Mucosa In Health Research Articles

Abstracts of the First International Symposium on Biochemistry of the Gut Mucosa in Health and Disease: From basic science to clinical perspectives

Abstracts of the First International Symposium on Biochemistry of the Gut Mucosa in Health and Disease: From basic science to clinical perspectives

Book Review

The book reviews are in this article: Laboratory Procedures for Inlays, Crowns and Bridges By Derek Stananought, edited by J.M. Mumford. Oral Mucosa in Health and Disease Edited by A. E. Dolby. Designing Complete Dentures By D.M. Watt and A.R.MacGregor. Dental Materials Review Edited by Robert G. Craig.

Oral Mucosa in Health and Disease

Oral Mucosa in Health and Disease

Oral Mucosa in Health and Disease

Medical Journal of AustraliaVolume 2, Issue 23 p. 881-881 Book Reviews Oral Mucosa in Health and Disease Mark Jolly, Mark JollySearch for more papers by this author Mark Jolly, Mark JollySearch for more papers by this author First published: 01 December 1976 https://doi.org/10.5694/j.1326-5377.1976.tb115452.xAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat No abstract is available for this article. Volume2, Issue23December 1976Pages 881-881 RelatedInformation

Book Reviews

Book reviews of this article:Human Pulp Response to Operative Denial Procedures, by Harold R. Stanley. ShorterOral Mucosa in Health and Disease, edited by A. F. Dolby.“Advanced Denial Histology”, J. W. Osborn and A. R. Ten Cate, 3rd ed.“1976 Yearbook of Dettlistry”, Sidney B. Finn, M. L. Hale, S. P. Hazen, R. E. Moyers, H. B. G. Robinson and S. I. Silverman.“Craniofacial luuhryology”, 2nd ed., by G. H. Sperber

Oral Mucosa in Health and Disease

Oral Mucosa in Health and Disease

Dissecting microscopy of the rectal mucosa in health and disease.

The dissecting-microscopic appearance of the human rectal mucosa was studied in 147 biopsy specimens. The normal mucosa is divided into mucosal units by a “honeycomb” pattern of the rectal microvasculature, the center of each unit containing a refractile “pit” which may represent the mouth of the rectal crypt. The changes occurring in ulcerative colitis were graded according to severity of disturbance of the vascular channels, ranging from dilatation, neoformation and tortuosity of the individual vessels to complete disorganization of the “honeycomb” pattern. The vascular and “pit” changes in ulcerative colitis and other diseases of the rectum are described. The pathogenesis of the dissecting-microscopic changes is discussed in relation to the normal vascular pattern of the human colonic mucosa.

Middle ear mucosa in health and disease.

Study of the mucous membrane of the middle ear in a variety of normal and pathological conditions showed that the simple squamous and simple cuboidal epithelium predominates in the normal as well as the pathological middle ear. However, metaplasia to a respiratory or even stratified squamous epithelium may occur in long-term inflammatory diseases. It is felt that the changes found in secretory otitis media are due to an inflammatory disease process. The findings of metaplasia of the epithelium, increased gland formation, and the presence of inflammatory cells in almost half the cases of secretory otitis suggests that the disease is, most likely, an inflammatory one, and not entirely due to hypoventilation of the middle ear.

DIAGNOSIS AND TREATMENT: PERORAL INTESTINAL BIOPSY

Understanding of the function and appearance of the intestinal mucosa in health and disease has rapidly increased with the development of instruments for taking small intestinal biopsies by the oral route. Early studies in the adult, little more than a decade ago, employed a variety of ingenious devices developed by Royer and co-workers,1 Shiner,2 Crosby and Kugler,3 Rubin and co-workers,4 and others. Most of them "sucked up" a bit of the mucosal surface into a small orifice of a capsule, appropriately placed in the intestine, detached the section by a sharp knife blade, and withdrew it in the capsule. Early workers were understandably reluctant to study pediatric patients, but in recent years a number of pediatricians have used these devices effectively. METHODS Although the mucosal biopsy obtained from any segment of the small bowel generally weighs only 5 to 15 mg, it may be profitably examined by numerous techniques: the gross morphological, the histological, histochemical, biochemical, and electron microscopic. For routine study, considerable information can be gained by observing the specimen under a dissecting microscope and by histologic examination of carefully oriented and cut sections. Rubin has pointed out the difficulties and errors in interpretation of inadequately prepared sections. The plane of sectioning should be parallel to the villi and perpendicular to the luminal suface. Microtechniques for assay of disaccharidasese can be applied with a high degree of reliability. The activity of lactase, sucrase, maltase, and palatinase can be expressed as activity per unit of wet weight of tissue or per unit of tissue protein content.

Three-dimensional structure of the human small intestinal mucosa in health and disease.

Three-dimensional structure of the human small intestinal mucosa in health and disease.