In addressing the multifaceted problem of multiple-input multiple-output (MIMO) detection in wireless communication systems, this work highlights the pressing need for enhanced detection reliability under variable channel conditions and MIMO antenna configurations. We propose a novel method that sets a new standard for deep unfolding in MIMO detection by integrating the iterative conjugate gradient method with Tikhonov regularization, combining the adaptability of modern deep learning techniques with the robustness of classical regularization. Unlike conventional techniques, our strategy treats the Tikhonov regularization parameter, as well as the step size and search direction coefficients of the conjugate gradient (CG) method, as trainable parameters within the deep learning framework. This enables dynamic adjustments based on varying channel conditions and MIMO antenna configurations. Detection performance is significantly improved by the proposed approach across a range of MIMO configurations and channel conditions, consistently achieving lower bit error rate (BER) and normalized minimum mean square error (NMSE) compared to well-known techniques like DetNet and CG. The proposed method has superior performance over CG and other model-based methods, especially with a small number of iterations. Consequently, the simulation results demonstrate the flexibility of the proposed approach, making it a viable choice for MIMO systems with a range of antenna configurations, modulation orders, and different channel conditions.