Nanofibrous Membranes Research Articles

Arsenic removal from contaminated water using adsorptive electrospun nanofibrous membrane of polyacrylonitrile/organoclay

AbstractAdsorptive nanofiber electrospun membranes (ANEMs) show promise for heavy metal removal, particularly in dilute solutions. Nanofibrous polyacrylonitrile (PAN) membranes incorporating Cloisite 20A (C20) organoclay were fabricated via electrospinning for As(V) removal. The impact of C20 on structural properties and As(V) removal efficiency of the nanofiber membranes was investigated. The results indicated that the PAN‐C20 membranes morphology was uniform, with fiber diameters mostly falling within the 100–300 nm range. Incorporation of C20, especially in an exfoliated structure, led to increased hydrophilicity, mechanical strength, and roughness of the membranes. Batch adsorption results revealed that the adding C20 up to 1.5 wt.% significantly enhanced adsorption capacity due to the higher concentration and proper C20 dispersion. Dynamic filtration showed that the PAN‐C20(1.0) membrane achieved over 90% As(V) removal efficiency for 960 min and demonstrated excellent regeneration ability.Highlights Cloisite 20A organoclay was incorporated into PAN by electrospinning to prepare adsorptive membrane. Adsorptive membranes were used for As(V) removal from water. Type of Cloisite 20A dispersion in PAN in dynamic filtration was more important than in static adsorption PAN‐C20‐1.0 with exfoliated structure showed higher removal efficiency than PAN‐C20‐1.0 with intercalated structure. PAN‐C20‐1.0 membrane was usable for multiple adsorption–desorption cycles.

Antimicrobial and antioxidative electrospun cellulose acetate-essential oils nanofibrous membranes for active food packaging to extend the shelf life of perishable fruits

Food preservation is critical to meeting the growing demand for fresh foods. We construct novel active packaging using active chemicals to extend the shelf life of fresh fruit and vegetables. In our study, we harnessed electrospinning technology to manufacture cellulose acetate nanofibers (CANFs) using natural, highly volatile cinnamon bark oil (CNO) and clove bud oil (CBO). The CNO and CBO loaded electrospun fibers were characterized and applied as active packaging membrane to evaluate the impact on shelf life of fresh grapes and tomatoes. Scanning electron microscopy (SEM), fourier-transform infrared spectroscopy (FT-IR), and gas chromatography–mass spectrometry (GC–MS) analysis indicated a uniform volatile component distribution, average fiber diameters, regulated release kinetics, and substantial antioxidant, and antibacterial activities. The use of 50 % w/w CNO and CBO-loaded CANFs as an active food packaging membrane for a shelf-life study of fresh grapes and tomatoes at 4 °C confirmed the microbiological safety of consumption for 40 days compared to 15 days in control samples, with a lesser reduction in physiochemical properties despite sensory evaluation revealing a shelf-life extension until 30 days.The efficacy and potential benefits of sustainable and effective packaging strategies are highlighted in this study, making it a promising alternative for preserving perishable tomatoes and grapes.

Nanofibers Membrane Loaded with Titanium Oxide and Rifampicin as Controlled Drug Delivery System for Wound Dressing Applications

Nanofibers Membrane Loaded with Titanium Oxide and Rifampicin as Controlled Drug Delivery System for Wound Dressing Applications

Enhancing performance and durability of PVDF-ceramic composite membranes in microbial fuel cells using natural rhamnolipids

Ceramic membranes are widely used in microbial fuel cells (MFCs) owing to their cost-effectiveness and availability. However, these membranes often face challenges such as biofouling and negative mass-transfer effects. This study explored the use of a polymer layer to mitigate these issues, focusing on a polyvinylidene fluoride (PVDF) nanofibre membrane with various surface modifications. The modifications included alkaline treatment (PVDF-OH), rhamnolipids treatment (PVDF/BS), and a combination of both (PVDF-OH/BS). The ceramic membrane integrated with PVDF-OH/BS achieved the highest power density of 13.8 W m−3, which was 38 % higher than that of the unmodified ceramic membrane. Additionally, during the long-term study (days 90–101), the Ceramic + PVDF-OH/BS maintained a 64 % higher power performance compared to the unmodified ceramic membrane, indicating superior antifouling properties. Electrochemical and surface characterisation revealed that rhamnolipid-modified PVDF nanofibers enhanced fouling resistance. The findings demonstrate that natural biosurfactants which can be produced in situ within MFCs, can form a protective layer over membranes and significantly enhance their long-term power performance. This study represents the first instance of using natural microbial biosurfactants to improve membrane efficiency in a bioelectrochemical system.

Enhanced self-driven flexible piezoelectric nanogenerator sensor based on NaNbO3/P(VDF-TrFE) films for security applications

The self-driven flexible piezoelectric sensor has wide application prospects in areas such as health monitoring, human-machine interaction, and warning detection due to its advantages of non-toxicity and high sensitivity. In this study, a composite film of poly(vinylidene fluoride-trifluoroethylene) [P(VDF-TrFE)] doped with NaNbO3 (NN) was prepared by electrospinning. The highly oriented NN particles promote the formation of P(VDF-TrFE) β phase, reaching a maximum β phase content of 91%. Under mechanical motion at a frequency of approximately 3 Hz, the piezoelectric nanogenerator (PENG) fabricated from the nanofiber membrane achieved a maximum piezoelectric output of 17.3 V and 12 V in the transverse and longitudinal piezoelectric responses, respectively. With an external load of 100 MΩ, the PENG obtained a maximum power density of 0.67 μW/cm². Additionally, the PENG sensor exhibited sensitivity to various human activities and demonstrated high sensitivity and rapid response in monitoring the status of the proposed door lock opening/closing, highlighting its enormous potential in security monitoring applications.

Long-term and high-efficiency capture of Escherichia coli using cellulose acetate nanofiber membrane functionalized with reactive 19 dye and polyhexamethylene biguanide

Cellulose acetate (CA) nanofibers have been popularly applied in various biomedical and textile products. In this work, a textile azo-dye Reactive Green 19 (RG19) was selected to be chemically coupled to the CA nanofiber membrane to form dyed CA nanofiber membrane (namely CA-RG19) and then poly(hexamethylene biguanide) (PHMB) as an antibacterial reagent was physically attached to the dyed CA nanofiber membrane, forming CA-RG19-PHMB nanofiber membrane. The nanofiber membranes were evaluated for their physical and mechanical properties, including functional group analysis, morphological characterization, and thermal stability assessment. To investigate the antibacterial properties of the nanofiber membrane, various concentrations of RG19 dye and PHMB were tested to evaluate the antibacterial efficiency (AE) against Escherichia coli of the membranes. It was found that the CA-RG19-PHMB nanofiber membrane exhibited an AE value of approximately 100 %, with the immobilization concentrations of RG19 dye and PHMB being 373.46 mg/g and 0.333 mg/g, respectively. The CA-RG19-PHMB nanofiber membrane showed 100 % antibacterial efficacy after 10 min against E. coli cells. Furthermore, the storage stability of the CA-RG19-PHMB nanofiber membrane remained at approximately 100 % of its initial antibacterial efficacy after 60 days, and it exhibited excellent antibacterial efficacy after five cycles.

Production of γ-aminobutyric acid by immobilization of two Yarrowia lipolytica glutamate decarboxylases on electrospun nanofibrous membrane

This study harnesses glutamate decarboxylase (GAD) from Yarrowia lipolytica to improve the biosynthesis of γ-aminobutyric acid (GABA), focusing on boosting the enzyme's catalytic efficiency and stability by immobilizing it on nanofibrous membranes. Through recombinant DNA techniques, two GAD genes, YlGAD1 and YlGAD2, were cloned from Yarrowia lipolytica and then expressed in Escherichia coli. Compared to their soluble forms, the immobilized enzymes exhibited significant improvements in thermal and pH stability and increased resistance to chemical denaturants. The immobilization notably enhanced substrate affinity, as evidenced by reduced Km values and increased kcat values, indicating heightened catalytic efficiency. Additionally, the immobilized YlGAD1 and YlGAD2 enzymes showed substantial reusability, maintaining 50% and 40% of their activity, respectively, after six consecutive cycles. These results underscore the feasibility of employing immobilized YlGAD enzymes for cost-effective and environmentally sustainable GABA production. This investigation not only affirms the utility of YlGADs in GABA synthesis but also underscores the advantages of enzyme immobilization in industrial settings, paving the way for scalable biotechnological processes.

Real-Time Wireless Sensing of Cardiomyocyte Contractility by Integrating Magnetic Microbeam and Oriented Nanofibers.

In vitro cardiomyocyte mechano-sensing platform is crucial for evaluating the mechanical performance of cardiac tissues and will be an indispensable tool for application in drug discovery and disease mechanism study. Magnetic sensing offers significant advantages in real-time, in situ wireless monitoring and resistance to ion interference. However, due to the mismatch between the stiffness of traditional rigid magnetic material and myocardial tissue, sensitivity is insufficient and it is difficult to achieve cell structure induction and three-dimensional cultivation. Herein, a magnetic sensing platform that integrates a neodymium-iron-boron/polydimethylsiloxane (NdFeB/PDMS) flexible microbeam with suspended and ordered polycaprolactone (PCL) nanofiber membranes was developed, providing a three-dimensional anisotropic culture environment for cardiomyocyte growth and simultaneously realizing in situ wireless contractility monitoring. The as-prepared sensor presented an ultrahigh sensitivity of 442.2 μV/μm and a deflection resolution of 2 μm. By continuously monitoring the cardiomyocyte growth status and drug stimulation feedback, we verified the capability of the platform to capture dynamic changes in cardiomyocyte contractility. This platform provides a perspective tool for evaluating cardiomyocyte maturity and drug performance.

MXene-coated piezoelectric poly-L-lactic acid membrane accelerates wound healing by biomimicking low-voltage electrical pulses

Electrical stimulation therapy is effective in promoting wound healing by rescuing the decreased endogenous electrical field, where self-powered and miniaturized devices such as nanogenerators become the emerging trends. While high-voltage and unidirectional electric field may pose thermal effect and damage to the skin, nanogenerators with lower voltages, pulsed or bidirectional currents, and less invasive electrodes are preferred. Herein, we construct a polydopamine (PDA)-modified poly-L-lactic acid (PLLA) /MXene (PDMP/MXene) nanofibrous composite membrane that generates piezoelectric voltages matching the transepithelial potential (TEP) to accelerate wound healing. PDA coating not only enhances the piezoelectricity of PLLA by dipole attraction and alignment, but also increases its hydrophilicity and facilitates subsequent MXene adhesion for electrical conductivity and stability in physiological environment. When applied as wound dressings in mice, the PDMP/MXene membranes act as a nanogenerators with reduced internal resistances and satisfactory piezoelectric performances that resemble bioelectric potentials (~10 mV) responding to physical activities. The membrane significantly accelerates wound closure by facilitating fibroblast migration, collagen deposition and angiogenesis, and suppressing the expression of inflammatory responses. This piezoelectric fibrous membrane therefore provides a convenient solution for speeding up wound healing by sustained low voltage mimicking bioelectricity, better cell affinity.

Fully Integrated Recognition and Enrichment Electrospray Ionization Source for High-Sensitivity Mass Spectrometry Determination of Bioamine.

The development of a highly specific recognition electrospray ionization source presents a major challenge for achieving rapid ambient mass spectrometry (AMS) detection of trace harmful substances in complex samples. In this study, we constructed a molecular imprinting nanofiber electrospinning membrane-coated steel substrate (MINMCS) based on the electrospinning strategy. This was designed as a highly specific recognition and enrichment electrospray ionization source module for AMS, where the molecular imprinting nanofiber membrane served as an excellent extraction and enrichment layer. The prepared ionization source demonstrated a sufficient loading capacity for three bioamines (BAs): histamine (HIS), tyramine (TYR), and tryptamine (TRY). With simplified sample pretreatment, this ionization source exhibited sensitivity comparable to that of high performance liquid chromatography-mass spectrometry (HPLC-MS/MS). Moreover, the entire analysis process could be completed within 1 min with acceptable recoveries (83.21-101.80%). In brief, this study introduces a new integrated recognition and enrichment electrospray ionization source for the detection of harmful substances such as bioamines, showcasing significant commercial potential for the rapid detection of foodborne harmful compounds.

Cascade Hydroxyl Radical-Generating and Ferroptosis-Inducing Nanofiber System for the Therapy of Oral Squamous Cell Carcinoma.

Nanofiber (NF) membrane systems that can provide cascade catalytic reaction and ferroptosis induction were developed for oral cancer therapy. Glucose oxidase (GOx) and aminoferrocene (AF) were introduced into the NF system for glucose deprivation/H2O2 generation and OH radical generation, respectively. GOx offers starvation therapy and AF (including iron) provides chemodynamic therapy/ferroptosis for combating oral cancer. GOx (water-soluble) and AF (poorly water-soluble) molecules were successfully entrapped in the NF membrane via an electrospinning process. GOx and AF were incorporated into the polyvinyl alcohol (PVA)-based NF, resulting in PVA/GOx/AF NF with fast disintegration and immediate drug-release properties. In oral squamous cell carcinoma (YD-9 cells), the PVA/GOx/AF NF group exhibited higher cytotoxicity, antiproliferation potential, cellular ROS level, apoptosis induction, lipid ROS level, and malondialdehyde level compared to the other NF groups. The electrospun PVA/GOx/AF NF can be directly applied to oral cancer without causing pain, offering starvation/chemodynamic therapy and ferroptosis induction.

Emulsion electrospun epigallocatechin gallate-loaded silk fibroin/polycaprolactone nanofibrous membranes for enhancing guided bone regeneration

Guided bone regeneration (GBR) membranes play an important role in oral bone regeneration. However, enhancing their bone regeneration potential and antibacterial properties is crucial. Herein, silk fibroin (SF)/polycaprolactone (PCL) core-shell nanofibers loaded with epigallocatechin gallate (EGCG) were prepared using emulsion electrospinning. The nanofibrous membranes were characterized via scanning electron microscopy, transmission electron microscopy, Fourier transform infrared spectroscopy, thermogravimetric analysis, water contact angle (CA) measurement, mechanical properties testing, drug release kinetics, and 1,1-diphenyl-2-picryl-hydrazyl radical (DPPH) free radical scavenging assay. Mouse pre-osteoblast MC3T3-E1 cells were used to assess the biological characteristics, cytocompatibility, and osteogenic differentiation potential of the nanofibrous membrane. Additionally, the antibacterial properties againstStaphylococcus aureus (S. aureus)andEscherichia coli (E. coli)were evaluated. The nanofibers prepared by emulsion electrospinning exhibited a stable core-shell structure with a smooth and continuous surface. The tensile strength of the SF/PCL membrane loaded with EGCG was 3.88 ± 0.15 Mpa, the water CA was 50°, and the DPPH clearance rate at 24 h was 81.73% ± 0.07%. The EGCG release rate of membranes prepared by emulsion electrospinning was reduced by 12% within 72 h compared to that of membranes prepared via traditional electrospinning.In vitroexperiments indicate that the core-shell membranes loaded with EGCG demonstrated good cell compatibility and promoted adhesion, proliferation, and osteogenic differentiation of MC3T3-E1 cells. Furthermore, the EGCG-loaded membranes exhibited inhibitory effects onE. coliandS. aureus. These findings indicate that core-shell nanofibrous membranes encapsulated with EGCG prepared using emulsion electrospinning possess good antioxidant, osteogenic, and antibacterial properties, making them potential candidates for research in GBR materials.

Flexible ZIF-67@PVDF tree-like nanofiber membrane with high piezoelectric output for energy harvesting

Modern demands for efficient, environmentally friendly, and self-powered devices have led to growing interest in piezoelectric polymers in the scientific community. In this paper, a ZIF-67 functionalized polyvinylidene fluoride/ tetrabutylammonium hexafluorophosphate tree-like nanofiber membrane (ZIF-67@PVDF/TBAHP-TLNMs) was developed as piezoelectric nanogenerator for energy harvesting. The ZIF-67@PVDF/TBAHP-TLNMs was prepared by in-situ growth of ZIF-67 on the surface of PVDF TLNMs, which demonstrated remarkable energy harvesting capabilities. The results indicated that the β-phase content of the in-situ growth of ZIF-67 reached 86.94 %, augmented the fiber's rotation radius, and elevated the electromechanical conversion efficiency. Notably, the short circuit current reached 3.87 μA and the output voltage exceeded 9.78 V, which was 10.7 times and 5.9 times higher than the electrical signal output of pure PVDF nanofiber membrane, respectively. Furthermore, the ZIF-67@PVDF/TBAHP-TLNMs exhibited exceptional mechanical properties, with an elastic modulus as high as 1.13 GPa, outperforming other nanofiber membranes and catering to the diverse requirements of wearable devices. During a 500 s test cycle, its layered structure remained intact, without any discernible damage or interlayer separation of the nanofibers. At the same time, the device exhibited high electromechanical conversion efficiency and a sensitive sensing function, which made it have broad application prospects in human motion monitoring and intelligent wearable devices.

Development of superhydrophobic PVA/CNC nanofibrous membranes for enhanced oil-water separation

Effective oil–water separation is crucial for environmental purification and the remediation of oil pollution, yet current methods face limitations in efficiency, durability, and environmental impact. In this study, we aimed a green nanofibrous membrane with excellent oil–water separation efficiency, addressing the significant environmental challenge of separating oil from water in various states. For this purpose, polyvinyl alcohol (PVA)-based nanofibers were prepared by aqueous electrospinning. The mechanical strength of the nanofibers was reinforced by adding cellulose nanocrystals (CNCs). The surface of the nanofibers was modified with hexadecyltrimethoxysilane (HDTMS) to induce hydrophobicity, evidenced by the increase in contact angle from 44.41° to 133.19°, facilitating effective oil separation from various states, including dispersed, suspended, and emulsified states. The prepared PVA/CNC-HDTMS nanofiber showed 194 %, 539 %, and 407 % higher tensile strength, yield strength, and Young’s modulus than PVA nanofibers, respectively. The oil sorption capacity of the nanofibers varied widely from 17.01-113.76 g/g, which is strongly influenced by the viscosity and volatility of the oil species. The durability and reusability of the nanofibers were well maintained, even after being reused more than 10 times without morphological deterioration. In separating oil–water mixtures, the nanofibers maintained a high flux of 40,039 L/m2h and a separation efficiency of 99.2 % under pressurized conditions. Additionally, the nanofibers achieved a separation efficiency of 98.5 % in oil–water emulsion states.

Biobased Polybutyrolactam Nanofiber with Excellent Biodegradability and Cell Growth for Sustainable Healthcare Textiles.

The white pollution caused by unsustainable materials is a significant challenge around the globe. Here, a novel and fully biobased polybutyrolactam (PBY) nanofiber membrane was fabricated via the electrospinning method. As-spun PBY nanofiber membranes have good thermal stability, high porosity of up to 71.94%, and excellent wetting behavior. The biodegradability in soil, UV aging irradiation, and seawater was investigated. The PBY nanofiber membrane is almost completely degraded in the soil within 80 days, showing excellent degradability. More interestingly, γ-aminobutyric acid, as a healthcare agent with intrinsic hypotensive, tranquilizing, diuretic, and antidiabetic efficacy, can be detected in the degradation intermediates. In addition, the PBY nanofiber membrane also exhibits antibacterial ability against Escherichia coli. As a fully biomass-derived material, the PBY membrane has excellent biodegradable performance in various environments as well as negligible cytotoxicity and commendable cell proliferation. Our PBY nanofiber membrane shows great potential as biodegradable packaging and in vitro healthcare materials.

MOF-5 anchored polymer@carbon core–shell nanofibers for efficient removal of chlortetracycline from aqueous solution

Antibiotics excreted by human or animal may contain un-degradable residues, which form high concentration accumulation in water, leading to seriously harmful effects on the environment. Herein, MOF-5 anchored polymer@carbon core–shell nanofibers (MAPC) are fabricated via the electrospinning-hydrothermal synthesis and used for high efficiency removing chlortetracycline (CTC) from water. The anchored MOF-5 enhances the adsorption ability of hydrothermal carbon core–shell nanofibers. The MAPC nanofibers exhibit 395.87 mg/g of adsorption capacity for CTC removal process, which well fitted with Freundlich isotherm model and pseudo-second-order kinetic model. After nanofiber membrane filtering, the removal efficiency of CTC is nearly 100 % at the concentration of 5 mg/L. And the chemical oxygen demand (COD) concentration of CTC is reduced from 156.72 mg/L to 50.39 mg/L, that is below the pharmaceutical wastewater discharge standard. In addition, MAPC exhibits high flux and good regeneration performance. This work gives a typical strategy of feasible preparation of high efficiency MOFs anchored carbon-based nanofiber adsorbent towards the pharmaceutical wastewater treatment.

Ultrahigh absorption dominant EMI shielding polyimide composites with enhanced piezoelectric property

Piezoelectric sensors have been widely used in wearable electronic devices with improved integration, which is prone to cause electromagnetic interference (EMI) pollution and affects its operation stability. How to design the materials with integrated piezoelectric sensing and EMI shielding performance is of great significance. In this paper, the Fe3O4@PPy/PINF (FPN) composite film was prepared by depositing pyrrole (Py) on the surface of Fe3O4 nanoparticles and combining it with polyimide (PI) nanofibrous membrane via vacuum-assisted suction filtration. In addition, after encapsulation with a highly soluble fluorine-containing polyimide (FPI) resin, a structurally stable FPI-Fe3O4@PPy/PINF (PFPN) composite film was obtained. The prepared PFPN composites show excellent EMI shielding effectiveness (44.58 dB) through the secondary reflection and multiple absorption effects. Remarkably, the value of the absorption coefficient A can reach 0.74, showing outstanding absorption characteristics. In addition, PFPN composite film also shows unexpected piezoelectric properties with high sensitivity of S = 0.8, short response (25 ms) and recovery (45 ms) time. Its piezoelectric output can reach 4.2 V with stable cyclic output property (>15000 times). This kind of composite film with ultra-low reflection characteristics and favorable piezoelectricity presents a wide range of potential applications in the self-powered wearable electronic fields.

Preparation and Properties of Polyimide/Polysulfonamide/Polyethylene Glycol (PI/PSA/PEG) Hydrophobic Nanofibrous Membranes.

In this study, polyimide (PI) and polysulfonamide (PSA) were used as base materials, and polyethylene glycol (PEG) was added to successfully prepare PI/PSA/PEG nanofiber membranes through electrospinning technology. Subsequently, water etching was performed on the membranes, utilizing the water solubility of PEG to form the rough wrinkled structure, further enhancing the surface hydrophobicity. The experimental results showed that under the conditions of a spinning voltage of 10 kV, PI/PSA mass fraction of 15 wt.%, and PEG-to-PI/PSA mass ratio of 1/3, the obtained fiber membranes exhibit a uniform morphology (an average diameter of 0.73 µm) and excellent hydrophobicity (the initial water contact angle (WCA) reaching 130.4°). After PEG water etching, the surface of the PI/PSA/PEG hydrophobic membranes formed the rough wrinkled structure, which not only improved their mechanical properties but also further enhanced their hydrophobicity (the initial WCA increasing to 137.9°). Hence, fiber membranes are expected to have broad application prospects in fields such as waterproofing and moisture permeability.

Baicalein-modified chitosan nanofiber membranes with antioxidant and antibacterial activities for chronic wound healing

Diabetic foot ulcers, burns and many other trauma can lead to the formation of skin wounds, which often remain open for a long period of time, seriously affecting the quality of patient's life. Oxidative stress and infection are the main factors affecting the healing of chronic wounds, so it is important to develop dressings with dual antioxidant and antimicrobial properties for wound management. In this study, functionalized chitosan was synthesized by modifying chitosan with antioxidant baicalein to enhance the antimicrobial and antioxidant activities of chitosan. Then the obtained baicalein-modified chitosan was prepared into nanofibrous membranes by electrospinning. The membrane structures were characterized, and the antioxidant and antibacterial activities were evaluated by in vivo and in vitro experiments. The results showed that the prepared wound dressings had excellent antioxidant and antibacterial activities and significantly accelerated the wound process. This study provided a reference for the development of novel dressing materials to promote wound healing.

Interfacial Polarization Strategy to Electroactive Poly(lactic acid) Nanofibers for Humidity-Resistant Respiratory Protection and Machine Learning-Assisted Monitoring.

The advancement of intelligent and biodegradable respiratory protection equipment is pivotal in the realm of human health engineering. Despite significant progress, achieving a balance between efficient filtration and intelligent monitoring remains a great challenge, especially under conditions of high relative humidity (RH) and high airflow rate (AR). Herein, we proposed an interfacial stereocomplexation (ISC) strategy to facilitate intensive interfacial polarization for poly(lactic acid) (PLA) nanofibrous membranes, which were customized for machine learning-assisted respiratory diagnosis. Theoretical principles underlying the facilitated formation of the electroactive phase and aligned PLA chains were quantitatively depicted in the ISC-PLA nanofibers, contributing to the increased dielectric constant and surface potential (as high as 2.2 and 5.1 kV, respectively). Benefiting from the respiration-driven triboelectric mechanisms, the ISC-PLA demonstrated a high PM0.3 filtration efficiency of over 99% with an ultralow pressure drop (75 Pa), even in challenging circumstances (95 ± 5% RH, AR of 85 L/min). Furthermore, we implemented the ISC-PLA with multifunction respiratory monitoring (response time of 0.56 s and recovery time of 0.25 s) and wireless transmission technology, yielding a high recognition rate of 83% for personal breath states. This innovation has practical implications for health management and theoretical advancements in respiratory protection equipment.