Segmentation Of Magnetic Resonance Images Research Articles

Deep Learning Approaches in Medical Image Segmentation: Implications for Brain Tumor Detection and Analysis

The procedure of image segmentation involves splitting images into distinct components to discern similarities or differences between regions. This facilitates the quantitative and/or qualitative analysis of lesions, thereby enhancing the reliability and accuracy of medical diagnoses. Traditionally, medical image segmentation was performed manually, slice by slice, requiring a high level of expertise to accurately define boundaries for individual areas. This manual process is time-consuming and error-prone. Currently, several deep learning methods have achieved significant advancements in image segmentation, surpassing the accuracy of traditional approaches. This study reviewed the effectiveness of deep learning models in accurately segmenting images of brain tumor patients. A search of the PubMed and Google Scholar databases, as well as the Asian Journal archives, was conducted to retrieve recent literature using the keywords: deep learning, Magnetic Resonance Imaging, image segmentation, and medical image processing. References from relevant literature were also reviewed to obtain additional sources. A critical and direct assessment of deep learning technologies on tumor MRI images was subsequently performed using these sources. The Dice scores served as metrics for evaluating the performance of the deep learning models. Based on the Dice scores, it can be inferred that deep learning models such as 3D FCNs, ResNet models, AGSE-VNet models, and encoder-decoder CNN architectures exhibit high segmentation accuracy in brain tumor images. The promising results demonstrated by deep learning-based segmentation approaches underscore their potential to enhance diagnostic capabilities in brain tumor detection and analysis.

The structural effects of transcranial magnetic stimulation on hippocampal subfields in Alzheimer's disease

Aim: This study investigates the structural effects of repetitive transcranial magnetic stimulation (rTMS) on hippocampal subfields and cortical shape metrics in Alzheimer’s disease (AD) patients. Using high-resolution MRI segmentation and analysis via Hippunfold, we aim to elucidate TMS-induced structural changes and assess its potential neuroprotective role. Methods: This retrospective study included 17 AD patients and 18 healthy controls (HC). AD patients underwent 20 Hz rTMS targeting the left lateral parietal cortex over 10 sessions across two weeks. Magnetic resonance imaging (MRI) data were acquired before and after rTMS and analyzed with Hippunfold to segment hippocampal subfields and extract cortical thickness and shape metrics. Statistical analyses were performed to compare subfield volumes and cortical metrics between groups and across time points. Results: Hippocampal volumetric analysis revealed significant atrophy in subfields such as Cornu Ammonis 1, (CA1), CA2, CA4, dentate gyrus (DG), subiculum, and stratum radiatum-lacunosum-moleculare (SRLM) in AD patients compared to HC. Although no significant volumetric recovery was observed post-TMS, a further decline was noted in the right CA3 subfield (p=0.005), highlighting progressive atrophy. Cortical shape analyses showed significant reductions in hippocampal thickness (p

Transformers for Neuroimage Segmentation: Scoping Review.

Neuroimaging segmentation is increasingly important for diagnosing and planning treatments for neurological diseases. Manual segmentation is time-consuming, apart from being prone to human error and variability. Transformers are a promising deep learning approach for automated medical image segmentation. This scoping review will synthesize current literature and assess the use of various transformer models for neuroimaging segmentation. A systematic search in major databases, including Scopus, IEEE Xplore, PubMed, and ACM Digital Library, was carried out for studies applying transformers to neuroimaging segmentation problems from 2019 through 2023. The inclusion criteria allow only for peer-reviewed journal papers and conference papers focused on transformer-based segmentation of human brain imaging data. Excluded are the studies dealing with nonneuroimaging data or raw brain signals and electroencephalogram data. Data extraction was performed to identify key study details, including image modalities, datasets, neurological conditions, transformer models, and evaluation metrics. Results were synthesized using a narrative approach. Of the 1246 publications identified, 67 (5.38%) met the inclusion criteria. Half of all included studies were published in 2022, and more than two-thirds used transformers for segmenting brain tumors. The most common imaging modality was magnetic resonance imaging (n=59, 88.06%), while the most frequently used dataset was brain tumor segmentation dataset (n=39, 58.21%). 3D transformer models (n=42, 62.69%) were more prevalent than their 2D counterparts. The most developed were those of hybrid convolutional neural network-transformer architectures (n=57, 85.07%), where the vision transformer is the most frequently used type of transformer (n=37, 55.22%). The most frequent evaluation metric was the Dice score (n=63, 94.03%). Studies generally reported increased segmentation accuracy and the ability to model both local and global features in brain images. This review represents the recent increase in the adoption of transformers for neuroimaging segmentation, particularly for brain tumor detection. Currently, hybrid convolutional neural network-transformer architectures achieve state-of-the-art performances on benchmark datasets over standalone models. Nevertheless, their applicability remains highly limited by high computational costs and potential overfitting on small datasets. The heavy reliance of the field on the brain tumor segmentation dataset hints at the use of a more diverse set of datasets to validate the performances of models on a variety of neurological diseases. Further research is needed to define the optimal transformer architectures and training methods for clinical applications. Continuing development may make transformers the state-of-the-art for fast, accurate, and reliable brain magnetic resonance imaging segmentation, which could lead to improved clinical tools for diagnosing and evaluating neurological disorders.

CDCG-UNet: Chaotic Optimization Assisted Brain Tumor Segmentation Based on Dilated Channel Gate Attention U-Net Model.

Brain tumours are one of the most deadly and noticeable types of cancer, affecting both children and adults. One of the major drawbacks in brain tumour identification is the late diagnosis and high cost of brain tumour-detecting devices. Most existing approaches use ML algorithms to address problems, but they have drawbacks such as low accuracy, high loss, and high computing cost. To address these challenges, a novel U-Net model for tumour segmentation in magnetic resonance images(MRI) is proposed. Initially, images are claimed from the dataset and pre-processed with the Probabilistic Hybrid Wiener filter (PHWF) to remove unwanted noise and improve image quality. To reduce model complexity, the pre-processed images are submitted to a feature extraction procedure known as 3D Convolutional Vision Transformer (3D-VT). To perform the segmentation approach usingchaotic optimization assisted Dilated Channel Gate attention U-Net (CDCG-UNet)model to segment brain tumour regions effectively. The proposed approach segments tumour portions as whole tumour (WT), tumour Core (TC), and Enhancing Tumour (ET) positions. The optimization loss function can be performed using the Chaotic Harris Shrinking Spiral optimization algorithm (CHSOA). The proposed CDCG-UNet model is evaluated with three datasets: BRATS 2021, BRATS 2020, and BRATS 2023. For the BRATS 2021 dataset, the proposed CDCG-UNet model obtained a dice score of 0.972 for ET, 0.987 for CT, and 0.98 for WT. For the BRATS 2020 dataset, the proposed CDCG-UNet model produced a dice score of 98.87% for ET, 98.67% for CT, and 99.1% for WT. The CDCG-UNet model is further evaluated using the BRATS 2023 dataset, which yields 98.42% for ET, 98.08% for CT, and 99.3% for WT.

Application of MRI image segmentation algorithm for brain tumors based on improved YOLO.

To assist in the rapid clinical identification of brain tumor types while achieving segmentation detection, this study investigates the feasibility of applying the deep learning YOLOv5s algorithm model to the segmentation of brain tumor magnetic resonance images and optimizes and upgrades it on this basis. The research institute utilized two public datasets of meningioma and glioma magnetic resonance imaging from Kaggle. Dataset 1 contains a total of 3,223 images, and Dataset 2 contains 216 images. From Dataset 1, we randomly selected 3,000 images and used the Labelimg tool to annotate the cancerous regions within the images. These images were then divided into training and validation sets in a 7:3 ratio. The remaining 223 images, along with Dataset 2, were ultimately used as the internal test set and external test set, respectively, to evaluate the model's segmentation effect. A series of optimizations were made to the original YOLOv5 algorithm, introducing the Atrous Spatial Pyramid Pooling (ASPP), Convolutional Block Attention Module (CBAM), Coordinate Attention (CA) for structural improvement, resulting in several optimized versions, namely YOLOv5s-ASPP, YOLOv5s-CBAM, YOLOv5s-CA, YOLOv5s-ASPP-CBAM, and YOLOv5s-ASPP-CA. The training and validation sets were input into the original YOLOv5s model, five optimized models, and the YOLOv8s model for 100 rounds of iterative training. The best weight file of the model with the best evaluation index in the six trained models was used for the final test of the test set. After iterative training, the seven models can segment and recognize brain tumor magnetic resonance images. Their precision rates on the validation set are 92.5, 93.5, 91.2, 91.8, 89.6, 90.8, and 93.1%, respectively. The corresponding recall rates are 84, 85.3, 85.4, 84.7, 87.3, 85.4, and 91.9%. The best weight file of the model with the best evaluation index among the six trained models was tested on the test set, and the improved model significantly enhanced the image segmentation ability compared to the original model. Compared with the original YOLOv5s model, among the five improved models, the improved YOLOv5s-ASPP model significantly enhanced the segmentation ability of brain tumor magnetic resonance images, which is helpful in assisting clinical diagnosis and treatment planning.

EF-VPT-Net: Enhanced Feature-Based Vision Patch Transformer Network for Accurate Brain Tumor Segmentation in Magnetic Resonance Imaging

EF-VPT-Net: Enhanced Feature-Based Vision Patch Transformer Network for Accurate Brain Tumor Segmentation in Magnetic Resonance Imaging

Intelligent Medical System for Diagnosis of Intervertebral Disc Deformation

The article examines the application of semi-supervised learning and computer vision methods for segmentation of spine MR images and diagnosis of deformation of intervertebral discs. Existing neural network architectures for spine MR image segmentation and semi-supervised learning methods used in medical image segmentation are reviewed. A system for diagnosis deformation of intervertebral discs is proposed, which consists of two modules: a segmentation module and a diagnostic module. The implementation of the proposed system using two convolutional neural networks is presented: U-Net for segmentation of spine MR images and ResNet for classification of the degree of deformation of each intervertebral disc based on the Pfirrmann classification of degenerative changes. The software implementation of the medical diagnosis system was developed in the Python programming language using the PyTorch library. Neural networks were trained on an open dataset of spine MR images using a variant of the Mean Teacher semi-supervised learning method. As a result of the verification, it was found that the system is capable of performing segmentation with high accuracy. It was found that the exact prediction of the grade of degenerative changes according to Pfirrmann remains a difficult task, but the introduction of another classification made it possible to increase the accuracy of diagnosis of deformation of intervertebral discs. The proposed medical system involves the addition of new diagnostic modules, which makes it possible to use it for the comprehensive analysis of various spine diseases

Assessment of Regional Brain Volume Measurements with Different Brain Extraction and Bias Field Correction Methods in Neonatal MRI

Proper selection and application of preprocessing steps are crucial for obtaining accurate segmentation in brain Magnetic Resonance Imaging (MRI). The aim of this study is to evaluate the impact brain extraction (BE) and bias field correction (BFC) methods have on regional brain volume (RBV) measurements of preterm neonates’ T2w MRI at term-equivalent age (TEA). Five BE methods (Manual, BET2, SWS, HD-BET, SynthStrip) were applied together with two BFC methods (SPM-BFC and N4ITK), before segmenting the neonatal brain into eight tissue classes (cortical grey matter, white matter, cerebral spinal fluid, deep nuclear grey matter, hippocampus, amygdala, cerebellum, and brainstem) using an automated segmentation software (MANTiS). Quantitative assessments were conducted, including the coefficient of variation (CV), coefficient of joint variation (CJV), Dice coefficient (DC), and RBV. HD-BET, together with N4ITK, showed the highest performance (mean ± standard deviation) regarding CV of 0.047 ± 0.005 (white matter) and 0.070 ± 0.005 (grey matter), CJV of 0.662 ± 0.095, DC of 0.942 ± 0.063, and RBV without significant differences (except in the brainstem) from the manual segmentation. Therefore, such combination of methods is recommended for improved skull-stripping accuracy, intensity homogeneity, and reproducibility of RBV of T2w MRI at TEA.

Automatic segmentation of pericardial adipose tissue from cardiac MR images via semi-supervised method with difference-guided consistency.

Accurate and automatic segmentation of pericardial adipose tissue (PEAT) in cardiac magnetic resonance (MR) images is essential for the diagnosis and treatment of cardiovascular diseases. Precise segmentation is challenging due to high costs and the need for specialized knowledge, as a large amount of accurately annotated data is required, demanding significant time and medicalresources. In order to reduce the burden of data annotation while maintaining the high accuracy of segmentation tasks, this paper introduces a semi-supervised learning method to solve the limitations of current PEAT segmentationmethods. In this paper, we propose a difference-guided collaborative mean teacher (DCMT) semi-supervised method, designed for the segmentation of PEAT from DCMT consists of two main components: a semi-supervised framework with a difference fusion strategy and a backbone network MCM-UNet using Mamba-CNN mixture (MCM) blocks. The differential fusion strategy effectively utilizes the uncertain areas in unlabeled data, encouraging the model to reach a consensus in predictions across these difficult-to-segment yet information-rich areas. In addition, considering the sparse and scattered distribution of PEAT in cardiac MR images, which makes it challenging to segment, we propose MCM-UNet as the backbone network in our semi-supervised framework. This not only enhances the processing ability of global information, but also accurately captures the detailed local features of the image, which greatly improves the accuracy of PEATsegmentation. Our experiments conducted on the MRPEAT dataset show that our DCMT method outperforms existing state-of-the-art semi-supervised methods in terms of segmentation accuracy. These findings underscore the effectiveness of our approach in handling the specific challenges associated with PEATsegmentation. The DCMT method significantly improves the accuracy of PEAT segmentation in cardiac MR images. By effectively utilizing uncertain areas in the data and enhancing feature capture with the MCM-UNet, our approach demonstrates superior performance and offers a promising solution for semi-supervised learning in medical image segmentation. This method can alleviate the extensive annotation requirements typically necessary for training accurate segmentation models in medicalimaging.

Automated diagnosis of brain tumor classification and segmentation of magnetic resonance imaging images

<span lang="EN-US">Brain tumors are one of the most prevalent disorders of the central nervous system and are dangerous. For patients to receive the best treatment, early diagnosis is crucial. For radiologists to correctly detect brain tumor images, an automated approach is required. The identification procedure can be time-consuming and prone to mistakes. In this work, the issue of fully automated brain tumor classification and segmentation of magnetic resonance imaging (MRI) including meningioma, glioma, pituitary, and no tumor is taken into consideration. In this study, convolutional neural network (CNN) and mask region-based convolutional neural network (R-CNN) are proposed for classification and segmentation problems respectively. This study employed 3,200 images as a training set and the system achieved an accuracy of 96% for classifying the tumors and 94% accuracy in segmentation of tumors.</span>

St-RegSeg: an unsupervised registration-based framework for multimodal magnetic resonance imaging stroke lesion segmentation.

Stroke is one of the leading causes of disability and death worldwide. Ischemic stroke accounts for 75-90% of all stroke incidents. Assessing the size and location of the stroke lesion is crucial for treatment decisions, especially those related to urgent vascular reconstruction surgery. Magnetic resonance imaging (MRI) offers excellent soft tissue contrast and multimodal imaging characteristics, which can reflect changes in the physiological functions of brain soft tissues in patients with ischemic stroke. However, using deep learning (DL) techniques for MRI segmentation of stroke lesions still faces many challenges. On the one hand, single-modal segmentation models cannot effectively integrate multimodal information; on the other hand, there is a semantic content drift between multimodal stroke MRI images, leading to lower accuracy in subsequent multimodal image segmentation. To address these issues, we aimed to propose the stroke unsupervised registration and segmentation (St-RegSeg) framework. The St-RegSeg framework integrates an unsupervised registration model, ConvNXMorph, and a segmentation model, nnUNet-v2, enabling both registration and segmentation of multimodal MRI images. The St-RegSeg framework was evaluated on the ISLES'22 dataset from three centers. The St-RegSeg framework demonstrated significant improvements in performance metrics and computational efficiency. Compared to advanced normalization tools (ANTs) [symmetric normalization (SyN)] + nnUNet-v2, the St-RegSeg framework improved the Dice similarity coefficient (DSC) by 25.31% in the registration phase, reduced mean squared error (MSE) by 17.36%, increased normalized cross-correlation (NCC) by 16.06%, and enhanced mutual information (MI) by 17.09%. Additionally, in the segmentation phase, it increased the DSC by 0.84%, and the overall inference speed was increased by 40.91 times. Compared to the suboptimal TransMorph + nnUNet-v2, the St-RegSeg framework improved the DSC by 3.68% in the registration phase, reduced MSE by 8.91%, increased NCC by 8.49%, enhanced MI by 6.18%, and in the segmentation phase, it raised the DSC by 0.5%, with the overall inference speed increased by 2.13 times. The St-RegSeg framework provides a highly effective solution for the registration and segmentation of multimodal MRI images in ischemic stroke cases. Its performance metrics and computational efficiency significantly outperform existing methods, making it a promising tool for clinical applications. The code is open-sourced and available at: https://github.com/Cooper-Gu/St-RegSeg.

Hybrid improved fuzzy C-means and watershed segmentation to classify Alzheimer’s using deep learning

Brain damage and deficits in interactions among brain cells are the primary causes of dementia and Alzheimer’s disease (AD). Despite ongoing research, no effective medications have yet been developed for these conditions. Therefore, early detection is crucial for managing the progression of these disorders. In this study, we introduce a novel tool for detecting AD using non invasive medical tests, such as magnetic resonance imaging (MRI). Our method employs fuzzy C-means clustering to identify features that enhance image accuracy. The standard fuzzy C-means algorithm has been augmented with fuzzy components to improve clustering performance. This enhanced approach optimizes segmentation by extracting image information and utilizing a sliding window to calculate center coordinates and establish a stable group matrix. These critical features are subsequently integrated with a two-phase watershed segmentation process. The resulting segmented images are then used to train an optimal convolutional neural network (CNN) for AD classification. Our methodology demonstrated a 98.20% accuracy rate in the detection and classification of segmented MRI brain images, highlighting its efficacy in identifying disease types.

Innovative multi-class segmentation for brain tumor MRI using noise diffusion probability models and enhancing tumor boundary recognition

Medical imaging, notably Magnetic Resonance Imaging (MRI), plays a vital role in contemporary healthcare by offering detailed insights into internal structures. Addressing the escalating demand for precise diagnostics, this research focuses on the challenges of multi-class segmentation in MRI. The proposed algorithm integrates diffusion models, capitalizing on their efficacy in capturing microstructural details, emphasizing the intricacies of human anatomy and tissue variations that challenge segmentation algorithms. Introducing the Diffusion Model, previously successful in various applications, the research applies it to medical image analysis. The method employs a two-step approach: a diffusion-based segmentation model and a dedicated network for enhancing tumor (ET) boundary recognition. Training is guided by a combined loss function, emphasizing Weighted Cross-Entropy and Weighted Dice Loss. Experiments, conducted using the BraTS2020 dataset for brain tumor segmentation, showcase the proposed algorithm’s competitive results, particularly in enhancing accuracy for the challenging ET region. Comparative analyses underscore its superiority over existing methods, emphasizing efficiency and simplicity in clinical implementation. In conclusion, this research pioneers an innovative approach that combines diffusion models and ET boundary recognition to optimize multi-class segmentation for brain tumors. The method holds promise for improving clinical diagnosis and treatment planning, providing accurate and interpretable segmentation results without the need for high-end equipment.

Multimodal Brain Tumor Segmentation Based on Multi-Scale Feature Extraction Network

Brain tumors are prevalent and highly fatal conditions, making their precise detection crucial for effective treatment. Accurate brain tumor segmentation in magnetic resonance imaging (MRI) scans is often crucial for clinical diagnosis and developing more precise treatment strategies. MRI, a standard diagnostic tool for brain tumor identification, offers multiple modalities, each providing unique imaging characteristics. However, existing deep learning-based segmentation methods often struggle with varying tumor size, which can impact their effectiveness. To address these issues, we incorporate DeepLabv3+ into the task of brain tumor segmentation, leveraging its Atrous convolutional capabilities to capture comprehensive multi-scale features. By combining the multi-scale feature extraction strengths of DeepLabV3+ with the diverse imaging modalities of MRI, our approach mitigates the limitations associated with single-scale analysis, thereby enhancing diagnostic accuracy and supporting improved therapeutic outcomes. This article finds that this model achieves an accuracy of approximately 93.5% on the BraTS_2020 dataset.

Accuracy of an nnUNet neural network for the automatic segmentation of intracranial aneurysms, their parent vessels and major cerebral arteries from magnetic resonance imaging-Time of flight (MRI-TOF).

To develop a new machine-learning algorithm for fully automatic identification of cerebral arteries and intracranial aneurysms (IAs) based on a manually segmented magnetic resonance imaging with time-of-flight sequences (MRITOF) dataset. In this retrospective single-center study, 62 MRI-TOF scans of a total of 73 untreated unruptured IAs were manually color-labelled in 21 classes. A nnUNet architecture was trained on MRI-TOF images. The performance of the automatic segmentation was compared with the manual segmentation using Dice Similarity Coefficient (DSC), Centerline Dice (ClDice) and 95th percentile Hausdorff Distance (HD95). Sensitivity was computed for aneurysm detection. Across all 21 classes, the median DSC was 0.86 [95CI: 0.81, 0.89], the median ClDice 0.91 [0.85, 0.94] and the median HD95 was 2.9 [1.0, 14.9] mm. Sensitivity of the model for aneurysms detection was 0.8. For this class specifically, a median DSC of 0.88 [0.13, 0.92], median ClDice of 0.89 [0.06, 1.0] and median HD95 of 1.8 [0.58, 81] mm was achieved. The volume of the labelled anatomical structure was the most relevant determinant of accuracy in this model. Median time to predict was 130.6 [60.9, 284.1] seconds. The nnUNet MRI-TOF based algorithm provided a fast and adequate automatic extraction of unruptured intracranial aneurysms, their parent vessels and the most relevant cerebral arteries. Future steps involve the expansion of the training set with the inclusion of more MRI-TOF studies with and without IAs and its incorporation in 3D imaging viewers and treatment prediction. IA = Intracranial Aneurysm; MRI-TOF＝ Magnetic Resonance Imaging - Time of Flight; DSC = Dice-Sørenson Coefficient; ClDice = Centerline Dice; HD95 = 95th Percentile Hausdorff Distance.

Deep learning applied to the segmentation of rodent brain MRI data outperforms noisy ground truth on full-fledged brain atlases

Translational magnetic resonance imaging of the rodent brain provides invaluable information for preclinical drug development. However, the automated segmentation of such images for quantitative analyses is limited compared to human brain imaging mainly due to the inferior anatomical contrast and the resulting less advanced registration and atlasing tools. Here, we investigated the potential of deep learning models for the segmentation of magnetic resonance images of rat brains into an entire set of multiple regions of interest (rather than individual loci), focusing on the development of a robust method that accommodates changes in the input based on differences in animal strain (genotype) and size. Manually generated labels are expensive, so we tested the ability of neural networks to learn brain structures from noisy but inexpensive registration-based labels, allowing very large datasets to be leveraged for training. We compared three distinct model architectures (U-Net, Attention-U-Net and DeepLab) by training them on a dataset of >10,000 magnetic resonance images of rat brains and found that each model was able to segment the entire brain into predefined sets of 29 and 58 regions, respectively, with the Attention U-Net achieving the best performance. The models canceled out unstructured label noise in the imperfect training data to provide smoother and more symmetric segmentations than registration-based labeling, and were more robust when presented with input variations, thus outperforming the noisy ground truth. Our pipeline also includes uncertainty estimation and an explainability mechanism, hence providing features essential for anomaly detection and quality assurance. In summary, our study shows that deep learning models do achieve accurate brain segmentation in high-throughput quantitative preclinical imaging without the need for expensive expert-generated labels.

The diagnostic value of MRI segmentation technique for shoulder joint injuries based on deep learning

This work is to investigate the diagnostic value of a deep learning-based magnetic resonance imaging (MRI) image segmentation (IS) technique for shoulder joint injuries (SJIs) in swimmers. A novel multi-scale feature fusion network (MSFFN) is developed by optimizing and integrating the AlexNet and U-Net algorithms for the segmentation of MRI images of the shoulder joint. The model is evaluated using metrics such as the Dice similarity coefficient (DSC), positive predictive value (PPV), and sensitivity (SE). A cohort of 52 swimmers with SJIs from Guangzhou Hospital serve as the subjects for this study, wherein the accuracy of the developed shoulder joint MRI IS model in diagnosing swimmers’ SJIs is analyzed. The results reveal that the DSC for segmenting joint bones in MRI images based on the MSFFN algorithm is 92.65%, with PPV of 95.83% and SE of 96.30%. Similarly, the DSC for segmenting humerus bones in MRI images is 92.93%, with PPV of 95.56% and SE of 92.78%. The MRI IS algorithm exhibits an accuracy of 86.54% in diagnosing types of SJIs in swimmers, surpassing the conventional diagnostic accuracy of 71.15%. The consistency between the diagnostic results of complete tear, superior surface tear, inferior surface tear, and intratendinous tear of SJIs in swimmers and arthroscopic diagnostic results yield a Kappa value of 0.785 and an accuracy of 87.89%. These findings underscore the significant diagnostic value and potential of the MRI IS technique based on the MSFFN algorithm in diagnosing SJIs in swimmers.

Using CT images to assist the segmentation of MR images via generalization: Segmentation of the renal parenchyma of renal carcinoma patients.

Developing deep learning models for segmenting medical images in multiple modalities with less data and annotation is an attractive and challenging task, which was previously discussed as being accomplished by complex external frameworks for bridging the gap between different modalities. Exploring the generalization ability of networks in medical images in different modalities could provide more simple and accessible methods, yet comprehensive testing could still be needed. To explore the feasibility and robustness of using computed tomography (CT) images to assist the segmentation of magnetic resonance (MR) images via the generalization, in the segmentation of renal parenchyma of renal cell carcinoma (RCC) patients. Nephrographic CT images and fat-suppressed T2-weighted (fs-T2W) images were retrospectively collected. The pure CT dataset included 116 CT images. Additionally, 240 MR images were randomly divided into subsets A and B. From subset A, three training datasets were constructed, each containing 40, 80, and 120 images, respectively. Similarly, three datasets were constructed from subset B. Subsequently, datasets with mixed modality were created by combining these pure MR datasets with the 116 CT images. The 3D-UNET models for segmenting the renal parenchyma in two steps were trained using these 13 datasets: segmenting kidneys and then the renal parenchyma. These models were evaluated in internal MR (n=120), CT (n=65) validation datasets, and an external validation dataset of CT (n=79), using the mean of the dice similarity coefficient (DSC). To demonstrate the robustness of generalization ability over different proportions of modalities, we compared the models trained with mixed modality in three different proportions and pure MR, using repeated measures analysis of variance (RM-ANOVA). We developed a renal parenchyma volume quantification tool by the trained models. The mean differences and Pearson correlation coefficients between the model segmentation volume and the ground truth segmentation volume were calculated for its evaluation. The mean DSCs of models trained with 116 data in CT in the validation of MR were 0.826, 0.842, and 0.953, respectively, for the predictions of kidney segmentation model on whole image, renal parenchymal segmentation model on kidneys with RCC and without RCC. For all models trained with mixed modality, the means of DSC were above 0.9, in all validations of CT and MR. According to the results of the comparison between models trained with mixed modality and pure MR, the means of DSC of the former were significantly greater or equal to the latter, at all three different proportions of modalities. The differences of volumes were all significantly lower than one-third of the volumetric quantification error of a previous method, and the Pearson correlation coefficients of volumes were all above 0.96 on kidneys with and without RCC of three validations. CT images could be used to assist the segmentation of MR images via the generalization, with or without the supervision of MR data. This ability showed acceptable robustness. A tool for accurately measuring renal parenchymal volume on CT and MR images was established.

Evaluation of registration-based vs. manual segmentation of rhesus macaque brain MRIs.

With increasing numbers of magnetic resonance imaging (MRI) datasets becoming publicly available, researchers and clinicians alike have turned to automated methods of segmentation to enable population-level analyses of these data. Although prior research has evaluated the extent to which automated methods recapitulate "gold standard" manual segmentation methods in the human brain, such an evaluation has not yet been carried out for segmentation of MRIs of the macaque brain. Macaques offer the important opportunity to bridge gaps between microanatomical studies using invasive methods like tract tracing, neural recordings, and high-resolution histology and non-invasive macroanatomical studies using methods like MRI. As such, it is important to evaluate whether automated tools derive data of sufficient quality from macaque MRIs to bridge these gaps. We tested the relationship between automated registration-based segmentation using an open source and actively maintained NHP imaging analysis pipeline (AFNI) and gold standard manual segmentation of 4 structures (2 cortical: anterior cingulate cortex and insula; 2 subcortical: amygdala and caudate) across 37 rhesus macaques (Macaca mulatta). We identified some variability in the strength of correlation between automated and manual segmentations across neural regions and differences in relationships with demographic variables like age and sex between the two techniques.

A deep learning approach for cervical cord injury severity determination through axial and sagittal magnetic resonance imaging segmentation and classification.

Cross-sectional Database Study. While the American Spinal Injury Association (ASIA) Impairment Scale is the standard for assessing spinal cord injuries (SCI), it has limitations due to subjectivity and impracticality. Advances in machine learning (ML) and image recognition have spurred research into their use for outcome prediction. This study aims to analyze deep learning techniques for identifying and classifying cervical SCI severity from MRI scans. The study included patients with traumatic and nontraumatic cervical SCI admitted from 2019 to 2022. MRI images were labeled by two senior resident physicians. A deep convolutional neural network was trained using axial and sagittal cervical MRI images from the dataset. Model performance was assessed using Dice Score and IoU to measure segmentation accuracy by comparing predicted and ground truth masks. Classification accuracy was evaluated with the F1 Score, balancing false positives and negatives. In the axial spinal cord segmentation, we achieved a Dice score of 0.94 for and IoU score of 0.89. In the sagittal spinal cord segmentation, we obtained Dice score up to 0.9201 and IoU scores up to 0.8541. The model for axial image score classification gave a satisfactory result with an F1 score of 0.72 and AUC of 0.79. Our models successfully identified cervical SCI on T2-weighted MR images with satisfactory performance. Further research is needed to develop more advanced models for predicting patient outcomes in SCI cases.