Secondary manifestations of primary disease elsewhere in the body are frequent. One of the less commonly recognized of these is multiple venous thrombosis associated with visceral carcinoma. In an excellent article, Sproul (4) reviews the findings in 4,258 consecutive autopsies with particular reference to venous thrombosis. He found that carcinoma was the most common cause of thrombosis of veins of the neck, abdomen, pelvis, and extremities. Carcinoma of the body and tail of the pancreas was the most common primary lesion, with carcinoma of the stomach and lung next in order but appreciably less in frequency. Of the carcinomas of the body or tail of the pancreas, 31.3 per cent had associated widespread venous thrombosis. Except in one case, .neither inflammation nor invasion of vessels by tumor tissue could be found as a cause of the thrombosis. Haward (2), in a review of 2,903 necropsies, found 70 cases of fatal venous thrombosis. Middle ear disease was first among the primary conditions, with 14 cases,...