Period Of Movement Research Articles

Sleep schedules and MSLT-based diagnosis of narcolepsy type 2 and idiopathic hypersomnia: Exploring potential associations in a large clinical sample.

Differential diagnosis of narcolepsy type 2 and idiopathic hypersomnia relies on the frequency of sleep-onset rapid eye movement periods observed on the Multiple Sleep Latency Test. This study investigated whether variations in sleep schedules, particularly delayed sleep-wake patterns, contribute to the diagnostic distinction between narcolepsy type 2 and idiopathic hypersomnia. The study included 871 patients aged 18-39 years (316 with narcolepsy type 2, 555 with idiopathic hypersomnia). These patients were diagnosed based on MSLT results following polysomnography from November 2013 to November 2017. Patients' sleep habits, including bedtime and wake-up times on weekdays and weekends during the 2 weeks preceding the polysomnography/Multiple Sleep Latency Test, were assessed using self-reported sleep logs. A multivariate logistic regression analysis was conducted to identify factors associated with narcolepsy type 2 diagnosis. The analysis revealed that being male (p < 0.001), younger age (p < 0.001), shorter weekday sleep duration (p < 0.05), and a delayed weekday sleep midpoint time (p < 0.01) were significantly associated with a diagnosis of narcolepsy type 2. The study suggests that the conventionally fixed schedule of polysomnography and Multiple Sleep Latency Test administration may have contributed to the increased occurrence of sleep-onset rapid eye movement periods particularly in individuals with a delayed sleep-wake schedule.

HISTORIOGRAPHY OF THE ESSENCE OF THE CONFLICTING POLICY OF THE SOVIET ERA ON WOMEN'S ISSUES IN THE HISTORY OF UZBEKISTAN

In this article, it is emphasised that the study of the treatment of women in the history of Uzbekistan and the nature and evolution of the women's movement, women's organisations and the state of the women's movement in the present period is of urgent importance from the point of view of historiography. It is the comparative analysis of the state policy regarding the treatment of women during the period of the former Soviet Union and the years of independence that allows us to understand the colonial nature of the Soviet policy fully. The article analyses the historiography of the topic. ‎

Crustal silica content of East China: A seismological perspective and its significance

East China has experienced multiple periods of tectonic movements, which have contributed to the composition and rheological properties of its present crust. Estimating the composition of the crust is crucial for understanding the tectonic processes. Based on the teleseismic receiver functions with data from the National Seismic Network of China, we applied the H-κ-c method to obtain the crustal bulk VP/VS ratio and to constrain the SiO2 content in the crust. We estimated the SiO2 content to range from 50.89 wt% to 73.51 wt%, with an average value of 65.87 wt%, indicating a predominant felsic composition of the East China's crust. Our study suggests that the North-South Gravity Lineament (NSGL) is an approximate delimitator of the felsic and mafic crust in East China, hinting at a widespread deficiency of mafic lower crust in the east of the NSGL. The mafic crust is extensively distributed in the Taihang orogenic region (TSR) and WuLingshan gravity gradient belts (WLG), particularly in the Datong volcanic area, which manifests the mantle materials intraplating. The scatteredly distributed mafic crust at the east of the NSGL is mainly concentrated in the southeast coast of China and in the intersection region of the Tanlu Fault (TLF) and Sulu region. In Sulu region, the TLF may primarily provide a channel for the thermal intrusion from the underlying mantle lithosphere, which has increased the mafic content. The Pacific/Philippine Sea plate subduction has triggered a significant amount of crust-mantle material exchange below southeast China that resulted in a high degree of mafic crustal composition.

Substantiation of rational design parameters of a crusher with two movable jaws

Purpose. Design engineering of the mechanism of a two-jaw crusher with a compound motion of the jaws, which ensures a change in the angle of gripping of pieces of material within a very small range. Methodology. In the work, a theoretical study on the fourth-class lever mechanism, as the basis of a two-jaw crusher, was performed using the Mathcad 15 software. The study was performed on a vector representation of the links of the hinged mechanism. The development and analysis of constructive solutions were performed using the Autocad software product, which reduces the risk of errors and increases the quality of the design process. Findings. The paper theoretically determines the rational geometric parameters of the two-jaw crusher with the optimal value of the nip angle, whose crushing chamber is formed by the closed loop circuit of the flat fourth-class lever mechanism and proposes a new constructive solution of the mechanism for adjusting the crusher opening with two movable jaws and the bottom mounting of eccentric nodes. The developed device in the form of separate blocks is made with the possibility of their simple assembly and disassembly, which ensures the rate and quality of replacing lining plates or surfacing restoration of the worn working surface of the jaws. The relative movement of the jaws ensures the crushing of pieces of material with the required crushing coefficient. The geometric parameters were obtained by the method of kinematic synthesis. The geometric parameters of the crushing chamber of the two-jaw crusher were determined theoretically; the dependence was obtained of the change in the nip angle on the height of the movable jaw over a period of movement and the change in the compression stroke, which ensures the force interaction of the working surface of the jaws with the material. Originality. It is proved that the quadrilateral closed circuit of the fourth-class lever mechanism can be used as a crushing chamber of a two-jaw crusher. Two links of a closed circuit operate as jaws which break pieces of material. At the same time, the nip angle can vary within fairly narrow limits, ensuring the optimality of the crushing process. It was established that the considered option of the fourth-class six-link mechanism geometry has only two folds. An algorithm is presented for searching for assemblies with the purpose of identifying those that are closely adjacent. Practical value. The results of the conducted research provide the theoretical background and the algorithm for determining the optimal parameters of a two-jaw crusher which can be used at the stage of designing similar crushers. The developed design solution for adjusting the crusher opening expands the scope of application of double-jaw crushers. The obtained dependences of the change in the angle of inclination and the working surface of the jaw over a period make it possible to develop a rational mode of crushing the material

The Construction and Changes of Railway Cognition in Manchuria During the Boxer Movement Period

During the Boxer Movement, the railroads were seen as a major object of contention and a place of conflict by both Chinese and Russian Empire parties, but there were significant differences in the perception of the railroads. Foreign countries, especially Russian Empire, viewed the railroads as an important means of transportation with modern technology and expected them to be successfully built and opened to traffic, and the Russian Empire army viewed them as an important force. On the Chinese side, the laborers saw the railroads only as an opportunity to support their families and lacked an understanding of their modern technological value. Qing officials and the Boxers were adamant that the railroads be dismantled, seeing them as detrimental to their own army and rejecting and destroying them as foreign symbols. The Manchuria region's awareness of railroads and modern technology at the time was significantly lower than that of other regions in China that were actively developing modern technology and industry at the same time.

Performance control during longitudinal activation fMRI studies.

The documentation of performance during functional imaging represents a standard procedure employed to control for compliance, sensorimotor, and cognitive demands. In the case of motor tasks, preciseness, force, and frequency have a significant impact on the magnitude of functional activation. Questionnaires are used in psychological investigations to control for cognitive demand, while psychophysiological documentation is employed to record bodily responses. For longitudinal intervention studies, it is of utmost importance to implement meticulous pre- and post-performance controls and balance to accurately assess changes over time. Any changes in compliance may introduce additional uncontrolled variables, which can hinder the interpretation of functional magnetic resonance imaging (fMRI)-related changes. This narrative review presents strategies for controlling and balancing performance in functional imaging approaches to document neuroplasticity in rehabilitative studies. These strategies include not only motor-related aspects, such as precision, velocity, and force, but also timing aspects, such as the start and stop of movement periods. In addition, it discusses strategies for the modulation and control of movement aspects with visual feedback, as well as for the control of physiological changes during experimental modulation. Although these measures require additional care, which is often more demanding than the neuroimaging part of the study, they are crucial for a relevant interpretation and publication of fMRI studies.

Gross movement counting of fetuses conceived with assisted reproductive technology using a fetal movement acceleration measurement recorder

To investigate whether assisted reproductive technology (ART) affects gross fetal movement. A prospective cohort study. 65 women who conceived with ART (ART group) and 211 women (control group) without ART recorded fetal movement with the fetal movement acceleration measurement recorder at night weekly after 28 weeks. The number ratio of 10 s epochs with fetal movement to all epochs was calculated as the fetal movement parameter. When no fetal movement was observed for more than 5 min, it was defined as a no fetal movement period, and the average number per hour, the average duration, and the longest duration of the no fetal movement periods were calculated as the no fetal movement parameters. Gestational weeks were classified into 28–33 and 34–39 weeks, and the fetal movement parameter and the no fetal movement parameters were compared using the Student’s t-test. The fetal movement parameters at 28–33 weeks were 17.43% (ART) and 16.58% (control) (p = 0.219), and those at 34–39 weeks were 11.72% (ART) and 11.96% (control) (p = 0.590). In the same way, for the no fetal movement parameters, the average numbers were 1.58 and 1.63 per hour (p = 0.357), and 2.36 and 2.30 per hour (p = 0.503). The average durations were 8.30 and 8.46 min (p = 0.712), and 9.20 and 9.51 min (p = 0.188). The longest durations were 16.26 and 17.02 min (p = 0.295), and 22.34 and 22.87 min (p = 0.534). ART does not affect gross fetal movement count.

Sub‐Pixel Displacement Estimation With Deep Learning: Application to Optical Satellite Images Containing Sharp Displacements

AbstractOptical image correlation is a powerful method for remotely constraining ground movement from optical satellite imagery related to natural disasters (e.g., earthquakes, volcanoes, landslides). This approach enables the characterization, and identification of the causal factors and mechanisms underlying such processes. By employing sub‐pixel correlation algorithms, one can obtain highly accurate (m‐to‐cm level) displacement fields at high spatial resolution (dm‐to‐cm) by comparing satellite images acquired before and after a period of movement. However, this method generally assumes a homogeneous translation of all pixels within a given correlation window, which will lead to biased estimates of ground displacement if the real case is not well represented by such a simplification, especially when resolving ground displacements next to sharp gradients in displacement, such as those found in the near‐field of earthquake surface ruptures. In this paper, we present an innovative deep learning method estimating sub‐pixel displacement maps from optical satellite images for the retrieval of ground displacement. From the generation of a realistic simulated database, comprising Landsat‐8 satellite image pairs containing simulated sub‐pixel shifts and sharp discontinuities, we develop a Convolutional Neural Network able to retrieve sub‐pixel displacements. The comparison to state‐of‐the‐art correlation methods shows that our pipeline significantly reduces by 32% the estimation bias around fault ruptures, leading to more accurate characterization of the near‐field strain in surface rupturing earthquakes. Application of our model to the 2019 Ridgecrest earthquake demonstrates the ability of our model to accurately and quickly resolve ground displacement using real satellite images. Code is made available at https://gricad‐gitlab.univ‐grenoble‐alpes.fr/montagtr/cnn4l‐discontinuities.

Energy firms in China towards resilience: A dynamic quantile connectedness approach

Α comprehensive understanding of the energy and technology sectors is imperative for the implementation of effective climate and industrial policies. This study investigates the quantile interconnectedness between the top five energy equities and the top five technology equities, listed on the Shanghai Stock Exchange 50 Index (SSE50), based on market capitalization. Employing the Quantile VAR methodology, we uncover significant interconnectedness across various quantiles of the return distribution for both energy and technology equities. This implies that price fluctuations within one sector can have a significant effect on the other. Furthermore, our analysis reveals directional connectedness, where energy equities consistently influence technology equity prices throughout the entire period of investigation. Additionally, a heightened degree of interconnectedness is observed during periods of extreme market movements, i.e. in the upper and lower tails of the return distribution. This suggests a more integrated system during stressed conditions, where all equities under investigation exhibit a magnified influence on each other, potentially leading to amplified volatility spillovers. These findings provide valuable insights for investors, portfolio managers, and policymakers, enabling them to develop more informed investment strategies and construct robust risk management frameworks.

Noninvasive brain stimulation during EEG improves machine learning classification in chronic stroke.

In individuals with chronic stroke and hemiparesis, noninvasive brain stimulation (NIBS) may be used as an adjunct to therapy for improving motor recovery. Specific states of movement during motor recovery are more responsive to brain stimulation than others, thus a system that could auto-detect movement state would be useful in correctly identifying the most effective stimulation periods. The aim of this study was to compare the performance of different machine learning models in classifying movement periods during EEG recordings of hemiparetic individuals receiving noninvasive brain stimulation. We hypothesized that transcranial direct current stimulation, a form of NIBS, would modulate brain recordings correlating with movement state and improve classification accuracies above those receiving sham stimulation. Electroencephalogram data were obtained from 10 participants with chronic stroke and 11 healthy individuals performing a motor task while undergoing transcranial direct current stimulation. Eight traditional machine learning algorithms and five ensemble methods were used to classify two movement states (a hold posture and an arm reaching movement) before, during and after stimulation. To minimize compute times, preprocessing and feature extraction were limited to z-score normalization and power binning into five frequency bands (delta through gamma). Classification of disease state produced significantly higher accuracies in the stimulation (versus sham) group at 78.9% (versus 55.6%, p < 0.000002). We observed significantly higher accuracies when classifying stimulation state in the chronic stroke group (77.6%) relative to healthy controls (64.1%, p < 0.0095). In the chronic stroke cohort, classification of hold versus reach was highest during the stimulation period (75.2%) as opposed to the pre- and post-stimulation periods. Linear discriminant analysis, logistic regression, and decision tree algorithms classified movement state most accurately in participants with chronic stroke during the stimulation period (76.1%). For the ensemble methods, the highest classification accuracy for hold versus reach was achieved using low gamma frequency (30-50 Hz) as a feature (74.5%), although this result did not achieve statistical significance. Machine learning algorithms demonstrated sufficiently high movement state classification accuracy in participants with chronic stroke performing functional tasks during noninvasive brain stimulation. tDCS improved disease state and movement state classification in participants with chronic stroke.

Effects and mechanisms of electroacupuncture on fear extinction and sleep phase in single prolonged stress mice

To observe the effects of electroacupuncture (EA) on fear extinction and sleep phase in single prolonged stress (SPS) mice, and explore its mechanism in view of the expression of relevant synaptic proteins. Thirty-two C57BL/6J male mice were randomly divided into a control group, a model group, an EA group and a paroxetine (PRX) group, with 8 mice in each one. Modified SPS method was used to establish PTSD model in the model group, the EA group and the PRX group. Seven days after modeling completion, in the EA group, the intervention was delivered at "Baihui" (GV 20) and bilateral "Zusanli" (ST 36), with disperse-dense wave, 3 Hz/15 Hz in frequency and 1 mA in current intensity, for 30 min. In the PRX group, paroxetine solution (2.5 g/L) was administered intragastrically (10 mg/kg). The intervention was given once daily and for consecutive 10 days in the above two groups. The fear conditioning task and the elevated plus-maze test were adopted to evaluate the fear extinction and anxiety of the mice in each group. Using Medusa electroencephalogram (EEG) and electromyography (EMG) recording system from rats and mice, the sleep phase was determined in the mice. With Western blot method adopted, the protein expression of the postsynaptic density protein 95 (PSD95), activity-regulated cytoskeleton-associated protein (ARC), brain-derived neurotrophic factor (BDNF), N-methyl-D-aspartic acid receptor 2A (GluN2A), N-methyl-D-aspartic acid receptor 2B (GluN2B) and alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor 1 (GluA1) in the hippocampus was detected in the mice. Compared with the control group, the freezing time for the fear re-exposure in 3 min to 15 min and the fear extinction in 0 min to 3 min were prolonged (P<0.05), the fear extinction index decreased (P<0.05), and the open arm time (OT) of the elevated plus-maze was shortened (P<0.05) in the model group. When compared with the model group, in the EA group and the PRX group, the freezing time for the fear re-exposure in 3 min to 6 min and 12 min to 15 min, as well as the fear extinction in 0 min to 3 min was shortened (P<0.05), the fear extinction index increased (P<0.05); the OT in elevated plus-maze was longer in the mice of the EA group (P<0.05). The period of wake (Wake) was prolonged (P<0.05), the non-rapid eye movement period (NREM) and the total sleep time (Sleep) were reduced in the model group (P<0.05) in comparison with the control group. Compared with the model group, the Wake was declined (P<0.05), and the NREM and Sleep increased in the EA group and the PRX group (P<0.05). When compared with the control group, the protein expression of PSD95, ARC, BDNF, GluN2A and GluA1 in the hippocampus decreased (P<0.05), and that of GluN2B increased (P<0.05) in the model group. In the EA group and the PRX group, the protein expression of PSD95, ARC, BDNF, GluN2A and GluA1 in the hippocampus was elevated (P<0.05), and that of GluN2B reduced (P<0.05) when compared with the model group. Electroacupuncture at "Baihui" (GV 29) and "Zusanli" (ST 36) can ameliorate anxiety-like behavior, fear extinction disorder and abnormal sleep phase in SPS mice, which may be related to the regulation of synaptic transmission and synaptic plasticity expression in the hippocampus.

Analysis of the periodicity of movements of mechanisms with elastic links of variable length

Abstract Elastic dynamic systems with open kinematic chains are effectively described by a recursive model of the generalized Newton–Euler method with the provision of computational algorithms with a degree of complexity proportional to the dimension of these systems, i.e. O(n). Such systems, in particular, are elastic manipulators, some of which are discussed in this article. In the case when elastic dynamical systems have closed kinematic circuits, the application of a numerical analysis strategy without reversing the mass matrix is extremely difficult. The analysis of the simplest type of elastic mechanisms with closed circuits, such as a crank–slide mechanism and a four–pin mechanism with elastic connecting rods, revealed a peculiar picture of the periodicity of the functions of elastic movements of connecting rods, which differs significantly from the periods of operation of the mechanisms themselves. In this article, the properties of the periodicity (or pseudo-periodicity) of the elastic displacement function of mechanisms with elastic links of variable length are investigated using examples of numerical dynamic analysis of crank–rocker mechanisms.

Origin of facies-controlled dolomite and exploration significance of the Middle Permian Qixia Formation in central Sichuan Basin, Western China

The intraplatform shoal dolomite of the Middle Permian Qixia Formation is currently considered the key target of hydrocarbon exploration in the central Sichuan Basin. To systematically investigate the origin of the stratabound facies-controlled porous dolomites of the Qixia Formation, integrated petrography, logging and seismic analysis were carried out in this work. The results are as following: (1) the dolomite reservoir is universal in the central Sichuan Basin, and its distribution is controlled by intraplatform shoals, with multilayer superposition vertically. Thick massive dolostone may also develop along with the fault. (2) Three replaced dolomites and one dolomite cement were identified: very finely to finely crystalline, anhedral to subhedral dolomite (Rd1); finely to medium crystalline, anhedral to subhedral dolomite (Rd2); coarsely crystalline, subhedral to euhedral dolomite (Rd3) and coarsely crystalline saddle dolomite cement (Sd). Rd2 and Rd3 are partly fabric-retentive, and preserve the original bioclastic ghosts. Sd shows wavy extinction, filled in the breccia veins. (3) The U-Pb dating and homogenization temperatures results indicate that the dolomite and Sd cement are associated with hydrothermal event during the Emeishan large igneous province. The δ13C, 87Sr/86Sr, and seawater-like REEY patterns suggest that the dolomitization and Sd precipitation fluids originate from connate seawater heated by elevated heat-flow. (4) The ELIP triggered large scale thermal anomalies in the basin during the Dongwu movement period. The increased temperature and pressure drove the formation water in the intra-platform shoal facies and overcame the binding effect of Mg2+ hydrate. Moreover, the deep hydrothermal fluid preferentially penetrated into the porous strata of shoal facies along the faults and fractures, mixed with formation water to some extent, and extensive dolomitization occurred. The facies-controlled dolomite reservoir and the underlying Cambrian source rock form a good source-reservoir assemblage, which can be a key replacement option.

Postoperative pain management following minimally invasive abdominal cancer surgeries -An audit.

There is limited data comparing pain management following various minimally invasive oncological surgeries (MIOS). This retrospective audit was planned to determine the severity of pain and to study the analgesic modalities offered to these patients. Secondary objectives included studying opioid requirements, non-opioid analgesics, their side effects, and the influence of comorbidities on the choice of pain modalities. Following approval and registration of trial (CTRI/2018/10/016220), data were collected retrospectively from adult patients who underwent elective MIOS for abdominal tumors from August 2017 to July 2018. Pain scores (PS) on the day of surgery, and the average, worst PS, and the morphine equivalent (ME) dose in the perioperative period was recorded. Emergency surgeries and thoracic-abdominal MIOS were excluded. The association between the type of surgery, pain modalities, and PS were compared using Chi-square test. ME dose consumption of patients and type of surgery were compared using ANOVA with Bonferroni's correction. Out of the 349 patients' data that were analyzed, 76% had mild, 22% had moderate, and 2% had severe pain after surgery. Port site infiltration was done in 27% of cases and epidural analgesia in 46 patients (13%). PS and opioid consumption (ME = 5.7 ± 5.2 mg) was significantly higher following pelvic surgeries when compared to other urological and diagnostic MIOS. American Society of Anesthesiologists Physical Status did not affect PS or choice of pain management technique. Most of the patients experience mild pain at movement in the immediate postoperative period, pelvic MIOS (abdominoperineal resection/exenteration surgeries) have higher PS and opioid consumption than other MIOS.

Simulation of lower Cambrian oil and gas generation and phase evolution process in ZH1 of Tazhong area

The Lower Cambrian petroleum system in the Tarim Basin has undergone multiple periods of tectonic movements, leading to successive hydrocarbon expulsion events and adjustments. The complex process of hydrocarbon accumulation occurred under deep burial conditions, persisting at depths of nearly 6,000 m over an extended period. This has resulted in the current occurrence of various phases including light oil, condensate, and gas in the deep-ultradeep strata of the Tarim Basin. The intricacies of formation of hydrocarbon accumulations and phase evolution have posed challenges to understanding the accumulation mechanisms and enrichment patterns of the Cambrian in the Tarim Basin, consequently lowering the success rate of oil and gas exploration. Such characteristics of multi-stage accumulation and adjustment are prevalent in deep hydrocarbon systems. Therefore, based on data from Well ZH1 in the Tazhong Uplift, combined with basin simulation, Compositional kinetics model, and PVT performance simulation, this study investigates the hydrocarbon generation and phase evolution processes in the deep hydrocarbon systems of the Tazhong Uplift. The results indicate that Well ZH1 entered the hydrocarbon generation peak during the Late Ordovician, followed by secondary cracking as the predominant hydrocarbon evolution process. Hydrocarbon fluids within the Lower Cambrian reservoir transitioned into the condensate phase towards the end of the Cambrian, with increasing depth resulting in higher gas-oil ratios and a decreasing trend in viscosity and density.

Human Cervical Epidural Spinal Electrogram Topographically Maps Distinct Volitional Movements.

Little is known about the electrophysiologic activity of the intact human spinal cord during volitional movement. We analyzed epidural spinal recordings from a total of five human subjects of both sexes during a variety of upper extremity movements and found that these spinal epidural electrograms contain spectral information distinguishing periods of movement, rest, and sensation. Cervical epidural electrograms also contained spectral changes time-locked with movement. We found that these changes were primarily associated with increased power in the theta (4-8 Hz) band and feature increased theta phase to gamma amplitude coupling, and this increase in theta power can be used to topographically map distinct upper extremity movements onto the cervical spinal cord in accordance with established myotome maps of the upper extremity. Our findings have implications for the development of neurostimulation protocols and devices focused on motor rehabilitation for the upper extremity, and the approach presented here may facilitate spatiotemporal mapping of naturalistic movements.

Narcolepsy and rapid eye movement sleep.

Since the first description of narcolepsy at the end of the 19th Century, great progress has been made. The disease is nowadays distinguished as narcolepsy type 1 and type 2. In the 1960s, the discovery of rapid eye movement sleep at sleep onset led to improved understanding of core sleep-related disease symptoms of the disease (excessive daytime sleepiness with early occurrence of rapid eye movement sleep, sleep-related hallucinations, sleep paralysis, rapid eye movement parasomnia), as possible dysregulation of rapid eye movement sleep, and cataplexy resembling an intrusion of rapid eye movement atonia during wake. The relevance of non-sleep-related symptoms, such as obesity, precocious puberty, psychiatric and cardiovascular morbidities, has subsequently been recognized. The diagnostic tools have been improved, but sleep-onset rapid eye movement periods on polysomnography and Multiple Sleep Latency Test remain key criteria. The pathogenic mechanisms of narcolepsy type 1 have been partly elucidated after the discovery of strong HLA class II association and orexin/hypocretin deficiency, a neurotransmitter that is involved in altered rapid eye movement sleep regulation. Conversely, the causes of narcolepsy type 2, where cataplexy and orexin deficiency are absent, remain unknown. Symptomatic medications to treat patients with narcolepsy have been developed, and management has been codified with guidelines, until the recent promising orexin-receptor agonists. The present review retraces the steps of the research on narcolepsy that linked the features of the disease with rapid eye movement sleep abnormality, and those that do not appear associated with rapid eye movement sleep.

Late Quaternary tectonic uplift and Yellow River evolution create high arsenic aquifers in the Hetao Basin, China

High arsenic (As) groundwater is a global problem primarily originating from As-enriched sediments. The provenance (source) and release mechanisms (sinks) of high As sediment have been identified, but the source-sink transfer is poorly understood, especially the influence of geological and surface processes. In this study, we explore the roles of tectonic movement and Yellow River evolution in provenance formation processes and evaluate the combined effects of provenance and sediment age on the As content of aquifer sediments in the northern Hetao Basin of Inner Mongolia. Based on optically stimulated luminescence (OSL) and 14C dating and detrital zircon U-Pb, As content, and lithological analyses of a 400 m core, we reconstructed As changes over the last 160 ka. Our results show clay deposited in a paleo-lake during the Gonghe movement period in the late Pleistocene (∼100 ka B.P.) is enriched in As (31.8 μg/g) due to significant provenance contributions of the As-bearing Langshan Group under tectonic uplift and mountain erosion. In contrast, clay deposited in the middle Pleistocene (∼160 ka B.P.) has lower As content (7.3 μg/g) due to the Yellow River as the primary provenance. Accordingly, the provenance of basin As forced by tectonic uplift and Yellow River evolution determines the background As of aquifer sediments. After deposition, sediment As content decays over time, with higher decay rates in coarse-grained sands than fine-grained. Overall, both provenance formation and sediment age, representing initial and dynamic states of solid phase As, jointly determine the As content of aquifer sediments. More solid phase As provided by younger sediments from the proximal orogenic provenance and reducing conditions due to frequent river–lake transitions, jointly lead to higher As concentrations in shallow groundwater. The study highlights the potential for using a combined analysis of the tectonic movement-surface processes-environment system to improve understanding of geogenic high As groundwater over global large sedimentary basins in the proximity of young orogenic belts.

The Effect of Combination of Cone Drill (Zigzag) with Core Stability, Combination of Ladder Drill (Snake Jump) with Core Stability, and Speed on Agility of Futsal Players: A Factorial Experimental Design

The game of futsal, known for its high intensity and dynamic nature demanding skill and robust physical fitness, particularly in agility, presents a significant challenge. Incorporating variations of cone and ladder drills in agility training, with a focus on enhancing balance through core stability training in conjunction with speed modulation as a key factor, is believed to impact players' agility players. Despite recognizing the individual significance of these training modalities in boosting agility performance, there remains a gap in fully comprehending their combined effects during futsal engagements. This research seeks to scrutinize the group differentials in agility training, factoring in speed variations in relation to futsal players' agility levels. The study defined agility training cohorts as a combo group of cone drill with core stability and a combination group of ladder drill alongside core stability, while speed was categorized as high or low. Employing an experimental methodology with a 2 x 2 factorial design, the study enlisted 20 players aged 17.1 ± 0.76 years through random selection. Agility training, conducted thrice weekly over a six-week period, emphasized swift and dynamic movements alongside maintaining balance. Speed and agility metrics were assessed using the 30m acceleration test and Illinois agility test, then subjected to statistical scrutiny via a two-way ANOVA at a significance level of 0.05. Results revealed that both training methodologies benefited participants with elevated speed (P&lt;0.05). Notably, agility training incorporating ladder drill exercises and core stability training exhibited superior outcomes for high-speed performers (P&lt;0.05). Conversely, individuals with lower speed levels potentially benefitted more from a combination of ladder drill and core stability (P&lt;0.05). These findings furnish crucial insights for futsal coaches and trainers looking to craft tailored training regimens aimed at enhancing agility performance effectively. Keywords: Cone Drill, Ladder Drill, Core Stability, Speed, Agility, Futsal

КОНЦЕПЦИЯ КУЛЬТУРНОГО НАЦИОНАЛИЗМА И ЕЁ РЕАЛИЗАЦИЯ В ИРЛАНДИИ В XIX – НАЧАЛЕ XX ВВ.

In the article, the authors attempt to analyze one of the most important components of the Irish national movement of the 19th – early 20th centuries, cultural nationalism. Irish nationalism throughout its history has tended to variously highlight issues of political liberation or self-government, agrarian and religious issues. Priorities largely depended both on the prevailing ideas of the leaders of the movement in a particular period, and on the corresponding political and social atmosphere. An important role was also played by the commitment of the leaders of nationalist organizations to the methodology for implementing their programs, be it “physical” or “moral strength”. However, the total dictatorship of Britain in imposing English culture, language, traditions, education with severe pressure on Irish culture, demanded from nationalists the formation of the identity of the Irish nation, the renovation of the rich national heritage. With the change in the social state of society at the turn of the 19th and 20th centuries, cultural nationalism gained a huge audience, while updating new directions in culture. The revolution of 1916-1923, while solving the problem of winning independence, also included the problem of national self-identification.