Muskmelon (Cucumis melo L. cvs. Superstar and Mission) transplants were grown in seedling flats with individual cells ranging in volume from 7 to 100 cm3. The smallest cells were in a 338-cell polystyrene flat 33 cm wide × 66 cm long × 4.75 cm deep; the largest cells were in a 32-cell plastic flat 30.5 × 50.8 × 6.5 cm. The study was conducted in Florida and Indiana during the 1993 and 1994 growing seasons. Seedlings of uniform age were transplanted to the field and grown to maturity using standard cultural practices. Early yield of `Superstar' muskmelon, measured as number of fruit per plot or percentage of total yield, increased as transplant cell volume increased. In one trial, plants from 7-cm3 cells produced no early yield, while plants from 100-cm3 cells produced 40% of the total yield in the first three harvests. In three of the four trials, total yield of `Superstar' increased as cell volume increased. Marketable early yield of `Mission' muskmelon, measured as number or weight per plot, increased as cell volume increased in three of four trials. In Florida, total yield of `Mission' also increased as cell volume increased. Size of `Superstar' fruit was not influenced by cell volume. In Florida, size of early `Mission' fruit increased as cell volume increased.