Multidetector Computed Tomography Angiography Research Articles

El informe radiológico en la enfermedad vascular torácica urgente

Urgent thoracic vascular conditions comprise a group of entities with high mortality. This paper will focus on acute aortic disease, pulmonary embolisms, and hemoptysis, conditions in which radiology plays a fundamental role in the diagnosis and in urgent decision making about treatment. Multidetector CT angiography is the imaging technique of choice. We propose a model for structured radiology reports to organize the information included, facilitate the synthesis of the findings, and foster clear communication with professionals of other specialties.

Pleuropulmonary MDCT Findings: Comparison between Children with Pulmonary Vein Stenosis and Prematurity-Related Lung Disease.

Purpose: To retrospectively compare the pleuropulmonary MDCT findings in children with pulmonary vein stenosis (PVS) and prematurity-related lung disease (PLD). Materials and Methods: All consecutive infants and young children (≤18 years old) who underwent thoracic MDCT studies from July 2004 to November 2021 were categorized into two groups—children with PVS (Group 1) and children with PLD without PVS (Group 2). Two pediatric radiologists independently evaluated thoracic MDCT studies for the presence of pleuropulmonary abnormalities as follows—(1) in the lung (ground-glass opacity (GGO), triangular/linear plaque-like opacity (TLO), consolidation, nodule, mass, cyst(s), interlobular septal thickening, and fibrosis); (2) in the airway (bronchial wall thickening and bronchiectasis); and (3) in the pleura (thickening, effusion, and pneumothorax). Interobserver agreement between the two reviewers was evaluated with the Kappa statistic. Results: There were a total of 103 pediatric patients (60 males (58.3%) and 43 females (41.7%); mean age, 1.7 years; range, 2 days–7 years). Among these 103 patients, 49 patients (47.6%) comprised Group 1 and the remaining 54 patients (52.4%) comprised Group 2. In Group 1, the observed pleuropulmonary MDCT abnormalities were—pleural thickening (44/49; 90%), GGO (39/49; 80%), septal thickening (39/49; 80%), consolidation (4/49; 8%), and pleural effusion (1/49; 2%). The pleuropulmonary MDCT abnormalities seen in Group 2 were—GGO (45/54; 83%), TLO (43/54; 80%), bronchial wall thickening (33/54; 61%), bronchiectasis (30/54; 56%), cyst(s) (5/54; 9%), pleural thickening (2/54; 4%), and pleural effusion (2/54; 4%). Septal thickening and pleural thickening were significantly more common in pediatric patients with PVS (Group 1) (p < 0.001). TLO, bronchial wall thickening, and bronchiectasis were significantly more frequent in pediatric patients with PLD without PVS (Group 2) (p < 0.001). There was high interobserver kappa agreement between the two independent reviewers for detecting pleuropulmonary abnormalities on thoracic MDCT angiography studies (k = 0.99). Conclusion: Pleuropulmonary abnormalities seen on thoracic MDCT can be helpful for distinguishing PVS from PLD in children. Specifically, the presence of septal thickening and pleural thickening raises the possibility of PVS, whereas the presence of TLO, bronchial wall thickening and bronchiectasis suggests PLD in the pediatric population.

Total cholesterol/high-density lipoprotein cholesterol and low-density lipoprotein cholesterol/high-density lipoprotein cholesterol as predictors of coronary artery calcification assessed by multidetector computed tomography coronary angiography.

Coronary artery calcification (CAC) is an important marker of total burden of coronary atherosclerosis. Furthermore, it is a measure of subclinical atherosclerotic disease that correlates well with the cardiovascular risk. The aim of our study was to determine the role of the different lipid parameters in prediction of calcification in coronary arteries using multidetector computed tomography (MDCT). This study was conducted on 120 patients presenting to the clinic with typical or atypical chest pain or dyspnea on exertion, or equivocal stress test results along with standard cardiac risk factors; they all underwent computed tomography (CT) coronary angiography. A total calcium score was determined by summing individual lesion scores from each of our anatomic sites: left main (LM), left anterior descending (LAD), left circumflex (LCX), and right coronary artery (RCA). The amount of calcium present in the coronary arteries was scored according to Agatston score, and patients were divided into 2 groups based on absence (group I) and presence (group II) of CAC. Clinical characteristics, lipid ratios, and a full blood count were calculated and compared between both groups. Mean and standard deviation (SD) for age of group I was 52.4 ± 8.4 years, while that of group II was 53.7 ± 7.9 (P > 0.005). Patients in group II had a higher total cholesterol (TC), low-density lipoprotein (LDL), TC/high-density lipoprotein cholesterol (HDL-C) and LDL/HDL-C ratio, and lower HDL levels. TC/HDL ratio and LDL/HDL ratio were found to be good predictors of calcium using a regression analysis model. Finally, at a cut-off value of ≥ 3.108, LDL/HDL ratio showed a sensitivity of 58.8% and specificity of 84.6% in prediction of coronary calcium, while TC/HDL ratio ≥ 4.742 showed a sensitivity of 60.3% and specificity of 88.5%. Amongst the different lipid parameters, TC/HDL-C and LDL/HDL ratio were found to be good predictors of presence of CAC in coronary arteries.

Imaging Evaluation of Mesenteric Ischemia: Is There a Golden Period for This Entity?

Background.The study was aimed at assessing the role of ultrasonography and multidetector computed tomography angiography in evaluating patients with suspected mesenteric ischemia, as well as assessing the effect of the time from presentation to management on mortality and morbidity.&#x0D; Materials and Methods. Patients with clinically suspected mesenteric ischemia underwent Doppler ultrasound and contrast-enhanced computed tomography. On ultrasonography, we assessed any filling defect in the superior mesenteric artery/vein, narrowing or occlusion of the proximal superior mesenteric artery, ascites, bowel wall thickening, and pneumatosis/portal venous gas. Computed tomography angiography was performed looking for any filling defect in the superior mesenteric artery/vein, superior mesenteric artery/vein calibre, bowel wall thickening, calibre and enhancement and pneumatosis/portal vein gas. Most of our patients underwent emergency surgery and the findings correlated with imaging. All the patients were divided into Group A (n=30) and Group B (n=17) based on the time from presentation to management: within 48 hours of presentation and 48 hours after presentation, respectively.&#x0D; Results. On computed tomography scan, mesenteric vascular involvement was seen in 27 (55%) patients, mesenteric/intestinal twist was observed in 12 (25%) patients, and non-occlusive mesenteric ischemia was found in 6% of patients. The computed tomography findings were found to have a sensitivity of 86%, a specificity of 94% and an accuracy of 90% in cases of mesenteric ischemia. Among 35 patients operated on, those presenting within 48 hours, had a significantly less mortality (63%) in comparison to those presenting after 48 hours (90%).&#x0D; Conclusions. Clinical, laboratory and ultrasound features are non-specific in diagnosing mesenteric ischemia. Computed tomography angiography is a sine qua non in mesenteric ischemia diagnosis. Patients with venous ischemia respond well to conservative management. Early intervention within the first 48 hours is associated with better prognosis.

Head-to-head comparison of ventilation/perfusion single photon emission computed tomography/computed tomography and multidetector computed tomography angiography for the detection of acute pulmonary embolism in clinical practice.

Computed tomography angiography (CTA) and ventilation/perfusion (V/Q) single photon emission computed tomography/CT (SPECT/CT) images have been widely used to detect PE, but few studies have performed a direct comparison between them. We aimed to evaluate the performance of these tests in the same group of patients, selected from the routine practice of a general hospital. Patients with suspected acute PE were prospectively submitted to CTA and V/Q SPECT/CT. General radiologists and nuclear physicians, respectively, interpreted the images. Data regarding age, sex, time between examinations, symptoms, and Wells score were also recorded. The final diagnosis was decided through a consensus among the clinicians, taking into account clinical, laboratory, follow-up, and all imaging procedures data. Twenty-eight patients (15 male, 13 female, and median age of 51.5years) were studied. Median duration of the onset of symptoms was 4 (1-14)days, and the median Wells score was 3.5 (1.5-6). Sensitivity, specificity, positive and negative predictive values, and accuracy were 84.6%, 80.0%, 78.6%, 85.7%, and 82.1% for V/Q SPECT/CT, and 46.1%, 100%, 100%, 68.2%, and 75.0% for CTA. The overall agreement between the methods was 57.1%. Of the 22 patients with negative CTA, 10 (45.4%) had positives V/Q SPECT/CT and seven of them classified as true positives. Our results suggest that V/Q SPECT/CT is more sensitive and accurate than CTA when interpreted by general radiologists and nuclear medicine physicians.

Juxtaposition of atrial appendages: Evaluation of cardiovascular morphology and associated anomalies on multidetector computed tomography angiography.

To evaluate the morphology and associated cardiovascular abnormalities in patients with juxtaposition of atrial appendages (JAA) on multidetector computed tomography (MDCT) angiography. We performed the retrospective study at a tertiary referral center to identify patients diagnosed with JAA on MDCT angiography using dual-source CT scanner between January 2014 and April 2021. The various imaging abnormalities evaluated included the type of JAA, morphological and positional classification of JAA, atrial situs, cardiac position, atrioventricular and ventriculoarterial connections, great vessel relationship, and other associated cardiovascular anomalies. We identified 129 patients with JAA. Left-sided juxtaposition was seen in 124 (96.1%) patients while right-sided juxtaposition was seen in 5 (3.9%) patients. Among patients with left-sided juxtaposition, frequent cardiovascular associations included outflow tract malformations (100%), hypoplastic right ventricle (40.3%), tricuspid atresia (32.2%), and right-sided heart (19.4%). The most frequent outflow tract malformation was double outlet right ventricle (DORV; 60.5%) followed by transposition of great arteries (20.1%) and transposed aorta with pulmonary atresia (18.5%). In patients with right-sided juxtaposition, outflow tract malformation was seen in three (60%) patients with one (20%) patient each showing DORV, transposed aorta with pulmonary atresia, and tetralogy of Fallot, respectively. The identification of JAA on MDCT angiography suggests coexistence of various complex congenital heart diseases, especially outflow tract malformations. A meticulous search is imperative to identify this anomaly before interventional or surgical procedures to avoid complications.

Oral Inflammatory Burden and Carotid Atherosclerosis Among Stroke Patients

IntroductionThis study aimed to test the hypothesis that oral inflammatory burden (OIB) is independently associated with the carotid atherosclerotic burden (CAB) among individuals with ischemic stroke (IS) or transient ischemic attack (TIA). MethodsThis cross-sectional observational study included 240 hospital patients with the diagnosis of IS or TIA. The main exposures were apical periodontitis (AP), root canal treatment (RCT), and crestal alveolar (periodontal) bone loss (BL), and the main outcome was the CAB. Exposure and outcome variables were measured through a head and neck multidetector computed tomography angiography and CAB was dichotomized in <50% and ≥50% vessel occlusion. OIB scored as a composite measure of the endodontic and periodontal disease exposure. Hospital health records provided information on sociodemographic and medical covariates. Prevalence ratios (PRs) were calculated through Poisson regression models, estimating the relationship between the oral exposures and CAB, with = 5%. ResultsMean age was 62.15 ± 13.1 years, with 56.7% men. Univariate analyses showed that AP ≥2 (PR = 1.83; 95% confidence interval [CI], 1.05–3.17) and endodontic burden (EB) (AP and/or RCT ≥ 2) (PR = 1.98; 95% CI, 1.13–3.47) were associated with CAB ≥50%. Multivariate models, adjusted for sociodemographic and medical covariates, revealed that pooled periodontal and endodontic parameters (OIB = BL ≥ 5 mm and EB ≥ 2) were independently associated with CAB ≥ 50% (PR = 2.47; 95% CI, 1.04–5.87). ConclusionA higher OIB was independently associated with increased levels of CAB among hospital patients with IS or TIA. The combination of endodontic and periodontal parameters strengthened the observed association and should be evaluated in future studies on the relationship between oral health and cardiovascular outcomes.

320 cardiac MDCT angiography in preoperative assessment of TOF and its variants: Does it worth it?

BackgroundTetralogy of Fallot is the most common cyanotic congenital heart disease encountering a large spectrum of anatomical presentations with differing surgical approaches, and long-term outcomes ranging from ventricular septal defect with limited aortic overriding and mild pulmonary obstruction to a critical form of VSD and pulmonary atresia. TOF variants include PA/VSD, TOF/CAVC, TOF/DORV and TOF with absent pulmonary valve. Also, it may be accompanied with many associated intracardiac and extracardiac anomalies that may be of value when imaging and planning the surgical procedure.ResultsOur study included 22 cases of classic TOF, 18 with PA/VSD (12 were of type A, 5 were of type B and 1 was of type C), 3 with TOF/CAVC and 7 TOF/DORV. Sub-valvular RVOTO was detected in 94% of patients. A statistically significant difference was depicted between Echocardiography and MDCT in detecting supravalvular RVOTO, however no statistically significant difference was found in sub-valvular and valvular RVOTO detection. MDCT could efficiently characterize pulmonary arterial tree with statistically significant difference between both Echocardiography and MDCT in assessment of main, right and left pulmonary arteries with P value = 0.036,0.014 and 0.023 respectively. With calculation of Mc-Goon ratio in all patients, it was favorable (> 1.2) in 33 patients (66%). MDCT entailed 19 patients with PDA versus 15 depicted by Echocardiography and 25 MAPCAs per 11patients compared 8 MAPCAs per 7 patients detected by Echocardiography. Right sided aortic arch was found in 10 patients and 24 patients showed abnormal branching pattern. Coronary artery abnormalities were identified in eight patients. MDCT showed 100% sensitivity and 100% specificity in depicting aortic, coronary and other associated extracardiac vascular anomalies.ConclusionMDCT offers comprehensive anatomical assessment of TOF, and its variants providing superiority over echocardiography and comparable results to cardiac catherization with 100% sensitivity and specificity in evaluation of associated extracardiac vascular anomalies as well as pulmonary arteries characterization. It is worth using MDCT routinely in combination with echocardiography for the preoperative assessment of TOF and its variants representing a less invasive option than conventional catherization with lower radiation exposure.

An Egyptian study to assess the accuracy and reliability of CAD-RADS CT coronary angiography algorithm in the evaluation of coronary artery disease

BackgroundMultidetector computed tomography angiography (MDCT) is a non-invasive examination for coronary artery disease. Coronary artery disease reporting and data system (CAD-RADS) is a structured reporting system that successfully facilitated communication with clinicians. Our study aimed to assess the accuracy as well as the agreement of the CAD-RADS system with the conventional angiography results.Results48 patients were enrolled in this prospective study, all patients underwent MDCT coronary angiography and conventional coronary artery angiography. An excellent inter method agreement between coronary CT angiography (CCTA) and conventional coronary angiography was noted for the left main trunk (LMT) with k = 1 (p < 0.001). An excellent inter method agreement was found for the proximal, mid- and distal segments of the left anterior descending artery (LAD) and the second diagonal segment, with k = 1, 0.842 0.886 and 0.886, respectively (p < 0.001). A good agreement was noted at the first diagonal segment with k = 0.765 (p < 0.001). An excellent inter-method agreement was found for the proximal, mid- and distal segments of the left circumflex artery (LCx) and the obtuse marginal branch, with k = 0.838, 0.846, 1 and 0.846, respectively (p < 0.001). An excellent agreement was found for the proximal and mid-segments of the right coronary artery (RCA) and the posterior descending artery, with k = 1 for all segments (p < 0.001), yet a good agreement was noted at its distal segment with k = 0.782 (p < 0.001). The overall per-patient sensitivity, specificity and accuracy of the CT coronary angiography were 92.9%, 90% and 91.7% respectively.ConclusionsThe CAD-RADS algorithm and invasive coronary angiography agreed perfectly; thus, CT coronary angiography can be used as the first screening test and the invasive coronary angiography can be spared for cases requiring intervention.

Massive hemoptysis treated with embolization of an ectopic bronchial artery arising from the right thyrocervical trunk: a case report

BackgroundEctopic bronchial artery and non-bronchial systemic arteries may be the culprit vessels of hemoptysis. The main cause of clinical failure of bronchial artery embolization is incomplete embolization caused by the misidentification of the culprit arteries by conventional angiography. Multidetector computed tomography angiography is useful for visualizing the culprit arteries.Case presentationAn 82-year-old man was admitted with hemoptysis. Preprocedural multidetector computed tomography angiography revealed an ectopic bronchial artery branching from the right thyrocervical trunk. Superselective embolization of the ectopic bronchial artery was performed using gelatin sponge particles and metallic coils. Hemoptysis was controlled by this procedure without any associated complications.ConclusionsEctopic bronchial arteries originating from the thyrocervical trunk are rare. Preprocedural multidetector computed tomography angiography is useful for visualizing the culprit arteries of hemoptysis, especially if a patient has an ectopic bronchial artery or an ectopic non-bronchial systemic artery.

Comparison of low-dose contrast computed tomography angiography findings with surgical results in living kidney donors

Aim: To analyze the image quality and diagnostic performance of CT angiography using low dose (60 ml) contrast medium for living kidney donors and compare with surgical results.&#x0D; Material and Method: Angiographic findings of 81 renal donor candidates in 128-slice MDCT were evaluated by two independent radiologists in terms of renal artery number, early bifurcation, renal vein variations, pelvicalyceal system and ureter variations. Results were compared with intraoperative findings. The image quality, diagnostic performance and interobserver agreement of MDCT obtained with low dose contrast material were analyzed.&#x0D; Results: The mean age of the 81 living kidney donors included in the study was 49±12 (24-68) years. Left nephrectomy was performed in 71% (n=64) and right nephrectomy in 29% (n=17) of the donors. Intraoperative accessory arteries were detected in 22.2% (n:18) of the donors. The specificity, sensitivity, and accuracy for detecting accessory artery variation in MDCT were 100%, 88.9%, and 97.5%, respectively. Early bifurcation was observed in 21% (n=17) of the donors. Specificity, sensitivity and accuracy for early bifurcation detection were 98.4%, 94.1% and 97.5%, respectively. Renal vein variation was detected in 12.3% (n=10) of the donors. Specificity, sensitivity, and accuracy for renal vein variation detection were 100%. Variations of the pelvicalyceal system and ureter were observed in 3.7% (n=3) of the donors. The specificity, sensitivity, and accuracy for detecting pelvicalyceal system and ureteral variations were 100%. Interobserver agreement was excellent in detecting variations of accessory arteries, renal venous anomalies, pelvicalyceal system and ureters by MDCT (kappa: 1,000; p&lt; 0.001). It was higher in early bifurcation detection (kappa: 0.853; p&lt; 0.001).&#x0D; Conclusion: MDCT angiography with a lower dose of iodine contrast at 60 mL in kidney donors is sufficient to detect vascular anomalies and provide anatomical information. It is possible to reduce the contrast agent dose in CTA without affecting the preoperative evaluation.

MDCT Imaging of Non-Traumatic Thoracic Aortic Emergencies and Its Impact on Diagnosis and Management-A Reappraisal.

Non-traumatic thoracic aorta emergencies are associated with significant morbidity and mortality. Diseases of the intimomedial layers (aortic dissection and variants) have been grouped under the common term of acute aortic syndrome because they are life-threatening conditions clinically indistinguishable on presentation. Patients with aortic dissection may present with a wide variety of symptoms secondary to the pattern of dissection and end organ malperfusion. Other conditions may be seen in patients with acute symptoms, including ruptured and unstable thoracic aortic aneurysm, iatrogenic or infective pseudoaneurysms, aortic fistula, acute aortic thrombus/occlusive disease, and vasculitis. Imaging plays a pivotal role in the patient’s management and care. In the emergency room, chest X-ray is the initial imaging test offering a screening evaluation for alternative common differential diagnoses and a preliminary assessment of the mediastinal dimensions. State-of-the-art multidetector computed tomography angiography (CTA) provides a widely available, rapid, replicable, noninvasive diagnostic imaging with sensitivity approaching 100%. It is an impressive tool in decision-making process with a deep impact on treatment including endovascular or open surgical or conservative treatment. Radiologists must be familiar with the spectrum of these entities to help triage patients appropriately and efficiently. Understanding the imaging findings and proper measurement techniques allow the radiologist to suggest the most appropriate next management step.

Diagnostic value of 256 MDCT in diagnosis of coronary disease in atrial fibrillation patients

Objectives: To determine the diagnostic value of 256 MDCT in the diagnosis of coronary artery disease in patients with atrial fibrillation.Materials and methods: We prospectively enrolled 48 patients with atrial fibrillation who underwent 256 MDCT coronary CT angiography scan at Huu Nghi Hospital from 07/2020 to 07/2021 and evaluated diagnosis value of this technique using invasive coronary angiography as golden standard.Results: At patient-based analysis, sensitivity, specificity, positive predictive value and accuracy are 100%, 83.3% and 83.3%, respectively. At vessel-based analysis, sensitivity, specificity, positive predictive value, negative predictive value and accuracy are 98.4%, 81.7%, 80.3%, 98.5% and 88.9%, respectively. At segment-based analysis sensitivity, specificity, positive predictive value, negative predictive value and accuracy are 96.7%, 93.8%, 78.4%, 99.2 % and 94.4%, respectively. "Conclusion: 256 MDCT coronary angiography scan is a diagnostic method with high accuracy in diagnosing coronary artery disease in patients with atrial fibrillation.

Evaluation of Diagnostic Performance of MDCT Coronary Angiography in Comparison with Conventional Coronary Angiography

Abstract Background: Coronary artery disease is now becoming increasingly prevalent than before especially in younger age groups. We in the current study tried to evaluate the potential of 128 slice MDCT coronary angiography for the detection of stenotic coronary lesions by comparing the results of computed tomographic coronary angiography to a gold standard set by Conventional coronary angiography. Methods: A total of n=30 patients with clinically suspected Coronary artery disease. They were evaluated with 128 Slice CT Scanner (PHILIPS INGENUITY) and conventional coronary angiography. All patients were examined with a 128 slice MDCT scanner (Philips Ingenuity 128 slice Netherlands) using standard cardiac CT protocol. Gantry rotation time was 400 ms with a half sector acquisition protocol and multisector reconstruction permitting an effective temporal resolution between 50 and 200 ms depending on patient heart rate. Results: In the n=30 Patients included in the study with CCA, the n=450 coronary segments included in the study were found to contain a total number of n=138 stenoses among them non-significant stenoses. The accuracy of MDCT detection of coronary stenoses greater than 50% diameter of vessel lumen is about 94.78. When raising the threshold for stenosis from 50% to 70% of the vessel lumen, so that only hemodynamic relevant stenoses enter the evaluation, the sensitivity decreases from 88%. The MDCT detection in the patient group with heart rates below 60 beats per minute higher values for sensitivity 93% and specificity 97% were observed, compared to sensitivity 87% and specificity 93% of the patient group with heart rates above 60 beats per minute. Conclusion:The present study revealed that a high negative predictive value (98.08%)suggests that 128- Slice MDCT coronary angiography is a good screening modality for evaluation of patients with mild to intermediate-risk factors who might otherwise require invasive angiography.

Diagnostic Accuracy of MDCTA for Detection of Intracranial Aneurysm in Non Traumatic Subarachnoid Haemorrhage: A Cross-sectional Study

Introduction: Non Traumatic Subarachnoid Haemorrhage (NTSAH) constitutes a neurological emergency. Multi-Detector Computed Tomographic Angiography (MDCTA) provides significant advantages over Digital Subtraction Angiography (DSA) owing to its immediacy, non invasiveness, and comparable diagnostic accuracy. This warrants exploration of its utility as a fully integrated component of routine imaging and therapeutic algorithm for NTSAH, replacing DSA. Aim: To evaluate the potential of MDCTA of the Circle of Willis (COW) in the detection of causes of NTSAH and compare its diagnostic accuracy with DSA and/or intraoperative findings. Materials and Methods: This cross-sectional study enrolled 45 patients with suspected or confirmed intracranial vascular abnormality or SAH, and subjected to non contrast enhanced Computed Tomography (CT) and MDCTA of the COW. MDCTA findings like aneurysms, Arteriovenous Malformations (AVM), their morphological characteristics and anatomical COW variations were contrasted with DSA/operative findings in 24 patients and MDCTA’s accuracy was calculated. The data was analysed using statistical software R (Ross Ihaka and Robert Gentleman) v.4.0.2, employing Kappa coefficient. The p-value ≤0.05 indicated statistical significance. Results: Total of 45 subjects (mean age: 47.16±17.4 years, 17 females and 28 males) were included in the study. The mean aneurysmal size was 7.6±7.2 mm. Grade 3 or 4 (dense) SAH (48.88%) and aneurysms &lt;3 mm in size (48.89%) were most common. MDCTA showed sensitivity, specificity, and positive and negative predictive values of 89%, 79%, 84% and 85%, respectively. Kappa test revealed a substantial agreement between CTA and DSA (kappa coefficient=0.68). Conclusion: MDCTA is a rapid, minimally invasive, and reliable substitute to DSA in diagnosing and characterising associated aneurysms and AVM, in most cases of NTSAH, aiding in further management of such patients.

Multidetector Computed Tomography Angiographic Evaluation of Anatomical Variations in Popliteal Artery Branching: A Retrospective Study from Northern India

Introduction: The popliteal artery branching pattern has multiple variations which have implications in outcomes of various surgical procedures. Amongst cadaveric, Computed Tomography (CT) angiographic and Digital Subtraction Angiographic (DSA) studies, Multidetector Computed Tomography (MDCT) Angiography provides a comprehensive, quick and efficient evaluation of the popliteal arterial anatomy along with surrounding structures and related pathologies of the vascular and non-vascular structures. Aim: To evaluate the patterns of popliteal artery division on MDCT angiography of lower limb in patients presenting to a tertiary medical institute in Northern India. Materials and Methods: This retrospective descriptive study was conducted in Department of Radiology at Shri Guru Ram Rai Institute of Medical and Health Sciences, Dehradun, Uttarakhand, India (tertiary care medical institute of Northern India). Patients presenting for a period of one year from April 2021 to March 2022 were included in the study. The MDCT angiographic findings of 152 patients who were evaluated for various illness including peripheral vascular disease, popliteal arterial aneurysms and trauma were analysed. The branching pattern of popliteal artery was evaluated according to the classification system provided by Kim DU et al., Morphometric analysis of popliteal artery including diameter was also done. The imaging based data was collected and analysed by two radiologists. Chi-square test was used for statistical analysis. Results: The mean age of the patients was 54.18 years with males predominance of 110 (72.37%). Amongst the 304 limbs available for evaluation, the data from six limbs could not be assessed due to atherosclerotic blockage in four patients, extensive calcification in one patient and amputation in one patient. Hence, 298 limbs were evaluated on MDCT angiography for the pattern of branching of popliteal artery. Type IA was the most common pattern of division seen in 268 limbs (89.93%). Out of 298, 30 limbs showed variant anatomy, with unilateral variation in 18 patients and bilateral variation in six patients. Type III pattern (n=12, 4.03%) was more common than Type II pattern (n=11, 3.6%) in the study group. Conclusion: The knowledge of variations of popliteal arterial division and meticulous evaluation is essential to provide a successful roadmap for therapeutic measures.

Mesenteric Vascular Evaluation with Pre-operative Multidetector Computed Tomographic Angiography and Intraoperative Indocyanine Green Angiography to Reduce Anastomotic Leaks after Minimally Invasive Surgery for Colorectal Cancer

Background:The aim of this prospective study was to determine the effect of mesenteric vascular evaluation using pre-operative multidetector computed tomography angiography (MDCTA) and intraoperative indocyanine green (ICG) angiography on reducing the anastomotic leak rate of colorectal cancer patients undergoing minimally invasive resection.Methods:Twenty-seven consecutive patients with colorectal cancer were studied, 18 males and 9 females, average age 69.1 ± 3.9 years. All patients underwent pre-operative mesenteric vascular evaluation using MDCTA with three-dimensional (3D) reconstruction and intraoperative evaluation of perfusion using ICG angiography. Twelve patients underwent laparoscopic resection (Olympus Visera Elite II OTV-S200) and 15 patients underwent robotic resection (DaVinci Si). Colorectal resection lines and anastomoses were guided by intraoperative ICG perfusion. Postoperative anastomotic leaks were assessed.Results:Pre-operative MDCTA 3D reconstructions defined the left colic and sigmoid artery anatomy and guided operative planning. The intraoperative ICG angiography resulted in a change of the planned lines of resection in seven patients (26%). The rate of postoperative anastomotic leaks in this study was 0% (0/27), compared to a leak rate of 6.8% at our institution in the preceding two years.Conclusion:Pre-operative evaluation of mesenteric vascular anatomy using MDCTA with 3D reconstruction and intraoperative evaluation of perfusion using ICG angiography were found to be technically feasible and safe. An appropriately designed study should be undertaken to prove whether it was truly effective at reducing the postoperative anastomotic leak rate in colorectal cancer patients undergoing minimally invasive resection at our institution.

Partial anomalous pulmonary venous connection: state-of-the-art review with assessment using a multidetector computed tomography angiography.

Pulmonary venous anomalies occur as a result of failure in normal embryological development. These anomalies may present as a spectrum ranging from normal variation to partial anomalous pulmonary venous connection (PAPVC) and total anomalous pulmonary venous connection (TAPVC). Though not rare, PAPVC is an uncommon anomaly in which some of the pulmonary veins abnormally connect and drain into the vascular compartments other than the left atrium (LA); however, the others drain normally into the LA. The clinical presentation and severity of affected patients depend on the morphological heterogeneity of the disease. PAPVC associated with other complex conge-nital cardiac diseases present early and are more severe than isolated PAPVC-associated atrial septal defect only. This radiological review gives a detailed description of PAPVC in terms of morphological variability and associated anomalies along with a discussion of the role of multidetector dual-source computed tomography scan in the diagnostic assessment.

Magnetic Resonance Angiography and Multidetector CT Angiography in the Diagnosis of Takayasu's Arteritis: Assessment of Disease Extent and Correlation with Disease Activity.

Takayasu's Arteritis (TA) is a large vessel vasculitis with diverse clinical presentations and arterial vascular bed involvement.It is characterized by chronic, nonspecific inflammation of all layers of the vessel wall which results in stenosis, occlusion, dilatation, or aneurysm formation in the involved blood vessels. The study included 36 patients of TA. All patients fulfilled the modified Ishikawa's diagnostic criteria for TA. All patients were evaluated for clinical presentation, angiographic findings, and severity of the disease. The disease activity was assessed based on Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP) and also by CT Angiography (CTA)/Magnetic resonance angiography (MRA) imaging. The angiographic types were classified based on the International TA Conference in Tokyo 1994 angiographic classification. A total of 36 patients were included in the study, 86% were females and a mean age of 21.6 years. Hypertension (78%) was the most common clinical presentation. Type V was the most common angiographic type (42%) followed by type III (25%), type IV (14%), type IIb (11%), type I (5%) and type IIa (3%). Among the aortic arch branches the left subclavian artery (50%), right subclavian artery (38.8%), left vertebral artery (33.3%) and left common carotid artery (27.7%) were the most commonly involved arteries. Disease activity based on CT / MR imaging showed a significant statistical correlation with elevated ESR and positive CRP (p < 0.0001). Mediastinal lymphadenopathy was seen in 21 patients out of which 11 had active disease. However, no significant correlation was found between mediastinal lymphadenopathy and disease activity. TA presents with varied symptomatology and differing vascular involvement. CT/MR angiography is effective in diagnosis and accurately predicted the active stage of the disease.

Role of computed tomography angiography in the evaluation of haemoptysis in children: Decoding the abnormal vessels.

Haemoptysis in children is potentially life-threatening. In most cases, the bleeding arises from the systemic circulation, and in 5-10 per cent of cases, it arises from the pulmonary circulation. The role of computed tomography angiography (CTA) in this setting is important. This study was undertaken (i) to study the role of single-phase split-bolus dual energy contrast-enhanced multidetector row CTA (DECTA) in the evaluation of haemoptysis in children; (ii) to analyze the patterns of abnormal vascular supply in the various aetiologies encountered. A retrospective study of 86 patients who underwent split bolus DECTA for the evaluation of haemoptysis was performed. Final diagnoses were categorized as normal computed tomography, active tuberculosis (TB), post-infectious sequelae, non-TB active infection, cystic fibrosis (CF), non-CF bronchiectasis, congenital heart disease (CHD), interstitial lung disease, vasculitis, pulmonary thromboembolism and idiopathic pulmonary haemosiderosis. Abnormal bronchial arteries (BAs) and non-bronchial systemic collateral arteries (NBSCs) were assessed for number and site and their correlation with underlying aetiologies. A total of 86 patients (45 males, age from 0.3 to 18 yr, mean 13.88 yr) were included in the study; among these only two patients were less than five years of age. The most common cause of haemoptysis was active infection (n=30), followed by bronchiectasis (n=18), post-infectious sequelae (n=17) and CHD (n=7). One hundred and sixty five abnormal arteries were identified (108 BA and 57 NBSC), and were more marked in bronchiectasis group. Active infections and bronchiectasis are the most common causes of haemoptysis in children. While post-infectious sequelae are less common, in patients with haemoptysis, the presence of any abnormal arteries correlates with a more frequent diagnosis of bronchiectasis. NBSCs are more common in post-infectious sequelae and CHD.