Multifunctional Nanocomposites Research Articles

Rational Design of Oil-Resistant and Electrically Conductive Fluorosilicone Rubber Foam Nanocomposites for Sensitive Detectability in Complex Solvent Environments.

Recent years have witnessed the explosive development of highly sensitive smart sensors based on conductive polymer foam materials. However, the design and development of multifunctional polymeric foam composites as smart sensors applied in complex solvent and oil environments remain a critical challenge. Herein, we design and synthesize vinyl-terminated polytrifluoropropylmethylsiloxane through anionic ring-opening polymerization to fabricate fluorosilicone rubber foam (FSiRF) materials with nanoscale wrinkled surfaces and reactive Si-H groups via a green and rapid chemical foaming strategy. Based on the strong adhesion between FSiRF materials and consecutive oxidized ketjen black (OKB) nano-network, multifunctional FSiRF nanocomposites were prepared by a dip-coating strategy followed by fluoroalkylsilane modification. The optimized F-OKB@FSiRF nanocomposites exhibit outstanding mechanical flexibility in wide-temperature range (100 cycle compressions from -20 to 200 °C), structure stability (no detached particles after being immersed into various aqueous solutions for up to 15 days), surface superhydrophobicity (water contact angle of 154° and sliding angle of ∼7°), and tunable electrical conductivity (from 10-5 to 10-2 S m-1). Additionally, benefiting from the combined actions of multiple lines of defense (low surface energy groups, physical barriers, and "shielding effect"), the F-OKB@FSiRF sensor presents excellent anti-swelling property and high sensitivity in monitoring both large-deformation and tiny vibrations generated by knocking the beaker, ultrasonic action, agitating, and sinking objects in weak-polar or nonpolar solvents. This work conceivably provides a chemical strategy for the fabrication of multifunctional polymeric foam nanocomposite materials as smart sensors for broad applications.

Construction of intelligent response gene vector based on MOF/Fe3O4/AuNRs for tumor-targeted gene delivery

Metal-organic frameworks (MOFs) have the potential to efficiently carry cargo due to their excellent porosity and high surface area. Nevertheless, conventional MOFs and their derivatives exhibit low efficiency in transporting nucleic acids and other small molecules, as well as having poor colloidal stability. In this study, a ZIF-90 loaded with iron oxide nanoparticles and Au nanorods was prepared, and then surface-functionalized with polyethyleneimine (PEI) to create a multifunctional nanocomposite (AFZP25k) with pH, photothermal, and magnetic responsiveness. AFZP25k can condense plasmid DNA to form AFZP25k/DNA complexes, with a maximum binding efficiency of 92.85 %. DNA release assay showed significant light and pH responsiveness, with over 80 % cumulative release after 6 h of incubation. When an external magnetic field is applied, the cellular uptake efficiency in HeLa cells reached 81.51 %, with low cytotoxicity and specific distribution. In vitro transfection experiments demonstrated a gene transfection efficiency of 44.77 % in HeLa cells. Following near-infrared irradiation, the uptake efficiency and transfection efficiency of AFZP25k in HeLa cells increased by 21.3 % and 13.59 % respectively. The findings indicate the potential of AFZP25k as an efficient and targeted gene delivery vector in cancer gene therapy.

Metabolic regulating enhanced immunological activating nanocomposites for tumor microenvironment normalization and immunotherapy

The mitochondrial energy metabolic reprogramming of tumors leads to the hypoxic, acidic, and immunosuppressive microenvironment. To regulate the reprogrammed mitochondrial energy metabolism and the abnormal tumor microenvironment (TME) intracellularly and extracellularly, herein, we purposely constructed the metabolic regulating and immunological activating nanocomposites (NCs) formed by the manganese dioxide (MnO2) nanoparticles loaded with lactate oxidase (LOX), dichloroacetic acid (DCA) and SR-717, camouflaged by the cell membrane of tumors. After the NCs targeting to the tumors, the loaded DCA inhibited the glycolysis and triggered the produced pyruvate into mitochondria for further degradation. DCA also reduced the amount of CD39 and CD73, thereby promoting the accumulation of ATP intracellularly. The cascade of MnO2 and LOX catalyzed the lactate to pyruvate together with oxygen for the relief of the hypoxic and immunosuppressive TME. The regulation of the mitochondrial metabolism together with the degradation of lactate contributed to activating the immune cells. Meanwhile, the loaded SR-717 together with the release of Mn2+ activated the cyclic guanosine monophosphate adenosine monophosphate synthase/interferon gene stimulator signaling pathway for efficient antitumor effects and immunotherapy. Taken together, the designed multifunctional nanocomposites realized an effective tumor immunotherapy by regulating the reprogrammed mitochondrial energy metabolism intracellularly, relieving the abnormal TME and activating the innate antitumor immunological effects extracellularly. Our work established an approach to the enhanced immunotherapy by regulating the reprogrammed metabolism for efficient cancer treatment.

Synthesis and Analysis of Magnetic Mg-Zn Nanoferrite Coated by Flavonoids: A Sophisticated Multifunctional Hybrid Nanocomposite for Biomedical Purposes

Synthesis and Analysis of Magnetic Mg-Zn Nanoferrite Coated by Flavonoids: A Sophisticated Multifunctional Hybrid Nanocomposite for Biomedical Purposes

A Multifunctional Nanocomposite Hydrogel Delivery System Based on Dual-Loaded Liposomes for Scarless Wound Healing.

Increased inflammatory responses and oxidative stress at the wound site following skin trauma impair healing. Furthermore, skin scarring places fibroblasts under severe mechanical stress and aggravates pathological fibrosis. A novel liposomal composite hydrogel is engineered for wound microenvironment remodeling, incorporating dual-loaded liposomes into gelatin methacrylate to create a nanocomposite hydrogel. Notably, tetrahydrocurcumin (THC) and hepatocyte growth factor (HGF) are encapsulated in the hydrophobic and hydrophilic layers of liposomes, respectively. The composite hydrogel maintains porous nanoarchitecture, demonstrating sustainable THC and HGF release and enhanced mechanical properties and biocompatibility. This system effectively promotes cell proliferation and angiogenesis and attenuates apoptosis. It decreases the expression of the inflammatory factors by inhibiting the high-mobility group box /receptor for advanced glycation end product/NF-κB (HMGB1/RAGE/NF-κB)pathway and increases macrophage polarization from M1 to M2 in vitro, effectively controlling inflammatory responses. It exhibits remarkable antioxidant properties by scavenging excess reactive oxygen species and free radicals. Most importantly, it effectively prevents scar formation by restraining the transforming growth factor beta (TGF-β)/Smads pathway that downregulates associated fibrotic factors. It demonstrates strong therapeutic effects against inflammation and fibrosis in a rat skin wound model with biosafety, advancing the development of innovative hydrogel-based therapeutic delivery strategies for clinical scarless wound therapy.

Flexible multifunctional magnetic-conductive Janus nanocomposite films towards highly-efficient electromagnetic interference shielding and thermal management

The rapid development of aerospace, intelligent wearable electronics and 5G communications puts forward higher demands for electromagnetic interference (EMI) shielding materials. Herein, the flexible multifunctional magnetic-conductive Janus nanocomposite films with magnetic cobalt carbide nanowires/bacterial cellulose (Co@C NW/BC) blends as the upper side, and conductive Ti3C2Tx MXene as the bottom side are obtained via the layer-by-layer (LBL) vacuum assisted filtration-hot pressing method. The two magnetic and conductive sides endow the Janus nanocomposite films with distinctly different performances in EMI shielding and thermal management. When the electromagnetic waves are incident from Co@C NW/BC side, the films exhibit a high EMI shielding effectiveness (EMI SE) of 49.8 dB with an enhanced microwave absorption (SEA) of 33.9 dB at the ultralow thickness of 43 μm. Meanwhile, the Ti3C2Tx side exhibits improved electrical heating performances with a surface temperature of 120 °C at 6 V voltage, increased photothermal conversion temperature of 77.8 °C upon 2.0 kW/m2 light intensity, as well as excellent thermal stealth properties with a low radiation temperature of 88.4 °C on the 240 °C hot stage. Moreover, the Janus nanocomposite films show a high tensile strength of 80.0 MPa. The resultant Janus nanocomposite films possess great application prospects in highly-efficient EMI shielding and thermal management.

A Se Nanoparticle/MgFe-LDH Composite Nanosheet as a Multifunctional Platform for Osteosarcoma Eradication, Antibacterial and Bone Reconstruction.

Despite advances in treating osteosarcoma, postoperative tumor recurrence, periprosthetic infection, and critical bone defects remain critical concerns. Herein, the growth of selenium nanoparticles (SeNPs) onto MgFe-LDH nanosheets (LDH) is reported to develop a multifunctional nanocomposite (LDH/Se) and further modification of the nanocomposite on a bioactive glass scaffold (BGS) to obtain a versatile platform (BGS@LDH/Se) for comprehensive postoperative osteosarcoma management. The uniform dispersion of negatively charged SeNPs on the LDH surface restrains toxicity-inducing aggregation and inactivation, thus enhancing superoxide dismutase (SOD) activation and superoxide anion radical (·O2 -)-H2O2 conversion. Meanwhile, Fe3+ within the LDH nanosheets can be reduced to Fe2+ by depleting glutathione (GSH) in the tumor microenvironments (TME), which can catalyze H2O2 into highly toxic reactive oxygen species. More importantly, incorporating SeNPs significantly promotes the anti-bacterial and osteogenic properties of BGS@LDH/Se. Thus, the developed BGS@LDH/Se platform can simultaneously inhibit tumor recurrence and periprosthetic infection as well as promote bone regeneration, thus holding great potential for postoperative "one-stop-shop" management of patients who need osteosarcoma resection and scaffold implantation.

Highly Regular Layered Structure via Dual-Spatially-Confined Alignment of Nanosheets Enables High-Performance Nanocomposites.

Assembling ultrathin nanosheets into layered structure represents one promising way to fabricate high-performance nanocomposites. However, how to minimize the internal defects of the layered assemblies to fully exploit the intrinsic mechanical superiority of nanosheets remains challenging. Here, a dual-scale spatially confined strategy for the co-assembly of ultrathin nanosheets with different aspect ratios into a near-perfect layered structure is developed. Large-aspect-ratio (LAR) nanosheets are aligned due to the microscale confined space of a flat microfluidic channel, small-aspect-ratio (SAR) nanosheets are aligned due to the nanoscale confined space between adjacent LAR nanosheets. During this co-assembly process, SAR nanosheets can flatten LAR nanosheets, thus reducing wrinkles and pores of the assemblies. Benefiting from the precise alignment (orientation degree of 90.74%) of different-sized nanosheets, efficient stress transfer between nanosheets and interlayer matrix is achieved, resulting in layered nanocomposites with multiscale mechanical enhancement and superior fatigue durability (100000 bending cycles). The proposed co-assembly strategy can be used to orderly integrate high-quality nanosheets with different sizes or diverse functions toward high-performance or multifunctional nanocomposites.

Growth of nano-porous covalent organic frameworks on graphenic carbon hollow spheres; towards designing advanced multi-functional nanocomposites

For the first time, melamine-based covalent organic frameworks (COFs) were synthesized in situ on the graphenic shells of carbon hollow spheres (CHSs) for achieving a hybrid nanomaterial with unique thermo-mechanical characteristics. To improve the thermal stability of CHS-COF nanostructures (NSs), Zn2+/sodium L-glutamate (ZG) inorganic-organic complexes were loaded in their porosities and interior spaces (denoted as ZG@CHS-COF). The fabricated epoxy nanocomposites illustrated enhanced thermo-mechanical and UV-shielding properties. The tensile strength of the epoxy coatings, filled with CHS-COF and ZG@CHS-COF NSs, increased by 185 and 168 %, respectively, compared to the blank epoxy. DMTA results revealed that the glass transition temperature (Tg) of the epoxy, filled with CHS-COF and ZG@CHS-COF NSs increased around 2.1 and 8.1 °C, respectively. Also, the lower height of tan(δ) peaks (HTP) in the presence of CHS-COF and ZG@CHS-COF NSs illustrated their better interactions with epoxy chains. The highest ash content (≈46.3 %) and superior thermal durability were acquired in the presence of ZG@CHS-COF NSs. TEM results confirmed the better dispersion and distribution of ZG@CHS-COF NSs than CHS ones. The ZG@CHS-COF-filled epoxy coating led to a 71 % reduction in color changes (ΔE) after 3 weeks of UV irradiation.

Silane functionalized cardanol/calcium carbonate epoxy‐reinforced polymer nanocomposites for sustainable microwave absorption applications

AbstractMicrowave absorption properties of epoxy resin/cardanol (ER/C) and epoxy resin/silane functionalized cardanol (ER/SFC) nanocomposites with various percentages of calcium carbonate nanoplatelets (CCNPs) studied in the frequency range of 8–18 GHz. The CCNPs obtained from the mussel shell were reinforced into a cardanol‐toughened ER matrix to mimic the composite structure of the abalone shell. The phase separation between ER, SFC, and CCNPs encapsulated in a polymer matrix was analyzed with SEM, and the presence of a low level of Fe3O4 magnetic impurities of 0.007 emu/g present as shown and verified by XRD and VSM analyses. The nanocomposites with ER/SFC/CCNPs 3 wt.% demonstrate a high surface roughness of 3.467 nm and an enhanced hydrophobicity, as indicated by a high contact angle of 102°. The silanization‐induced localization of CCNPs facilitates a mutually conducive morphology for excellent viscoelastic and microwave absorption properties. The increase in damping factor ratio of approximately 0.85 augments the microwave absorption property and it observed that ER/SFC/CCNPs 3 wt.% nanocomposites show higher reflection loss (RL) of more than 99.9% with RL of −43 dB at 12 GHz. The research aims to fabricate cost‐effective and multifunctional nanocomposites for microwave absorption applications.Highlights Excellent hydrophobicity owing to the surface roughness of 3.467 nm. Maximum contact angle of 102.1° due to the reinforcement of CCNPs and SFC to the epoxy matrix. Efficient microwave attenuation due to the reflection loss of −43 dB. Excellent microwave absorption of 99.99% with a damping factor of 0.85. Higher storage modulus due to the strong inter‐penetrating network of the composite.

Achieving Long‐Range Arbitrary Uniform Alignment of Nanostructures in Magnetic Fields

AbstractFor magnetic field orientation of nonstructures to become a viable method to create high performance multifunctional nanocomposites, it is of paramount importance to develop a method that is easy to implement and that can induce long‐range uniform nanostructural alignment. To overcome this challenge, inspired by low field nuclear magnetic resonance (NMR) technology, a highly uniform, high field strength, and compact magnetic‐field nanostructure orientation methodology is presented for polymeric nanocomposites using a Halbach array, for the first time. Potential new advances are showcased for applications of graphene polymer composites by considering their electro‐thermal and antibacterial properties in highly oriented orthogonal morphologies. The high level of anisotropy induced in the graphene nanocomposites studied stands out through: 1) up to four decades higher electrical conductivities recorded in comparison to their randomly oriented counterparts, at concentrations where the latter show minimal improvements compared to the unfilled polymer; 2) over 1200% improvement in thermal conductivity, 3) antibacterial surfaces at field benchmark levels with lower filler content and with the added versatility of arbitrary orientation of the nanofillers. Overall, the new method and variations thereof can open up new horizons for tailoring nanostructure and performance for virtually all major nanocomposite applications based on graphene and other types of fillers.

Progress in nanocomposites based on starch nanocrystals graft polycaprolactone and modified clay: synthesis, characterization, thermal and antibacterial properties

This research presents a new approach for the fabrication and the characterization of nanocomposites materials, consisting of corn starch nanocrystals, polycaprolactone and, Maghnite–CTA+ (organophilic modified montmorillonite clay intercalated by cetyltrimethylammonium cations). The latter displayed two distinct roles: Maghnite acts as a catalyst for the in situ graft copolymerization through the ring opening of caprolactone with starch macromolecules and, also served at the same time as a nanofiller. The structural of the obtained materials was identified by FT-IR, Moreover, the dispersion state of Maghnite particles was examined by XRD, SEM, TEM, TGA, and DLS (particle size), thermogravimetric results indicate that the incorporation of the Maghnite organophilic in to the copolymer (SNCs-g-PCL) enhanced the thermal properties of the nanocomposites. Additionally, the nanocomposites show significant behavior against gram positive bacterial (Bacillus cereus, Staphylococcus aureus, Klebsiella pneumonia) and gram negative bacterial (Pseudomonas aeruginosa,). The synergistic effects of SNC, PCL, and Maghnite–CTA+ contribute to the development of multifunctional nanocomposites, positioning them for potential applications in areas such as packaging and biomedical materials. This research bridges the gap between renewable resources and advanced materials, offering a sustainable solution with versatile functionalities . These findings underscore the potential of the SNCs-g-PCL/Mag-CTA+ nanocomposites as environmental friendly materials with improved thermal and antimicrobial properties.

Self-assembled multifunctional Prussian blue analogues nanocomposite for MRI-guided multimodal therapy for breast cancer

Integration of multimodal imaging and therapies into one nanoplatform holds great promise to overcome the drawbacks of conventional single-modal cancer therapy. Designing multifunctional nanocomposite by self-assembled strategy with integration of various functional components into one platform is promising for effective breast cancer therapy. Herein, a L-arginine embedded Prussian blue analogue@polypyrrole@manganese oxide (PBA@PPy@MnO2) multifunctional nanocomposite was constructed by a facile self-assembled method, which could be used as an effective nanoplatform for magnetic resonance imaging (MRI) guided multimodal therapy for breast cancer. Various properties such as enhanced MRI and catalytic capacity from PBA and MnO2, photothermal conversion performance from PPy, and NO generation capacity from Arg were integrated into one nanocomposite. In vitro and vivo experiments, satisfactory anti-cancer efficiency was observed in PBA@PPy@MnO2@Arg nanoplatform under near-infrared irradiation (NIR) due to the combined effect between chemodynamic therapy (CDT), photothermal therapy (PTT), and gas therapy (GT). This work will pave a new avenue for the construction of multifunctional nanoplatforms and overcome the inherit poor photothermal and MRI activities limitations of Prussian blue analogue in biomedical field.

Nanocomposite based on hydroxyapatite and boron nitride nanostructures containing collagen and tannic acid ameliorates the mechanical strengthening and tumor therapy

The increase in life expectancy has led to a concerning decline in the body's functional capacity, particularly in bone health, where decreased resistance and increased fracture susceptibility pose significant challenges in orthopedics. While traditional bone grafting methods have drawbacks, synthetic materials, particularly hydroxyapatite (HA), offer promising alternatives due to their biocompatibility and osteoconductive properties. However, HA's mechanical limitations necessitate reinforcement, with boron nitride nanostructures emerging as a particularly effective option, enhancing fracture resistance and combining HA with collagen, further mimicking natural bone composition, offering several benefits. Moreover, crosslinking agents like tannic acid (TA) improve collagen's stability and introduce therapeutic benefits. Therefore, the present work aimed to synthesize an innovative nanocomposite formed by hydroxyapatite, boron nitride nanostructures, collagen, and tannic acid. The nanocomposites obtained were characterized using X-ray diffraction (XRD), Fourier transform infrared spectroscopy (FTIR), thermogravimetry (TGA), elemental analysis of carbon, hydrogen, and nitrogen (CHN), and scanning electron microscopy (SEM). Mechanical tests of Vickers hardness, nanoindentation, tensile, and DMA demonstrated an increase in the mechanical resistance of the nanocomposites, thus corroborating their promising character. A controlled drug release test showed that the system could be used for antibiotic (ciprofloxacin) delivery, further expanding its function. Biological cell viability assays reported that the system is not toxic to healthy cells and is harmful to tumor cells, thus demonstrating the antitumor nature of TA. Therefore, integrating HA, BN nanostructures, collagen, and TA into a multifunctional nanocomposite, a novel approach in orthopedic biomaterial design is offered as a promising solution to address various bone-related challenges.

Construction of bio-inspired multifunctional triple-layered nanocomposite enhances the cell adhesion and treatment of wound repair

Construction of bio-inspired multifunctional triple-layered nanocomposite enhances the cell adhesion and treatment of wound repair

Synthesis of organic-inorganic hybrid nanocomposites modified by catalase-like catalytic sites for the controlling of kiwifruit bacterial canker.

Kiwifruit bacterial canker, caused by Pseudomonas syringae pv. Actinidiae (Psa), is one of the most important diseases in kiwifruit, creating huge economic losses to kiwifruit-growing countries around the world. Metal-based nanomaterials offer a promising alternative strategy to combat plant diseases induced by bacterial infection. However, it is still challenging to design highly active nanomaterials for controlling kiwifruit bacterial canker. Here, a novel multifunctional nanocomposite (ZnO@PDA-Mn) is designed that integrates the antibacterial activity of zinc oxide nanoparticles (ZnO NPs) with the plant reactive oxygen species scavenging ability of catalase (CAT) enzyme-like active sites through introducing manganese modified polydopamine (PDA) coating. The results reveal that ZnO@PDA-Mn nanocomposites can efficiently catalyze the conversion of H2O2 to O2 and H2O to achieve excellent CAT-like activity. In vitro experiments demonstrate that ZnO@PDA-Mn nanocomposites maintain the antibacterial activity of ZnO NPs and induce significant damage to bacterial cell membranes. Importantly, ZnO@PDA-Mn nanocomposites display outstanding curative and protective efficiencies of 47.7% and 53.8% at a dose of 200 μg mL-1 against Psa in vivo, which are superior to those of zinc thiozole (20.6% and 8.8%) and ZnO (38.7% and 33.8%). The nanocomposites offer improved in vivo control efficacy through direct bactericidal effects and decreasing oxidative damage in plants induced by bacterial infection. Our research underscores the potential of nanocomposites containing CAT-like active sites in plant protection, offering a promising strategy for sustainable disease management in agriculture.

Development of multifunctional graphene-based nanocomposites with synergistic effects of chemical and physical interactions

In this work, two types of graphene-based polyamide 66 (PA66) nanocomposites were prepared by in-situ polymerization. The effect of the surface functional groups of graphene oxide (GO) and the chemically modified GO (GO-DDA) on the structure and the properties of the nanocomposites were investigated. The nanocomposites achieved excellent enhancement in the properties. Compared to PA66/GO nanocomposites, PA66/GO-DDA nanocomposite showed higher Young’s modulus, tensile strength and thermal decomposition temperature at all the filler content. For example, at the filler content of 0.3 wt%, PA66/GO-DDA nanocomposite exhibited 92 % increase in the Young’s modulus, while PA66/GO nanocomposite exhibited 42 % increase. The thermal decomposition temperature was improved from 357 °C to 388 °C and to 383 °C by the incorporation of only 0.5 wt% of GO-DDA and GO, respectively. These results indicate the synergy reinforcement effect brought by the chemical interactions and the physical interactions between PA66 and GO-DDA.

Aβ42 and ROS dual-targeted multifunctional nanocomposite for combination therapy of Alzheimer’s disease

Amyloid-β (Aβ) readily misfolds into neurotoxic aggregates, generating high levels of reactive oxygen species (ROS), leading to progressive oxidative damage and ultimately cell death. Therefore, simultaneous inhibition of Aβ aggregation and scavenging of ROS may be a promising therapeutic strategy to alleviate Alzheimer’s disease pathology. Based on the previously developed antibody 1F12 that targets all forms of Aβ42, we developed an Aβ42 and ROS dual-targeting nanocomposite using biodegradable mesoporous silica nanoparticles as carriers to load ultra-small cerium oxide nanocrystals (bMSNs@Ce-1F12). By modifying the brain-targeted rabies virus glycoprotein 29 (RVG29-bMSNs@Ce-1F12), this intelligent nanocomposite can efficiently target brain Aβ-rich regions. Combined with peripheral and central nervous system treatments, RVG29-bMSNs@Ce-1F12 can significantly alleviate AD symptoms by inhibiting Aβ42 misfolding, accelerating Aβ42 clearance, and scavenging ROS. Furthermore, this synergistic effect of ROS scavenging and Aβ clearance exhibited by this Aβ42 and ROS dual-targeted strategy also reduced the burden of hyperphosphorylated tau, alleviated glial cell activation, and ultimately improved cognitive function in APP/PS1 mice. Our findings indicate that RVG29-bMSNs@Ce-1F12 is a promising nanodrug that can facilitate multi-target treatment of AD.

Multifunctional Antimonene-Silver Nanocomposites for Ultra-Multi-Mode and Multi-Analyte Sensing, Parallel and Batch Logic Computing, Long-Text Information Protection.

To simulate life's emergent functions, mining the multiple sensing capabilities of nanosystems, and digitizing networks of transduction signals and molecular interactions, is an ongoing endeavor. Here, multifunctional antimonene-silver nanocomposites (AM-Ag NCs) are synthesized facilely and fused for molecular sensing and digitization applications (including ultra-multi-mode and multi-analyte sensing, parallel and batch logic computing, long-text information protection). By mixing surfactant, AM, Ag+ and Sodium borohydride (NaBH4) at room temperature for 5min, the resulting NCs are comprised of Ag nanoparticles scattered within AM nanosheets and protected by the surfactant. Interestingly, AM-Ag NCs exhibit ultra-multi-mode sensing ability for multiplex metal ions (Hg2+, Fe3+, or Al3+), which significantly improved selectivity (≈2 times) and sensitivity (≈400 times) when analyzing the combined channels. Moreover, multiple sensing capabilities of AM-Ag NCs enable diverse batch and parallel molecular logic computations (including advanced cascaded logic circuits). Ultra-multi-mode selective patterns of AM-Ag NCs to 18 kinds of metal ions can be converted into a series of binary strings by setting the thresholds, and realized high-density, long-text information protection for the first time. This study provides new ideas and paradigms for the preparation and multi-purpose application of 2D nanocomposites, but also offers new directions for the fusion of molecular sensing and informatization.

Multifunctional Nanocomposites of Bismuth@porphyrin-Based Covalent–Organic Polymers with a Core–Shell Structure for Tumor Treatment

Multifunctional Nanocomposites of Bismuth@porphyrin-Based Covalent–Organic Polymers with a Core–Shell Structure for Tumor Treatment