BackgroundClinical opportunities can be challenging for nursing students to obtain with regards to the perioperative setting. In this paper, we describe nursing students’ perceptions of participating in perioperative simulation-based experiences using a multi-station format. The purpose of this study was to better understand if this format enhanced undergraduate nursing student learning of perioperative content. MethodA cross-sectional descriptive study using the National League for Nursing (NLN) Simulation Design Scale examined the perceptions of 53 traditional and 82 accelerated undergraduate nursing students participating in a combination of intentional high and low-fidelity multi-station perioperative simulation-based experiences. ResultsParticipants perceived the multi-station format to be beneficial to their learning of perioperative content. Mean scores for both groups were between 4 and 5 on the 5-point Likert scale. ConclusionThe findings support the intentional multi-station perioperative simulation format as an effective simulation-based learning experience.