To assess the repeatability and agreement between Scheimpflug-based corneal topography, Scansys and Pentacam, in measuring ocular parameters in myopic eyes. A Grade-A tertiary hospital in Beijing, China. Cross-sectional study. The following measurements were performed in 204 patients undergoing pre-operative examinations for refractive surgery from the corneal curvature, astigmatism, corneal thickness, corneal volume, corneal asphericity, anterior chamber depth and volume, and pupil diameters. Repeatability was determined using intraclass correlation coefficient (ICC) with 95% confidence interval (95% CI), Cronbach's Alpha, coefficient of variation (CV), within-subject standard deviation (Sw), test-retest repeatability (TRT), and one-way analysis of variance (one-way ANOVA). The inter-device agreement was determined using paired t-test and Bland-Altman plots. Scansys showed good repeatability in the anterior and posterior corneal flattest meridian (Kf), steepest meridian (Ks), and mean (Km), axis of anterior corneal Ks, anterior corneal astigmatism, pupil central corneal thickness, central corneal thickness, corneal apex thickness, thinnest corneal thickness, corneal volume, photopic pupil diameter, anterior chamber depth and volume. In the agreement study, Bland-Altman plots showed that 95% LoA of corneal curvature, pupil central corneal thickness, corneal apex thickness, thinnest corneal thickness, and corneal volume generated by Scansys and Pentacam were narrow. There were no statistically significant differences in the anterior corneal Kf and Km. Scansys showed good repeatability in measuring corneal curvature of anterior and posterior surfaces, anterior corneal astigmatism, corneal thickness, corneal volume, photopic pupil diameter, anterior chamber volume and depth. Scansys and Pentacam can only be used interchangeably in measuring anterior corneal curvature.