AbstractBackground: Endoscopic septoplasty is an attractive alternative to the traditional septoplasty. It ensures the mini-mum dissection of the tissue with less postoperative compli-cations.Aim of Work: The aim of this work was to compare the efficacy of the conventional and the endoscopic assisted septoplasty in the management of cases with severe septal deviation.Patients and Methods: 60 patients with severe symptomatic deviated nasal septum, presented to the Otorhinolaryngology outpatient clinic at Tanta University Hospitals divided into two equal groups: Group A included 30 patients underwent endoscopic septoplasty and group B included 30 patients underwent traditional septoplasty. All participants evaluated regarding the nasal obstruction improvement, and the degree of the improvement, the accompanying symptoms and any complications.Results: There was a significant difference between both groups in duration of surgery, the intraoperative blood loss. In this study, the difference of the endoscopic group as compared to the conventional group was statistically insignif-icant regarding either early post-operative complications or in nasal synechiae development, pain, septal hematoma, septal perforation, or CSF leakage or in the intraoperative flap. The pre-operative nose score comparative evaluation revealed that all patients of both groups reported a severe problem in all parameters (nasal congestion and stuffiness, nasal blockage or obstruction, trouble breath in through the nose, trouble sleeping, and inability to get enough air through the nose during exercise or exertion. No statistically significant differ-ences were detected between both groups.Conclusion: We concluded that, endoscopic septoplasty is superior to traditional septoplasty with better result and less complication.