Morphological Composition Of Blood Research Articles

Morphological composition of blood and phagocytosis indicators in calves obtained from cows with genital mycoplasmosis using various therapeutic regimes

Morphological composition of blood and phagocytosis indicators in calves obtained from cows with genital mycoplasmosis using various therapeutic regimes

Ecotoxicological Assessment of Ponds Contaminated by Wastewater of Livestock Enterprises by Fish Biomarkers

The morphometric characteristics of internal organs, the morphological composition of blood, and indicators of metabolic processes in the blood plasma and hepatopancreas of the two-year-old carp (<i>Cyprinus carpio</i> L.) from the conditionally clean pond and contaminated with sewage from a livestock enterprise pond were examined. It was established that the considered contamination caused increase of the spleen mass and its index respectively 1.63 and 1.65 times, but did not affect live weight, body length and height, body structure index, hepatopancreas mass and its index. The hemoglobin concentration, number of erythrocytes, thrombocytes and monocytes in blood of carps from the contaminated pond was lower than in control, whereas number of the segmented neutrophils and ESR were higher, and the number of leukocytes, eosinophils, lymphocytes and rod-nucleated neutrophils did not differ. Wastewater from the livestock enterprise affected metabolic processes in carp, particularly caused increase of the glucose and total protein concentration, the lactate dehydrogenase, aspartate aminotransferase and creatine kinase activity in blood plasma and hepatopancreas. At the same time, there were no differences between specimens from the conditionally clean and contaminated pond in terms of content of triglycerols, cholesterol, urea, creatinine, calcium, inorganic phosphorus, AlAT and AsAt activity in blood plasma and hepatopancreas and total protein content and LHD activity in hepatopancreas, content of total protein, glucose, creatinine, urea, the glucose content in hepatopancreas. The established changes in internal organs, morphological composition of blood and metabolic parameters, particularly concentration of hemoglobin and the erythrocytes number in blood, glucose and total protein content, and activity of lactate dehydrogenase and creatine kinase in carp enabled to propose to use these parameters as supplementary over assessment of the ecotoxicological state of ponds contaminated by wastewater from livestock enterprises.

Hygienic assessment of the probiotic Bioseven influence on the natural resistance of rabbits pre-clinical researches

Rabbit farming plays an important role in the increase of livestock products, one of the precocious branches of small animal husbandry. From a rabbit and its offspring, more than 100 kg of meat can be obtained per year. The body of rabbits, as well as other agricultural and rural animals. animals, during life is under the influence of abiotic and biotic factors that cause growth depression, changes in the morphological composition of blood, and immunological indicators. The use of biologically active drugs that increase immunological reactivity, stimulating growth, development and resistance deserve attention. The use of probiotic preparations of young animals in the early stages of breeding normalizes the microflora of the gastrointestinal tract, stimulates the synthesis of immunoglobulin IgA, increases its natural resistance, and activates homeostasis. The aim of the work was to carry out a hygienic assessment of the effect of the probiotic Bioseven on the natural resistance of the rabbit's body. The following methods of observation were used to obtain scientific information: biological, hematological, biochemical studies, statistical. The research was conducted on rabbits of the gray giant breed of both sexes. Healthy animals with the appropriate body weight were used in the experiments. Fluctuations in body weight in the respective groups did not exceed ±10.0%. Animals were kept in groups in cages in compliance with sanitary and hygienic requirements. The use of the new domestic biologically active drug (probiotic) Bioseven as a means of preventive action is substantiated in the research paper. The drug has been proven to have a positive effect on the morphological, biochemical and immunological parameters of the blood of animals, increase the natural resistance and growth intensity of rabbits. During morphological studies, it was established that the level of endogenous intoxication of the body of rabbits of experimental groups and controls during the observation period remained stable and amounted to 17.95-18.33% (experimental) and 18.42±0.55 in control, which indicates the absence of a suppressor effects of the probiotic bioseven on the antioxidant properties of the rabbit body in doses: 0.5-5.0 g/head. The economic efficiency of the use of Bioseven consists of: a reduction in the morbidity of animals, an increase in their preservation, an average daily increase in body weight, and therefore an additional increase of 0.300-1.200 kg (depending on the dose), a reduction in the cost of obtaining a unit of production (by 0.5 %) and a decrease in the cost of livestock products per head during the period of the experiment by 5.0–15.0 UAH. Thus, the hygienic evaluation of the effect of the probiotic Bioseven on the natural resistance of the rabbit's body indicates the absence of a suppressive effect of the drug on the metabolic processes of the body of laboratory animals. Key words: rabbit breeding, suppressive effect, probiotic, toxicological characteristics, biochemical, ecologically harmless, complete, food products, of animal origin, food safety, consumer.

Comparative analysis of the quality of beef obtained from crossbred steers of beef breeds for the livestock industry development

The scientific article presents the results of the scientific experiment on the study of qualitative indicators of beef obtained from crossbreeding of beef cattle breeds in the conditions of Volgograd agricultural enterprise JSC “Berdievsky elevator”. Obtained crossbred steers at the age of 9 months were divided into 4 groups: I experimental - ½ of a cross (Hereford х Russian Komolaya), II experimental - ½ of a cross (Kazakh Whitehead х Kalmykian), III experimental - ½ of a cross (Kalmykian x Aberdin-Angusian) and IV experimental - ½ of a cross (Aberdin-Angusian x Simmentalian). Formed groups of animals were put on fattening until 16 months of age. Growth dynamics of steers, morphological composition of blood and carcasses, qualitative characteristics of beef were evaluated.

Дослідження впливу ізольованої та комбінованої дії хлороформу i сульфату алюмінію з питною водою на структурно-функціональний стан крові тварин 44

Objective: study of the effect of chloroform and aluminum sulfate on hematological indicators of experimental animals. Materials and methods: combined effect of chloroform and aluminum sulfate on hematological indicators. Results: Evaluating the results of research under the conditions of the combined effect of chloroform and aluminum sulfate, it can be stated that the most pronounced changes are observed in groups of animals with the maximum level of load - 3 and 5 MPC, under the conditions of the isolated effect of chloroform and aluminum sulfate, and under the conditions of their combined effect. The detected changes indicate the influence of active factors on the cooperative nature of oxygen binding by hemoglobin, which affects the provision of the transport function of the protein and, accordingly, on the protective function of the group of leukocytes.Changes in the leukogram reflect the phases of the development of protective and adaptive processes in the immune-competent blood system and may indicate the formation of adaptive and adaptive reactions aimed at maintaining the stability of the body’s homeostasis with their subsequent disruption and exhaustion of compensatory mechanisms. Conclusions.The specified changes in the morphological composition of blood can be signs of: violations of physiological processes occurring in the body, slowing down of redox reactions, hypoxic manifestations, reduction and weakening of the immune response and reactivity, which cannot but be reflected in the vital activity and life expectancy of experimental animals.The extrapolation of these results to humans allows us to assume that the population’s constant consumption of drinking water with an excessive content of chloroform and aluminum sulfate over time can lead to changes in the blood system, weakening of the body’s protective immune function and creating conditions for the development of non-infectious pathology.

Study of morphological and biochemical blood composition in rats on the background of quercetin loading

The interaction of warm-blooded organisms with the environment is always reflected in the homeostatic equilibrium of metabolic processes. The dynamics of redox processes occurring in the body is primarily reflected in hematological indices. The aim of the investigation was to study reactive changes of morphological and biochemical blood composition in rats against the background of quercetin load. Objectives: to analyze the dynamics of morphological and biochemical composition of animal blood at the background of intragastric loading with quercetin in the form of oil solution during 30 days. The study was performed on 80 white mongrel male rats weighing 190-210 g, which were divided equally into control (intact) and experimental groups. The study of reactive changes in the morphological and biochemical composition of the blood of rats under the influence of quercetin was conducted in the dynamics before the experiment, as well as on 1, 3, 5, 7, 10, 15, 20, 25 and 30 days of experiment. It was found that against the background of additional loading with oil solution of quercetin in rats there were reactive changes in the morphological composition of the blood, which are reflected in the increased number of red blood cells, concentration of hemoglobin and leucocytes within the physiological norm, as well as changes in the biochemical composition of the blood, expressed in increased concentration of albumin and decreased concentration of albumin fractions in the rats of the experimental group compared with intact animals.

Evaluation of intraperitoneal administration of glucose solution using in the treatment of ketosis in dairy cows

Ketosis in high‐yielding dairy cows is the most common metabolic pathology during late dryness and early lactation. This work aims to establish the possibility and effectiveness of therapy for ketosis in dairy cows through the intraperitoneal injection of a 20% glucose solution. For the experiment, on days 21‐30 of lactation, two groups of black‐and‐white cows with a β‐hydroxybutyrate level above 1.0 mmol / l were formed. Animals of the first group (n = 10) were injected four times with an interval of 24 hours intraperitoneally with 1000 ml of 20% dextrose solution. Cows of the second group (n = 10) in a similar regimen were injected dextrose intravenously. Blood for research was obtained before the start of injections, after 5, 30 minutes, 1, 2, 3 hours after the first injection of the solution, and one day and seven days after the end of therapy. It was found that a single intravenous injection of dextrose during the first 5 minutes is accompanied by an increase in the concentration of the monosaccharide in the blood by 2.2 times (from 5.1 to 11.4 mmol / L; P <0.001). The level decreases to the initial values within 1 hour, and intraperitoneal infusion does not cause hyperglycemia. A redistribution of protein fractions accompanies therapy of cows with ketosis: a decrease in the albumin‐globulin coefficient by 16.8% (P <0.05) with intraperitoneal administration and by 26.9% (P <0.01) with intravenous administration. The activity of AST after intracavitary injections of dextrose decreased by 36.5% (P <0.05). The loading of erythrocytes with substances of low and medium molecular weight was 19.4% (P <0.05) with the intraperitoneal injection. It was not observed with the intravascular route of administration. The morphological composition of blood after intravenous administration of dextrose was characterized by an increase in the level of leukocytes by 34.8% (P <0.05), a decrease in erythrocytes by 11.9% (P <0.05), hemoglobin by 11.6% (P <0, 05), hematocrit by 12.3% (P <0.05). Therapy via intraperitoneal injection did not cause pronounced changes in these parameters. The intravenous administration of glucose promoted a more rapid elimination of ketone bodies, which decreased by 2 times one day after the end of therapy (P <0.05), but after 7 days, their level began to increase again (by 21.1%). It did not have significant differences with indicators at the time of diagnosis. Intraperitoneal infusions were accompanied by a slight decrease (by 16.3%) in the level of β‐hydroxybutyrate one day after the end of therapy, followed by a pronounced decrease in the concentration of ketones by day 7 (2.3 times; P <0.01). The dynamics of fructosamine indicate that intracavitary injections do not cause glycosylation of plasma proteins, while intravenous infusions increase the values by 37.0 ‐ 39.4% (P <0.001). Thus, intraperitoneal administration of glucose during ketosis in dairy cows has a more favorable effect on the morphobiochemical composition of the blood and provides a more prolonged therapeutic effect.

Effects of gonadectomy on clinical-hematological, metabolic and hormone conditions of cockerels

Gonadectomy (caponization) of cockerels is an important way of increasing their productivity, improving the quality and taste properties of the meat, and obtaining dietary products. The objective of the study was the influence of gonadectomy of cockerels on their clinical condition, morphological composition of blood, hemoglobin content and anabolism in the tissues, their productivity and chemical content of the muscles. In the experiment, we used 30 Adler silver cockerels aged 4 weeks, which were divided into two groups: control (intact) and experimental (gonadectomized) according to the analogue principle, with 15 individuals in each. The experiment lasted for 185 days, including the main period of 175 days. We determined that the body temperature of cockerels after gonadectomy increased as early as days one and three. In the blood of gonadectomized cockerels, the number of leukocytes decreased by 36.3%, thrombocytes – by 24.7%, while hemoglobin concentration, numbers of heterophils, eosinophils, basophils, monocytes and lymphocytes did not change compared with the intact individuals. On days 20 and 185 of the experiment, the concentration of testosterone in the blood plasma of gonadectomized cockerels was lower respectively by 57.1% and 53.1%, whereas no differences were found prior to gonadectomy and on the third day of the experiment. We determined increase in uric acid concentration and decrease in the level of ionizing calcium in blood plasma of gonadectomized cockerels compared with intact individuals, while the content of cortisol, glucose, total protein, triglycerides, cholesterol, total calcium and inorganic phosphorus, and also activities of alkaline phosphatase, alanine aminotransferase and aspartate aminotransferase did not change. Live weight of gonadectomized cockerels in the period from 45 to 105 days of the raising did not change, and was higher by 10.4–17.0% from day 115 to 145, and further remained not different from the control. Thoracic muscles of gonadectomized cockerels contained 1.8 times more fat, while the levels of moisture, dry matter, protein and ash in thoracic and thigh muscles did not change. The conducted studies have revealed the effect of gonadectomy of roosters on clinical-hematological parameters, metabolic processes, productivity of birds and chemical composition of muscles and may be used to improve the production of chicken meat with high dietary and taste properties.

ВЛИЯНИЕ ПРЕПАРАТОВ «ИМУНОФАН» И «ФОСПРЕНИЛ» НА МОРФОЛОГИЧЕСКИЙ СОСТАВ КРОВИ ТЕЛЯТ

The aim of the work was to study the effect of immunomodulators "Imunofan" and "Fosprenil" on the intensity of nitric oxide (II) formation and the morphological composition of blood in calves. Increased levels of stable nitric oxide (II) metabolites in the blood plasma of calves after the use of immunomodulators indicates the participation of NO in nonspecific immunity reactions. Also the established relationship between the level of stable nitric oxide (II) metabolites and the number of stab neutrophils proves that NO is one of the regulators of neutrophil activity.

Problems of blood leukemoid reactions in farm animals and birds

The problem of the formation of leukemoid reactions in cattle is considered. It is noted that such changes in the morphological composition of blood are most often characterized by a decrease in the quantitative content of lymphocytes while increasing the concentration of microphages (neutrophils). With the elimination of the cause that caused the manifestation of the leukemoid reaction of the blood, the morphological composition of the peripheral blood is restored to normal.

Changes in morphological composition of blood in rats under intragastric load with walnut meal

The basis for the existence of all living organisms is homeostasis. Any living organism is an open dynamic self-regulating system and self-regulation is based on the feedback principle. The use of biologically active substances, for example, plant meal, opens up great possibilities for modulation of physiological processes in the body. Walnut fruit meal also has a rich composition, contains almost all microelements, large amounts of protein as well as carotene, quinones, lecithin, water-soluble vitamins and flavonoids. The aim of the work was to study the adaptive changes in the morphological composition of rat blood to intragastric loading with walnut meal in the form of suspension on distilled water. The experiment was carried out on 60 white laboratory rats. Conclusion: intragastric loading with distilled water suspension of walnut meal in a concentration of 15 mg/100 g body weight of clinically healthy rats was accompanied by an increase in erythrocyte count, hemoglobin concentration and leukocyte count by 6.8%, 7.0% and 9.6%, respectively, compared with the control group animals.

ГЕМАТОЛОГИЧЕСКИЙ СПЕКТР И РЕЗИСТЕНТНОСТЬ МОЛОДНЯКА ОВЕЦ МЯСО-ШЕРСТНЫХ ПОРОД В ОНТОГЕНЕЗЕ

The paper presents materials characterizing the adaptive properties and natural resistance of young sheep of the Kuban factory type of the Lincoln and southern meat breeds, based on the study of the morphological composition of blood and indicators of mmunobiological resistance.

ПОКАЗАТЕЛИ КРОВИ БЫЧКОВ КАЛМЫЦКОЙ ПОРОДЫ НА ОТКОРМЕ ПРИ ВКЛЮЧЕНИИ В ИХ РАЦИОН МЕСТНЫХ ПРИРОДНЫХ КОРМОВЫХ ДОБАВОК В УСЛОВИЯХ ЦЕНТРАЛЬНОЙ ЯКУТИИ

Obtaining high results in the production of highquality beef in beef cattle breeding is impossible without well-organized fattening of gobies. In the conditions of Yakutia, fattening of gobies from 15 months of age can be carried out in autumn, after the summer grazing feeding. Under economic conditions of feeding, high growth rates of fattening young animals cannot be obtained. Therefore, intensive fattening with the use of mineral feeding of cattle is used. The paper presents research materials on the morphological and biochemical composition of blood and its serum in calves of the Kalmyk breed, which are on scientific and industrial fattening. In the experimental group of animals, local natural feed additives – zeolite and salt – were added to the diet, which served as adaptogens and sources of mineral elements. During the feeding period before the slaughter, the morphological composition of blood in terms of indicators has insignificant decreases, but within the physiological norm. We see these changes in the gobies of the experimental control group and associate them with a sharp decrease in atmospheric air temperature to –15 °C in the first ten days of November 2019 and a constant transition to roughage. It is also possible that the use of natural feed additives in the form of feeding zeolite and salt increases metabolic processes in the animal's body. A comparative analysis of biochemical parameters in the blood serum of gobies of the experimental group confirmed significant differences in hepatic enzymes (ALT and AST) in animals. The use of non-traditional natural feed additives with the inclusion in the diet of fattening gobies affects the hematological and biochemical parameters of blood and its serum, and, accordingly, meat quality.

MORPHOLOGICAL CHARACTERISTICS OF PERIPHERAL BLOOD OF COWS INFECTED WITH BLV AND THE FREQUENCY OF REGISTRATION OF LEUKEMOID REACTIONS IN COWS WITH LEUKEMIA-AFFECTED HERDS

In controlled experiments during planned studies of cattle for leukemia, animals that showed leukemoid changes in blood – quantitative redistribution of granulocytes and agranulocytes-were identified. Individual analysis revealed that granulocytosis was detected in animals with inflammatory processes. In addition, the article presents comparative indicators of serum proteins in cows at the hematological stage of the leukemic process, with the manifestation of leukemoid reactions and in clinically healthy cows. Characteristic changes in the synthesis of immunoglobulins in cows with leukemia and leukemoid changes in the morphological composition of blood were established. With successful treatment of inflammatory processes, the hematological status of cows is restored to the initial indicators.

Inesa Benedictovna Kozlovskaya: expert on motor control and space medicine

Inesa Benedictovna Kozlovskaya was born in Harbin in China. Her father, Benedict (Benecian) Kozlovsky, administered the Soviet consulate. In 1938 the family moved to Moscow and in 1945 Kozlovskaya became...

ОЦЕНКА ВЛИЯНИЯ ПРЕПАРАТОВ «КАРОФЕРТИН» И «ГЕМОБАЛАНС» НА ГЕМАТОЛОГИЧЕСКИЙ СТАТУС ДОНОРОВ И РЕЦИПИЕНТОВ ЭМБРИОНОВ

These studies reflect the results of the effectiveness of the use of drugs "Karofertin" and "Hemobalance" in prepar-ing cows for embryo transplantation. Studies on cows used the Holstein breed. At the same time, three experimental groups were formed, through which the drugs "Karofertin" and "Hemobalance" are admin-istered both as mono therapy and in combi-nation. The formulations were not adminis-tered to the control group. The aim was to evaluate these drugs for studies of the hema-tological status of animals that are used as donors and recipients of embryos, as one of the main criteria presented for embryo trans-plantation - this is their physiological status, especially from the reproductive system, as well as from other organs and systems. ... In this regard, the task was set - to assess the dynamics of the morphological composition of blood and leukogram in experimental animals. The study will also use the biochem-ical parameters of serum in cows when using "Carofertin" and "Hemobalance", and the concen-tration of gonadal hormones in the administration of these drugs. Thus, the studied drugs were ad-ministered by stabilizing the state of animals, in particular from the reproductive system, and the dynamics of their hematological status was as-sessed. Carofertin contains synthetic beta caro-tene, which is a provitamin A, participates in many processes in the body and is directly involved in the metabolism of steroid hor-mones, folliculogenesis, the formation of the corpus luteum, etc. Hemobalance is a multi-vitamin complex preparation containing ami-no acids, due to which optimizes metabolic processes in the body (protein, vitamin and mineral). During the experiment, a positive effect on the preparations and systems of experi-mental animals was found, but the best result was achieved with the combined administra-tion of "Carofertin" and "Hemobalance", during the experiment, a significant increase in hemoglobin by 27.2% was noted, an in-crease in the erythrocyte sedimentation rate by 1, 8 times and other indicators.

Mineral composition of the organism tissues and honeycombs of melliferous bees under the conditions of feeding them soybean flour and citrates of Cobalt and Nickel

The inadequacy of mineral nutrition leads to inhibition of physiological and metabolic reactions in the body of honeybees. It is known that Cobalt chloride is used to activate oviposition of the queen bee. It was established that Cobalt and Nickel citrate, obtained by the method of nanotechnology, corrects the mineral metabolism and affects the metabolism of bees. It is known that Cobalt plays an important role in the work of enzymes; synthesis of vitamin B12, promotes assimilation of vitamins A, E, C; increases protein metabolism, participates in hematopoiesis. Nickel also has a pronounced effect on hemopoiesis, namely on the morphological composition of blood. But its effect on the cell and subcellular level is not well understood. The results of studies of the effect of soybean flour with the addition of Cobalt and Nickel citrates on the content of mineral elements in the tissues of the body of bees and honeycombs are given. The research was carried out in the farms in the Lviv region, in April-May at the bees of the Carpathian breed. It was established that the content of Ferrum, Cuprum and Germanium in the tissues of bees increases with the addition of soybean flour with Сobalt citrate at a dose of 2 mg per 500 g of soy flour. When Nickel citrate was added to the feed at a dose of 1 mg per 500 g of soy flour, the content of Ferrum and Cuprum increased in honeycombs. The complex combination of Citrits Co and Ni, soy flour with sugar syrup was characterized by a decrease in the level of Zn in the tissues of the bees compared to its contents in the control group samples. In samples of biological material, the content of Сobalt, Nickel and the essential elements Cuprum, Zink, Ferrum, Selenium, Germanium was determined by atomic emission spectrometry with inductively coupled plasma. Citrates of the microelements were produced by the method of M. Kosinov and V. Kaplunenkо.

Changes of hematological parameters of in blood in cats ill with microsporium

There has been a massive tendency for cats to be kept as pets in Ukraine in recent years. The frequency of their diseases has also increased at the same time. Cats most often come into the homes of people from the street, from volunteers, rarely from nurseries. Due to this, Doctors often receive cats ill for microsporia, which is caused by fungi of the genus Microsporum and is one of the most common anthropozoonous diseases. The treatment process is carried out by a complex method. Analysis of the recommendations of various authors on the treatment of microsporia indicates the lack of immunostimulants in the conduct of a complex of therapeutic and preventive measures. Hematological studies were performed in order to find out the immune reactivity of the cats' organism during microsporia. The research was conducted on clinically healthy and cats ill for microspores. The obtained results of research showed that in cats with microsporia changes in morphological composition of blood were characterized by signs of anemia, leukopenia and lymphocytopenia. Changes in the structure of neutrophils were found in the type of vacuum and toxigenic grains in cats ill for microsporia. The toxic grains of neutrophils occur inside the cell as a result of physicochemical changes in the protein structure of the cytoplasm. Such cells can not provide phagocytosis of foreign agents and thus reduce the immune activity of the organism in cats ill for microsporium. A marked change in the shape of erythrocytes, which is characteristic of anemia, that is, erythrocytes-octantocytes with corneas by Jolly inclusions. Jolly's bodies are the remnants of the nucleus that have survived in erythrocytes because of the broken destruction of the normoblast nucleus. The obtained results indicate that the course and manifestation of microsporia in cats affects the immune status of the organism.

ГЕМАТОЛОГИЧЕСКИЕ ПОКАЗАТЕЛИ КОРОВ ПРИ ИСПОЛЬЗОВАНИИ ИММУНОМОДУЛИРУЮЩИХ ПРЕПАРАТОВ

The aim of the study is to increase the morphological and functional status of cows depending on their physiologi-cal state. The morphological composition of blood is one of the main informative systems and has long attracted the attention of researchers. Blood, as a co-single tissue, has been studied well enough. Its indicators are the main fac-tors in determining the state of an animal health, as well as pointing out the presence of pathological processes in inside the organism. To determine the effect of complex use of STEMB (embryonic stimulator) and Uteromastin on the blood parameters of cows in comparison with individual administration three groups of pregnant cows 
 (7.0-8.0 months) were formed separately, each with 20 heads in compliance with the method of groups-analogues (experimental-1, experimental-2, experimental-3). Animals in groups to be examined were provided the same con-ditions both in feeding and keeping. Animals of the first experimental group 25-30 days before calving were admin-istered STEMB drug hypodermic in the neck at a dose of 0.075 ml per 1 kg of live weight with an interval of 7 days three times, animals of the second experimental group were administered the drug Uteromastin 8-10 hours after calving intrauterine at a dose of 150 ml once. Cows of the third experimental group were administered drugs STEMB and Uteromastin in these doses (mixed). The influence of the complex use of drugs STEMB and Utero-mastin on morphological, biochemical and immunobiological parameters of blood of cows were studied on the 15th day after calving. The use of the drugs STEMB and Pteromalid complex improves cellular composition of the blood and indices of the blood serum, which enhances immunotoxicol system of organism of cows.

Morphological composition of blood and indexes of protein metabolism in dry cows

The results of a hematological study of cow’s blood are presented, as well as the results of an evaluation of the protein metabolism of serum of dry and newborn cows. The use of various vitamin-mineral premixes (P60-3/2 and P 60-3/P) in combination with and without propylene glycol has been analyzed in animal diets. This research was supported by FASO Russia project АААА-А18-118031390148-1. The methods of morphological investigation of blood, methods of biochemical study of protein metabolism parameters of blood serum, mathematical and statistical methods were used in the work. Studies have established that the use of various feed products in the rations of feeding animals and the various terms of their application have an effect on the morphological and biochemical composition of blood and serum, respectively. Changes are established two weeks before calving and on the third day after calving. The use of the premix P60-3/P in the feeding of animals of the third group throughout the entire dry period in combination with propylene glycol is accompanied by the most pronounced significant increase in erythrocyte content in these individuals on day 3 after calving (by 21.3%, P<0.05 ). Two weeks before calving, the content of serum of total protein (25.2-30.1%, <0.01) and albumins (21.7% (P<0.05) - 52.2% (P<0.01) The use of the third group of premix P60-3/P in the feeding of animals from the first day of the dry period is accompanied by the most pronounced significant increase in the total protein content of these individuals two weeks before calving (30.1% %, P<0.01).