Arsenic contamination of water in the Red River and Mekong deltas brings the largest mass poisoning calamity in human history because drinking of arsenic contaminated water can cause cancers of the skin, lungs, bladder and kidney and other harmful diseases. In general, the arsenic exists in difference oxidation states such as –3, 0, +3, and +5, among which As(+3) has been considered as the most dangerous contaminant in the water. Synthesis of nature friendly and low cost, portable, and effective adsorbent for removal of arsenic in contaminated water is very essential for many countries where development of large industrial setup is difficult. In this work, we introduce a facile method for preparation of Iron Oxide (Fe2O3) coated N-doped Titanium Oxide (TiO2) nanoparticles (FNT NPs) towards effective removal of As(III) from drinking water. The FNT NPs were synthesized by a scalable low temperature, solution based hydrothermal method using as Iron(III) chloride (FeCl3), and N‑doped TiO2 NPs as starting materials. The prepared FNT NPs were characterized by Scanning electron microscopy (SEM), Energy-Dispersive X-Ray (EDS), and Transmission electron microscopy (TEM), whereas the As(III) adsorption studied were done using Inductively coupled plasma mass spectrometry (ICP) analysis. Results pointed out that the high quality FNT NPs were successfully synthesized by a low temperature hydrothermal method with uniform size and shape. The adsorption test confirmed that the prepared FNT NPs can effectively remove the As from the water. The results shows 99.34% As(III) form water was adsorbed using the prepared FNT NPs within 60 min. The results shows synthesized FNT NPs, could provide large specific surface area for effective adsorption sites for capturing and removal of As(III) in the water.