The initiated changes in organic atoms, for example, DNA and proteins, have a serious distinctive nature (ecological elements, infections, ionizing radiation, mutagenic synthetic substances, acquired hereditary modifications, and so forth.). Actuated changes can annihilate the current synthetic (hydrogen) bonds in the local atomic structures or, in actuality, make new substance (hydrogen) bonds that don't ordinarily exist there. In protein structures, the reason for such changes may be the replacement of one or a few explicit amino corrosive deposits (point transformations). At the nuclear level, the substitution of one amino corrosive buildup by another causes basic alterations of the atomic power fields of the earth, which can break significant hydrogen bonds hidden the auxiliary solidness of natural particles. In this work, in view of sub-atomic elements (MD) strategy, we show the impact of mutational structure changes on a few natural protein models.