This paper evaluates the feasibility of using shredded tires for removal of organic compounds from landfill leachate. From the batch sorption isotherm experiments, tire chips were found to have 1.4% to 5.6% of the sorption capacity of granular activated carbon on a volume basis. The sorption equilibrium occurred within 2 days for 0.6‐, 1.3‐, and 2.5‐cm size tire chips. The capacity of tire chips to adsorb organic compounds in a multisolute system was almost equal to that in single‐solute systems. Only 3.4% to 7.9% of the organic compounds sorbed in tire chips were desorbed. A design method was proposed to estimate the thickness of a tire layer required for a target organic compound removal from the landfill leachate based on a structure‐activity relationship obtained from laboratory tests.