Nanocomposite Microspheres Research Articles

Simple and facile preparation of tunable chitosan tubular nanocomposite microspheres for fast uranium(VI) removal from seawater

The seawater contains 4.5 billion tons of uranium(VI), which is quite enough to provide a continuous supply of infinite nuclear energy. However, it is a sudden need to develop adsorbents from abundant available source, easy collect property, large durability and high uranium(VI) adsorption capacity from seawater. In this work, a single-step process was developed for the preparation of chitosan (Cs) functionalized tubular carbon nanocomposite microspheres (CsFTnCM) for efficient uranium(VI) adsorption from seawater. The application of newly synthesized adsorbent for uranium(VI) removal from seawater is explored. Thus prepared adsorbent (CsFTnCM2) is found to adsorb 99.5% uranium(VI) from seawater. The CsFTnCM2 (Cs/FTn,1:1) comprising NH2 and COOH content approximately 0.61 mmol/g and 0.23 mmol/g, respectively. This kind of adsorbent possessed a uranium(VI) loading capacity of 0.660 (mg/g) from seawater. The adsorption kinetics not only dependent on the physical structure of the adsorbent but depends on the proportion of FTn in the Cs-matrix. However, the kinetics of uranium(VI) adsorption was increased by increasing the content of FTn up to a certain limit. The adsorption efficiency of uranium(VI) was not affected by the presence of coexisted ions, whose concentration is 1000 times greater than uranium(VI) in seawater. The desorption of uranium(VI) from the seawater exposed adsorbents were investigated and the results showed the uranium(VI) strip from the adsorbents found to be efficiently using Na2CO3.

Aminated chitosan/cellulose nanocomposite microspheres designed for efficient removal of low-concentration sulfamethoxazole from water

The ppt to ppb sulfamethoxazole (SMX) entering natural water bodies and possibly present in drinking water is not significantly removed and remain persistent and toxic by conventional adsorbents. Aminated chitosan/cellulose nanocomposite microspheres (ACNM) were prepared by in-situ solid phase grafting methods for low concentration of SMX removal. The physical and chemical properties of ACNM were characterized by SEM, FTIR and XRD etc. 10 mg L−1 SMX was used to simulate the low concentration of SMX in the aqueous phase, SMX adsorption on ACNM could reached the equilibrium within 30 min. The adsorption process was better kinetically fitted with the pseudo-second-order kinetic model and Langmuir isothermal model, suggesting that monolayer chemical adsorption was the dominant adsorption process. The removal efficiency of SMX reached 99.18%, and the adsorption capacity was 13.59 mg g−1. The adsorption mechanism was also studied. ACNM retained 96.8% of the initial adsorption capacity after 3 cycles. Column adsorption experiments were studied to determine the best adsorption conditions.

Polyaniline-coated core-shell silica microspheres-based dispersive-solid phase extraction for detection of benzophenone-type UV filters in environmental water samples

Polyaniline-modified core-shell mesoporous silica (CSMS@PANI) nanocomposite microspheres are synthesized as adsorbent in dispersion-solid phase extraction (d-SPE) for enrichment and purification of benzophenone-type UV filters. The synthesized CSMS@PANI nanocomposite microspheres exhibit large specific surface area (33.45 m2/g) and uniform fibrous shell (microsphere diameter of 1.3 μm, outer silica shell thickness of 120 nm, pore diameter of 12.04 nm), which can greatly improve the extraction efficiency of the samples. Combining CSMS@PANI based d-SPE with sheathless capillary electrophoresis-tandem mass spectrometry for detection, we can achieve sensitive determination of six benzophenone-type UV filters with the detection limit of 0.6 pg/mL-0.2 ng/mL and the enrichment factors of 470-660. The method is successfully applied for ultrasensitive detection of trace amount benzophenone-type UV filters in environment water samples. It is indicated that the method has the advantages of rapid and efficient enrichment, high sensitivity, and excellent repeatability. Our study extends the application of core-shell mesoporous silica materials and would be of value for pretreatment of trace-amount and complex real samples.

Plasmolysis-inspired yolk–shell hydrogel-core@void@MXene-shell microspheres with strong electromagnetic interference shielding performance

A high-performance electromagnetic interference shielding film contains PNIPAM@void@PS@Ti3C2Tx nanocomposite microspheres, whose maximum EMI SE value of the film reaches 72 dB at 9.5 GHz with a thickness of 25 μm.

Aminosilicate modified mesoporous anatase TiO2@graphene oxide nanocomposite for dye-sensitized solar cells

Highly ordered aminosilicate modified mesoporous anatase TiO2 graphene oxide (mTiO2@GO/NH2) nanocomposite microspheres are prepared by hydrothermal method and are investigated using various spectral and microscopic techniques. X-ray photoelectron spectroscopy and Fourier-transform infrared spectral analyses confirmed the presence of NH2 groups in the mTiO2@GO/NH2 nanocomposites. The mTiO2@GO/NH2 exhibits lower photoluminescence intensity than bare mesoporous TiO2 microspheres, disclosing an efficient photoelectron transfer from the mesoporous TiO2 to GO through aminosilicate chain. Atomic force microscopic analysis reveals that mTiO2@GO/NH2 thin film has highly ordered porous structure. The highly porous mTiO2@GO/NH2 exhibits good dye loading for light harvesting and allow good electrolyte contact, which minimizes the back-electron transfer between photoanode and oxidized dye molecules. The dye-sensitized solar cell (DSSC) based on mTiO2@GO/NH2 nanocomposite photoanode, with optimum amount of (3-aminopropyl)triethoxysilane (APTES), delivers an overall photo-conversion efficiency of 5.11%, which is 2.5-fold higher than that of the DSSC based on pure mesoporous TiO2 microspheres (mTiO2 MS) photoanode. The significant photovoltaic performance of the present DSSC based on mTiO2@GO/NH2 photoanode is due to synergistic effects between the TiO2 and GO heterojunction.

In situ fabrication of graphene-scaffold poly(acrylamide-acrylic acid-4-acryloylmorpholine) microspheres as a novel plugging agent for profile control

There has been growing interest in using nanomaterials to improve the comprehensive properties of polymer microspheres as plugging agents in the oil industry. Chemically functionalized graphene was prepared via water-phase direct exfoliation by cell fragmentation. The resultant graphene nanosheets were used to fabricate poly(acrylamide-acrylic acid-4-acryloylmorpholine)-based nanocomposite microspheres via in situ emulsion polymerization. Microspheres containing 0.3 wt% graphene (Graphene 0.3/terpolymer) showed high water retention and heat and shear resistance. Moreover, these microspheres exhibited improved nanomechanical properties, implying high dispersity and flowability in aqueous media. A rheology test demonstrated that the suspension of Graphene 0.3/terpolymer behaved as a Newtonian fluid under high shear conditions, which indicated an improvement in the migration ability in the plugging process. The substantially improved comprehensive properties ensured a deep profile control and enhanced oil recovery of Graphene 0.3/terpolymer microspheres. This research revealed that graphene can serve as a promising filler for fabricating high-performance microspheres in industry.

Polymer Nanocomposite Microactuators for On-Demand Chemical Release via High-Frequency Magnetic Field Excitation.

On-demand delivery of substances has been demonstrated for various applications in the fields of chemistry and biomedical engineering. Single-pulse release profile has been shown previously for micro/nanoparticles in different form factors. However, to obtain a sustained release, a pulsatile release profile is needed. Here, we demonstrate such a release profile from polymer magnetic nanocomposite microspheres loaded with chemicals. By exciting the microactuators with AC magnetic fields, we could achieve up to 61% cumulative release over a five-day period. One of the main advantages of using a magnetic stimulus is that the properties of the environment (e.g., transparency, density, and depth) in which the particles are located do not affect the performance. The operating magnitude of the magnetic field used in this work is safe and does not interact with any nonmetallic materials. The proposed approach can potentially be used in microchemistry, drug delivery, lab-on-chip, and microrobots for drug delivery.

ZnO/C nanocomposite microspheres with capsule structure for anode materials of lithium ion batteries

Well-designed nanostructures are very critical to the lithium-storage performance of electrode materials. To enhance the electrochemical performance of zinc oxide anode materials, a capsule structure, composed of carbon shell and its encapsulating ZnO microsphere, is designed. This capsule structured ZnO/C nanocomposite microspheres are prepared by a sol-gel method combined with two calcination processes. The carbon capsule shows great advantages of enhancing the structural stability of active material, reducing the formation of solid electrolyte interface (SEI) layer, and improving the conductivity of electrode. These factors are quite beneficial to the improvement of cycling stability, initial coulombic efficiency and rate capability. Consequently, capsule structured ZnO/C nanocomposite microspheres deliver an initial charge capacity of 790 mA h g−1, an initial coulombic efficiency of 71%, and a reversible capacity retention of 63% after 100 cycles, all of which are higher than those of pure ZnO microspheres. These results suggest that the design of carbon encapsulated ZnO microsphere is quite effective for enhancing the lithium-storage properties and can also show general significance for developing high-performance electrode materials.

A Nanocomposite Vehicle Based on Metal-Organic Framework Nanoparticle Incorporated Biodegradable Microspheres for Enhanced Oral Insulin Delivery.

Oral insulin delivery has revolutionized diabetes treatment, but challenges including degradation in the gastrointestinal environment and low permeation across the intestinal epithelium remain. Herein, to overcome these barriers, we developed a novel biodegradable nanocomposite microsphere embedded with metal-organic framework (MOF) nanoparticles. An iron-based MOF nanoparticle (NP) (MIL-100) was first synthesized as a carrier with an insulin loading capacity of 35%. The insulin-loaded MIL-100 nanoparticles modified with sodium dodecyl sulfate (Ins@MIL100/SDS) promoted insulin permeation across Caco-2 monolayer models in vitro. To improve resistance to the gastric acid environment, Ins@MIL100/SDS nanoparticles were embedded into a biodegradable microsphere to construct the nanocomposite delivery system (Ins@MIL100/SDS@MS). The microspheres effectively protected the MOF NPs from rapid degradation under acidic conditions and could release insulin-loaded MOF NPs in the simulated intestinal fluid. After the oral administration of Ins@MIL100/SDS@MS into BALB/c nude mice, increased intestinal absorption of the insulin was detected compared to the oral administration of free insulin or Ins@MIL100/SDS. Furthermore, significantly enhanced plasma insulin levels were obtained for over 6 h after oral administration of Ins@MIL100/SDS@MS into diabetic rats, leading to a remarkably enhanced effect in lowering blood glucose level with a relative pharmacological availability of 7.8%. Thus, the MOF-nanoparticle-incorporated microsphere may provide a new strategy for effective oral protein delivery.

Edible alginate/chitosan-based nanocomposite microspheres as delivery vehicles of omega-3 rich oils

A new series of alginate/chitosan-based nanocomposite microspheres was developed to achieve the maximum health benefit and to minimize the oxidation of omega-3 rich oils (flaxseed or fish oils). The nanocomposite microspheres incorporate curcumin (Cur) as natural antioxidant, and have been prepared using a three-step procedure (oil-in-water (o/w) emulsification, gelation and microencapsulation). The average particle size of Cur-free and Cur-loaded nanocomposites ranged between 139 and 153 nm. The presence of omega-3 rich oils in core of the formulated microspheres was confirmed by XRD and FTIR. Optical microscopy, stereo microscopy, SEM and AFM showed a spherical shape of the microspheres. Microencapsulation efficiency, oxidative stability, release profile of oils as well as the antioxidant and antibacterial activities were investigated. The results suggested that the microspheres could be applied as effective and safe edible vehicles for hydrophobic nutraceuticals like omega-3 rich oils with broad spectrum antibacterial activity.

Encapsulation of anion-cation organo-montmorillonite in terpolymer microsphere: structure, morphology, and properties

Abstract Exfoliated organo-montmorillonite (O-Mt) layers were successfully encapsulated in a terpolymer microsphere (PAAA) of acrylamide (AM)/acrylic acid (AA)/2-acrylamido-2-methylpropanesulfonic acid (AMPS) via in situ inverse suspension polymerization, with the aid of the organic modification by cetyltrimethylammonium bromide (CTAB) and sodium lauryl sulfonate (SLS). The chemical structure and properties of the Mt were characterized by Fourier transform infrared (FTIR), X-ray diffraction (XRD) and thermogravimetric analysis (TGA), which showed that SLS molecules successfully intercalated Mt interlayers and enhanced the thermostability of Mt. The microsphere morphologies of the polymer and its nanocomposites were detected by scanning electron microscopy (SEM). The results of X-ray diffraction (XRD) and transmission electron microscopy (TEM) confirmed that the exfoliated O-Mt dispersed in the polymer matrix. The introduction of well-dispersed O-Mt layers significantly enhanced the comprehensive performance of these microspheres, including thermostability and plugging properties. The T max of PAAA/1.5 wt.% O-Mt nanocomposite is increased by 46°C compared to the pure terpolymer. The plugging rate of PAAA/2.0 wt.% O-Mt reached up to 85.8%. Therefore, these selected nanocomposite microspheres can provide an effective plugging in the high-permeability layers.

Abstract No. 690 Magnetic resonance imaging–visible and triggered-degradable nanocomposite microsphere for on-demand temporary embolic agents

Temporary embolization of vessels plays a critical role in many angiographic procedures. However, predictability and reproducibility of vessel recanalization is limited, and in these situations permanent occlusion may be undesirable. The purpose of this study is to evaluate the feasibility of MRI visible and triggered degradable nanocomposite microspheres for a temporary embolic agent. Microspheres composed by superparamagnetic iron oxide nanocluster and alginate were fabricated with spray atomization and coagulation with CaCl2 solution. Size and morphology of the fabricated microspheres with different precursor concentrations and various distance between nozzle and spray were characterized by optical microscope and scanning electron microscope. MR T2 contrast effect of microspheres was measured with 7 T MRI. Triggered degradation of microspheres using various concentration of chelating agents (EDTA) was investigated. In vivo, hepatic arteries of New Zealand white rabbits (n = 3) were occluded by the intra-artery (IA) infused microspheres. Recanalization with a chelating agent were subsequently examined by angiography. The occlusion and recanalization of hepatic arteries were re-confirmed with a perfusion MR in Magnevist contrast-enhanced 3 T MR scans. Uniform-sized microspheres composed by 2%w/v sodium alginate and 5%w/w iron oxide were fabricated with 20 psi spray pressure. Iron oxide contributed to significant MR T2 contrast effect of the microspheres. Chelating agents (∼30 mM) rapidly dissolved the calcium crosslinked microspheres in both water and serum. In vivo angiography demonstrated fast recanalization of embolized right hepatic artery with the chelating agent. Finally, contrast-enhanced MRI showed the occlusion by microspheres and recanalization upon IA infusion of chelating agents. H&E and Prussian blue staining displayed dissolved microspheres in the tumor regions. Nanocomposite microspheres by a simple spray method demonstrated MRI visibility and fast triggered degradation in vitro and in vivo. Further studies will characterize this new on-demand temporary embolic agent.

IN VITRO EVALUATION OF 5-FLUOROURACIL RELEASE BY MICROSPHERES BASED ON CHITOSAN / MONTMORILLONITE/ AVALIAÇÃO IN VITRO DA LIBERTAÇÃO DE 5-FLUOROURACIL POR MICROESFERAS À BASE DE QUITOSANO / MONTMORILONITE

5-fluorouracil (5-FU) is one of the most widely used chemotherapeutic compounds for cancer treatment and its rapid metabolization and non-uniform oral absorption are the limitations for its use as an oral chemotherapy. Therefore, this study was performed to evaluate the influence of a 5-fluorouracil (5-FU) nanocomposite microspheres with different diameters to test on a controlled release system in the gastrointestinal environment. 5-FU was incorporated into the chitosan/montmorillonite nanocomposite microspheres through the intercalation method. The microspheres containing the 5-FU were characterized by X-ray diffraction (XRD), scanning electron microscopy (SEM) and optical microscopy (OM). In vitro release fractions at different pHs (1.2, 7.4 and 10.0) were investigated by UV-vis spectroscopy. The release profile of 5-FU for the systems studied was adjusted through the Korsmeyer-Peppas kinetic model, and the results suggested that the mechanism of controlled release at pH 7.4 and 10 occurs by diffusion. In addition, the 5-FU microspheres diameter and roughness directly interfere with the release rate and the released fraction, since the F1 / F2 systems showed a difference in the released fraction of 5-FU of 7.97% and for the systems F3 / F4 the difference was 2.86%. The prepared F1, F2, F3 and F4 systems are suitable for delivery of 5-FU to the gastrointestinal environment in a controlled manner.

Complementary multiple hydrogen-bond-based magnetic composite microspheres for high coverage and efficient phosphopeptide enrichment in bio-samples.

Due to the number of phosphorylation sites, mono- and multiple-phosphopeptides exhibit significantly different biological effects. Therefore, comprehensive profiles of mono- and multiple-phosphopeptides are vital for the analysis of these biological and pathological processes. However, the most commonly used affinity materials based on metal oxide affinity chromatography (MOAC) show stronger selectivity toward mono-phosphopeptides, thus losing most information on multiple-phosphopeptides. Herein, we report polymer functionalized magnetic nanocomposite microspheres as an ideal platform to efficiently enrich both mono- and multiple-phosphopeptides from complex biological samples. Driven by complementary multiple hydrogen bonding interactions, the composite microspheres exhibited remarkable performance for phosphopeptide enrichment from model proteins and real bio-samples. Excellent selectivity (the molar ratio of nonphosphopeptides/phosphopeptides was 5000 : 1), high enrichment sensitivity (2 fmol) and coverage, as well as high capture rates of multiple-phosphopeptides revealed their great potential in comprehensive phosphoproteomics studies. More importantly, we successfully captured the cancer related phosphopeptides (from the phosphoprotein Stathmin-1) and identified their relevant phosphorylation sites from oral carcinoma patients' saliva and tissue lysate, demonstrating the potential of this material for phosphorylated disease marker detection and discovery.

Synthesis and characterization of poly(AM-SSS-AMPS)/ O-MMT nanocomposite microspheres with tailored nanomechanical properties

In order to overcome the inherent defects of traditional polymer microspheres as plugging agent used in oilfields, including weak mechanical properties, low dispersity in water and poor adaptability to harsh conditions, an organo-modified montmorillonite (O-MMT) was incorporated to form an exfoliated structure in acrylamide/sodium 4-styrenesulfonate/2-acrylamido-2-methyl propane sulfonic acid (AM-SSS-AMPS) terpolymer matrix via in-situ polymerization. Such exfoliated structure not only exhibited a considerable enhancement in the comprehensive properties of nanocomposites, such as viscoelasticity, heat and shear-resistance, but also improved nanomechanical properties of microspheres. The results of nanomechanical properties showed that the energy dissipation and adhesion of nanocomposite with 3.0 wt% O-MMT were decreased to only 1.9% and 4.7% of those of the original terpolymer, respectively, implying the reduction in the agglomeration and energy consumption of microspheres in aqueous suspension. Rheology test demonstrated that the suspension (5.0 wt%) of nanocomposite microsphere with 2.0–3.0 wt% O-MMT behaved as pseudoplastic fluid, Newtonian fluid and dilatant fluid in turn at the shear rate from 10 s−1 to 1000 s−1, which indicated a better arrangement of microspheres in suspension under shear stress. G′ and G′′ of the suspension of nanocomposite microspheres with 3.0 wt% O-MMT were 696.6 times and 84.4 times higher than those of the terpolymer suspension, respectively, and the corresponding viscosity was 10.4 times higher at 90 ℃. These superior properties of nanocomposite microspheres will meet the tough requirements of oilfield development.

Unexpected activity of magnetically separable Fenton catalyst in clay slurries

ABSTRACT Maghemite/silica nanocomposite microspheres (γ-Fe2O3/SiO2 MS) have been tested as magnetically separable heterogeneous Fenton catalyst in beidellite clay slurries in the presence of methylorange (MO) as a model pollutant. Due to its strong magnetic susceptibility, the catalyst was easily recovered from the clay slurries by a selective magnetic sorting, even in highly concentrated slurries. The Fenton oxidation of MO was strongly enhanced in the clay slurries in comparison to the reaction in aqueous phase, highlighting a synergistic catalytic effect. The influence of different experimental parameters such as the presence of specific Reactive Oxygen Species (ROS) scavengers, pH, H2O2, catalyst and clay concentrations, on the catalytic activity was also evaluated. Contrary to what was observed in aqueous phase, generation of hydroxyl radicals via the Haber–Weiss mechanism was not the unique pathway that caused MO degradation in the beidellite slurries. We also observed that the synergistic effect is more marked at pH near neutrality and low amounts of H2O2 and clay. Furthermore, the unchanged activity of the catalyst during five successive cycles together with the low level of iron leaching, makes it suitable candidate for an application as a magnetic heterogeneous Fenton catalyst in wastewater treatment, especially for surface waters or sludges naturally containing fine clay particles.

Recyclable Au/SiO2-Shell/Fe3O4-Core Catalyst for the Reduction of Nitro Aromatic Compounds in Aqueous Solution.

Highly stable gold nanoparticles immobilized on the surface of amine-functionalized nanocomposite microspheres possessing a magnetite (Fe3O4) nanoparticle core and a silica (SiO2) shell (Au/SiO2-shell/Fe3O4-core) were prepared. These gold nanocomposite catalysts were tested for 4-nitrophenol (4-NP) and 2-nitroaniline (2-NA) reduction in aqueous solution in the temperature range 293–323 K and in the presence of aqueous NaBH4 reducing agent. The magnetically recyclable gold catalyst showed high stability (∼3 months), efficient recyclability (up to 10 cycles), and high activity (∼100% conversion within 225 s, ∼700 ppm 4-NP or 2-NA). The pseudo-first-order apparent reaction rate constants (k) of 4-NP and 2-NA reduction were 7.5 × 10–3 and 4.1 × 10–3 s–1, respectively, and with an apparent catalytic activity of 4.48 × 10–8 kmol/(m3 s).

A superparamagnetic ZnFe2O4@NH2-SiO2@PMDI@ dithizone microspheres as an effective selective adsorbent for Pb2+ from wastewater

Herein, a paramagnetic multilayer ZnFe2O4@NH2-SiO2@PMDI@dithizone (ZNPD) nanocomposite microspheres were first devised and constructed via a series of solution processes, and polydiphenylmethane diisocyanate (PMDI) is in situ synthesized and coated on the surface of ZnFe2O4@NH2-SiO2. The nanocomposites were used to absorb Pb2+ ions from dilute solutions prior to a determination by FAAS. Some critical parameters about adsorption properties of the as-prepared ZNPD nanocomposite microspheres were investigated, including influence the initial concentration of Pb2+, solution pH, the dose of absorbents, the reusability. The results show that the synthesized nano-adsorbent present wide acidic resistance, excellent adsorption capacity and sorption/desorption speed, facile separability, and admirable reusability. The adsorption capacity of the absorbents was 267.2 mg/g, and the adsorption equilibrium finishes in 10 min. Pb2+ ions are almost desorbed from the extractant by a given EDTA solution in 20 min. Its adsorption capacity is hardly loss after six times of adsorption-regeneration cycles.

Synthesis and Preparation of Chitosan/Clay Microspheres: Effect of Process Parameters and Clay Type.

This work aimed to prepare chitosan/clay microspheres, by the precipitation method, for use in drug carrier systems. The influence of the process parameters, particularly two airflows of the drag system (2.5 and 10 L·min−1) on the microspheres physical dimensions and properties, such as microstructure, degree of swelling and porosity were evaluated. The samples were characterized by optical microscopy (OM), scanning electron microscopy (SEM) and X-ray diffraction (XRD). Water absorption and porosity tests were also performed. The results showed that the process parameters affected the size of the microspheres. The diameter, volume and surface area of the chitosan/clay microspheres decreased when they were prepared with the higher airflow of the drag system. The microspheres presented a porous microstructure, being the pore size, percentage of porosity and degree of swelling affected not only by the process parameters but also by the type of clay. Hybrids (chitosan/clay) with intercalated morphology were obtained and the hybrid prepared with montmorillonite clay at higher airflows of the drag system presented the greatest interlayer spacing and a more disordered morphology. Thus, it is certain that the chitosan/clay nanocomposite microspheres prepared with montmorillonite (CL clay) at higher airflows of the drag system can have good drug-controlled release properties.

Facile synthesis and low concentration tylosin adsorption performance of chitosan/cellulose nanocomposite microspheres

Antibiotic pollution in tap water, surface water, and effluent needs to be controlled in China. Adsorption is an economical and eco-friendly way to solve the antibiotic contamination problem, such as tylosin. In this study, the chitosan/cellulose nanocomposite adsorbents entrapped with activated carbon are prepared by a sol-gel phase inversion method. Structures and properties of the adsorbents are characterized by SEM, EDXS, BET, XRD, FTIR XPS and Zeta potentials. The adsorption behavior of CCM-AC on tylosin is determined by batch and fixed-bed adsorption experiments, while their adsorption mechanism is also studied. The maximum adsorption capacity is 59.26 mg g−1, while the adsorption behavior is in accordance with the Langmuir equation and pseudo-second-order kinetics. These results confirm that the tylosin adsorption process is affected by chemical and physical interactions, and the adsorbent can be captured by tylosin with H-bond, electrostatic and π-π electron-donor-acceptor interaction. Adsorption experiments are significantly affected by pH.