In Iraq, the number of passenger cars, trucks and buses, local generators, and heavy construction equipment rose to a considerable extent since 2003, causing high environmental problems. Many types of pollutants were monitored and recorded for 24 h during March 2016. The study attempts to explore and establish a relationship between the volume of activity and the movement of motor vehicles of various compounds and contaminants resulting from their exhaust pipes, such as sulfur dioxide, particulate matters, oxides of nitrogen, VOCs, and unburned hydrocarbons. The study focused in and around Mohammad Al-Qasim highway adjacent to the University of Technology, Baghdad. The results showed the need for urgent treatments addressed by the environmental authorities in the city. The study results demonstrated that these contaminants are increased during periods of the beginning and end of working hours for government departments. Some types of sulfur compounds (H2S and SO2) concentrations were at serious health-threatening levels, which is a result of the high sulfur content in the Iraqi fuel. The concentrations of NOx and VOC were high, also, which could make the studied area vulnerable to the risk of smog formation. The Iraqi government should make greater efforts to protect the environment and human in this country from the transportation pollution risks.