To address the attitude coordination and consensus tracking problem in the multi-spacecraft system, a distributed attitude-coordinated strategy based on the Fixed-time theory is proposed. An observer based on second-order integral sliding mode is designed to accurately estimate the compound disturbance, which consists of external disturbance and inertia uncertainties. On the basis of the observed information, a distributed Fixed-time attitude coordination controller is proposed, which can guarantee the attitude tracking errors converge to zero in a fixed time. System stability is analyzed by using the Lyapunov function. Finally, simulations and comparison analysis demonstrate the effectiveness and superiority of the proposed control scheme.