Irritable Bowel Research Articles

A Novel Tailored Oligoantigenic Dietary Approach for Irritable Bowel Syndrome (IBS)

A Novel Tailored Oligoantigenic Dietary Approach for Irritable Bowel Syndrome (IBS)

S743 Sex-specific Response Patterns to Tricyclic Antidepressants in Patients With Diarrhea-Predominant Irritable Bowel Syndrome: A Propensity-Matched, Retrospective Cohort Study

S743 Sex-specific Response Patterns to Tricyclic Antidepressants in Patients With Diarrhea-Predominant Irritable Bowel Syndrome: A Propensity-Matched, Retrospective Cohort Study

S1076 The Association Between Co-Morbid Irritable Bowel Syndrome and Outcomes in Hospitalized Patients With Inflammatory Bowel Disease

S1076 The Association Between Co-Morbid Irritable Bowel Syndrome and Outcomes in Hospitalized Patients With Inflammatory Bowel Disease

S745 Efficacy and Safety of Plecanatide in Treatment of Irritable Bowel Syndrome With Constipation and Chronic Idiopathic Constipation

S745 Efficacy and Safety of Plecanatide in Treatment of Irritable Bowel Syndrome With Constipation and Chronic Idiopathic Constipation

Postbiotics: A new member in the biotics family.

Postbiotics were defined in 2021 by the International Scientific Association for Probiotics and Prebiotics (ISAPP) as a "preparation of inanimate microorganisms and/or their cellular components that confers a health benefit to the host." The field of postbiotics is a new area within the biotics family; numerous products have already been developed for clinical applications, such as immune stimulation, the management of diarrhea in children and adults, the management of irritable bowel syndrome, and 3 infant formulas. In particular, infant formulas with postbiotics obtained from milk fermented with Bifidobacteriumbreve C50 and Streptococcusthermophilus O65 -and their metabolites-, including the oligosaccharide 3'-GL, have demonstrated to be safe and to contribute to the development of the gut microbiota and the gutassociated immune system. These modifications help to prevent and manage functional gastrointestinal disorders in infants.

S736 Probing Probiotics: A Systematic Review and Meta-analysis on the Efficacy of Various Probiotic Regimens in the Management of Irritable Bowel Syndrome

S736 Probing Probiotics: A Systematic Review and Meta-analysis on the Efficacy of Various Probiotic Regimens in the Management of Irritable Bowel Syndrome

S2251 The Impact of Low-FODMAP Diet in Managing Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis

S2251 The Impact of Low-FODMAP Diet in Managing Irritable Bowel Syndrome: An Updated Systematic Review and Meta-Analysis

Evaluation of nutrition literacy, quality of life, and gastrointestinal symptoms in individuals experiencing irritable bowel syndrome symptoms

Evaluation of nutrition literacy, quality of life, and gastrointestinal symptoms in individuals experiencing irritable bowel syndrome symptoms

Exploring online health resources and self-care among irritable bowel syndrome patients: analyzing internet use and AI chatbot interactions

Exploring online health resources and self-care among irritable bowel syndrome patients: analyzing internet use and AI chatbot interactions

S747 From Discomfort to Relief: The Influence of YouTube on Irritable Bowel Syndrome Education

S747 From Discomfort to Relief: The Influence of YouTube on Irritable Bowel Syndrome Education

S793 Hormone Replacement Therapy is Associated With Increased Risk of Developing Irritable Bowel Syndrome in Post-Menopausal Women

S793 Hormone Replacement Therapy is Associated With Increased Risk of Developing Irritable Bowel Syndrome in Post-Menopausal Women

S826 The Association of Irritable Bowel Syndrome With Improved Clinical Outcomes in Upper Gastrointestinal Bleeding

S826 The Association of Irritable Bowel Syndrome With Improved Clinical Outcomes in Upper Gastrointestinal Bleeding

S759 Irritable Bowel Syndrome With Constipation Poses a Substantial Burden to Patient Overall Health Status and Quality of Life: Results From the IBS in America 2024 Real-World Survey

S759 Irritable Bowel Syndrome With Constipation Poses a Substantial Burden to Patient Overall Health Status and Quality of Life: Results From the IBS in America 2024 Real-World Survey

Assessment of reliability and information quality of youtube videos about dietary recommendations for irritable bowel syndrome

Assessment of reliability and information quality of youtube videos about dietary recommendations for irritable bowel syndrome

S823 Kiwifruit and Kiwifruit Extracts for Treatment of Constipation in Healthy Plus Functional Constipation Including Irritable Bowel Syndrome Type Constipation Patient: A Meta-Analysis

S823 Kiwifruit and Kiwifruit Extracts for Treatment of Constipation in Healthy Plus Functional Constipation Including Irritable Bowel Syndrome Type Constipation Patient: A Meta-Analysis

S938 Evaluating the Impact of Irritable Bowel Syndrome on Clinical Outcomes in Lower Gastrointestinal Bleeding

S938 Evaluating the Impact of Irritable Bowel Syndrome on Clinical Outcomes in Lower Gastrointestinal Bleeding

Bridging the Gap: A Comprehensive Study on Traditional Chinese Medicine Strategies for Managing Adult Irritable Bowel Syndrome.

Recent studies have witnessed the incorporation of herbal medicine into the management of Disorders of Gut-Brain Interactions (DGBIs), reflecting a paradigm shift toward holistic healing modalities. However, there still exists a substantial gap in comprehending the utilization of Traditional Chinese Medicine (TCM) for Irritable Bowel Syndrome (IBS), particularly beyond the confines of China. This study endeavors to bridge this knowledge gap by meticulously identifying existing guidelines, critically reviewing TCM practices, and crafting contemporary treatment recommendations. We systematically searched several databases to retrieve related evidence in June 2023. Firstly, we employed the AGREE II tool to evaluate the recommended for use of TCM in the treatment of IBS, establishing a structured treatment selection hierarchy for different TCM patterns of IBS patients. Subsequently, we conducted an expert questionnaire to gain insights into the common treatment methods and medication choices practiced by clinical TCM doctors. Based on CM theory and experts' opinions, IBS with predominant Diarrheal (IBS-D) is divided into five Chinese medicine syndrome patterns, and IBS with predominant Constipation (IBS-C) is classified to four. A total of 22[Formula: see text]CM prescriptions were recommended for the management of IBS, 13 for IBS-D and 9 for IBS-C. The findings provide IBS patients with enhanced treatment choices while offering clinical physicians more specific treatment regimens. This research is the first to conduct a comprehensive study that combines guidelines with real clinical practices in the realm of TCM IBS treatment. This serves as a foundation for providing more personalized treatment options and improving the quality of life for patients.

An Exploratory Study on Integrative Management of Irritable Bowel Syndrome with Constipation (IBS-C)

Irritable Bowel Syndrome (IBS) was complicated disorder that results in pain and change in bowel habits. The major contributing factors to the onset and detoriation include stress and gastrointestinal problem. The women between 20 to 40 years were most commonly involved. The prevalence varies among countries that was affected by diet and diagnostic criteria. Objective: Compairing the efficacy of Mebeverine, Polyethylene Glycol with the combination therapy of Mebeverine and Polyethylene Glycol in Irritable Bowel Syndrome associated with Constipation. Methods: The comparative analytical study was conducted at the National Medical Centre, Karachi, and approved by the Ethical Review Committee of Bahria University Health Science Campus. Participants aged 15-50 with IBS were selected to reflect the target population. Observational data were collected based on the treatments they naturally received: Mebeverine, Polyethylene glycol, or a combination. Pain and constipation status were recorded at baseline (day 0) and after 24 days, analyzing the effectiveness of the treatments as they were administered in routine care settings. Results: The demographic data mentioned comparable age, weight, height, and gender distribution across the three groups. Constipation and pain status before and after varied considerably across the investigation time. There was substantial improvements by day 24 from the baseline in the combination therapy. Conclusions: The combination of Mebeverine and Polyethylene glycol reveals in managing IBS, with prominent improvements in constipation severity over the research duration. This highlights the importance of multimodal treatment methods in addressing the varied symptoms of IBS and enhancing the quality of life.

The role of pharmaceutical care in the use of rifaximin for the treatment of diarrhea

the management of diarrhea represents a prevalent issue within the realm of healthcare. Rifaximin is recommended to treat traveler's diarrhea and irritable bowel syndrome. At the same time, it is important to rationally use an antimicrobial drug to prevent the development of antimicrobial resistance. Aim: to evaluate the role of pharmaceutical care in using rifaximin to treat diarrhea, based on a questionnaire. A questionnaire survey was done among 55 pharmacy professionals and 42 pharmacy visitors regarding the dispensing and use of rifaximin for diarrhea treatment. The survey of pharmacy visitors revealed that rifaximin was used for the treatment of small intestinal bacterial overgrowth syndrome (32 cases), traveler's diarrhea (7 cases), and irritable bowel syndrome with diarrhea (3 cases). Patients did not undergo stool culture before rifaximin prescription, which could have prevented antimicrobial resistance and ruled out other causes of diarrhea. It was found that 14% of respondents reported improvement the next day, while 83.3% reported improvement within three days. Pharmacists can educate visitors about the importance of completing the treatment course. Five percent of respondents reported nausea as an adverse reaction. Pharmacists dispensed rifaximin for the treatment of diarrhea in adults almost three times more often than in children. The tablet form of the drug was used in 94.5% of cases, while the oral suspension was used in 5.5% of cases. The majority of pharmacy visitors (89.0%) received rifaximin with a doctor's prescription, and 10.9% without a prescription, which emphasizes the importance of pharmaceutical care to prevent irrational use of the drug. The results of the study show that 92.7% of pharmacists provide recommendations on the safety of rifaximin use, and 78.2% recommend abstaining from alcohol during treatment. Only 21.8% of pharmacists warn about the possible staining of urine, which can cause concern for patients. The majority of pharmacists (89.1%) systematically ask women about possible pregnancy, which indicates their awareness of safe pharmacotherapy. Pharmacists also clarify the simultaneous use of rifaximin with other drugs: 32.7% ask about taking oral contraceptives, 7.3% – antiarrhythmic drugs, and 3.6% – warfarin. mailto:https://meshb.nlm.nih.gov/record/ui?ui=D002648Pharmacists can enhance the effectiveness of rifaximin treatment by preventing its uncontrolled use, emphasizing the importance of completing the treatment course and informing about possible adverse reactions. When providing pharmaceutical care to visitors taking rifaximin, pharmacists should educate them about potential changes in urine color. Additionally, pharmaceutical workers advise women taking oral contraceptives to use additional contraceptive methods while taking rifaximin.

Air pollution, dysbiosis and diseases: pneumonia, asthma, COPD, lung cancer and irritable bowel syndrome.

With substantial effects on human health, air pollution has become a major global concern. Air pollution has been linked to numerous gastrointestinal and respiratory diseases with increasing mortalities. The gut and respiratory dysbiosis brought about by air pollution has recently received much attention. This review attempts to provide an overview of the types of air pollutants, their sources, their impact on the respiratory and gut dysbiotic patterns and their correlation with five major diseases including pneumonia, asthma, COPD, lung cancer and irritable bowel syndrome. Deeper insights into the links between pollutants, dysbiosis and disease may pave the way for novel diagnostic biomarkers for prognosis and early detection of these diseases, as well as ways to ease the disease burden.