AIM: In our study we assessed the association between hand grip strength and arm circumference, BMI, dominant hand and gender. METHODOLOGY: Our study population includes 146 young adults (Female-84, Male-62) from Guntur medical college, Guntur, Andhra Pradesh. We have calculated each student's BMI (kg/m2). We measured Hand grip strength in (kg) by taking the average of two hand grip attempts using a handspring dynamometer. We measured the Upper arm circumference using a measuring tape in cm around the thickest part of the upper arm. We compared Hand grip strength with arm circumference, BMI, handedness and gender. Results: The mean values for Maximal grip strength in the right hand for severely underweight, underweight, normal, overweight, and obese are 21, 26, 31.1, 31.6 and 32. The mean values for Maximal grip strength in the left hand for severely under-weight, underweight, normal, overweight and obese are 19, 26, 29.4, 29.6 and 30. The mean values for the arm circumference of the muscle in the right limb for severely underweight, underweight, normal, overweight and obese are 20.8, 21.6, 26.2, 28.6, and 30.6. The mean values for the arm circumference of the left-limb muscles in severely underweight, underweight, normal, overweight and obese are 20.3, 21.3, 25.8, 28.4 and 30.4. Pearson coefcient for maximal grip strength and bulk of the right arm is 0.9095, indicating a strong positive correlation. The P-Value is <0.00001, which is signicant at P<0.05. Pearson coefcient for maximal grip strength and the bulk of the left arm is-0.382, indicating a negative correlation. The P value is <0.00001, which is signicant at P<0.05. Conclusion: Maximal Grip Strength is more in males than females. Bulk and Maximal Grip Strength is more in the dominant hand (right hand).Maximal Grip Strength is less in severely underweight and underweight participants. Maximal Grip Strength is more in overweight and obese