Stepwise Multiple Regression Research Articles

Solid pseudopapillary neoplasms of the pancreas (SPNs): diagnostic accuracy of CT and CT imaging features

PurposeTo summarize the abdominal computed tomography (CT) imaging and clinicopathological data of patients with SPNs of the pancreas and analyze the accuracy of preoperative CT diagnosis and features.Materials and methodsBetween June 2006 and June 2023, CT images of 120 histopathologically proven SPNs in the pancreas were retrospectively reviewed. Fifteen features, including age, sex, and CT-determined features, were included in a multiple stepwise regression analysis. The correlations between features and SPNs, including odds ratios (ORs) and 95% confidence intervals (CIs), were evaluated.ResultsAmong the 120 patients, the diagnostic accuracy of CT was 43.3%. The baseline CT results of patients with a correct diagnosis and misdiagnosis revealed significant differences in sex (P = 0.043), age (P = 0.004), boundary (P = 0.037) and encapsulation (P = 0.002) between the two groups. The preoperative imaging diagnostic accuracy was significantly greater in females than in males (47.9% vs. 25.0%, P = 0.043). The immunohistochemical indices did not significantly differ between the two groups. The results of univariate analysis revealed significant differences in sex (P = 0.048), age (P = 0.014), tumor length (P = 0.023), tumor boundaries (P = 0.039) and capsule type (P = 0.003). The results of multivariate analysis revealed that encapsulation was closely related to the diagnostic accuracy of CT (P = 0.04).ConclusionsThe accuracy of CT in the diagnosis of SPNs is low, but a length‒diameter ratio of the tumor approaching 1.0, encapsulation and clear boundaries are important CT-determined features. The capsule is an independent CT predictor in the diagnosis of SPNs.

Using the Isometric Mid-Thigh Pull to Predict Three-Repetition Maximum Squat Values in Female Athletes.

Prescribing correct training loads in strength- and power-based sports is essential to eliciting performance improvements for athletes. Concurrently, testing strength for the prescription of training loads should be accurate and safe with minimal disruption or fatigue inducement to the athlete. The purpose of this study was to develop a prediction equation in female athletes for the three-repetition maximum (3RM) squat using the isometric mid-thigh pull and basic anthropometric assessments that could be practically applied to support training prescriptions. Female athletes (n = 34) were recruited from netball, volleyball, basketball, and soccer across a spectrum of competitive standards. Each athlete's weight, standing height, seated height, arm span, and biacromial breadth were recorded, and then, on separate occasions separated by at least 48 h, each athlete completed a 3RM squat test and an isometric mid-thigh pull (IMTP) assessment. IMTP variables of peak force and time-dependent force at 50, 100, 150, 200, and 250 ms, as well as anthropometric measures, were used to develop a prediction equation. Squat strength was low-to-moderately correlated with peak force (r = 0.386); force at 100 ms (r = -0.128), 150 ms (r = -0.040), and 200 ms (r = -0.034); standing height (r = 0.294); and biacromial breadth (r = -0.410). Stepwise multiple regression significantly (p < 0.05) explained 26% of the 3RM squat strength variation using peak force and force at 100 ms, resulting in the following equation: Predicted 3RM squat (kg) = [6.102 + (Peak Force × 0.002) - (Force@100 ms × 0.001)]2. The reported equation's predictive accuracy was tested using the same testing protocols following 6-8 weeks of training in a sub-cohort of athletes (n = 14). The predicted and actual recorded 3RM values were not significantly (p = 0.313) different, supporting the use of the IMTP as a test that contributes informative values for use in a predictive equation for training prescription and thus reducing the testing and fatigue-inducing impost on female athletes. However, the 95% CI (-4.18-12.09) indicated predicted values could differ in excess of 10 kg. This difference could lead to an excessive load prescription for an athlete's training program, indicating caution should be taken if using the described method to predict 3RM squat values for programming purposes.

Regional Summed Corneal Refractive Power Changes in Myopic Orthokeratology and Their Relationships With Axial Elongation.

To determine the relationship between regional summed corneal refractive power changes (CRPCs) in myopic orthokeratology and axial elongation. This retrospective study included 70 eyes of 70 patients aged 8 years to 13 years who underwent orthokeratology lens (OK lens) treatment, and all patients underwent regular follow-ups at 1 week, 1 month, 6 months, and 12 months at Zhongshan Ophthalmic Center between January 2019 and May 2021. Axial length (AL) was measured at baseline and 12 months by an IOLmaster 5.0. Refractive error power was measured using cycloplegia. Regional summed CRPCs were calculated by MATLAB software using difference tangential power maps at the sixth month acquired by corneal topography measurements (Medmont E300 Corneal Topographer; Medmont Pty, Victoria, Australia) and defined as changes in corneal refractive power at the sixth month from baseline. The regional summed CRPCs were then subdivided into 4-mm diameter circles, 4- to 5-mm diameter chords, and 5- to 6-mm diameter chords according to the distance from the central of the pupil and into negative, positive, and total according to the values. Pearson correlation, multiple linear regression analysis, and stepwise multiple linear regression analysis were performed to analyze the relationships among these parameters. Axial elongation had a negative relationship with positive regional summed corneal refractive power in the central 4-mm diameter circle and age (r=-0.282, P =0.018; r=-0.473, P <0.001, respectively) and a positive relationship with negative regional summed corneal refractive power in the 5- to 6-mm diameter chord (r=0.361, P =0.002). Stepwise multiple linear regression analysis identified age (standardized β =-0.434, P <0.001) and negative regional summed corneal refractive power in the 5- to 6-mm diameter chord (standardized β =0.305, P =0.004) as factors influencing AL elongation. Negative regional summed corneal refractive power in a 5- to 6-mm diameter chord after OK lens treatment may be an important index for evaluating the control effects of axial elongation.

Trajectory of pelvic floor muscle training adherence in Chinese women with postpartum stress urinary incontinence and its related factors: A longitudinal study

ObjectiveNumerous studies have shown that pelvic floor muscle training (PFMT) adherence in women with postpartum stress urinary incontinence is low and influenced by many factors. However, most previous studies have been cross-sectional studies on PFMT adherence. Neglecting physiological and psychological recovery after childbirth may lead to changes in the adherence to PFMT. This longitudinal study investigated the developmental trajectory of PFMT adherence at 8, 10, and 12 weeks postpartum and the associated factors in China. MethodsA total of 213 women with postnatal stress urinary incontinence who visited the obstetric pelvic floor clinic of a Grade A tertiary specialist maternity hospital in Beijing, China between January 2018 and January 2019 were selected. Compliance levels were measured using PFMT compliance questionnaires at 8, 10, and 12 weeks postpartum. Data on self-efficacy, postpartum social support, and other influencing factors were collected at 12 weeks postpartum. Differences in PFMT compliance scores were analyzed using repeated-measures analysis of variance. Multiple stepwise linear regression analyses were used for multivariate analysis. ResultsThe PFMT compliance scores at 8, 10, and 12 weeks postpartum were 13.47 ​± ​4.42, 10.76 ​± ​4.46, and 7.95 ​± ​5.54, which were at a moderate level and showed a decreasing trend over time. Multiple stepwise line regression analysis showed that the factors influencing compliance with PFMT in women with postpartum stress urinary incontinence were knowledge-attitude-practice of PFMT (t ​= ​4.251, P ​< ​0.001), postpartum social support level (t ​= ​4.304, P ​< ​0.001), and self-efficacy level of PFMT (t ​= ​8.577, P ​< ​0.001). ConclusionThe PFMT compliance of Chinese women with postpartum stress urinary incontinence was moderate, with a downward trend. More effective methods should be chosen to improve women's PFMT compliance based on their situation, such as improving patient self-efficacy, social support, and knowledge-attitude-practice.

Theoretical evidence for a pH-dependent effect of carbonate on the degradation of sulfonamide antibiotics

Carbonate (CO32−/HCO3−) have a significant impact on advanced oxidation processes (AOPs) by consuming reactive free radicals such as HO• to generate CO3•-. However, research on the mechanisms and kinetics of CO3•- remains limited. This study investigates the degradation mechanism and kinetics of sulfonamide antibiotics (SAs) by CO3•- through theoretical calculations. The calculation results revealed that the effect of CO3•- on SAs degradation is pH-dependent due to the dissociable sulfonamide group (-SO2NH-) of SAs in the common water treatment pH range (3–8). The main reaction type of CO3•- with both neutral and anionic molecules of SAs is single electron transfer reaction. Frontier molecular orbital theory (FMO) illustrated that deprotonation of the sulfonamide group of SAs decreases the charge density on the heterocyclic ring, facilitating the electrophilic addition of CO3•-. The second-order rate constants of the neutral and anionic molecules of SAs with CO3•- were calculated as 7.57 × 101∼1.84 × 108 and 1.81 × 107∼7.94 × 109 M−1 s−1, respectively, resulting in an increase in the apparent reaction rate constants with pH. Stepwise multiple linear regression was employed to predict reactivity with anionic sulfonamide antibiotics (SAs−). Two models with outstanding prediction and stability were developed with coefficients of determination R2 of 0.660 and 0.681, respectively. The degradation kinetics simulation indicated that in the UV/H2O2 process in the presence of carbonate, the degradation rate of SAs increased with pH. Furthermore, the contribution of CO3•- to SMX degradation increased while that of HO• decreased. This study highlights the contribution of carbonates to the micropollutant degradation in the UV/H2O2 process as the model, providing theoretical insights into the development of carbonate-based AOPs.

Evaluating Peak Milk Yield as a Predictor for First Lactation 305-Day Milk Yield in Murrah Buffaloes

Background: Peak milk yield is an important early observable trait that holds immense practical significance in dairy farming. It is often utilized to assess the production potential of dairy animals under field conditions. Therefore, the present study aimed to predict the first lactation 305-day milk yield (FL305DMY) based on peak milk yield (PY) and subsequently, compare its efficiency with monthly test-day milk yield (TD) records alone or in combinations. Methods: Data on 350 PY and 3,850 TD records pertaining to first lactation of 350 Murrah buffaloes that calved in between 1993 and 2017 at ICAR-National Dairy Research Institute, Karnal, India were utilized for the investigation. A total of 11 TD records were taken from each animal at an interval of 30 days, starting from 6th day onwards until 305th day of lactation. The prediction of FL305DMY was performed by univariate and stepwise backward multiple linear regression analysis. The efficiency of the prediction equations was evaluated by Coefficient of determination (R2), Akaike Information Criterion (AIC), Bayesian Information Criterion (BIC) and Root Mean Square Error (RMSE). Result: It was observed that the peak milk yield alone could predict the FL305DMY with 64.15% accuracy, which was the highest in univariate linear regression analysis. Furthermore, the regression coefficients and R2 values indicated that mid-lactation monthly test-day milk yield records up to TD-7 could be utilized in conjunction with peak milk yield for early prediction of FL305DMY. The stepwise backward multiple linear regression analysis revealed that the most optimal prediction equation, including peak milk yield as one of the variables, was found to be composed of three variables (PY, TD-4 and TD-7) showed 84.79% R2. The results could be utilized for early selection of genetically superior animals in breeding strategies.

Predictors of Curve of Spee Leveling in Class II Division 1 Malocclusion Treated With Reverse Curve of Spee Archwires: An Observational Study.

Introduction Aligning and leveling is the initial stage of comprehensive fixed orthodontic treatment aimed at minimizing the depth of the curve of Spee (COS). Various techniques exist to decrease the magnitude of the curve. This study investigates the skeletal and dental factors that reduce COS in individuals with minor class II malocclusions receiving nitinol (NiTi) wires with a reverse curve of Spee (RCS). Materials and methods The data for this observational study was collected from a sample of 84 patients who had class II molar relations and were sequentially treated with RCS NiTi wires throughout the initial leveling and aligning phase. All patients with class II molar relationships underwent non-extraction procedures during the leveling phase. The COS was determined using digitalized dental models. Skeletal and dental characteristics that could impact COS were identified and quantified using digital lateral cephalograms and orthopantomograms recorded during the pre-treatment (T1) and post-leveling (T2) stages. After calibrating the radiographs and models, we acquired angular and linear data. The data was categorized based on gender, growth pattern, and initial alignment of the teeth. We analyzed the differences between the groups using an independent t-test and an ANOVA. A paired t-test was used to compare the difference in the dimensional values between (T1) and (T2) points. Following the correlation coefficient tests, the study used stepwise multiple linear regression analysis to assess the predictive value of independent factors on the COS. The results were considered statistically significant at p < 0.05. Results The COS decreased by -1.43 ± 0.68 mm, which is statistically significant (<0.001*). There is no significant difference in COS reduction between the categorical variables. Despite statistically significant differences in the parameters between pre- and post-treatment, the linear correlation between most of the variables and COS reduction ranged from very weak (<0.20) to weak (0.20-0.39). Conclusions The vertical extrusion of lower premolars and molars combined with the intrusion of lower incisors contributed to the reduction of the COS by RCS wires. There is a change in the orientation of the occlusal plane with the flattening of the COS.

Sexuality attitudes and beliefs survey (SABS): validation of the instrument for the polish nursing and midwifery students

The aim of the study is to create a Polish version of the sexuality attitudes and beliefs survey (SABS), to assess its cultural adaptation and psychometric properties and to utilize it to enable a cross-sectional study of the sexual attitudes and beliefs among Poland’s nursing and midwifery students. Non-random network sampling and the adapted SABS v. PL scale were employed for the latter purpose. A total of 570 nursing and midwifery students from two Polish universities completed the questionnaire. Cronbach's alpha coefficient was utilized to measure the internal consistency of the SABS scale, while exploratory factor analysis (EFA) was employed to determine its construct validity. The factors that most affect respondents' sexual attitudes and beliefs were identified through a stepwise multiple regression method and through an econometric model. An exploratory factor analysis of the SABS v. PL scale revealed an adequate fit and confirmed the 4-factor model. The Cronbach's alpha coefficient for SABS v. PL amounted to: α = 0.66. The study's student population had a mean SABS score of 41.65 ± 5.63, while the mean SABS item score varied between 2.55 ± 1.27 and 4.35 ± 1.07. The study's results show that the SABS v. PL questionnaire is a valid and reliable instrument. The work revealed that Polish nursing and midwifery students have attitudes and beliefs which negatively impact their ability to evaluate a person's sexual health concerns and provide relevant health counselling.

Development and validation of a novel vault prediction formula based on structural parameters of the anterior and posterior chambers

BackgroundAccurate prediction of postoperative vault in implantable collamer lens (ICL) implantation is crucial; however, current formulas often fail to account for individual anatomical variations, leading to suboptimal visual outcomes and necessitating improved predictive models. We aimed to verify the prediction accuracy of our new predictive model for vaulting based on anterior and posterior chamber structural parameters.MethodsThis retrospective observational study included 137 patients (240 eyes) who previously underwent ICL surgery. Patients were randomly divided into the model establishment (192 eyes) or validation (48 eyes) groups. Preoperative measurements of the anterior and posterior chamber structures were obtained using Pentacam, CASIA2 anterior segment optical coherence tomography (AS-OCT), ultrasound biomicroscopy, and other devices. Stepwise multiple linear regression analysis was used to evaluate the relationship between the vault and each variable (WL formula). The Friedman test was performed for the vaulting prediction results of the WL, NK (Ver. 3), and KS formulas (Ver. 4) in CASIA2 AS-OCT, as well as the Zhu formula and vault measurements. The proportions of prediction error within ± 250 μm per formula were compared.ResultsThe predicted vault values of the WL, NK, KS, and Zhu formulas and vault measurements were 668.74 ± 162.12, 650.85 ± 248.47, 546.56 ± 128.99, 486.56 ± 210.76, and 716.06 ± 233.84 μm, respectively, with a significant difference (χ2 = 69.883, P = 0.000). Significant differences were also found between the measured vault value and Zhu formula, measured vault value and KS formula, WL formula and Zhu formula, WL formula and KS formula, NK formula and KS formula, and NK formula and Zhu formula (P < 0.001) but not between other groups. The proportions of prediction error within ± 250 μm per formula were as follows: WL formula (81.3%) > NK formula (70.8%) > KS formula (66.7%) > Zhu formula (54.2%).ConclusionsThe WL formula, which considers the complexity of the anterior and posterior chamber structures, demonstrates greater calculation accuracy, compared with the KS (Ver. 4) and Zhu formulas. The proportion of absolute prediction error ≤ 250 μm is higher with the WL formula than with the NK formula (ver. 3). This enhanced predictive capability can improve ICL sizing decisions, thereby increasing the safety and efficacy of ICL implantation surgeries.

Value of gadoxetic acid-enhanced MR imaging for preoperative prediction of future liver regeneration after hemihepatectomy.

Liver resection is currently considered the most effective treatment for patients with liver cancer. To the best of our knowledge, no study has investigated the association between gadoxetic acid-enhanced magnetic resonance imaging (MRI) findings and liver regeneration in patients who underwent hemihepatectomy. We aimed to clarify the relationship between the signal intensity (SI) of the liver parenchyma on gadoxetic acid-enhanced MRI and the degree of liver regeneration in patients who underwent hemihepatectomy. Forty-one patients who underwent gadoxetic acid-enhanced MRI before hemihepatectomy were enrolled. We calculated the liver-to-erector spinae muscle SI ratio (LMR) in the hepatobiliary phase and the precontrast images. ΔLMR was calculated using the following equation: ΔLMR = (LMR in the hepatobiliary phase-LMR in the precontrast image)/LMR in the precontrast image. The preoperative and postoperative remnant liver volumes (LVs) were calculated using CT volumetry. We calculated the resection rate (RR) and liver regeneration index (LRI) using the following formulas: RR = Resected LV/Total LV × 100 and LRI = (postoperative remnant LV-preoperative remnant LV)/preoperative remnant LV × 100. The relationships among LRI, imaging, and clinicopathological factors were analyzed. Univariate analysis showed RR and ΔLMR showed a positive correlation with LRI (ρ = 0.4133, p = 0.0072 and ρ = 0.7773, p < 0.001, respectively). Spleen volume showed a negative correlation with LRI (ρ = -0.3138, p = 0.0486). Stepwise multiple regression analysis showed ΔLMR and RR were independently correlated with LRI (β coefficient = 44.8771, p = 0.0198 and β coefficient = 1.9653, p < 0.001, respectively). ΔLMR may serve as a preoperative predictor of liver regeneration in patients undergoing hemihepatectomy.

초기 읽기 단계의 문단글 읽기이해 관련 요인

Objectives The study aimed to examine the related variables that predict reading comprehension at the end of the first grade. Specifically, it focused on the relationship between reading comprehension and word decoding, reading fluency, vocabulary and syntactic knowledge, as well as the relative contribution of these variables to reading comprehension. Methods Sixty-four first-grade children were participated at the end of the school year. All children had nonverbal intelligence scores of 80 or above. Test were conducted on passage reading comprehension, word decoding, passage reading fluency, expressive vocabulary, semantic relation, and sentence comprehension. Pearson correlation and multiple stepwise regression were used. Results The results showed reading comprehension was positively correlated with expressive vocabulary, semantic relation, and reading fluency. In the stepwise multiple regression analysis, semantic relation, sentence comprehension, expressive vocabulary and reading fluency (but not word decoding) significantly predicted reading comprehension. Conclusions The finding suggests that language abilities including vocabulary and syntactic knowledge play an crucial role of reading comprehension even in early stage of reading development. Furthermore, passage reading fluency, which involves accurate and automatic word recognition rather than just word decoding accuracy, is a critical factor in reading comprehension. In Hanguel, where word decoding accuracy is acquired early and rapidly, linguistic knowledge and reading fluency are considered important variables for assessment and intervention, even in early grades.

Citizens' acceptance of prefabricated housing in China: the role of procedural justice and uncertainty

PurposeThis study explores citizens’ acceptance of prefabricated housing (PH) from the perspective of socio-demographic and psychological factors, aiming to reveal the formation of PH acceptance and realize a sustainable development of PH.Design/methodology/approachThis study proposed hypotheses drawing on procedural justice theory and uncertainty management theory. A survey of 245 respondents was conducted, and the collected data was analyzed in a stepwise multiple regression model. Then, the psychological influencing mechanism was demonstrated using a mediation model.FindingsResults of the data analysis manifested that citizens’ acceptance of PH was influenced by socio-demographic and psychological factors, where psychological factors had more significant effects on acceptance than socio-demographic factors. The psychological mechanism was examined by verifying the mediating role of uncertainty between procedural justice and the acceptance of PH. Furthermore, a scientific strategy for developing PH was proposed based on this empirical study.Originality/valueThis study extends the knowledge of procedural justice theory by investigating people’s acceptance in the PH context. This study is also one of the first studies to unveil the psychological mechanism toward a high-cost product with invisible technological innovation. This study contributes to the literature by introducing uncertainty management theory to a controversial issue, examining and expanding its application in a complicated context. Moreover, results highlight the positive influence of fair processes on controversial issues.

Olfactory Groove Meningiomas and the Association with Postoperative Weight Loss

Abstract Objective Olfactory groove meningiomas (OGM) commonly present with olfactory deficits and compression of the frontal lobes. Given the relationship to dietary behaviors, our objective was to evaluate the relationship between OGMs and postoperative weight loss. Methods Retrospective review of primary resection of meningiomas between 2017 and 2023 at a single institution was conducted. Neurofibromatosis type 2, pregnancy, weight loss medications, or surgeries were excluded. Data collection included preoperative body mass index (preBMI) and postoperative BMI (poBMI) at 3 to 6 and 12 months. Percent BMI change (pcBMI) was calculated by (poBMI − preBMI/preBMI × 100%). IBM SPSS Statistics (Version 27) was used for descriptive statistics and stepwise multiple linear regression. Results Ninety-eight patients met inclusion with a mean age of 57.58 years. Three groups were stratified by location: OGM (n = 15), anterior cranial fossa excluding OGM (ACF; n = 24), and other (OTH; n = 59). Olfactory dysfunction was present in 53.8% of the OGMs. OGM presented with significantly larger lesions (57.25 ± 55.98 mm3) and a higher preBMI (34.58 ± 7.41 kg/m2) than ACF and OTH. A greater pcBMI was seen in OGM at both timepoints (−7.74%, −8.73%). OGM location, tumor volume, and preBMI were found significant on univariate analysis (p &lt; 0.05) and included in multiple linear regression. All regression models were significant (p = 0.001). Location significantly added to the prediction at 3 to 6 and 12 months as well as preBMI at 12 months. In a subanalysis of ACF and OGM, OGM location was significantly associated with negative pcBMI at 3 to 6 and 12 months. Conclusion OGMs are associated with higher preoperative weight and greater weight loss postoperatively compared with other locations.

The influence of parents on children's consciousness of gender equality: a multi-group structural equation modeling approach.

This study aimed to understand the consciousness of gender equality among school-aged children in China and its influencing factors using structural equation modeling to explore the pathways, intensity and group differences among these factors. A cross-sectional survey was conducted using stratified random whole-group sampling of primary school students in grades 1-6 and their parents who met the inclusion and exclusion criteria. In this study, 1,312 valid questionnaires were collected from a total of 1,500 school-aged children in Hunan Province, China (effective response rate of 87.5%). Statistical analysis was conducted using SPSS 26.0 and AMOS 24.0 software. Statistical inference consisted of t-tests, analysis of variance, the LSD test, Pearson correlation analysis, multiple stepwise linear regression analysis and structural equation modeling. School-aged children had the lowest consciousness of gender equality in the area of occupation and relatively higher consciousness in the areas of family and school. Children's age, gender, gender role, parent-child relationship, teacher-student relationship and parents' gender equality consciousness had predictive effects on children's consciousness of gender equality. The structural equation model constructed in this study is applicable to school-aged children of different genders. There was a significant difference in the structural equation modeling for children in different study period groups. In the education process, parents and teachers should attempt to improve their own consciousness of gender equality, integrate the concept of androgynous education, enhance close relationships with children, and adopt appropriate education methods according to the characteristics of different groups of children.

Soluble ST2 Is a Biomarker Associated With Left Ventricular Hypertrophy and Concentric Hypertrophy in Patients With Essential Hypertension.

Elevated soluble stimulating factor 2 (sST2) level is observed in cardiovascular diseases, such as heart failure and acute coronary syndrome, which reflects myocardial fibrosis and hypertrophy, indicating adverse clinical outcomes. However, the association between sST2 and hypertensive heart disease are less understood. This study aimed to determine the relationship of sST2 with left ventricular hypertrophy (LVH) and geometric remodeling in essential hypertension (EH). We enrolled 483 patients (aged 18-80 years; 51.35% female). sST2 measurements and echocardiographic analyses were performed. Stepwise multiple linear regression analysis showed significant associations among sST2, left ventricular (LV) mass, and LV mass index. The prevalence of LVH and concentric hypertrophy (CH) increased with higher sST2 grade levels (P for trend < 0.05). Logistic regression analysis suggested that the highest tertile of sST2 was significantly associated with increased LVH risk, compared with the lowest tertile (multivariate-adjusted odds ratio [OR] of highest group: 6.61; P < 0.001). Similar results were observed in the left ventricular geometric remodeling; the highest tertile of sST2 was significantly associated with increased CH risk (multivariate-adjusted OR of highest group: 5.80; P < 0.001). The receiver operating characteristic analysis results revealed that sST2 had potential predictive value for LVH (area under the curve [AUC]: 0.752, 95% confidence interval [CI]: 0.704-0.800) and CH (AUC: 0.750, 95% CI: 0.699-0.802) in patients with EH. High sST2 level is strongly related to LVH and CH in patients with EH and can be used as a biomarker for the diagnosis and risk assessment of hypertensive heart disease. Trial Number ChiCTR2400082764.

Dry season assessment of carbon storage and emission from upland and riparian soils in the Ganga River basin

Soil organic carbon (C) and nitrogen (N) are profoundly affected by changes in land use and land cover (LULC), especially by farming in riparian zones. The five LULC classes were selected in contiguous order, i.e., undisturbed forest (CALref), conventional agriculture lands (CAL), reservoir riparian zones (RSRZ), river riparian zones (RRZ), and undisturbed riparian zones (RZref) in the Ganga River basin to study the C storage and emission trends at a landscape scale. The riparian soils showed higher moisture, temperature, and bulk density than the upland soils, strongly determining the spatial variations in the CO2 equivalent (CO2e), C:N ratio, and CO2 efflux. Riparian CO2e was more bulk density-dependent, while upland CO2e showed greater dependence on TOC. The C:N ratio showed a higher mean value in the reference soils (CALref and RZref) than in the other soils (P < 0.05). The total nitrogen (TN), total protein (TP), and NH4-N (ammonium‑nitrogen) showed the following trend: RSRZ > CAL > RRZ > RZref > CALref. The stepwise multiple regression models illustrated that soil moisture was the primary regulator of the C:N ratio and CO2 efflux in the upland soils while the temperature in the riparian soils. These intrinsic soil variables resulted in 1.15 to 2.26 times higher CO2 efflux from the cultivated soils (CAL, RSRZ, and RRZ) than from the reference soils. Hence, the present study revealed how agricultural practices tangibly increase the riparian system's carbon footprint while offering unsustainable livelihood options to farmers.

The influence of COVID-19 pandemic on body mass and cardiopulmonary endurance of Chinese adolescents: a longitudinal follow-up study.

With the spread and spread of COVID-19 around the world, youth's learning, lifestyle and health have been greatly affected. Based on the current research, there is no adequate analysis of the development of young people's physique and heart and lung health during COVID-19, and there is a lack of relevant targeted research. The aim of this study was to investigate the changes of BMI and Maximum Oxygen Absorption (VO2max) in 12-14 year old teenagers before and after COVID-19. The BMI, 1,000/800 m running time and associated data related to 29,813 individuals between 2019 and 2022 were collected by cluster sampling, and the changes of BMI Z and VO2max before and after the outbreak were analyzed. Moreover, the relationship between BMI and cardiovascular endurance was analyzed by means of multi-linear stepwise regression. The covariance analysis models indicated that compared with 2019, adolescent weight, BMI, and 1,000/800 m running time showed varying degrees of growth in 2020, while lung capacity decreased. All indicators achieved rapid rebound in 2021 and 2022 (p < 0.01); the one-way analysis of variance models indicated that The BMI Z score and VO2max of adolescents showed growth and decline in 2020, respectively, and achieved rapid recovery and development in 2021 and 2022 (p < 0.01). The results of the multiple linear stepwise regression analysis indicate that, after the years of BMI Z and novel coronavirus infection were included (△R2 = 0.179), adolescents' overweight and obesity were positively correlated with the maximum oxygen uptake (B = 0.643, 95%CI = 0.634 ~ 0.652); There is a negative correlation between weight loss and maximum oxygen uptake (B = -0.510, 95%CI = -0.537~-0.484); The year of novel coronavirus infection was positively correlated with the maximum oxygen uptake of adolescents (B = 0.116, 95%CI = 0.107~0.125). This study shows that the impact of COVID-19 on BMI and heart and lung health in adolescents is significant. Young people of all ages and sexes showed similar developmental trends.

Gravel Mulching Significantly Improves Crop Yield and Water Productivity in Arid and Semi-Arid Regions of Northwest China: Evidence from a Meta-Analysis

In the arid and semi-arid regions of Northwest China, periodic rainfall deficits, high field evaporation, limited freshwater resources, and high irrigation costs restrict crop yield and water productivity (WP). Gravel mulching (GM), a traditional agricultural tillage management practice widely used in arid and semi-arid regions, improves crop yield and WP. However, the combined impacts of GM on crop yield and WP are unclear. This study aimed to examine the effects of GM on crop yield and WP under different factors and to find the most critical regional factors and gravel characteristics that affect crop yield and WP. To quantitatively assess the impact of GM on crop yield and WP, this study performed a meta-analysis, a regression analysis, and a path analysis of 185 yield comparisons and 130 WP comparisons from 30 peer-reviewed scientific reports. This study found that GM significantly increased crop yield and WP by an average of 29.47% and 28.03%, respectively. GM was reported with the highest response percentages (I) of crop yield and WP in regions whose average annual precipitation (AAP) was 200–400 mm, average annual temperature (AAT) was 0–9 °C, and altitude (A) was &gt;1000 m. Overall, AAP, AAT, and A had significant effects on the I of crop yield (p &lt; 0.001), but AAT and A had an insignificant impact on the I of crop WP (p &gt; 0.05). Gravel size (GS), the amount of gravel mulching (AGM), the degree of gravel mulching (DGM), and the gravel mulching thickness (GMT) had a significantly positive impact on crop yield and WP (p &lt; 0.05). The stepwise multiple linear regression analysis results indicated that the primary regional factors influencing yield were AAT and A, contributing 43.14% and 53.09%, respectively. GMT and GS were identified as significant gravel characterization factors impacting yield, contributing 82.63% and 17.37%, respectively. AAP and GMT were the main regional factors and gravel characterization factors affecting WP. Furthermore, the I values for cash crop yield and WP were higher than that for food crops, and moderate fertilization and irrigation would increase the I values of yield and WP. The benefits of GM are strongly correlated with the planting year. This study’s results show that GM generally improves crop yield and WP, although the extent of this impact varies based on different conditions. These findings are not only useful in relation to their direct applicability to other countries worldwide but also due to their potential to provide new ideas for agricultural practices in similar crop-growing environments.

Decoding Cognitive Control and Cognitive Flexibility as Concomitants for Experiential Avoidance in Social Anxiety.

Background and objectives: Avoidance is regarded as a central hallmark of social anxiety. Experiential avoidance is perilous for social anxiety, specifically among university students (young adults). Additionally, cognitive control and cognitive flexibility are crucial components of executive functions for a fulfilling and healthy lifestyle. The current research is a modest attempt to understand how cognitive flexibility and cognitive control affect the emergence of experiential avoidance in social anxiety in young adults. Methods: Using an ex-post facto design, the Social Phobia Inventory was employed to screen university students with social anxiety based on which one hundred and ninety-five were identified. Thereafter, participants completed the standardized measures on experiential avoidance, cognitive control and cognitive flexibility. Results: A stepwise multiple regression analysis was computed wherein the cognitive control predicts an amount of 5% of variance towards experiential avoidance, whereas a 10% of additional variance has been contributed by cognitive flexibility. Interpretation and Conclusions: The statistical outcome indicated that cognitive control is positively associated with experiential avoidance which is a negative correlate to cognitive flexibility among university students. Both also emerged as significant predictors of experiential avoidance and add a cumulative variance of 15% towards the same. This conclusion supports the need for improved and efficient management techniques in counseling and clinical settings.

Valsalva maneuver pressure recovery time is prolonged following spinal cord injury with correlations to autonomically-influenced secondary complications.

This work's purpose was to quantify rapid sympathetic activation in individuals with spinal cord injury (SCI), and to identify associated correlations with symptoms of orthostatic hypotension and common autonomically mediated secondary medical complications. This work was a cross-sectional study of individuals with SCI and uninjured individuals. Symptoms of orthostatic hypotension were recorded using the Composite Autonomic Symptom Score (COMPASS)-31 and Autonomic Dysfunction following SCI (ADFSCI) survey. Histories of secondary complications of SCI were gathered. Rapid sympathetic activation was assessed using pressure recovery time of Valsalva maneuver. Stepwise multiple linear regression models identified contributions to secondary medical complication burden. In total, 48 individuals (24 with SCI, 24 uninjured) underwent testing, with symptoms of orthostatic hypotension higher in those with SCI (COMPASS-31, 3.3 versus 0.6, p < 0.01; ADFSCI, 21.2 versus. 3.2, p < 0.01). Pressure recovery time was prolonged after SCI (7.0s versus. 1.7s, p < 0.01), though poorly correlated with orthostatic symptom severity. Neurological level of injury after SCI influenced pressure recovery time, with higher injury levels associated with more prolonged time. Stepwise multiple linear regression models identified pressure recovery time as the primary explanation for variance in number of urinary tract infections (34%), histories of hospitalizations (12%), and cumulative secondary medical complication burden (24%). In all conditions except time for bowel program, pressure recovery time outperformed current clinical tools for assessing such risk. SCI is associated with impaired rapid sympathetic activation, demonstrated here by prolonged pressure recovery time. Prolonged pressure recovery time after SCI predicts higher risk for autonomically mediated secondary complications, serving as a viable index for more "autonomically complete" injury.