Multiple Epidermoid Cysts Research Articles

Multiple Epidermoid Cysts Located in the Pineal and Extra cranial Regions Treated by Neuroendoscopy-Case Report-

A 22-year-old woman presented with a rare case of multiple epidermoid cysts located in the pineal and extracranial regions. Magnetic resonance (MR) imaging showed a lesion in the pineal region as hypointense on the T(1)-weighted image and hyperintense on the T(2)-weighted image, without enhancement. Neuroendoscopic treatment was performed under a diagnosis of pineal cyst. However, the cyst wall was too thick to perforate, although third ventriculostomy was performed. Diffusion-weighted MR imaging demonstrated the lesions in the pineal and extracranial regions as marked hyperintensity. The diagnosis was epidermoid cyst. Subsequently, neuroendoscopic treatment of the pineal epidermoid cyst was performed. Careful preoperative diagnosis of epidermoid cysts based on diffusion-weighted MR imaging is required.

Use of a carbon dioxide laser in the treatment of multiple epidermoid cysts

We treated a 41-year-old woman for multiple epidermoid cysts to the face using a carbon dioxide laser. The management and its rationale are discussed.

Growth Hormone-Producing Pituitary Macroadenoma, Multiple Epidermoid Cysts, and Right Atrial Myxoma: An Unusual Case of Carney Complex

Growth Hormone-Producing Pituitary Macroadenoma, Multiple Epidermoid Cysts, and Right Atrial Myxoma: An Unusual Case of Carney Complex

幼児上唇部に発生した多発性・多房性類皮嚢胞の１例

This report describes a very rare case of multiple and multilocular dermoid and epidermoid cysts in the upper lip of a child. Under general anesthesia, exploratory extirpation was carried out via an oral approach. Histological examination revealed a large mass composed of a multilocular dermoid cyst and multiple epidermoid cysts. The dermoid cyst wall had a keratinized squamous epithelial lining extending over sebaceous glands and hair follicles.

Case report: Multiple epidermoid cysts of the testes—The ultrasound appearances

Epidermoid cysts are uncommon tumours of the testes representing approximately 1% of all testicular tumours. Their importance lies in the fact that they are completely benign and can be treated by local excision, thereby saving the patient an orchidectomy. We describe a case in which the patient had multiple epidermoid cysts involving both testes and faced possible bilateral orchidectomy.

Organ Preserving Surgery in Testicular Epidermoid Cysts

Our experience with 18 patients with simple epidermoid cysts of the testis (monodermal teratoma) is reported. In all patients the tumor was enucleated completely and 2 biopsies of the adjacent parenchyma were obtained for exclusion of associated germ cell cancer, scar or carcinoma in situ. There was no evidence of malignancy in any biopsy specimen. Preoperative evaluation included physical examination, testicular sonography, and determination of alpha-fetoprotein and beta-human chorionic gonadotropin levels. Although epidermoid cyst was strongly suggested by sonography, the ultrasonic appearance was not specific and inguinal testicular exploration was required. In 1 patient multiple epidermoid cysts of the right testis were associated with an adult teratoma containing embryonal carcinoma and choriocarcinoma of the left testicle. To our knowledge no similar case has been described in the literature. Based on our results and our experience, we consider tumor enucleation and biopsy of the adjacent parenchyma as adequate treatment for the benign epidermoid cyst. The literature concerning organ sparing surgery in testicular epidermoid cysts is reviewed.

Gastrointestinal polyposis in infancy and childhood

The clinical and pathological features in 12 children with symptomatic gastrointestinal polyposis are presented. Five children with Peutz-Jeghers syndrome all presented with intussusception. Three children with Gardner syndrome presented with multiple large epidermoid cysts of the scalp. The other 4 with juvenile polyposis all presented with anaemia, often associated with growth retardation and extragastrointestinal abnormalities. One of these 4, as well as her mother, had Osler disease with pulmonary arteriovenous malformation. Some degree for overlap in the histology was noted between the polyps in the three conditions, and confusion may arise if only small areas are examined. The histological evolution of small lesions in juvenile polyposis and the surgical observation of friability of adjacent non-polypoid mucosa and association with multiple disorders, local as well as generalised, mechanical as well as inflammatory, suggest these to be the result of non-specific ulceration followed by granulation tissue formation, inflammatory infiltration, and irregular epithelial regeneration.

オトガイ下部にみられた多発性類表皮嚢胞の１例

In the field of Oro-Maxilloface, epidermoid cysts are found in the blottom of the mouth, cheek, lips and tongue, but simultaneous multiple epidermoid cysts are rare.This case was a 40-year-old female who had 3 independent epidermoid cysts in the regio submentalis and her chief complaint was swelling of this place.In Japan, as far as we examined, multiple epidermoid cysts were reported in 6 cases in Oro-Maxillofacial region. However, only 1 case of multiple epidermoid cysts in the regio submentalis was reported.Therefore, we report this rare case.

Idiopathic calcinosis of scrotum

A forty-three-year-old man complained of painless, firm scrotal nodules which had first appeared at age sixteen. These were diagnosed clinically as multiple epidermoid inclusion cysts and were excised. Histologically they were composed of calcified, amorphous, granular material, characteristic of idiopathic calcinosis of the scrotum. This is a rare, benign condition without any recognized underlying metabolic abnormalities. The cause of idiopathic calcinosis of the scrotum is unknown, but we believe it is due to dystrophic calcification of dartoic muscles.

Mycosis Fungoides With Underlying Epidermoid Cysts

The cause of epidermoid cysts is disputed, and many mechanisms have been proposed.^1,2One generally accepted theory is mechanical obstruction of the follicle such as seen in milia, acne cysts, and rarely in association with neoplasms, particularly nevocellular nevi.³Multiple epidermoid cysts of the face and scalp developed in a patient with mycosis fungoides. Histological examination exhibited extensive involvement of the hair follicles with dilation and cyst formation. Although this is an unusual phenomenon, its recognition is important since plaque-stage mycosis fungoides overlying epidermoid cysts may clinically mimic the tumor stage of the disease. The clinical picture may become even more deceptive since these cystic lesions would not be expected to respond to conventional therapy for mycosis fungoides. <h3>Report of a Case</h3> A 53-year-old man was admitted with the complaint of intense pruritus for two months. Twelve years before he had noted a patch of alopecia that slowly

Gardner's syndrome: heredofamilial adenomatosis associated with "soft and hard" fibrous tumors and epidermoid cysts.

Summary and Conclusions Familial polyposis of the colon and rectum appears to be a nonsex-linked hereditary disease, due to a single mutant or pleomorphic gene, which is transmitted as a Mendelian dominant with the expectation that approximately 50 per cent of the off-spring of the affected individual will have the same disease. In recent years the association of familial polyposis with multiple epidermoid cysts and soft or hard fibrous-tissue tumors has been recognized and called Gardner's syndrome. The true syndrome embodies developmental defects of all three germ layers. A case is reported which has all the manifestations of Gardner's syndrome, as well as other interesting features, including a benign, small-bowel tumor, and a congenital anomaly of the anus. Obstructive symptoms occurring during the postoperative period, caused by fibrous adhesions, and the fact that the family history suggested that there had been other similar cases, also, is interesting. Every patient who has multiple epidermoid cysts, osteomata or other soft fibroustissue tumors, regardless of his age, should be investigated for familial polyposis of the colon and rectum, and the inquiry should include all living relatives. Such an approach will lead to earlier detection of persons in whom the disease may not be suspected and proper treatment can be administered in time to lessen the incidence of malignancy and decrease the mortality rate, which is such a disturbing feature of this disease. It is highly desirable that such reliable evidence of polypoid disease of the colon as that encountered in this case report be evaluated properly and that similar cases be reported in the hopes that knowledge of this unusual syndrome can be improved.

FAMILIAL INTESTINAL POLYPOSIS ASSOCIATED WITH FURTHER‘ ABNORMALITIES OF GROWTH

SummaryThe condition of familial polyposis coli associated with “soft” and “hard” tissue tumours is briefly reviewed. A family group suffering from polyposis coli and multiple epidermoid cysts is reported. As far as we are aware, this is the first time this disease entity has been reported in this country.

Multiple epidermoid cysts of the leptomeninges associated with a chromophobe adenoma of the pituitary.

Multiple epidermoid cysts of the leptomeninges associated with a chromophobe adenoma of the pituitary.