National Sources Research Articles

Approach to HIV Prevention in Cuba for Men Who Have Sex with Other Men

This paper describes the main interventions for the prevention of human immunodeficiency virus infection, aimed at men who have sex with men, who constitute a risk group for acquiring the disease. For its preparation, the scientific literature published in national and international sources and documents considered relevant to the subject was selected. The analysis and recommendations focused on the health sector and the group of men who have sexual relations with other men. The approaches to the human immunodeficiency virus in Cuba are considered among the high-impact prevention programs, prepared both by civil society, through subsidies from the World Fund to Fight AIDS, Tuberculosis and Malaria, as well as by technicians from the National Program for Prevention and Control of STIs-HIV/AIDS. They include personalized service packages, which contain structural, biomedical and behavioral elements for key population groups in the social contexts where they are most needed. As is well known, the risk for each individual depends on their practices and not on the group to which they belong. These offer a common base for the development and promotion of effective programs for prevention, which allow organizing efforts directed at key populations, especially men who have sex with other men, and in this way reduce the number of new infections each year.

Coverage and similarity of bibliographic databases to find most relevant literature for systematic reviews in education

Systematic literature reviews in educational research have become a popular research method. A key point hereby is the choice of bibliographic databases to reach a maximum probability of finding all potentially relevant literature that deals with the research question analyzed in a systematic literature review. Guidelines and handbooks on review recommend proper databases and information sources for education, along with specific search strategies. However, in many disciplines, among them educational research, there is a lack of evidence on the relevance of databases that need to be considered to find relevant literature and lessen the risk of missing relevant publications. Educational research is an interdisciplinary field and has no core database. Instead, the field is covered by multiple disciplinary and multidisciplinary information sources that have either a national or international focus. In this article, we discuss the relevance of seven databases in systematic literature reviews in education, based on results of an empirical data analysis of three recently published reviews. To evaluate the relevance of a database, the relevant literature of those reviews served as the gold standard. Results indicate that discipline-specific databases outperform international multidisciplinary sources, and a combination of discipline-specific international and national sources is most efficient in finding a high proportion of relevant literature. The article discusses the relevance of the databases in relation to their coverage of relevant literature, while considering practical implications for researchers performing a systematic literature search. We, thus, present evidence for proper database choices for educational and discipline-related systematic literature reviews.

Correlations and Timeliness of COVID-19 Surveillance Data Sources and Indicators - United States, October 1, 2020-March 22, 2023.

When the U.S. COVID-19 public health emergency declaration expires on May 11, 2023, national reporting of certain categories of COVID-19 public health surveillance data will be transitioned to other data sources or will be discontinued; COVID-19 hospitalization data will be the only data source available at the county level (1). In anticipation of the transition, national COVID-19 surveillance data sources and indicators were evaluated for purposes of ongoing monitoring. The timeliness and correlations among surveillance indicators were analyzed to assess the usefulness of COVID-19-associated hospital admission rates as a primary indicator for monitoring COVID-19 trends, as well as the suitability of other replacement data sources. During April 2022-March 2023, COVID-19 hospital admission rates from the National Healthcare Safety Network (NHSN)† lagged 1 day behind case rates and 4 days behind percentages of positive test results and COVID-19 emergency department (ED) visits from the National Syndromic Surveillance Program (NSSP). In the same analysis, National Vital Statistics System (NVSS) trends in the percentage of deaths that were COVID-19-associated, which is tracked by date of death rather than by report date, were observable 13 days earlier than those from aggregate death count data, which will be discontinued (1). During October 2020-March 2023, strong correlations were observed between NVSS and aggregate death data (0.78) and between the percentage of positive SARS-CoV-2 test results from the National Respiratory and Enteric Viruses Surveillance System (NREVSS) and COVID-19 electronic laboratory reporting (CELR) (0.79), which will also be discontinued (1). Weekly COVID-19 Community Levels (CCLs) will be replaced with levels of COVID-19 hospital admission rates (low, medium, or high) which demonstrated >99% concordance by county during February 2022-March 2023. COVID-19-associated hospital admission levels are a suitable primary metric for monitoring COVID-19 trends, the percentage of COVID-19 deaths is a timely disease severity indicator, and the percentages of positive SARS-CoV-2 test results from NREVSS and ED visits serve as early indicators for COVID-19 monitoring. Collectively, these surveillance data sources and indicators can support monitoring of the impact of COVID-19 and related prevention and control strategies as ongoing public health priorities.

Effects of the Covid-19 Pandemic on Islamic and Conventional Financial Markets

The recent global Covid-19 pandemic is resentfully affecting global financial markets which including both Islamic and conventional stock markets. This study conducted an empirical examination to investigate the extent to which Covid-19 result on both Islamic and conventional financial markets, particularly the interconnections within the market activities. Data were collected from several national sources from 6 June 2020 to 27 September 2022, in two main periods. The study determined wavelet correlations among different variables to examine the effects of the pandemic. The findingsshow that the number of Covid-19 deaths was a significant determinant factor within the Islamic stock markets, contrary to conventional stock markets. Moreover, the results showed a positive link between the number of Covid-19 deaths and the Morgan Stanley capital International (MSCI) emerging market Asia Islamic index and the MSCI emerging Asia index. The link between exchange rates and crude oil in MSCI Gulf Corporation Council (GCC) countries combined was uncertain. However, this had a weak effect on Islamic indices and a strong effect on conventional indices. These findings contribute to assisting both investors and the market in optimising investment and market strategies.

Jewish population trajectories between the Jordan River and the Mediterranean Sea

ABSTRACT This article re-examines Jewish population in what is now Israel using historical estimates from Ottoman, Mandatory British and United Nations sources and recent data from the Israeli census bureau. A logistic model generates backward extrapolations and forward projections. The model quantifies three waves of Jewish immigration totalling about 3.5 million. Subtracting immigrant data from total population numbers gives the main empirical trajectory for non-immigrant native-born population. A multi-logistic model combining migrant and native populations projects a Jewish population of about 10 million in 2050, a level low in the range of estimates made by others.

Cost-effectiveness of the tubeless automated insulin delivery system vs standard of care in the management of type 1 diabetes in the United States.

BACKGROUND: A tubeless, on-body automated insulin delivery (AID) system (Omnipod 5 Automated Insulin Delivery System) demonstrated improved glycated hemoglobin A1c levels and increased time in range (70 mg/dL to 180 mg/dL) for both adults and children with type 1 diabetes in a 13-week multicenter, single-arm study. OBJECTIVE: To assess the cost-effectiveness of the tubeless AID system compared with standard of care (SoC) in the management of type 1 diabetes (T1D) in the United States. METHODS: Cost-effectiveness analyses were conducted from a US payer's perspective, using the IQVIA Core Diabetes Model (version 9.5), with a time horizon of 60 years and an annual discount of 3.0% on both costs and effects. Simulated patients received either tubeless AID or SoC, the latter being defined as either continuous subcutaneous insulin infusion (86% of patients) or multiple daily injections. Two cohorts (children: <18 years; adults: ≥18 years) of patients with T1D and 2 thresholds for nonsevere hypoglycemia (nonsevere hypoglycemia event [NSHE] <54 mg/dL and <70 mg/dL) were considered. Baseline cohort characteristics and treatment effects of different risk factors for tubeless AID were sourced from the clinical trial. Utilities and cost of diabetes-related complications were obtained from published sources. Treatment costs were derived from US national database sources. Scenario analyses and probabilistic sensitivity analyses were performed to test the robustness of the results. RESULTS: Treating children with T1D with tubeless AID, considering an NSHE threshold of less than 54 mg/dL, brings incremental life-years (1.375) and quality-adjusted life-years (QALYs) (1.521) at an incremental cost of $15,099 compared with SoC, resulting in an incremental cost-effectiveness ratio of $9,927 per QALY gained. Similar results were obtained for adults with T1D assuming an NSHE threshold of less than 54 mg/dL (incremental cost-effectiveness ratio = $10,310 per QALY gained). Furthermore, tubeless AID is a dominant treatment option for children and adults with T1D assuming an NSHE threshold of less than 70 mg/dL compared with SoC. The probabilistic sensitivity analyses results showed that compared with SoC, in both children and adults with T1D, tubeless AID was cost-effective in more than 90% of simulations, assuming a willingness-to-pay threshold of $100,000 per QALY gained. The key drivers of the model were the cost of ketoacidosis, duration of treatment effect, threshold of NSHE, and definition of severe hypoglycemia. CONCLUSIONS: The current analyses suggest that the tubeless AID system can be considered a cost-effective treatment compared with SoC in people with T1D from a US payer's perspective. DISCLOSURES: This research was funded by Insulet. Mr Hopley, Ms Boyd, and Mr Swift are full-time Insulet employees and own stock in Insulet Corporation. IQVIA, the employer of Ms Ramos and Dr Lamotte, received consulting fees for this work. Dr Biskupiak is receiving research support and consulting fees from Insulet. Dr Brixner has received consulting fees from Insulet. The University of Utah has received research funding from Insulet. Dr Levy is a consultant with Dexcom and Eli Lilly and has received grant/research support from Insulet, Tandem, Dexcom, and Abbott Diabetes. Dr Forlenza conducted research sponsored by Medtronic, Dexcom, Abbott, Tandem, Insulet, Beta Bionics, and Lilly. He has been speaker/consultant/advisory board member for Medtronic, Dexcom, Abbott, Tandem, Insulet, Beta Bionics, and Lilly.

Remembering Herbert Gutman's Work, Culture, and Society Fifty Years On

Remembering Herbert Gutman's <i>Work, Culture, and Society</i> Fifty Years On

Human Capital Basic Approach: Analysis Recruitment, Employee Retention Program, Leadership Development, System Reward, and Talent Management

The purpose of this study is to look at the effectiveness of the human capital department in managing employees to achieve company goals, this study uses a literature review from various national and international journal sources, and the novelty of this study is the formation of a new framework model that previously did not exist, the results of a review of various significant articles. This study does not use respondents or data processing as analysis, this study only concludes previous research for further research. In the future, the variables in this scientific article can be used to advance research using research methods, references, or objects used

Who are the future farmers? Media representations of youth in agriculture, food security and ‘modern’ farming in Indonesia

In Indonesia, state and non‐state actors frame youth attrition from agriculture as a food security concern and propose policy solutions focused on ‘modern’ farming techniques. Using a critical framing analysis of five national Indonesian news media sources from 2010 to 2020, we examine how government, development and private sector actors portray youth in agriculture, and the underlying assumptions that inform related policy and development agendas. Our analysis reveals contrasting portrayals of youth in agriculture. Youth are often depicted as averse to farming, while also being innovative adopters of modern farming techniques, equipment, and digital technologies. We argue that media frames reflect and reinforce the dominant discourses of state and non‐state actors, which have a productivist orientation, proposing technical, capital‐intensive agricultural solutions to food insecurity and related issues. News media pays comparatively less attention to structural barriers to youth entry and success in agriculture, such as limited access to land and finance and unfavourable terms of trade.

Health-Related Data Sources Accessible to Health Researchers From the US Government: Mapping Review

Big data from large, government-sponsored surveys and data sets offers researchers opportunities to conduct population-based studies of important health issues in the United States, as well as develop preliminary data to support proposed future work. Yet, navigating these national data sources is challenging. Despite the widespread availability of national data, there is little guidance for researchers on how to access and evaluate the use of these resources. Our aim was to identify and summarize a comprehensive list of federally sponsored, health- and health care-related data sources that are accessible in the public domain in order to facilitate their use by researchers. We conducted a systematic mapping review of government sources of health-related data on US populations and with active or recent (previous 10 years) data collection. The key measures were government sponsor, overview and purpose of data, population of interest, sampling design, sample size, data collection methodology, type and description of data, and cost to obtain data. Convergent synthesis was used to aggregate findings. Among 106 unique data sources, 57 met the inclusion criteria. Data sources were classified as survey or assessment data (n=30, 53%), trends data (n=27, 47%), summative processed data (n=27, 47%), primary registry data (n=17, 30%), and evaluative data (n=11, 19%). Most (n=39, 68%) served more than 1 purpose. The population of interest included individuals/patients (n=40, 70%), providers (n=15, 26%), and health care sites and systems (n=14, 25%). The sources collected data on demographic (n=44, 77%) and clinical information (n=35, 61%), health behaviors (n=24, 42%), provider or practice characteristics (n=22, 39%), health care costs (n=17, 30%), and laboratory tests (n=8, 14%). Most (n=43, 75%) offered free data sets. A broad scope of national health data is accessible to researchers. These data provide insights into important health issues and the nation's health care system while eliminating the burden of primary data collection. Data standardization and uniformity were uncommon across government entities, highlighting a need to improve data consistency. Secondary analyses of national data are a feasible, cost-efficient means to address national health concerns.

What Changes Have Occurred in Opioid Prescriptions and the Prescribers of Opioids Before TKA and THA? A Large National Registry Study.

What Changes Have Occurred in Opioid Prescriptions and the Prescribers of Opioids Before TKA and THA? A Large National Registry Study.

Data source profile reporting by studies that use routinely collected health data to explore the effects of drug treatment

BackgroundRoutinely collected health data (RCD) are important resource for exploring drug treatment effects. Adequate reporting of data source profiles may increase the credibility of evidence generated from these data. This study conducted a systematic literature review to evaluate the reporting characteristics of databases used by RCD studies to explore the effects of drug treatment.MethodsObservational studies published in 2018 that used RCD to explore the effects of drug treatment were identified by searching PubMed. We categorized eligible reports into two groups by journal impact factor (IF), including the top 5 general medical journals (NEJM, Lancet, JAMA, BMJ and JAMA Internal Medicine) and the other journals. The reporting characteristics of the databases used were described and compared between the two groups and between studies citing and not citing database references.ResultsA total of 222 studies were included, of which 53 (23.9%) reported that they applied data linkage, 202 (91.0%) reported the type of database, and 211 (95.0%) reported the coverage of the data source. Only 81 (36.5%) studies reported the timeframe of the database. Studies in high-impact journals were more likely to report that they applied data linkage (65.1% vs. 20.2%) and used electronic medical records (EMR) (73.7% vs. 30.0%) and national data sources (77.8% vs. 51.3%) than those published in other medical journals. There were 137/222 (61.7%) cited database references. Studies with database-specific citations had better reporting of the data sources and were more likely to publish in high-impact journals than those without (mean IF, 6.08 vs. 4.09).ConclusionsSome deficits were found in the reporting quality of databases in studies that used RCD to explore the effects of drug treatment. Studies citing database-specific references may provide detailed information regarding data source characteristics. The adoption of reporting guidelines and education on their use is urgently needed to promote transparency by research groups.

National Data and the Applicability to Understanding Rural and Remote Substance Use.

Responding to increases in overdose, addiction, and substance misuse, local public health experts need accurate data to plan and implement evidence-based prevention and treatment programs. In many countries, national data are the tool most readily available for these efforts. In the United States, the National Study on Drug Use and Health and the Treatment Episode Data Set are data sources used by states to determine the extent of addiction. This project sought to determine if these national data sources are applicable for local use in addiction prevention and program planning. NSDUH prevalence estimates from 2015 to 2019 were applied to the state population to determine the number of persons estimated to be substance users. The prevalence estimates were compared over time with the population data and substance use treatment admissions to assess the covariance and population change as an indicator of efficacy. The primary drivers of fatal overdose in Alaska are fentanyl, heroin, and methamphetamine. Fentanyl use was not assessed in either dataset. When applying the estimated use prevalence to the population, heroin users varied annually by 1777 persons and methamphetamine varied up to 2143 persons. These observed variances did not correspond with state population changes nor any trend in the persons seeking treatment for these substances. Our analyses do not support the use of NSDUH data for planning in rural and remote areas. The methods used in NSDUH data collection exclude ~ 20% of the state population, mostly Native persons, based on location and language. The annual prevalence estimates applied to the population did not correspond with changes in population nor changes in treatment. Fentanyl, which causes the most overdoses in Alaska and is of primary concern locally, was not assessed.

Cost-Effectiveness of Blinatumomab in Pediatric Patients with High-Risk First-Relapse B-Cell Precursor Acute Lymphoblastic Leukemia in France.

Based on the results of the phase III randomized 20120215 trial, the European Medicines Agency granted the approval of blinatumomab for the treatment of pediatric patients with high-risk first-relapsed Philadelphia chromosome-negative B-cell precursor acute lymphoblastic leukemia (ALL). In France, blinatumomab received reimbursement for this indication in May 2022. This analysis assessed the cost effectiveness of blinatumomab compared with high-risk consolidation chemotherapy (HC3) in this indication from a French healthcare and societal perspective. A partitioned survival model with three health states (event-free, post-event and death) was developed to estimate life-years (LYs), quality-adjusted life-years (QALYs) and costs over a lifetime horizon. Patients who were alive after 5 years were considered to be cured. An excess mortality rate was applied to capture the late effects of cancer therapy. Utility values were based on the TOWER trial using French tariffs, and cost input data were identified from French national public health sources. The model was validated by clinical experts. Treatment with blinatumomab over HC3 was estimated to provide gains of 8.39 LYs and 7.16 QALYs. Total healthcare costs for blinatumomab and HC3 were estimated to be €154,326 and €102,028, respectively, resulting in an increment of €52,298. The incremental cost-effectiveness ratio was estimated to be €7308 per QALY gained from a healthcare perspective. Results were robust to sensitivity analyses, including analysis from the societal perspective. Blinatumomab administered as part of consolidation therapy in pediatric patients with high-risk first-relapsed ALL is cost effective compared with HC3 from the French healthcare and societal perspective.

Characterization of an obese population: a retrospective longitudinal study from real-world data in northern Portugal

BackgroundObesity is a serious and largely preventable global health problem. Obesity-related electronic health records can be a useful resource to identify and address obesity. The analysis of real-world data from T82-coded (International Classification of Primary Care coding, for obesity) primary care individuals can be an excellent national source of data on obesity’s prevalence, characteristics, and impact on the National Health Service.MethodsRetrospective longitudinal study, based on a database of electronic medical records, from the Regional Health Administration of northern Portugal. The study objectives were to determine the prevalence of obesity and to characterize an adult obese population in northern Portugal from a bio-demographic point of view along with profiles of comorbidities and the use of health resources. This study used a database of 266,872 patients in December 2019 and screened for diagnostic code T82 from the International Classification of Primary Care.ResultsThe prevalence of obesity was 10.2% and the highest prevalence of obesity was in the 65–74 age group (16.1%). The most prevalent morbidities in patients with obesity as coded through ICPC-2 were K86 (uncomplicated hypertension), T90 (non-insulin-dependent diabetes), and K87 (complicated hypertension). Descriptive information showed that T82 subjects used more consultations, medications, and diagnostic tests than non-T82 subjects.ConclusionsRoutine recording of weight and height deserves special attention to allow obesity recognition at an early stage and move on to the appropriate intervention. Future work is necessary to automate the codification of obesity for subjects under 18 years of age, to raise awareness and anticipate the prevention of problems associated with obesity.Practical strategies need to be implemented, such as the creation of a specific program consultation with truly targeted approaches to obesity.

Chatbots at the service of government platforms

Aim: Within government activities, we have seen a marked digitalisation process in the last few years, both at domestic and international level. In this environment, human activity is naturally replaced by software solutions, and this is true for the governmental interaction with clients through government platforms. The aim of this study is to explore the conditions for the use of chatbot communication forms in public administrations, by examining the case where a government platform is used for the administrative procedures. The study also aims to explore and systematise the impact of these solutions on the transparency of the government platform and the administrative procedures carried out through it.Methodology: Critically analyse national and European legal sources of the subject, as well as implemented and planned practical solutions, in order to formulate a set of requirements and recommendations.Findings: The set of requirements for administrative procedures identifies a number of requirements that can be interpreted in the context of the use of chatbots as a communication method. These can also be interpreted in terms of legal compliance, and are not just recommendations or good practices. The impact of a software solution on transparency is twofold: on the one hand, it can greatly increase the transparency of the platform and the process, due to its speed and interactivity, and on the other hand, it can reduce it, depending on the degree of IT sophistication.Value: The most important new knowledge of the study, which can be interpreted in scientific terms, is that it defines the administrative requirements for chatbots as software solutions based on artificial intelligence, when they are used for the administration and communication of administrative procedure via government platforms. An important new concept of the study is the establishment of the equivalence principle, which applies when the human administrator’s contact and information tasks are replaced by a software solution on the platform in their entirety, without any choice.

Multisystem Inflammatory Syndrome in New Zealand Children.

New Zealand (NZ) initially adopted an elimination approach to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Pre-Omicron variant, the NZ pediatric population was immunologically naïve to SARS-CoV-2. This study, utilizing national data sources, describes the NZ incidence of multisystem inflammatory syndrome in children (MIS-C) following infection with the Omicron variant. MIS-C incidence was 1.03 of 100,000 age-specific population and 0.04 of 1000 recorded SARS-CoV-2 infections.

A systems science approach to identifying data gaps in national data sources on adolescent suicidal ideation and suicide attempt in the United States

BackgroundSuicide is currently the second leading cause of death among adolescents ages 10–14, and third leading cause of death among adolescents ages 15–19 in the United States (U.S). Although we have numerous U.S. based surveillance systems and survey data sources, the coverage offered by these data with regard to the complexity of youth suicide had yet to be examined. The recent release of a comprehensive systems map for adolescent suicide provides an opportunity to contrast the content of surveillance systems and surveys with the mechanisms listed in the map.ObjectiveTo inform existing data collection efforts and advance future research on the risk and protective factors relevant to adolescent suicide.MethodsWe examined data from U.S. based surveillance systems and nationally-representative surveys that included (1) observations for an adolescent population and (2) questions or indicators in the data that identified suicidal ideation or suicide attempt. Using thematic analysis, we evaluated the codebooks and data dictionaries for each source to match questions or indicators to suicide-related risk and protective factors identified through a recently published suicide systems map. We used descriptive analysis to summarize where data were available or missing and categorized data gaps by social-ecological level.ResultsApproximately 1-of-5 of the suicide-related risk and protective factors identified in the systems map had no supporting data, in any of the considered data sources. All sources cover less than half the factors, except the Adolescent Brain Cognitive Development Study (ABCD), which covers nearly 70% of factors.ConclusionsExamining gaps in suicide research can help focus future data collection efforts in suicide prevention. Our analysis precisely identified where data is missing and also revealed that missing data affects some aspects of suicide research (e.g., distal factors at the community and societal level) more than others (e.g., proximal factors about individual characteristics). In sum, our analysis highlights limitations in current suicide-related data availability and provides new opportunities to identify and expand current data collection efforts.

Analisis Faktor yang Mempengaruhi Minat Gen Z dalam Berinvestasi di Pasar Modal (Studi Kasus Mahasiswa Fakultas Ekonomi dan Bisnis di Solo Raya)

The readiness of the younger generation to tackle financial challenges is a crucial thing that must be taken into account in order to maintain a good living standard in the future.The right saving method is an important aspect of managing and achieving financial targets, one of which is in the form of investment in the capital market. The younger generation is a potential target for the financial (investment) industry sector because they have sufficient knowledge of investment products and have a long saving period before reaching unproductive age. There are several factors that can encourage the younger generation to invest in the capital market. This study aims to analyze the factors of investment knowledge, investment benefits, financial literacy and return expectations which can affect one's investment interest, especially the younger generation such as university students. This study uses primary data by distributing questionnaires to respondents, and nalyzeda using linear regression with the SPSS 25 software. The results of the study indicate that investment knowledge and expected return influences investment interest, especially among students who are currently studying in the Solo Raya area.The government and related institutions need to increase the participation of young people in various investment alternatives, so as to increase national development funding sources.

A IMPORTÂNCIA DA PRESENÇA BRASILEIRA NO CONTINENTE ANTÁRTICO

The present work aims to present a study on the reasons that justify the Brazilian presence in the Antarctic continent. For this, a theoretical research of authors of International Law was used, as well as information and interpretations from national and international sources. To facilitate the study of these reasons, it was decided to divide them into three levels of analysis, namely: economic, scientificenvironmental and geopolitical. Throughout the work, we sought to explain each of these axes. As for the economic motivation, Brazil's interests in relation to the continent's resources such as fish, oil and minerals will be explained. Regarding the scientific-environmental scope, it will be verified if the Brazilian environmental and scientific policy is convergent with the goals of conservation of Antarctica, foreseen in international conventions. In the geopolitical area, the Brazilian strategic interests for the Antarctic continent will be analyzed, in view of its geographic location and present and future importance. By cataloging these reasons and using the deductive method, the conclusions of the analysis will be presented, answering the problem initially exposed.