methods of case ascertainment. A wide range of incidence was reported internationally in 24/35 (68.5%) articles, with higher incidence in Japan, Taiwan and French Polynesia. There was insufficient evidence to suggest seasonal variation of BA incidence. Overall survival rates at 10 years range from 66.7% to 89%. Native liver survival rates range from 20.3% to 75.8% at 1–3 years, from 32% to 59.7% at 5 years and from 24% to 52.8% at 10 years following diagnosis. Early hepatoportoenterostomy is a predictor of improved NLS if performed <60 days. There was insufficient evidence to recommend centralization of procedure to high case volume centers. Infant stool color card was reported effective for early detection resulting in early Kasai and improved NLS in Taiwan, but no other jurisdiction. Conclusion: Incidence of BA varies widely worldwide. Age at Kasai operation was reported as a predictive factor for improved NLS. Centralization of procedure to high case volume centers is controversial and cannot be recommended based on current literature. Early diagnosis and subsequent early corrective surgery could be achieved by the infant stool color card. Global implementation of such a tool may help improve outcomes of BA.