Mussel-inspired Polydopamine Coatings Research Articles

Bioinspired multifunctional MXene-decorated textile for thermal management, durable self-cleaning, bio-protection and wearable strain sensor

Textile-based wearable electronic devices have gained significant attention due to their promising applications in personal thermal management, human healthcare monitoring, and human motion detection. Herein, a multifunctional MXene-decorated textile has been fabricated as a promising wearable electronic textile for thermal management, durable self-cleaning, bio-protection and wearable strain sensor. In this study, Ti3C2Tx MXene nanosheets, which are followed by surface engineering with mussel-inspired polydopamine coatings and hydrophobic octadecyl trimethoxysilane, are chosen as active materials for constructing multifunctional MXene-decorated textile. Thus, the multifunctional MXene-decorated textile (Cotton@ODMX) is fabricated by spray-coating the hydrophobic MXene-based composites (ODMX) onto the surface of the cotton textile. Such a Cotton@ODMX epitomizes a highly innovative electronic textile that not only retains the flexibility of the original textile, but also possesses remarkable superhydrophobic properties, outstanding photothermal conversion performance, photothermal self-healing capabilities, environmental stability and exceptional photothermal sterilization capabilities. More importantly, Cotton@ODMX is demonstrated to serve as a wearable strain sensor to monitor fundamental human movements, thus highlighting its impressive sensing capabilities. This work offers valuable insights for the development of multifunctional, flexible and wearable electronic devices with promising potential in personal thermal management, human healthcare monitoring, and human motion detection.

In situ green immobilization of palladium nanoparticles onto polydopamine-modified eggshell membrane for catalytic reduction of nitrophenols

4-Nitrophenol (4-NP) poses significant threats to both ecosystems and human health, making it essential and highly beneficial to take effective measures to mitigate its impact. Herein, eggshell membrane (ESM) with mussel-inspired polydopamine coatings (ESM-PDA) was constructed and utilized as a template for the immobilization of Pd NPs, resulting in ESM-PDA-Pd formation. The catalyst ESM-PDA-Pd exhibits exceptional performance in reducing 4-NP, and the TOF (turnover frequency) for ESM-PDA-Pd was determined to be 3.3 × 10−5 mmol·mg−1·min−1. Moreover, ESM-PDA-Pd demonstrates excellent catalytic activity in reducing other nitrophenols, including 2-nitrophenol (0.2196 min−1) and 2,4,6-nitrophenol (0.1177 min−1). Notably, the catalyst demonstrated brilliant recyclability, removing 92.4 % of 4-NP within 20 min after undergoing five consecutive runs. This underscores its potential for sustained and effective use in multiple cycles of nitrophenol reduction reactions. Furthermore, the measured Kapp in various water samples is as follows: ultrapure water (0.135 min−1) > tap water (0.109 min−1) > river water (0.083 min−1), indicating its significant potential for industrial applications.

Mussel-Inspired Polydopamine Coating Enhances the Intracutaneous Drug Delivery from Nanostructured Lipid Carriers Dependently on a Follicular Pathway.

Inspired by the structure and function of the mussel adhesive protein, a facile strategy involving oxidative polymerization of dopamine was proposed for surface modification of nanostructured lipid carriers (NLCs) to promote drug delivery in the skin. The formation of a polydopamine (PDA) layer rounding the surface of NLCs was confirmed by the X-ray photoelectron spectroscopy and the Fourier transform infrared spectroscopy studies. Using terbinafine (TBF) as a model drug, the in vitro permeation study revealed that the PDA coating significantly enhanced the delivery of TBF from NLCs to the deep skin layers, where the follicular pathway played an essential role as suggested by the hair follicle blocking and differential tape stripping experiments, as well as the laser scanning confocal microscopy study by using Nile red as the fluorescent probe. The cellular investigation indicated that the PDA coating led to a higher cellular uptake of nanoparticles in human immortalized keratinocytes (HaCaT) without causing additional cytotoxicity. Using endocytic inhibitors, it was found that the lipid raft/caveolae-mediated endocytosis was strongly involved in the internalization of both the PDA modified and unmodified NLCs. Our results suggested that surface modification of NLCs with PDA coating improved the intracutaneous drug delivery mainly via the follicular pathway, which provided an avenue for the development of potential drug delivery carriers for dermal use.

Antibacterial Properties of Mussel-Inspired Polydopamine Coatings Prepared by a Simple Two-Step Shaking-Assisted Method.

A simple two-step, shaking-assisted polydopamine (PDA) coating technique was used to impart polypropylene (PP) mesh with antimicrobial properties. In this modified method, a relatively large concentration of dopamine (20 mg ml−1) was first used to create a stable PDA primer layer, while the second step utilized a significantly lower concentration of dopamine (2 mg ml−1) to promote the formation and deposition of large aggregates of PDA nanoparticles. Gentle shaking (70 rpm) was employed to increase the deposition of PDA nanoparticle aggregates and the formation of a thicker PDA coating with nano-scaled surface roughness (RMS = 110 nm and Ra = 82 nm). Cyclic voltammetry experiment confirmed that the PDA coating remained redox active, despite extensive oxidative cross-linking. When the PDA-coated mesh was hydrated in phosphate saline buffer (pH 7.4), it was activated to generate 200 μM hydrogen peroxide (H2O2) for over 48 h. The sustained release of low doses of H2O2 was antibacterial against both gram-positive (Staphylococcus epidermidis) and gram-negative (Escherichia coli) bacteria. PDA coating achieved 100% reduction (LRV ~3.15) when incubated against E. coli and 98.9% reduction (LRV ~1.97) against S. epi in 24 h.

Silver-Incorporated Mussel-Inspired Polydopamine Coatings on Mesoporous Silica as an Efficient Nanocatalyst and Antimicrobial Agent.

To tackle severe environmental pollution, a search for materials by economical and eco-friendly preparations is demanding for public health. In this study, a novel in situ method to form silver nanoparticles under mild conditions was developed using biomimetic reducing agents of polydopamine coated on the rodlike mesoporous silica of SBA-15. The synthesized SBA-15/polydopamine (PDA)/Ag nanocomposites were characterized by a combination of physicochemical and electrochemical methods. 4-Nitrophenol (4-NP) and methylene blue (MB) were used as models for the evaluation of the prepared nanocatalysts of SBA-15/PDA/Ag in which the composite exhibited enhanced catalytic performance toward degrading 4-NP in solution and MB on the membrane, respectively. Additionally, compared with that of solid core-shell SiO2/PDA/Ag, tubular SBA-15/PDA/Ag showed the prolonged inhibitory effect on microbial growth as typified by Escherichia coli (60 h), Staphylococcus aureus (36 h), and Aspergillus fumigatus (60 h), which demonstrated efficient control of silver nanoparticles release from the mesopores. The constructed dual-functional SBA-15/PDA/Ag as the long-term antimicrobial agent and the catalyst of industrial products provides an integrated nanoplatform to deal with environmental concerns.

Guided protein/cell patterning on superhydrophilic polymer brushes functionalized with mussel-inspired polydopamine coatings.

A simple approach for preparing bicomponent polymer patterns was developed by coating polydopamine (PDA) on superhydrophilic poly(2-acryl-amido-2-methylpropane sulfonic acid) (PAMPS) brushes. Well-defined and versatile arrays of proteins and cells were achieved without harm to proteins and cells.

Mussel-inspired polydopamine coatings for large-scale and angle-independent structural colors

This is the first time gorgeous structural colors have been presented from polydopamine-based coatingsviaa facile liquid phase deposition.

Mussel-Inspired Polydopamine Coating for Enhanced Thermal Stability and Rate Performance of Graphite Anodes in Li-Ion Batteries.

Despite two decades of commercial history, it remains very difficult to simultaneously achieve both high rate capability and thermal stability in the graphite anodes of Li-ion batteries because the stable solid electrolyte interphase (SEI) layer, which is essential for thermal stability, impedes facile Li(+) ion transport at the interface. Here, we resolve this longstanding challenge using a mussel-inspired polydopamine (PD) coating via a simple immersion process. The nanometer-thick PD coating layer allows the formation of an SEI layer on the coating surface without perturbing the intrinsic properties of the SEI layer of the graphite anodes. PD-coated graphite exhibits far better performances in cycling test at 60 °C and storage test at 90 °C than bare graphite. The PD-coated graphite also displays superior rate capability during both lithiation and delithiation. As evidenced by surface free energy analysis, the enhanced performance of the PD-coated graphite can be ascribed to the Lewis basicity of the PD, which scavenges harmful hydrofluoric acid and forms an intermediate triple-body complex among a Li(+) ion, solvent molecules, and the PD's basic site. The usefulness of the proposed PD coating can be expanded to various electrodes in rechargeable batteries that suffer from poor thermal stability and interfacial kinetics.

Robust Nanoparticle-DNA Conjugates Based on Mussel-Inspired Polydopamine Coating for Cell Imaging and Tailored Self-Assembly.

We have demonstrated that mussel-inspired polydopamine can serve as an intermediate coating layer for covalently attaching oligonucleotides on nanostructures of diverse chemical nature, which are made possible by the universal adhesion and spontaneous reactivity of polydopamine. Our results have shown that polydopamine can strongly bond to representative nanoparticles (i.e., Au nanoparticles and magnetic polymer nanobeads) and form a thin layer of coating that allows for attachment of commercially available DNA with thiol or amine end functionality. The resulting DNA-nanoparticle conjugates not only show excellent chemical and thermal stability and high loading density of DNA, but the linked DNA also maintain their biological functions in directing cancer cell targeting and undergo DNA hybridization to form multifunctional magnetic core-plasmonic satellite assemblies. The generally applicable strategy opens new opportunities for easy adoption of DNA-nanoparticle conjugates for broad applications in biosensors and nanomedicine.