The aim of this research is to study the dynamic facility layout and job-shop scheduling problems, simultaneously. In fact, this paper intends to measure the synergy between these two problems. In this paper, a multi-objective mixed integer nonlinear programming model has been proposed where areas of departments are unequal. Using a new approach, this paper calculates the farness rating scores of departments beside their closeness rating scores. Another feature of this paper is the consideration of input and output points for each department, which is crucial for the establishment of practical facility layouts in the real world. In the scheduling problem, transportation delay between departments and machines' setup time are considered that affect the dynamic facility layout problem. This integrated problem is solved using a hybrid two-phase algorithm. In the first phase, this hybrid algorithm incorporates the non-dominated sorting genetic algorithm. The second phase also applies two local search algorithms. To increase the efficacy of the first phase, we have tuned the parameters of this phase using the Taguchi experimental design method. Then, we have randomly generated 20 instances of different sizes. The numerical results show that the second phase of the hybrid algorithm improves its first phase significantly. The results also demonstrate that the simultaneous optimization of those two problems decreases the mean flow time of jobs by about 10% as compared to their separate optimization.
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