Nowadays quality education for the younger generation is the key to the development of the state. This paper proves that including the separate issues of the basics of nanotechnology in physics lessons will update the content of learning physics and will be the basis for the training of qualified personnel. The purpose of the article is to reveal the methodological specifics of teaching students the basics of nanotechnology in physics lessons in the 10th form. The analysis of the textbooks recommended by the Ministry of Education and Science of Ukraine on physics for the 10th forms has been carried out. The article is proposed to include the separate issues of the basics of nanotechnology in the sections «Mechanics» and «Molecular physics and thermodynamics». The methodical recommendations for teaching of the separate issues of the basics of nanotechnology have been developed. The content of the article is a logical continuation of the previously defined methodological specifics of teaching pupils the basics of nanotechnology in the course of physics for the 7th, 8th and 9th forms, which will contribute to the formation of a comprehensive view of nanotechnology among students and will ensure continuation in studying the basics of nanotechnology. Formation of subject nanotechnological competence has to become a result of learning separate issues of the basics of nanotechnology in physics lessons. The article focuses on the use of non-traditional teaching methods (methods of problem-based learning, interactive methods, project method) when studying relevant issues of nanotechnological topic. We have drawn a conclusion that the including the separate issues of the basics of nanotechnology in school course of physics will contribute to the formation of high school students' ideas about nanotechnology and will be important step towards the training of specialists capable of developing this new field of science and technology for the economic and technological growth of our country. Key words: nanotechnology education, school course of physics, methodological specifics of teaching pupils the basics of nanotechnology.