Nail Care Products Research Articles

Over-the-counter cosmeceuticals: Exploring usage patterns and attitudes among Indians

Objectives: The study’s objectives were to find the prevalence of over-the-counter (OTC) usage of skin, nail, and hair care products and to understand the knowledge, attitudes, and practices (KAPs) of the Indian population presenting to a non-dermatology outpatient department (OPD) for various indications concerning this usage. Materials and Methods: This was a cross-sectional questionnaire-based study, conducted over a year, in which 668 consenting Indians aged 18–60 years, representing various socioeconomic backgrounds were surveyed through Google Forms regarding the OTC cosmeceutical usage in a non-dermatology OPD. Results: This KAP study was conducted on 668 participants, of whom the majority were middle-aged males (481 [72.01%]), with a diverse socioeconomic range, with the upper-middle class making up the largest segment (264 [39.52%]). Allopathy was the primary treatment choice for 347 (51.95%) of participants, with 566 (84.73%) preferring professional healthcare over self-medication. Social media was a significant source of skincare information, with Google Ads (279 [41.8%]) and Instagram (84 [12.6%]) being popular platforms. While doctors’ advice influenced 270 (40.4%) of participants in their skincare choices, word-of-mouth played a role, with 251 (37.57%) agreeing it was helpful. OTC usage was found to vary by socioeconomic class and treatment type. Oral OTC products were preferred for skin health, especially in the upper class, while fairness creams were more common among the lower class. Conclusion: Despite the growing reliance on social media for skincare information, traditional sources such as word-of-mouth and TV still hold sway, indicating a mix of modern and conventional influences. The frequency and type of OTC product usage varied across socioeconomic classes, with oral products like vitamin supplements leading in the upper class and fairness creams leading in the lower class, reflecting the societal pressure for a fair complexion in this subset.

Safety assessment for nail cosmetics: Framework for the estimation of systemic exposure through the nail plate

All cosmetics products, including nail care products, must be evaluated for their safety. The assessment of systemic exposure is a key component of the safety assessment. However, data on the exposure, especially via ungual route (nail plate) are limited. Based on the physicochemical properties of human nails and permeability data of topical onychomycosis drugs, the nail plate is considered a good barrier to chemicals. We examine factors impacting penetration of nail care ingredients through the nail plate, including properties of the nails of the ingredients and formulations. The molecular weight, vapor pressure, logP, water solubility, and keratin binding, as well as formulations properties e.g., polymerization of acrylate monomers are considered important factors affecting penetration. To estimate systemic exposure of nail care ingredients through the nail plate, a standardized framework is applied that quantifies the impacts of these properties on penetration with an adjustment factor for each of these influencing properties. All the adjustment factors are then consolidated to derive an integrated adjustment factor which can be used for calculation of the systemic exposure dose for the ingredient. Several case studies are presented to reflect how this framework can be used in the exposure assessment for nail cosmetic products.

Emission characteristics, environmental impact, and health risk assessment of volatile organic compounds (VOCs) during manicure processes

In recent years, the nail industry has been widely popular in China, and the use of nail care products has also significantly increased. Due to its high content of volatile solvents, the released VOCs not only have a negative impact on indoor air quality but also pose a health threat to nail salon workers who are highly exposed to such environments. The objectives of this research were to characterize VOCs emissions from detailed manicure processes and to evaluate the impact on the environment and health risks. Results showed that the VOCs concentration in the anti-warping treatment process was much higher than that in other manicure steps, at 360.69 mg/m3, making its contributions of OFP and SOA equally prominent. The trend of concentration contribution was similar to that of OFP, and OVOCs were the most significant contributor to the VOCs components in the whole manicure process. Since organic solvent nail gels were also frequently used in most steps, the main VOCs were methanol, ethanol and ethyl acetate. Aromatics were the component that contributed the most to SOA, and its contributions in all processes were >85 %. Health risk assessments performed in our study indicated that acrolein was the main non-carcinogen, and the carcinogenic risk of this study could be ignored. The results of this study can be used as a basis for controlling VOCs emission and reducing exposure to VOCs in nail salons.

Nail cosmetics: What a dermatologist should know!

Nail cosmetics industry is growing at an enormous rate globally due to a surge in nail care all around the world. Various nail cosmetics are available, such as nail polish along with its variants like shellacs, finishes, artificial nails, adornments, and nail polish removers. Nail cosmetics serve aesthetic as well as therapeutic purposes, with the end result being smooth, attractive nails. Nail grooming procedures have evolved from a basic manicure to many other advanced procedures like gel nails, nail tattooing, etc. Although a majority of nail cosmetics are considered safe, they may have potential complications, including allergic and irritant reactions, infections, and mechanical effects. The majority of the procedures related to nail enhancement are not performed by dermatologists but by beauticians with inadequate or no knowledge of the nail's anatomy and functions. The hygiene at the so-called nail-salons/beauty parlours is not standardized, leading to acute complications like paronychia and nail dystrophy following matrix injury. The use of nail cosmetics has become widespread, making it essential for dermatologists to be aware of the nail care products, aesthetic procedures pertaining to nails, and related adverse effects.

Chemicals of concern in personal care products used by women of color in three communities of California.

Personal care products (PCPs) may contain chemicals associated with adverse health effects. Prior studies found differences in product use by race/ethnicity and suggest some women are disproportionately exposed to chemicals of concern (CoCs). We quantified chemicals linked to cancer, reproductive or developmental harm, or endocrine disruption in PCPs used by women of color. We documented PCPs in stores frequented by Black, Latina, and Vietnamese women in their communities in California and CoCs on ingredient labels of 546 unique hair, skin, makeup, nail, deodorant/perfume, and intimate care products. Community partners chose 31 products for a combined targeted and suspect screen (National Institute of Standards and Technology mass spectral library search) two-dimensional gas chromatography time-of-flight mass spectrometry (GCxGC-TOFMS) analysis to detect chemicals not on ingredient labels. We found that 65% of labels included CoCs, and 74% of labels had undisclosed ingredients listed as "fragrance." The most prevalent chemicals were parabens, cyclosiloxanes, and formaldehyde releasers. GCxGC-TOFMS found additional CoCs, including fragrances, solvents, preservatives, ultraviolet filters, and contaminants. These findings contribute to awareness of potentially hazardous chemicals in PCPs, can help estimate disparities in chemical exposure, and complement research on health inequities due to chemical exposures from various contributors. This study is one of the first detailed assessments of chemicals of concern found in various types of PCPs used by several racial/ethnic groups. We found that over half of the 546 products selected by community partners as marketed to and/or used by them contained ingredients linked to cancer, reproductive or developmental harm, or endocrine disruption. Laboratory analysis identified additional chemicals in a subset of products, including unlabeled fragrance chemicals and contaminants. Elucidating exposures to chemicals in PCPs is important for risk assessment and health inequity research.

Patterns of personal care product use and their association with sociodemographic characteristics along with endocrine disrupting chemicals among reproductive-aged Black women

BACKGROUND: Compared to White women, Black women in the United States are exposed to higher, more hazardous concentrations of endocrine disrupting chemicals (EDCs), which are found in personal care products. Personal care product use differs by race/ethnicity across multiple product categories such as hair care, skin care, and feminine hygiene products. These differential patterns of exposure are important as they may contribute to environmental health disparities including increased risk of breast cancer, cardiometabolic outcomes, adverse birth outcomes, and uterine fibroids. We previously examined hair product use patterns among reproductive-aged Black women and found that women with higher socio-economic status were more likely to use more products. Our objective was to expand that work to include a wider range of product types including cosmetics, skin care products, nail care products, and feminine hygiene products. AIM: Identify and describe distinct personal care product use patterns and their correlates among a cohort of reproductive-aged Black women living in Detroit, Michigan. METHODS: Using self-reported data, we employed latent class analysis to determine distinct personal care product use patterns among women enrolled in the Study of Environment, Lifestyle and Fibroids. We compared self-reported sociodemographic characteristics across latent classes and examined whether classes were associated with urinary concentrations of EDCs. RESULTS: We will describe the latent classes and report their association with (1) sociodemographic characteristics, and (2) urinary concentrations of EDCs. CONCLUSIONS: The results of this work may be used to address whether product use patterns and related chemical exposures are associated with health outcomes that disproportionately impact Black women. Such information would help identify subgroups of women who may particularly benefit from intervention and potentially modifiable exposures that may be amenable to targeted public health interventions. KEYWORDS: personal care products; Black women; exposure; endocrine disrupting chemicals; latent class analysis

Application of a three-dimensional scanner to the quantitative assessment of the nail plate condition after a hybrid manicure procedure-Preliminary study.

About 90% of women worldwide use nail care products, including manicure ones. A manicure procedure results in nail damage, therefore it is necessary to search for new, objective methods of assessing the impact of the procedures and products applied within the nail plate. In this study, an attempt was made to quantify the impact of manicure procedures on the nail plate condition. Twenty thumb nail plates were examined. Before the manicure procedures, alginate casts were prepared for each of the subjects. The analysis of the three-dimensional (3D) nail surface structure included the assessment of the nail sections and the assessment of differences in the nail structure after superposition of 3D images of the nail plates before and after the manicure procedures. The obtained results show that the nail plate structure changed to a similar extent in each measured section after the manicure procedure. A change in the height of the nails is not a desirable phenomenon as it suggests damage to the nail caused by the substances included in the preparations applied to the nails, acetone, or filing the nail plate. This proves the great influence of the technique of removing artificial nails on the structure of the natural plate. The use of a 3D scanner allows for precise, biometric, quantitative, and repeatable measurements of changes in the nail structure after a manicure procedure. The use of the hybrid and gel manicure procedure causes significant damage to the nail plate, especially in its distal portion.

Safety Assessment of Cuticle Remover Cosmetics In Vivo and In Vitro

Recently, the issue of the harmful effects of nail care products has been posed. In case of cuticle remover, information on hazards of chemical substances is limited and product safety reports are also insufficient. This study evaluated the safety of the top three commercially selling cuticle removers that are widely used in nail care: Blue cross, Zero cleanser and Flower vita cuticle cares. To measure the pH level of cuticle remover cosmetics, distilled water and DMEM. The toxic effect of cuticle removers on cultured HaCaT was identified by MTT-assay. The patch test was performed to evaluate the occurrence of erythema on the patch area according to the criteria of ICDRG after applying the cuticle remover cosmetics (as is). Adherence to the cosmetic pH measurement guidelines, it w as confirmed that the blue cross product did not meet the pH standard of the final product of the domestic cosmetic method. When measuring the pH by diluting DMEM with a solvent, Flower vita product maintained a pH close to Neutral 7.0 overall. All three cuticle removers demonstrated dose-dependent cytotoxic on HaCaT cell. The viability of cells treated with 10 μg/mL Blue cross or 10 μg/mL Zero cleanser was presented below 10%. Otherwise, Flower vita treatment at concentrations of 0.5~20 μg up to 20 μg/mL did not affect the viability (above 70%) in the HaCaT. Of the patch test, there was positive in one case (3.3%) at 2 weeks. It was observed that a doubful reaction (-/+) to Flower vita and weak positive reactions (+) to Blue cross, and zero cleanser. Taken together, it was shown that the Flower vita product have the lowest cytotoxicity in HaCaT cells and slight allergic reaction, proving more safer than other tw o products <i>in vivo</i> and <i>in vitro</i>.

Contact Dermatitis Associated With Nail Care Products: Retrospective Analysis of North American Contact Dermatitis Group Data, 2001-2016.

Ingredients in nail care products may lead to allergic and/or irritant contact dermatitis. The aims of this study were to determine frequency of contact dermatitis associated with nail care products, characterize associated body sites, and describe causative allergens. A retrospective analysis was conducted with the North American Contact Dermatitis Group data between 2001 and 2016. Of the 38,775 patients tested, 769 (2.0%) had: 1) more than 1 allergic patch test reaction associated with a nail care product (n = 746), 2) irritant contact dermatitis associated with a nail care product (n = 14), or 3) both (n = 9). Primary body sites included the face (43.0%) and hands (27.6%). The top 5 allergens were (2-hydroxyethyl methacrylate (273/482, 56.6%), methyl methacrylate (210/755, 27.8%), ethyl acrylate (190/755, 25.2%), ethyl-2-cyanoacrylate (12/175, 6.9%) and tosylamide (273/755, 36.2%). Frequency of allergy to 2-hydroxyethyl methacrylate (P = 0.0069) and ethyl acrylate (P = 0.0024) significantly increased over the study period, whereas allergy secondary to tosylamide significantly decreased (P < 0.0001). As long-lasting nail techniques become widespread, the prevalence of contact dermatitis to nail care products is expected to increase. Almost one-fifth of nail care product-associated allergens would have been missed without additional screening allergens beyond the North American Contact Dermatitis Group series, underscoring the need for testing to a broad array of allergens.

Nail StrainStress Meter NM 100: A novel in vivo method to characterize biomechanical properties of nails.

Nowadays, nail care products are extremely important both in medical and cosmetic fields. Actually, there are only a very few "in vivo" methods to evaluate the safety and the efficacy of nail products. The new apparatus, based on a recently patented technology, is developed for the "in vivo" evaluation of nails in terms of thickness, structural firmness, flattening, and bending properties. The device analyzes nails by an "in vivo" non-invasive methodology in a timely way and with high accuracy. The assessment of the resistance to compression measures the cohesion of the nail matrix (nail firmness), while the evaluation of the resistance to transversal deformation detects the elasticity of the nail plate. Furthermore, the apparatus is able to assess the nail thickness and the flexibility of their distal edge. The instrument provides nail thickness and several parameters reflecting mechanical properties of nail plate: Viscoelasticity expressed as viscoelasticity index (VI), structural strength/ firmness expressed as Firmness Index (FI), and viscoelasticity of the distal edge expressed as Bending Index (BI). The instruments described in this work represent an innovative apparatus for the safety and efficacy evaluation of nail products in several fields: cosmetics, pharmaceuticals, and medical devices.

Renewable sources: applications in personal care formulations.

A global tendency for products considered environmentally sustainable, and ecologically obtained led the industry related to personal care formulations to fund the research and the development of personal care/cosmetics containing ingredients from natural resources. Furthermore, consumers are aware of environmental and sustainability issueans, thus not harming the environment represents a key consideration when developing a new cosmetic ingredient. In this study we review some examples of active ingredients or raw materials used in cosmetics/personal care/biomedical products that are coming from either through biotechnological systems, or as byproducts of several industries. A skin formulation containing biosynthetic actives, prepared by us and the study regarding its dermocosmetic properties are also described. The need for the standardization processes, the safety assessment tools, the improvement of the exploitation methods of these renewable sources in order the production to be ecologically and economically better are also discussed.

VOC emissions from nail salon products and their effective removal using affordable adsorbents and synthetic jets

Volatile organic compounds (VOCs) like acetone, ethyl and n-butyl acetate, toluene, and formaldehyde have been measured inside nail salons, where they are emitted from nail care products. Exposure to these compounds can have negative health impacts on both workers and costumers, as well as the environment. The objectives of this research were to characterize VOC emissions from typical nail care products and to investigate VOC removal by 3 low-cost adsorbent materials (coco coir, biochar, and activated carbon). The removal studies were performed using acetone as the model VOC in both chamber experiments and mathematical models. The chamber experiments were conducted under both passive and active flow conditions using synthetic jet actuators to determine the effect of local ventilation on the rate of removal. Mass-normalized adsorption rates were determined for acetone using nth-order rate equations. Adsorption rate models were then developed for all adsorbent materials under both flow conditions and used to estimate the effect of low-cost adsorbents in an actual nail salon. Activated carbon provided the best VOC removal compared to the other 2 adsorbent materials tested. The use of active flow with synthetic jets was also shown to enhance adsorption processes for both biochar and activated carbon, but not for coco coir. Model results predicted activated carbon with active flow enhancement could achieve an effective ventilation rate of nearly 300 m3 h−1 if 250 kg were placed in a 1400 m3 salon.

Occupational Exposures Among Hair and Nail Salon Workers: a Scoping Review.

To review the literature published from 2014 to 2019 on hair and nail salon workers concerning exposure assessment, reproductive and respiratory endpoints, and endocrine disruption, in relation to workplace exposures. We identified 29 relevant peer-reviewed publications. Overall, there were insufficient studies to determine whether working in these settings is associated with reproductive health endpoints, although prior studies suggest that reproductive effects are of concern. There is consistent evidence that working in hair and nail salons may increase the risk of respiratory effects. Also, despite the fact that many hair and nail care products contain endocrine disrupting compounds, no recent studies have evaluated endocrine-related endpoints. Moreover, few studies have evaluated chemical exposures in these settings and biomonitoring studies are sparse. Improved exposure assessment of chemical hazards in hair and nail salons is necessary to properly characterize occupational exposures and assess their potential health risks. Further studies on endpoints related to endocrine disruption and reproductive health outcomes among hair and nail salon workers are needed. Improved exposure and epidemiologic studies will help inform chemical exposure mitigation efforts in a vulnerable occupational population, as well as policies related to workplace and consumer product safety.

Cosmetic-Related Injuries Treated in US Emergency Departments: 2002 to 2016.

A retrospective analysis was conducted by using data from the National Electronic Injury Surveillance System for children <5 years who were treated in US emergency departments (EDs) from 2002-2016) for a cosmetic-related injury. An estimated 64 686 (95% confidence interval = 53 037-76 335) children were treated in EDs for cosmetic-related injuries during the 15-year study period. There was no significant change in the rate (slope = 1.1 per 10 000 children per year, P = .95) of injuries over the study period. Injuries were most commonly associated with nail care (28.3%), hair care (27.0%), skin care (25.0%), and fragrance (12.7%) products. Children aged <2 years were most frequently injured (59.3%), and poisoning was the most common diagnosis (86.2%). To our knowledge, this is the first study to use a nationally representative sample to describe the epidemiology of cosmetic-related injuries among children aged <5 years. Unintentional exposure to cosmetics is an important source of injury for young children.

Receptor-based aggregate exposure assessment of phthalates based on individual's simultaneous use of multiple cosmetic products

To estimate realistic exposure to a chemical, the aggregate exposure from multiple consumer products should be considered. A receptor-based aggregate exposure assessment was conducted according to individuals' exposure factors and simultaneous use patterns including co-use and non-use. A product-based aggregate exposure assessment was conducted by product usage rates of population and users’ exposure factors. Two aggregate exposure assessments were compared. Exposure factors for 31 cosmetic products were collected by face-to-face interviews with 1001 members of the Korean population through national representative sampling. The concentrations of phthalates in 214 cosmetic products were analyzed by GC-MS-MS. The average aggregate exposure dose (AED) determined by the receptor-based method for di(2-ethylhexyl)phthalate (DEHP), di-n-butyl phthalate (DnBP), and diethyl phthalate (DEP) were 0.68 ± 0.87, 1.08 ± 5.71, and 2.47 ± 9.05 μg/kg/day, respectively. The cosmetics that contributed most to the receptor-based AED were skin care and body care products for DEHP, nail care products for DnBP, and fragrance and hair care products for DEP. The young female group showed the highest exposure. The product-based aggregate exposure assessment method underestimated high exposure but overestimated average exposure for DnBP and DEP. The receptor-based aggregate exposure assessment method would be used to determine high exposure groups.

A Differences in Consumer Intention on Nail Care Products by Nail Care Shop Type

A Differences in Consumer Intention on Nail Care Products by Nail Care Shop Type

Socioeconomic factors influencing cosmetic usage patterns.

Despite daily exposure to chemicals in cosmetic products, there are few studies on the exposure levels to cosmetics particularly in Asians. We sought to investigate the usage pattern of cosmetics, including eye makeup products, fragrances, color makeups, and hair and nail care products, in Koreans. An online survey of 1,800 participants (908 males and 892 females, aged 15-59 years) from 5 Metropolitan cities (Seoul, Incheon, Daejeon, Daegu, and Busan) in Korea was conducted. For overall types of cosmetics, the proportion of users was 7.1% (range: 0.0-46.3%) in males and 30.7% (range: 1.0-82.8%) in females. The most prevalently used product was perfume (46.3%) in males and lipstick (82.8%) in females. In addition, the mean number of application for overall types of cosmetics was 22.7 (range: 4.6-49.4) times per month in male users and 24.8 (range: 4.2-62.0) in female users. The usage pattern was significantly altered according to demographic and socioeconomic factors, including age group, occupation, and income. This work estimated the prevalences and frequencies of use of a wide collection of cosmetics from a large number of Koreans and found that the usage pattern was significantly associated with demographic and socioeconomic factors.

Screening survey of ocular, nasal, respiratory and skin symptoms in manicurists in Poland.

Manicurists are exposed to various chemicals in nail and skin care products and may develop ocular, nasal, respiratory or skin adverse reactions to them. To investigate the occurrence of ocular, nasal, respiratory and skin problems among manicurists and to identify their causal factors, particularly allergic etiology and occupational origin. Manicurists employed in beauty salons in the central region of Poland were invited to fill in the questionnaire and undergo medical examination, skin prick tests with common aeroallergens, patch tests with European Baseline Series and (Meth)Acrylates Series-Nails and spirometry. In the questionnaire adverse nasal symptoms were reported by 70%, ocular - by 58%, respiratory - by 42%, hand eczema - by 43% of manicurists. In the medical interview, the frequency of those complaints was lower: nasal ones - 41%, ocular - 24%, cough - 18%, hand skin dryness - 20%, hand eczema - 6%. Cough and hand skin dryness occurred significantly more frequently than in the case of controls. Contact allergy was found for 41% of manicurists and 35% of controls. The prevalence of nickel sensitization was high in both groups (38% and 27%, respectively). Only 3 manicurists reacted to (meth)acrylates. The frequency of atopic diseases was similar in compared groups. Irritant nasal and respiratory reactions were significantly more prevalent among manicurists (nasal - 18% vs. 2%, p < 0.01; respiratory - 18% vs. 1%, p < 0.001). Work-related nasal irritant reactions were finally diagnosed for 19%, ocular ones - for 13%, respiratory - for 18% and within hand skin - for 23% of manicurists. The frequency of workattributed irritant mucosal and skin symptoms among manicurists is high. Exposure to acrylates is an important source of mucosal irritant reactions while occlusive gloves cause irritation of hand skin. The prevalence of nickel allergy among Polish females is high. Int J Occup Med Environ Health 2017;30(6):887-896.

Talcum Powder: Problems And Satisfaction Of Consumers

&#x0D; &#x0D; &#x0D; Indian cosmetics and toiletries market is valued at $950 million. The key growth drivers for the cosmetics and toiletries market in India are rapid urbanization, increase in disposable incomes, and changes in people's tastes. The cosmetics market can be segregated into talcum powder, colour cosmetics (lip, eye, face, and nail care products), deodorants, and perfumes. The cosmetics market has been growing at the rate of 15-20% for the last few years. The sector has witnessed growth mainly from medium and low priced category that accounts for 90% of the cosmetic market. Talcum powders are the largest selling single item among cosmetics, since their application either directly to the body or even as a powder base provides a finishing touch to any make-up process. Talcum powders are intended for use on the body. The modern woman and man believe in concealing undue gloss or shine on the face and body. Talcum powder serves precisely this purpose. The success of this product is mainly concerned with the satisfaction of consumers, but, now-a-days they are facing numerous problems while using it.&#x0D; &#x0D; &#x0D;

Renal Function Assessment of Workers Occupationally Exposed to Hair and Nail Care Products in Benin City, Edo State

Renal Function Assessment of Workers Occupationally Exposed to Hair and Nail Care Products in Benin City, Edo State