Ciprofloxacin imprinted polymers have garnered significant attention due to the high demand for application in the monitoring of antibiotics. This study focuses on the synthesis and selective adsorption properties of ciprofloxacin imprinted polymers. The polymers were synthesized via precipitation polymerization technique. Optimal condition was achieved using acetonitrile:water (8:2, v/v) and a molar ratio of ciprofloxacin:acid methacrylic:ethylene glycol dimethacrylate of 1:6:30. Physicochemical characterization utilizing FT-IR, TGA-DSC, SEM, and N2 adsorption isotherm confirmed the desired properties of the polymer. Adsorption properties (kinetic, pH, and isotherm) indicated selective adsorption of ciprofloxacin onto the imprinted polymer with an imprinting factor of 1.34 and adsorption capacity up to 11.6 mg g-1. These findings underscore the potential of the ciprofloxacin imprinted polymer as a stationary phase for solid-phase extraction columns.