Problems In Multiple Systems Research Articles

Ligneous cervico-vaginitis mimicking female genital tract malignancies

Background: Ligneous cervicitis is a rarely reported disease in the literature, and it is commonly misdiagnosed as genital cancer. Patients with ligneous cervicitis can have multiple systemic problems. The lesions resemble malignancies. Multiple biopsies are essential for the diagnosis. Herein, we present 2 cases of ligneous cervicitis, both of which had plasminogen deficiency. Our aim in this report was to discuss these cases with guidance of the literature. Conclusion: Ligneous cervicitis commonly mimics female genital cancers. Hence, it is very important to utilize a multidisciplinary approach in making a differential diagnosis.

A Case Report of Mucormycosis of Faciotemporal Region Mimicking as Bacterial Necrotizing Fasciitis

ABSTRACT Mucormycosis is an invasive and unyielding fungal disease of immunocompromised patients with a reported increase in incidence over last couple of decades. The close resemblance of clinical features of mucormycosis with that of bacterial necrotizing fasciitis can lead to misdiagnosis and thus delay in appropriate management. The case presented here involves a similar scenario when a middle-aged patient with multiple systemic problems reported to the tertiary care hospital 7 days after facial trauma from a road traffic accident. There was a purple black ulcerating lesion over left midface that was misdiagnosed and treated as a case of bacterial necrotizing fasciitis. Despite extensive debridement under general anesthesia and administration of parentral antibiotics, the patient failed to survive. The results of histopathological examination of the debrided tissue, that became available after the death of the patient showed, growth of broad aseptate hyphae characteristic of mucorales. Late presentation, multiple systemic diseases and missed diagnosis of the condition were the main factors that resulted in the death of the patient within 72 hours of presentation. Underlying immunocompromised states and late diagnosis of this condition remain the key issues that need to be addressed in developing countries. A high degree of clinical suspicion and aggressive diagnostic measures combined with prompt medical and surgical treatment are essential to improve the outcome. How to cite this article Jeelani W, Kamal Y. A Case Report of Mucormycosis of Faciotemporal Region Mimicking as Bacterial Necrotizing Fasciitis. World J Dent 2012;3(4):355-358.

Long-Term Ocular Follow-up in a Case With Hereditary Mucoepithelial Dysplasia

Hereditary mucoepithelial dysplasia is a rare desmosomal gap junction abnormality known to produce keratitis and cataracts in addition to multiple systemic problems. It generally carries a poor visual prognosis due to corneal scarring, amblyopia, and side effects of the treatment. The authors present a sporadic case of hereditary mucoepithelial dysplasia with an unusually good visual outcome and suggest that timely and appropriate intervention can improve the visual prognosis of this rare disorder.

Sleepy Heart and Hearty Sleep: Sleep Disorders and Cardiovascular Diseases

Sleep is an active, energizing and blissful activity, which everybody enjoys. Diseases affecting any system of the body can alter sleep and sleep disorders can lead to problems in multiple systems of the body. Much research is going on in the field of sleep medicine and its effects on health. The association between sleep disorders and cardiovascular diseases is well known. Obstructive Sleep Apnea (OSA) is known to cause ischemic heart disease and other related cardiovascular diseases. Severe heart diseases like congestive heart failure also are known to produce sleep disordered breathing. Relationship of cardiovascular diseases to certain phases of the sleep cycles has also been reported. There is a definite need for physicians, cardiologists and sleep specialists to work together in this field of sleep disorders and cardiovascular diseases in order to improve detection and management of these conditions.

The Preferable Use of Port Access Surgical Technique for Right and Left Atrial Procedures

We analyzed the results of mitral valve operations, either alone or in any combination with the tricuspid valve surgeries in the period from January 2001 till June 2004. The period was divided into two parts, classical sternotomy part (C) (110 patients) and minimally invasive port access part (PA) (105 patients), later being used from December 2002 till now. Also, what we were interested in was the total hospital cost of both types of the procedures and if there are any advantages of port access over the classical sternotomy. The mean age was 61.2 +/- 10.2 and 60.3 +/- 12.4 (C versus PA) and mean additive Euroscore was 6.5 versus 4.8 (C versus PA). There were statistically significant differences (P < .0001) in cardiopulmonary bypass time (CPB) and aortic cross-clamp time (AXT) between both groups: CPB C versus PA: 98.3 +/- 33.5 minutes versus 149.2 +/- 44.2 minutes (mean +/- sd), AXT C versus PA: 62.9 +/- 20.6 minutes versus 88.3 +/- 26.8 minutes (mean +/- sd). There were no statistically significant differences in mortality and stroke for both the groups (mortality P = 1, stroke P = .53). There were statistically significant differences in favor of the port access over the classical one for: intensive unit stay (P = .004), postoperative stay in days (P < .0001), blood transfusion (P < .0001), postoperative thoracic bleeding (P < .0001), and extubation time in hours (P < .0001). Furthermore, costs analyses showed that the average total patient cost was less for port access (P < .0005). The differences between endo and classical type suggested that the port access type of surgery is 20% cheaper than the classical one. We may conclude that port access surgery is an acceptable alternative to classical type of surgery, also in complex pathology of the mitral and tricuspid valve.

Surgical Treatment in a Patient with Multiple Systemic Complications of Prosthetic Aortic Valve Endocarditis: Case Report

A 31-year-old woman who had undergone aortic and mitral valve replacement 1 year previously was hospitalized with suspected prosthetic valve endocarditis. Freestyle stentless aortic xenograft was successfully replaced using freestanding total aortic root replacement techniques at the left ventricular outflow tract position, and aorta-to-right coronary artery bypass was also applied with a saphenous vein graft. The patient developed multiple systemic problems during the preoperative and postoperative periods and was successfully treated with intensive interventions. She was discharged at the postoperative fourth month, and the following 28 months were uneventful.

The national animal health monitoring system in Michigan. III. Cost estimates of selected dairy cattle diseases

A study was conducted to estimate costs of major dairy cattle diseases. Sixty ( n=60) of the 6012 dairy herds in Michigan were stratified and selected randomly for participation in the National Animal Health Monitoring System in Michigan. Government and university veterinarians visited each herd once a month for a total period of 12 months. At each visit data on diseases, production, management, finance, treatments, preventive activities, animal events, and any other relevant events were collected. Monthly and annual cost estimates of disease treatments were computed in each herd and stratum. Similarly, monthly and annual estimated preventive costs were estimated. Results were expressed as cost per head and given separately for cows, young stock, and calves. In cows, the most expensive seven disease entities (from most to least) were: (1) clinical mastitis; (2) breeding problems; (3) gastrointestinal problems; (4) birth problems; (5) multiple system problems; (6) lameness; (7) metabolic/nutritional diseases. In terms of estimated annual preventive cost, however, the ranking of the seven disease entities were (from highest to lowest): (1) mastitis; (2) breeding problems; (3) lameness; (4) birth problems; (5) multiple system problems; (6) gastrointestinal disease; (7) metabolic/nutritional problems. In young stock, the most costly diseases were the multiple system problems, breeding problems, respiratory disease, birth problems, gastrointestinal disease, and lameness. In calves, the most costly disease problems were gastrointestinal problems, respiratory diseases, multiple system problems, birth problems, metabolic diseases, and lameness. Methodological issues, as they relate to data collection and estimation of costs as well as suggestions for improving the accuracy of these estimates, are discussed.

Symmetrical widening of the periodontal ligament space in a patient with multiple systemic problems

Progressive systemic sclerosis is an uncommon disease that affects the collagen in multiple organ systems. Characteristic oral manifestations that may complicate dental treatment include limited opening, TMJ dysfunction, mucogingival problems, xerostomia, and pathological resorption of the mandible.

The surgical management of acute occlusion of the superior mesenteric artery.

A study of 103 cases of acute occlusion of the superior mesenteric artery is presented. The relation of site of occlusion to etiology, extent of infarction, and survival following resection and revascularization is described. Included is an analysis of the technical factors contributing to successful revascularization, the specific complications of revascularization, and the application of elective second look operations and angiographic techniques. The persistant high mortality (85% in this series) can probably be reduced but only by advances in these areas along with progress in the more general aspects of management of elderly patients with multiple system problems and failure.