORTANCEPrebiotics seek to selectively alter the host microbiome composition or function, resulting in a concurrent health benefit to the host. However, commercial prebiotics represent a small fraction of the diversity of food polysaccharide compositions. In this work a novel method, Fenton's Initiation Toward Defined Oligosaccharide Groups (FITDOG) was used to generate an oligosaccharide pool from sugar beet pulp (SBP). Sugar beet oligosaccharides (SBOs) resulted in similar changes to SBP in fecal enrichments; however, SBO could be consumed by more beneficial bifidobacterial strains than the cognate polysaccharide. These results demonstrate how the details of glycan structure have a profound influence on how gut bacteria metabolize food carbohydrates. The implications of this work are relevant to understanding how different dietary sources influence the human microbiome and extend to developing novel oligosaccharide pools for prebiotic applications.

Complete genome sequencing and probiotic characterization of promising lactic acid bacterial strains isolated from dairy products in Egyptian markets

BackgroundProbiotics refer to live bacteria that, when administered in a sufficiently, exert a beneficial influence on human health. Due to the probiotics' beneficial health advantages, dietary supplements are expanding rapidly as a self-care interest worldwide. It may be beneficial to administer probiotic strains resistant to antibiotics concurrently with an antibiotic treatment. Our study investigates nineteen dairy products collected from Egyptian markets, isolated, identified and underwent a characterization for probiotic features under demanding circumstances as NaCl, acid and bile salt environments. The antibiotic sensitivity test was performed later to the antimicrobial assessment against widespread both negative and positive gram-stained bacteria infecting humans, along with the antiviral evaluation against (SARS-CoV-2), the virus that has disturbed the world recently.ResultsOut of nineteen investigated isolates, five potential probiotic isolates were examined for probiotic characteristics. Our tested samples were of dairy origin (yogurt, cottage-cheese and sour milk) in Egypt, were identified as Lactobacillus delbrueckii subsp. bulgaricus, Streptococcus thermophilus and Pediococcus acidilactici. These promising isolates had withstood stressful factors, such as NaCl, acid, bile salts, and the antimicrobial advance. The genomes were characterized for the physiology, safety, and efficacy of these isolates for probiotic qualities plus the presence of mobile genetic components and prophages that influence the genome's flexibility. They lack virulence factors and pathogenicity, rather than the lack of antibiotic resistance genes.ConclusionThree promising isolates underwent complete genome sequencing with high-throughput second generation technology followed by comprehensive bioinformatic analysis. The results showed that our isolates possess traits enabling resilience to antimicrobial effects and stress factors that might cause problems in the human gut. Several trustworthy genomic analysis methods were used to confirm and provide detailed illustrations of all traits. Genomic analyses confirmed the presence of stable genomes due to including mobile genetic components such as phages and CRISPR clusters, which validate their quality and safe usage for human health.

Preventive role of Pastinaca sativa in mitigating metabolic dysfunction-associated steatotic liver disease via modulation of metabolic endotoxemia

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a leading global liver disorder. Parsnip (Pastinaca sativa), rich in dietary fiber and medicinal properties, has shown health benefits, but its effects on MASLD are largely unexplored. This study evaluated the prebiotic and anti-MASLD effects of parsnip root water-soluble extract (PRE) in a mouse model. Mice fed a high-fat diet with 50 or 100 mg/kg PRE for eight weeks showed reduced fat accumulation, improved serum metabolic profiles, and decreased liver injury markers. PRE also lowered hepatic lipogenic protein levels induced by the high-fat diet. Additionally, PRE enhanced gut health by reducing endotoxins, improving intestinal permeability, and upregulating tight junction proteins. These results indicate that PRE can improve gut health, prevent MASLD, and support its potential as a dietary supplement to enhance metabolic health.

Dietary lipid constraints of Arthrospira platensis for survival and growth of Daphnia magna

ABSTRACT Arthrospira (previously Spirulina) is a filamentous cyanobacterium used as a dietary supplement for humans and animals because of its high protein content and the production of various bioactive compounds. However, this “superfood” is unsuitable as a sole resource for Daphnia magna, possibly because it lacks essential biochemicals. We explored possible lipid limitation of D. magna feeding on A. platensis by supplementing with cholesterol and/or the long-chain polyunsaturated fatty acid (PUFA), eicosapentaenoic acid (EPA). Daphnids were reared on long-filament (untreated), or short-filament (fragmented) A. platensis supplemented with cholesterol- and/or EPA-containing liposomes. For comparison, daphnids were fed Chlamydomonas reinhardtii (standard algal food). D. magna reared on cholesterol-supplemented A. platensis survived throughout the study period, grew well, and produced eggs better than those grown on Chlamydomonas reinhardtii, whereas D. magna raised on A. platensis supplemented with EPA did not survive as long, demonstrating that sterol limitation is the primary factor explaining the inadequate quality of A. platensis as food for D. magna. The lipid analysis also showed that no sterol was detected in A. platensis, whereas ergosterol and fungisterol were found in C. reinhardtii. Supplementing A. platensis with both cholesterol and EPA enhanced growth and reproduction, implying that A. platensis also has dietary PUFA limitations, which is important once sterol requirements are met. Because sterol limitation has serious consequences on zooplankton life history performance, incorporating dietary lipid limitation as a potential barrier for energy and carbon flow is crucial to enhance our understanding of food web dynamics and ecosystem functioning.

Potential role of dietary white poplar (Populus alba L.) in stimulating growth, digestion, and antioxidant/immune status of Nile tilapia (Oreochromis niloticus)

The potential use of feed supplements as immune-stimulant and growth-promoting agents in fish diets has drawn much attention. The current research investigated the effects of feeding Nile tilapia (Oreochromis niloticus) on white poplar (Populus alba L.) (WP) leaves powder as a dietary supplement on the growth, digestive functions, immune, and oxidant-antioxidant parameters. In addition, the fish resistance against the Aeromonas sobria (A. sobria) challenge was investigated. For 60 days, fish (n = 160; 34.61 ± 0.16 g) were divided equally into four groups, each had four replicates. Fish were fed on four isonitrogenous and isolipidic diets supplemented with varying levels of WP; 0 g/kg (WP0, crude protein (CP) = 37.18%; crude lipid (CL) = 9.98%), 2 g/kg (WP2, CP = 37.22%; CL = 9.56%), 4 g/kg (WP4, CP = 36.95%; CL = 9.47%), and 6 g/kg (WP6, CP = 36.88%; CL = 9.33%), where WP0 was the control diet. The results revealed that WP diets substantially boosted the growth (final body weight, weight gain, and specific growth rate) with an improvement of feed conversion ratio of Nile tilapia in a level-dependent manner with the WP6 group attaining the best outcomes. WP diets improved the amylase (4–6 g/kg level) and lipase (2–6 g/kg level) activity and the intestinal morphometric measures (2–6 g/kg level), where the WP6 group recorded the highest values. WP diets increased the growth hormone (2–6 g/kg level) and reduced leptin hormone and glucose levels (2–6 g/kg level). WP diets boosted the immune-antioxidant indices (total protein, albumin, globulin, complement 3, lysozyme, nitric oxide, total antioxidant capacity, glutathione peroxidase, and catalase) in a level-dependent manner and the WP6 group attained the highest values. All experimental groups exhibited 100% survival at the end of the feeding trial. During the A. sobria challenge, the survival of fish was improved in a level-dependent manner (2–6 g/kg) (80%, 85%, 95%, respectively) compared to the control (70%), where the WP6 group recorded the highest survival. Noteworthy, WP diets especially at a level of 6 g/kg can be used as a feed supplement for improving the health, growth, immune-antioxidant functions, and disease resistance of Nile tilapia.

Comparative Metabolic Profiling and Biological Evaluation of Essential Oils from Conocarpus Species: Antidiabetic, Antioxidant, and Antimicrobial Potential

Essential oils (EOs) are a diverse source of bioactive compounds with remarkable therapeutic potential. Despite their significance, Conocarpus EOs have been largely underexplored. This study provides a novel comparison of the metabolic profiles and biological activities of EOs from C. lancifolius, C. erectus green, and C. erectus silver leaves cultivated in the United Arab Emirates (UAE), offering unique insights into their distinct bioactive properties and potential therapeutic applications. EOs were extracted via hydro-distillation, analyzed using gas chromatography–mass spectrometry (GC-MS), and subjected to chemometric analysis. Their antioxidant (2,2-diphenyl-1-picrylhydrazyl (DPPH) and ferric reducing ability of plasma (FRAP) assays), antidiabetic (α-amylase and α-glucosidase inhibition), acetylcholinesterase (AChE) inhibition and antimicrobial activities were assessed. A total of 92 metabolites were identified, with heptacosane and nonacosane as key species discriminants. C. lancifolius EO showed the strongest α-amylase (IC50 8.75 ± 0.54 µg/mL) and α-glucosidase (IC50 22.31 ± 0.92 µg/mL) inhibitory activities, while C. erectus silver demonstrated superior antioxidant capacity (IC50 349.78 ± 8.26 µg/mL, DPPH assay). C. lancifolius EO exhibited the best antimicrobial activity, particularly against Staphylococcus aureus (MIC 625 µg/mL). C. erectus silver EO inhibited E. coli and C. albicans (MIC 625 µg/mL). In contrast, C. erectus EOs showed no activity against Aspergillus niger. These findings highlight the potential of Conocarpus EOs as antioxidants and for managing diabetes that may be utilized either in nutraceuticals, dietary supplements or even in pharmaceutical formulations. Moreover, owing to significant antimicrobial activities, the EOs may be added to medical disinfectants and several pharmaceutical products. However, further, in vivo validation and pharmaceutical exploration is still needed.

Nutrients and Nutraceuticals from Vitis vinifera L. Pomace: Biological Activities, Valorization, and Potential Applications

Grape pomace, also known as wine pomace, is a by-product of winemaking that has traditionally been discarded. However, recent studies have highlighted its rich nutritional and bioactive potential, positioning it as a promising resource for various applications in the functional food, pharmaceutical, and cosmetic sectors. This review explores the nutrient and nutraceutical contents of grape pomace, including its high levels of polyphenols, dietary fiber, vitamins, minerals, and melatonin. The biological activities of grape pomace, such as antioxidant, anti-inflammatory, antimicrobial, and anticancer effects, are also discussed, emphasizing its potential as raw material endowed with multifunctional properties. Additionally, the valorization of grape pomace as a food supplement and for the development of cosmetics is examined, focusing on its incorporation into dietary products and skincare formulations. The growing interest in the sustainable utilization of grape pomace is underscored, highlighting its significant role in promoting human health and contributing to a circular economy.

A step forward in enhancing the health-promoting properties of whole tomato as a functional food to lower the impact of non-communicable diseases

Nutritional interventions facilitating the consumption of natural, affordable, and environment-compatible health-promoting functional foods are a promising strategy for controlling non-communicable diseases. Given that the complex of tomato micronutrients produces healthier outcomes than lycopene, its major antioxidant component, new strategies to improve the health-supporting properties of the berry are ongoing. In this context, a whole tomato food supplement (WTFS), enriched by 2% olive wastewater containing a complex of healthy nutrients with converging biologic activities, has recently been developed, which is superior to those present in tomato commodities or obtained with whole tomato conventional processing methods. WTFS equals the antioxidant activity of N-acetyl-cysteine and interferes with multiple inflammation and cellular transformation-sustaining metabolic pathways. In interventional studies, WTFS inhibits prostate experimental tumors and improves benign prostate hypertrophy-associated symptoms with no associated side-effects. Although WTFS may be susceptible to further improvements and clinical scrutiny, its composition embodies the features of advanced functional foods to ease adherence to dietary patterns, that is, the Mediterranean diet, aimed at contrasting and mitigating the low-grade inflammation, thus being interceptive or preventive of non-communicable diseases.

Exploring the functional diversity and metabolic activities of the human gut microbiome in Thai adults in response to a prebiotic diet.

Exploring dietary methods to alter microbial communities and metabolic functions is becoming an increasingly fascinating strategy for improving health. Copra meal hydrolysate (CMH) is alternatively used as a gut health supplement. However, the functional diversity and metabolic activities in gut microbiome in relation to CMH treatment remain largely unknown. Therefore, this study aimed to identify key predominant groups of bacterial species toward diversified metabolic functions, activities, and routes using metaproteomics. As a result, the integrative analysis of metaproteomic data revealed that seven key families across 11 dominant gut bacterial species were concerted. Consistently, across 76,206 proteins assigned to the metabolism of the 255,964 annotated proteins, short-chain fatty acid (SCFA) biosynthesis, lipopolysaccharide (LPS) biosynthesis, and bile acid (BA) metabolism were positively associated with CMH. Further identification of cooperative metabolic routes promisingly highlighted the importance of glycolysis/gluconeogenesis, tricarboxylic acid (TCA) cycle, inositol phosphate metabolism, steroid hormone biosynthesis, O-antigen repeat unit biosynthesis, and chloroalkane and chloroalkene degradation. This work presents an initial study of metaproteomics associated with prebiotic diet in a Thai population-based cohort in a developing Southeast Asian country.IMPORTANCEStudies primarily focused on the impact of CMH on gastrointestinal symptoms and gut microbial compositions. However, as the field moves toward understanding the relationship between microbiome and diet in relation to gut health, it is critical to evaluate how changes in metabolic activities relate to cooperative metabolic routes in the gut microbiome for promoting human health. Through the use of metaproteomics, our findings highlighted the key predominant groups of bacterial species, potential proteins, and their metabolic routes involved in gut metabolism. This study provides comprehensive insights into the fundamental relationship between microbiome and dietary supplements and suggests that metaproteomics is a powerful method for monitoring metabolic functions, activities, and routes in the gut microbiome.

The possible effects of chili peppers on ADHD in relation to the gut microbiota

Attention deficit hyperactivity disorder (ADHD) is a common neurodevelopmental disorder, which is characterized by inattention, impulsivity and hyperactivity. Although the etiology and pathogenesis of ADHD are not fully understood, existing studies have shown that it may be related to genetic factors, environmental factors, abnormal brain development, and psychosocial factors. In recent years, with the concept of microbioa-gut-brain axis (MGBA), more and more studies have begun to pay attention to the effect of gut microbiota on ADHD. Dietary structure can significantly change the diversity and abundance of gut microbiota. Therefore, dietary supplements or food additives to regulate gut microbiota have become one of the potential ways to treat ADHD. Peppers, as an important dietary component, have potential value in regulating gut microbiota. Among them, capsaicin (8-methyl N-vanillyl-6-noneamide, CAP), as a key active component of peppers, has been shown to have potential therapeutic effects on central nervous system (CNS) diseases such as Parkinson’s disease, epilepsy, and depression. In addition, much attention has been paid to the beneficial effects of CAP on gut microbiota. Chili peppers contain not only CAP, but also rich in vitamin C and fatty acids, all of which may ameliorate ADHD by modulating the gut microbiota. This finding not only provides a potential treatment for ADHD, but also provides a new perspective to expand the research and clinical treatment of ADHD pathogenesis. Although current research on the potential therapeutic effects of chili peppers on ADHD is still at an early stage and requires further verification through larger-scale and more rigorous controlled studies, its potential clinical value cannot be ignored.

Effects of therapeutic factors on brown adipose tissue in order to correct obesity

Adipose tissue has morphological heterogeneity. Currently, five types of fat cells are known: white, beige, brown, yellow and pink adipocytes. In the future, we will consider white, beige and brown adipocytes. The main pathological role in the development of obesity and a number of other metabolic diseases is played by white adipose tissue. The function of energy storage in white adipocytes is well known. However, in pathological conditions, the mass of white fat can increase significantly, amounting to more than 70% of the total body weight. In addition, white adipocytes are prone to inflammation and pathological production of biologically active substances - adipokines. Many adipokines negatively affect musculoskeletal and bone tissues, exacerbate systemic chronic inflammation and the severity of polymorbid pathology. At the same time, brown adipose tissue, due to its pronounced ability to heat production (thermogenesis), has protective properties. Activation of brown adipose tissue and stimulation of the transformation of white adipocytes into brown ones (the so-called “browning”) with the help of physical activity, medications and dietary supplements seems promising. These methods can be successfully used to combat overweight and obesity. In addition, modern advances in genetics and transplantology allow us to hope for the future use of brown adipocyte transplantation in patients who suffer from severe obesity. Research on the interrelationships of adipose tissue, muscles, cardiovascular, nervous, endocrine and other body systems continue. Undoubtedly, there are many interesting scientific discoveries to be made in medical science.

Unlocking the potential of l-α-glycerylphosphorylcholine in the food industry: From safety approvals to market prospects.

With the exacerbation of global population aging, age-related neurodegenerative disorders have been posing an increasing public health concern. l-α-Glycerylphosphorylcholine (l-α-GPC) has demonstrated significant therapeutic potential for mental health-related disorders and possesses promising market prospects. Recently, l-α-GPC has been successively approved as a new food resource in Canada (2023) and in China (2024). These policies pointed out the recognized safety and utility of l-α-GPC. The utilization of l-α-GPC in dietary supplements and health foods could be a convenient option for early intervention strategies to potentially delay or mitigate the progression of neurodegenerative disorders. Additionally, other unique nutritional benefits of l-α-GPC have been highlighted, further expanding its application in food industry. Encouraged by the policy incentives, there is likely to be a new upsurge in the research interest surrounding l-α-GPC. To fully capitalize on these emerging opportunities, we present a comprehensive review of l-α-GPC. The chemical properties, pharmacological characteristics, safety assessments, and preparation methods of l-α-GPC were summarized. A brief outlook on the future perspectives and unsolved challenges was also proposed.

Influence of storage duration on the amount of iodine in food ingredients

Iodine has an undeniable effect on the vital systems of the human body, and its deficiency or excess can have harmful consequences. Measures for the mass prevention of iodine deficiency diseases mainly include the fortification of publicly available food products with iodine-containing food ingredients. The results of the study showed that the amount of iodine in ingredients such as iodized salt and dried kelp can decrease during storage, even if storage conditions and expiration dates are met. Quantitative analysis of iodine and iodotyrosines in dietary supplements containing the organic form of iodine showed good stability of the compounds throughout the shelf life. Quantitative analysis of molecular iodine in the objects was carried out using the voltammetric method, based on the results of which “box-and-whisker” diagrams were compiled, displaying the measurement error, with a tendency for iodine in the research objects to decrease during storage. Quantitative analysis of the organic form of iodine (iodotyrosines) was carried out by high-performance liquid chromatography with mass spectrophotometric detection. Based on the results obtained, histograms were compiled, reflecting changes in the ratio of monoiodotyrosines and diiodotyrosines and a decrease in the concentration of iodotyrosines depending on the shelf life.

Correction of nutritional status in a comprehensive program for the prevention and treatment of sarcopenic obesity

Sarcopenic obesity is a complex condition characterized by a combination of obesity and sarcopenia. This pathology has a significant impact on the health and quality of life of the elderly and old people, increasing the risk of chronic diseases and impairing physical functions. Nutritional status plays a key role in maintaining the health and functional ability of older people, influencing the development of sarcopenia and obesity. Understanding the relationship between sarcopenic obesity and nutritional status is critical for developing prevention and treatment strategies. Our scientific article covers the various mechanisms of development of sarcopenic obesity and the influence of nutritional status on sarcopenic obesity, and also examines the role of various nutrients and dietary supplements in the management of this condition. Our scientific article highlights the need for a comprehensive approach to the treatment and prevention of sarcopenic obesity among elderly and elderly patients to improve overall health and quality of life.

Harnessing Sacha Inchi By-Products: Innovations in Functional Food Development.

Sacha inchi (Plukenetia volubilis L.), native to the Amazon rainforest, is widely known for its oil-rich seeds. Its by-products, particularly the press cake, husks, and shells left after oil extraction, have significant nutritional and functional potential. These by-products contain high levels of proteins, dietary fiber, and bioactive compounds that can be repurposed to develop functional foods, nutraceuticals, and dietary supplements. This review article provides a detailed overview of the composition of sacha inchi by-products, recent findings on optimizing extraction processes for proteins, bioactive peptides, and antioxidant compounds, and product innovations using sacha inchi residues. It highlights the health benefits of consuming these products, such as functional bakery items and plant-based beverages with high sensory acceptance, protein hydrolysates with antioxidant and anti-inflammatory properties, beneficial effects on gut microbiota, and oligosaccharides with prebiotic properties, positioning sacha inchi by-products as key ingredients for developing plant-based nutraceutical and functional products. Additionally, the article emphasizes the potential of these by-products to contribute to a circular economy, reduce waste, and align with global efforts to achieve Sustainable Development Goals (SDGs) related to health, sustainable production, and environmental impact.