Mucous Extravasation Cyst Research Articles

Immunolocalization of aromatase in human minor salivary glands of the lower lip with primary Sjögren's syndrome.

The enzyme aromatase is involved in the conversion of androgens to estrogens and in the modulation of various androgenic and estrogenic actions. Abnormalities of estrogen metabolism have been postulated to play roles in the development and/or pathophysiology of Sjögren's syndrome. In the present study, aromatase was immunolocalized in 75 cases of inflammatory disorders of human minor salivary glands of the lower lip. These included cases of primary Sjögren's syndrome (19 cases), of chronic sialadenitis (34 cases) and of mucous extravasation cysts (22 cases), in order to clarify the possible involvement of in situ estrogen production in primary Sjögren's syndrome. Aromatase immunoreactivity was detected in myoepithelial cells of acini and in interstitial cells adjacent to acini and ducts in 13/19 (68%) cases of primary Sjögren's syndrome. In contrast, aromatase expression was detected in only six of 34 (18%) cases of chronic sialadenitis and in seven of 22 (32%) cases of mucous extravasation cyst. These results suggest that increased aromatase expression in minor salivary glands with primary Sjögren's syndrome in premenopausal women may be involved in the biological features of primary Sjögren's syndrome through the production of estrogens in situ and possibly through the aggravation of the inflammatory reaction.

Clinicostatistical study of lower lip mucoceles

We reviewed 70 patients with lower lip mucoceles for patient characteristics, clinical features, and histopathologic findings. These cases represented approximately 75% of oral mucoceles seen in the Department of Otolaryngology, Takeda General Hospital, between February 1985 and July 1988. Patients were divided almost equally between males and females, with ages ranging from 2 to 63 years, with the highest incidence of lesions occurring in the second decade. Duration of the lesions varied greatly from a few days to 3 years, with no correlation to size. The most commonly affected site was opposite the upper lateral incisor, with the incidence divided almost equally between right and left side. Of 70 biopsies, 68 were mucous extravasation cysts and 2 were mucous retention cysts. Surgical excision was the treatment of choice, with recurrence of the lesion in only 2 cases.

Salivary extravasation cyst of the tongue

Although mucoceles are very common, it is rare to find them in babies. A case is presented in which a large mucous extravasation cyst involving the ventral surface of tongue was treated in a 10-week-old baby.

Cervical mucocele (plunging ranula): An unusual case of mucous extravasation cyst

An unusual case of a mucous extravasation cyst that manifest itself solely as a cervical swelling is reported. As a result of this unusual symptom, diagnosis and appropriate treatment were delayed, and the condition finally resolved after the ipsilateral sublingual salivary gland was excised and the cervical fluid was aspirated. Cervical mucoceles have also been reported in dogs, and the veterinary literature pertaining to this is briefly reviewed.

The association between perioral injury and mucoceles

Because the origin of perioral mucous extravasation cysts (mucoceles) has been associated with injury to the glandular apparatus in the lips and cheeks it was decided to compare two groups of subjects, the one group having a known history of violent and antisocial behaviour and the other not. 474 institutionalized reform school boys and 532 randomly selected boys from state schools were examined. 48.9% of the reform boys and 2.8% of the state school pupils ( p < 0.0001) had oral scars. Mucoceles were observed in 8.2% of reform boys and 0.8% of state school boys ( p < 0.0001), the former being the highest prevalence of mucoceles reported as yet in man. 60% of the cases with mucoceles could relate the advent of the mucocele to an injury, and a significant relationship exists between the occurrence of mucoceles and the presence of oral scars ( p < 0.001). The study strongly suggests a direct relationship between oral injury and the origin of mucoceles.

An unusual complication of circumferential wiring

Summary A case is described of a patient who sustained a fracture of his mandible and developed a mucous extravasation cyst of a major salivary gland as a complication of treatment utilising circumferential wire

MUCOCELES OF THE ORAL CAVITY.

T here have been few large series of mucoceles reported in the literature. Although Thoma and GoldmanlG state that mucocelcs are cysts lined with ductal epithelium and that they are caused by obstruction of the duct of a mucous gland, Bhaskar and associates2 failed to demonstrate an epithelial lining in any of their nineteen cases of mucoceles. Mpiller12 examined histologically nineteen out of a series of forty-four clinical cases and found an epithelial lining in only one. In a series of ninety-seven cases, Standish and ShafeF found epithelial linings in four cases. Chaudhry and colleagues3 reported sixty-six cases, in none of which was there an epithelial lining. The present series of eighty cases is reported for comparison with previous studies of the age incidence, sex incidence, sites of occurrence, and histologic features. The purpose of this article is to show that there are two types of mucocelcs-one in which mucus has extravasated into the tissues and may or may not be enclosed by granulation tissue (mucous extravasation cyst) and one which is lined with epithelium (mucous retention cyst). The mucous extravasation cyst is the more common type. Included in the eighty cases of mucocele are seven cases in which lesions were diagnosed clinically as ranulas.