Morphological Studies Research Articles

Клинические и гистологические особенности быстропрогрессирующего гломерулонефрита у детей

Rapidly progressive glomerulonephritis (RPGN) associated with antineutrophil cytoplasmic antibodies (ANCA) is complicated in children due to the severity of the disease and the lack of clear consensus on treatment. The purpose of this research was to analyze the course of RPGN and its outcomes in children depending on the morphological basis after the results of nephrobiopsy. Materials and methods used: a single-center cohort retrospective study had been carried out as medical records’ analysis of patients diagnosed with RPGN aged 1 to 18 y/o who were observed at the Nephrology Department of the Scientific Research Institute of Pediatric Nephrology and Urology with the National Medical Research Center for Children’s Health (Moscow, Russia) in 2015-2024. Renal survival was assessed for different clinical and morphological options, the Renal Risk Score was assessed then. Results: 18 (7 m/11 f) were identified of Me age of diagnosis 14.1 [9.9; 15.5] y/o. ANCA was detected in all patients: pANCA in 12 (66.7%, 95% CI 40.9-86.7) and cANCA in 6 (33.3%, 95% CI 13.3-59.0) plus a single patient had a rare combination of dual positivity for anti-GBM and MPO-ANCA. Extrarenal manifestations were described in 10 (55.6%, 95% CI 30.8-78.5). Morphological subclassification of focal segmental glomerulosclerosis was detected in 5 (31.3%, 95% CI 11-58.7), extracapillary proliferation in 8 (50%, 95% CI 24.7-75.4), sclerosing in a single patient (6.3%, 95% CI 0.2-30.2) and the mixed one in 2 cases (12.5%, 95% CI 1.6-38.4). The median follow-up period was 21.6 [12.6-35.3] months, the outcome of stage 5 chronic kidney disease (CKD) was observed in 4, overall renal survival after 12 months was 94.4% (95% CI 84.4-100.0) and 86.6% (95% CI 70.6-100.0) after 36 months. An increase in the relative risk of achieving stage 5 CKD in patients with extrarenal (general) manifestations was detected as 1.67 times (95% CI 1.01-2.77) and 10.5 times (95% CI 1.46-75.42) in those receiving dialysis. Differences in the median glomerular filtration rate at onset were revealed in patients with extrarenal manifestations and isolated glomerulonephritis (p=0.004). Conclusion: when choosing treatment tactics for RPGN in children and assessing renal prognosis, it is necessary to take into consideration the results of a morphological study and the degree of damage to the renal tissue.

Bioinspired copper oxide nanocomposites: harnessing plant extracts for enhanced photocatalytic performance.

This study focuses on developing copper oxide-based nanocomposites using plant extracts for photocatalytic applications. Curcuma amada leaf and Alysicarpus vaginalis leaf extracts were utilized alongside recycled copper precursors to synthesize photocatalysts via a green synthesis approach. Structural characterization through X-ray diffraction confirmed the formation of monoclinic CuO with reduced crystallite sizes due to plant extract incorporation. Fourier-transform infrared spectroscopy identified additional functional groups from the plant extracts, enhancing the material's properties. UV-Vis spectroscopy demonstrated increased light absorption and narrowed bandgaps in the nanocomposites, crucial for efficient photocatalysis under visible light. Morphological studies using FESEM revealed unique leaf-like structures in nanocomposites, indicative of the plant extract's influence on morphology. Photocatalytic degradation of methylene blue, rhodamine B, Congo red, and reactive blue 171 dyes showed enhanced performance of plant extract-modified CuO compared to without plant extract mediated CuO, attributed to improved charge carrier separation and extended lifetime. The effects of pH, catalyst dosage, and dye concentration on degradation efficiency were systematically investigated, highlighting optimal conditions for each dye type. Radical scavenger studies confirmed the roles of holes and hydroxyl radicals in the degradation process. Kinetic analysis revealed pseudo-second-order kinetics for dye degradation, underscoring the effectiveness of the nanocomposites. Overall, this research provides insights into sustainable photocatalytic materials using plant extracts and recycled copper, showcasing their potential for environmental remediation applications.

Chemical treatment, fibre length, and fibre loading affecting the mechanical and morphological characteristics of flax fibre/polylactic acid (PLA) green composites developed by injection moulding

AbstractThis paper presents the parametric investigation and optimization of various chemical treatment parameters that affect the mechanical performance of the green composite. The injection moulding method was used to produce the green composites using flax fibre (FF) and polylactic acid (PLA). The chemical parameters chosen to investigate their effects are chemical type (sodium hydroxide, sodium carbonate, and potassium hydroxide), chemical concentrations (1 %, 2 %, and 3 % (w/v)), and duration for fibre treatment (2 h, 4 h, and 6 h). The mechanical performance of the green composites was assessed by evaluating the various properties namely strength, modulus, and elongation under tensile, share, flexural, and compression loading conditions. The morphological study was also performed to examine the failure behavior of the composite after mechanical testing. The effect of fibre length (2 mm, 3 mm, 4 mm, 5 mm, and 6 mm) and fibre loading (10 wt.%, 20 wt.%, and 30 wt.%) on the performance of the flax fibre (FF)/polylactic acid (PLA) composite was also investigated. The fibre dispersion, fibre orientation, and fibre length retention were investigated to assess the characteristics of fibre during injection moulding of the developed flax fibre (FF)/polylactic acid (PLA) composite.

Supramolecular J- and H-aggregation of Napthalimide-conjugated Dipeptide in Mixed-solvent Systems and Its Application in Cell Imaging.

In this work, a core substituted NMI-conjugated dipeptide (4MNLV) was extensively studied in mixed solvent systems to explore the polarity effect on the self-assembly pattern and their photophysical property. 4MNLV adopted a J- or H- type aggregation pattern depending upon the polarity index of the solvent system chosen. The self-assembly process was achieved through the anti-solvent effect. UV-vis study suggested that if the stock solution of 4MNLV was diluted with a relatively more polar solvent (compared to the stock solvent), then the system acquired J- type of aggregation pattern by showing a red-shift in their absorption maxima (λmax). Conversely, when the stock was diluted by a relatively less polar solvent, H-type of aggregation was observed where blue shift of λmax was noticed. The emission spectra and the lifetime of the self-assembled materials were also influenced by the chosen solvent system. The chirotopic behaviour of these self-assembled materials was studied through CD spectroscopy. Morphological study indicated the formation of helical nanofibrillar structures. The bright green fluorescence of these highly biocompatible naphthalimide-peptide conjugate was used for cell imaging application, indicating its futuristic scope.

A comparative analysis of crustacean exoskeletons: structural, microstructural, morphological, and UV absorption studies

Abstract This study aims to investigate the structural, thermal, and spectral characteristics along with ultra-violet (UV) absorption of various marine benthos exoskeletons, such as various species of crabs (Portunus sanguinolentus, Portunus pelagicus, Charybdis feriata) and mantis shrimp (Oratosquilla oratoria). Their unique properties and ability to survive in harsh oceanic environments make them interesting research subjects. This research utilized powder X-ray diffraction (XRD) analysis to determine the crystal structure of the benthic varieties. The sample surface was analysed using high-resolution micrographs obtained from field-emission scanning electron microscopy (FESEM) identified the presence of chitin and calcite in the marine benthos, which was further confirmed by differential scanning calorimetry (DSC), and Fourier transform infrared spectroscopy (FTIR). The optical characteristics were investigated using UV-visible spectroscopy. The proximate analysis revealed high protein content in the mantis shrimp exoskeleton compared to other crab species, revealing its excellent UV-absorption characteristics. Overall, this research has the potential to broaden our understanding of marine organisms, which can have potential applications in biotechnology and materials science to develop nature-inspired innovative materials sustainably.

Fuchs endothelial corneal dystrophy: aspects of pathogenesis

Fuchs endothelial corneal dystrophy (FECD) – multigenic bilateral disorder, characterized by dysfunction of corneal endothelium cells (CECs) that eventually results in loss of transparency. Purpose: To evaluate the pathogenesis of FECD with histological and immunohistochemical methods, immunofluorescence, scanning electron microscopy (SEM). Methods: Endothelium–Descemet membrane (EDM) complexes, corneal buttons were obtained from 76 patients (85 eyes) with FECD during keratoplasty and divided into 1A, 2A, 3A groups, 15 EDMs (donor tisuue) – 1B, 2B, 3B groups (control). Morphological (hematoxylin/eosin staining) and immunohistochemical (primary antibodies to cytokeratin AE1/AE3 and vimentin) studies (1A, 1B groups), phase-contrast microscopy and immunofluorescence analysis of tight junction protein ZO-1 (2A, 2B groups), SEM (3A, 3B groups) were performed. Results: FECD is characterized by decline of CECs, cell and nuclear enlargement. Nuclear-cytoplasmic ratio of CECs is relative to control. CECs expression ZO-1 is decreased in the area of guttae ingrowth. Coexpression of cytokeratin AE1/AE3 and vimentin is found. Morphological and immunohistochemical studies show DM’ thickening, stromal and epithelial edema and local fibrosis, vimentin (stromal cells) and cytokeratin AE1/AE3 (epithelium) expression in FECD. Conclusion: Pathogenesis of FECD include CECs’ epithelial-mesenchymal transition, followed by guttae formation – the excrescences, which destroy cytosketon and lead to progressive loss of CECs. Changes in permeability of endothelium cause edema and fibrosis of stroma and epithelial layer.

Green Electrospinning of Highly Concentrated Polyurethane Suspensions in Water: From the Rheology to the Fiber Morphology

AbstractSuspension electrospinning allows the environmental‐friendly fabrication of nano‐micro‐fibrous membranes since it is based on the processing of an aqueous particle suspension in which a hydrosoluble template polymer is added to insure the formation of a continuous fiber. Here, the case of polyurethane (PU) aqueous suspensions formulated with poly(ethylene oxide) (PEO) as the template polymer is studied. The effect of several parameters (particle size, PU/PEO ratio, PEO molar mass, and PEO concentration in the continuous phase) on particle‐particle and particle‐template polymer interactions that influence the rheological properties of the formulation and finally the electrospinning and the fiber morphology, is studied. The goal is to process a formulation with the highest particle content as possible. Thanks to a deep rheological investigation and the study of interactions and suspension morphology by zeta potential and diffusing wave spectroscopy, it is shown that regular fibers are efficiently produced when small particles are electrospun under favorable particle‐template polymer interactions and without screening the electrostatic repulsion between particles. Finally, a fibrous membrane is obtained from a formulation with a PU/PEO weight ratio equal to 50 under very stable and efficient production conditions.

Nano-oxides of metal particles imbedded polyethersulfone films: morphology, structural and mechanical studies

Nano-oxides of metal particles imbedded polyethersulfone films: morphology, structural and mechanical studies

Morphofunctional characteristics of the liver after administration of ascorbic acid in a model of radiation hepatitis

Introduction: Radiation-induced hepatitis develops both with direct irradiation of malignant neoplasms of the liver and abdominal organs. An important task of modern radiobiology is the development of methods for the prevention of acute and chronic post-radiation complications, for example, the injections of protectors. Materials and methods: Wistar rats (n = 40) were divided into groups: I – control (n = 10); II (n = 10) – electron irradiation; III (n = 10) – injection of ascorbic acid before electron irradiation; IV (n = 10) – injection of ascorbic acid. A biochemical blood test, oxidative status analysis, morphological, morphometric and statistical studies were carried out. Results: In group III, a less pronounced change in the main morphological and morphometric parameters was noted compared to group II; indicators of biochemical analysis and oxidative status approached control values. Conclusions: According to the results of the study, it was revealed that local irradiation with electrons after a week leads to disruption of the histoarchitecture of the liver, and the injection of ascorbic acid reduces the depth and range of radiation-induced hepatitis.

Phase engineered enhancement of photocatalytic and Opto-magnetic properties of CuO nanoparticles through fluorine and gadolinium doping

The present study comprises co-doping of CuO nanoparticles with gadolinium (Gd) and fluorine (F) using the sol-gel method to achieve phase stabilization and tune their physicochemical properties. X-ray diffraction (XRD) and X-ray photoelectron spectroscopy (XPS) analyses revealed successful incorporation of the dopants and the stabilization of the CuO phase with increasing Gd content. Morphological studies revealed grain refinement and an enhanced surface-to-volume ratio upon co-doping. Average particle size decreased from 194 nm to 138 nm for pure and 5%F to 126 nm, 101 nm, and 81 nm for, 1mol%, 2mol% and 3mol% Gd along with 5mol% F co-doped CuO nanoparticles. Increasing the Gd ratio also tuned the band structure and significantly improved the optical properties of the CuO nanoparticles. Additionally, a transition from weak ferromagnetic ordering to paramagnetic behavior is observed. Coercivity decreased to 2.5 Oe for Cu0.97Gd0.03F0.05O0.95 as opposed to 396.3 Oe for CuF0.05O0.95. Photocatalytic activity studies using rhodamine B (Rh B) as a model probe revealed a pronounced enhancement in degradation kinetics with increasing gadolinium (Gd) doping, culminating in around 2.9 times faster degradation rate for 3 % Gd-doped CuO nanoparticles compared to pure CuO nanoparticles. After 3 h of UV light irradiation, the photodegradation efficiency of Cu0.97Gd0.03F0.05O0.95 was 94 %, which is significantly higher than the 80 % and 69 % efficiency of CuF0.05O0.95 and CuO, respectively. These remarkable optical, magnetic, and photocatalytic properties of the co-doped nanoparticles offer promising candidacy for various applications, including photocatalysis, solar energy harvesting, magnetic switching, and magnetic sensing.

Clarification of the distribution, conchological diversity, and taxonomic status of the Iberian snail Iberus globulosus C.R. Boettger, 1913 (Gastropoda: Stylommatophora: Helicidae)

The taxonomic status of Iberus globulosus has been unsatisfactorily resolved since its original description, but in 2008 a molecular phylogenetic study of the genus Iberus suggested that it could be a valid species. However, limited information on both its geographic distribution and its conchological variability has made it difficult to properly delineate the species. Our exhaustive sampling throughout the potential area of its geographic distribution and the morphological study herein, together with pre-existing genetic evidence, allow us to confirm the validity of I. globulosus. Consequently, we improve the characterization of I. globulosus by redescribing it. Additionally, we provide information on the potential for hybridization among I. globulosus and geographically and phylogenetically close congeneric species.

Impact of the Three-Dimensional Arrangements of Polyhydroxylated Crosslinkers on the Resulting Properties of Chitosan-Based Hydrogels

Chitosan was subjected to a crosslinking reaction with three polyhydroxylated diacids (glucaric (GlcA), mannaric (ManA), and mucic (MucA) acids) that only differ in the spatial orientation of their hydroxyl groups. This work aimed to obtain experimental evidence of the impact of the three-dimensional arrangement of the crosslinkers on the resulting properties of the products. In all the cases, the products were hydrogels, and their chemical structures were fully elucidated by FT-IR spectroscopy and conductometric titration. Thermogravimetric and morphological studies were also carried out. The specific surface area of all the products was similar and higher than that of native chitosan. Moreover, all hydrogels were characterized in terms of viscoelastic properties and long-term stability under external perturbation. Furthermore, their lead adsorption efficiency and swelling capacity were assessed. Despite the resemblant chemical structure in all the hydrogels, Ch/ManA exhibited the highest lead adsorption capacity, (Ch/ManA: 93.8 mg g−1, Ch/GlcA: 82.9 mg g−1, Ch/MucA: 79.2 mg g−1), while Ch/GlcA exhibited a remarkably higher swelling capacity (i.e., ~30% more than Ch/MucA and ~40% more than Ch/ManA). The results obtained herein evidenced that the selection of the polyhydroxylated crosslinker with the appropriate three-dimensional structure could be crucial to finely adjust the final materials’ features.

Research on the historical spatial characteristics and conservation strategies of colonial cities in Asia and Africa: a case study of 21 typical cities

Colonial cities in Asia and Africa, developed under the dual influence of native and sovereign cultures during the colonial era, exhibit unique urban morphological characteristics and reflect the planning ideologies of diverse cultures. Thus, the morphological study of colonial cities in Asia and Africa is crucial for understanding and identifying the historical and cultural value of these cities, which in turn enables the formulation of precise conservation strategies. In light of this, the study develops an urban morphological analysis methodology comprising "Colonial Background Analysis—Morphological Characteristics Analysis—Driving Factor Extraction" based on the Conzenian Approach, which is used to examine the morphology of 21 typical colonial cities in Asia and Africa across various colonial periods. As a result, "Dual-City" emerges as the core spatial characteristic of colonial cities in Asia and Africa, reflecting the morphological differences in road layouts, urban fabric, and urban cores between native and European zones. Additionally, as native settlement sizes, social structures, and cultural identities differ between cities, three major spatial patterns of the "Dual-City" model can be identified: separated, mediated, and integrated spatial patterns, resulting from the varied planning approaches applied by colonizers. Furthermore, suggestions for the conservation of colonial heritage are proposed based on the driving factors analysis from the morphological study.

Variation in Phenology and Morphological Traits of Seed-Propagated Laggera alata and Laggera crispata Forms

The phenological and morphological variation studies among forms of Laggera Sch. Bip. Ex. Benth. and Hook species are limited, despite the medicinal use of the genus. Therefore, this study aimed to document phenology and morphological variation in cultivated populations of Laggera alata and Laggera crispata forms from seedling to maturity. The forms were categorized as Laggera alata with a small capitulum (LA-SC), Laggera alata with a large capitulum (LA-BC), Laggera crispata from South Africa (LC-SA), and Laggera crispata from Zimbabwe (LC-ZIM). Seeds were germinated in Petri dishes, transplanted to plug trays, and later to field plots at 60 days. Phenological events were recorded when observed in at least one plant. Twelve qualitative and four morphometric traits were measured monthly on five plants per Laggera form. Analysis of variance and Tukey’s Honestly Significant Difference test (p < 0.05) were used for data analysis. Results indicated significant variation in phenology, qualitative traits, leaf traits, plant height, and stem diameter both within and between L. crispata and L. alata forms. Morphometric traits, such as leaf size and the number of leaves per plant, were identified as key descriptors for differentiating L. alata forms. These findings provide a foundation for the introduction of Laggera forms into farming systems for medicinal and commercial purposes.

Understanding the Unique Corrosion Phenomenon of Sanxingdui Embrittled Gold Masks Using Scanning Electrochemical Cell Microscopy (SECCM): Intergranular Corrosion of Au-Ag-Pb Ternary Alloy

The study investigated the rare corrosion of embrittled gold masks excavated from the Sanxingdui archaeological site, attributing the embrittlement to preferential corrosion of intergranular Pb-containing phases through morphological studies using metallographic microscopy and SEM-EDS. Scanning electrochemical cell microscopy (SECCM) technology was used to quantitatively analyze simulated Au-Ag-Pb alloy samples to compare the electrochemical properties of different phases at the microscopic level. The results revealed an electrochemical activity order of Au-Ag < Au2Pb < AuPb2+PbxOy, which explains the varying levels of retention for different components in gold masks and provides a reference for subsequent conservation strategy.

Panmixia and local endemism: a revision of the Eubranchus rupium species complex with a description of new species.

Species of the genus Eubranchus Forbes, 1838 (Mollusca: Gastropoda: Nudibranchia) are common faunistic elements of boreal benthic ecosystems, associated with hydroid communities. Recent studies have suggested that the widely distributed trans-Arctic E. rupium (Møller, 1842) constitutes a complex of at least three candidate species, but the detailed taxonomy of the complex remains unresolved. The purpose of the present paper is to conduct an integrative taxonomic study including molecular genetic methods (a phylogenetic analysis using COI , 16S rRNA and histone H3 with application of species delimitation methods) and morphological study (light and scanning electron microscopy) of E. rupium and closely related species. The specific aims of this study were to establish the species boundaries, morphological variability, and the phylogeographic structure within this group. The phylogeographic analysis included a TCS -based network analysis, an analysis of molecular variance (AMOVA), divergence time estimations, and ancestral area reconstructions. We demonstrate that specimens initially identified as E. rupium included three distinctive species: the nominal E. rupium with an amphiboreal range, the new species Eubranchus novik sp. nov. from the Sea of Japan, for which a taxonomic description is provided in this paper, and Eubranchus sp. from the northern Kuril Islands, which requires the collection and study of additional material for formal description. Our results confirm the amphiboreal distribution of E. rupium , as no geographic structure was found across Pacific, Arctic and Atlantic populations, and the results of the AMOVA analysis showed no differences between groups of samples from different geographic regions. The divergence of the 'Eubrancus rupium species complex' is estimated from the late Miocene or the Miocene-Pliocene boundary to the late Pliocene. It is hypothesised that the most probable ancestral region for the Eubranchus rupium species complex is the north-western Pacific, and the subsequent speciation likely occurred due to dispersal followed by allopatric speciation. ZooBank: urn:lsid:zoobank.org:pub:228E0C46-0BF7-4DDD-9C00-67B50E298D65.

Synthesis and characterizations of silver nanoparticles-based conductive ink for high-frequency electronics

This work presents the synthesis and performance evaluation of silver nanoparticles (Ag NPs)-based ink for high-frequency applications. Through varying concentrations, ratios of precursors, and reducing agents, three inks having different NP sizes are made and transformed into patterns. Structural, optical, and morphological studies of as-prepared NP-based inks were carried out using different characterization tools. Finally, for feasibility verification, synthesized ink for printed electronics, a prototype fabrication of a micro-strip transmission line and inline patch antenna was made. The simulation was performed by CST Microwave Studio to optimize the parameters of the prototype antenna and transmission line. The optical microscope revealed smooth morphology of the antenna. The return loss of the fabricated transmission line and antenna analyzed by the Vector Network analyzer showed that the silver ink-based prototypes have good efficiency and low loss. Overall, the results highlight the remarkable performance of NPs towards printed radio frequency-based electronics.

Synthesis and Anti-proliferative, Tyrosine Kinases Inhibitions of New Xanthene Derivatives and their Morphological Studies

Synthesis and Anti-proliferative, Tyrosine Kinases Inhibitions of New Xanthene Derivatives and their Morphological Studies

Phleum pratense-pollen adaptive variations and pollen microbiome investigation under different climatic regions and prospects of allergenicity.

Phleum pratense is an allergenic grass that pollinates in spring in Pakistan. Databases Allergenonline.org and Allergen.org record ten P. pratense allergens and their isoforms. Phl P 1, Phlp 5, and Phl p 11 are major P. pratense-pollen allergens with demonstrated basophil activity and skin test reactivity. Little is known about P. pratense pollen adaptive variations in different climatic regions and pollen-associated microbial diversity. In this study, we collected P. pratense-pollen and soils in the spring season 2022. Samples were collected from three climatic regions in Pakistan (R1, R2 and R3) with differences in mean monthly air temperature, mean monthly precipitation and elevation. The morphology of pollen was observed by light microscopy, scanning electron microscopy (SEM), biochemical fingerprint analysis, and composition of pollen were investigated by fourier-transform infrared spectroscopy (FTIR). The pollen-associated bacterial populations were identified through a Biolog GEN III microplate system. The pollen water-soluble proteins were isolated and stabilized in phosphate buffer saline (PBS) and tested for allergenicity responses through dot blots and western blots analysis. The morphology study found difference in pollen biochemical composition. Biolog identified Brevibacterium epidermidis and Pantoea agglomerans from P. pratense pollen. Protein extract quantification and sodium dodecyl sulfate-poly acrylamide gel electrophoresis (SDS-PAGE) gel found decreased protein expression in R1 region pollen compared to R2 and R3 region pollen. Allergenicity studies found differential expression of beta-expansin and profilin allergens in pollen obtained from the three regions. Beta-expansin and profilin were suppressed in R1 pollen and expressed in compared to R2 and R3 pollen. This is the first study to identify B. epidermidis and P. agglomerans growth on P. pratense pollen. Variable allergen expression in P. pratense pollen has also been observed in different regions. Soil pH, an increase in mean monthly temperature and a decrease in mean monthly precipitation correlated with pollen biochemical composition, and reduced beta-expansin and profilin expression involved in pollen growth and development. The findings of this research are unique, which enhances basic knowledge and understanding of P. pratense-pollen associated microbiota and climate change impacts on the pollen allergen expression.

Influence of Ni-doping on CuCo2O4 electrode for enhanced supercapacitor performance and sustainable energy storage

This work provides a revolutionary strategy for creating high-performance supercapacitors by designing and fabricating a unique nanostructured bimetallic oxide electrode. The proposed electrode leveraged the synergistic effects of metal oxides to enhance both energy density and charge-discharge kinetics. Ni-doped CuCo2O4 nanostructures (Cu1-xNixCo2O4) were synthesized in incremental order (x = 0.0, 0.05, 0.10, and 0.15) by facile sol-gel auto-combustion route. The nanostructures analyzed through x-ray diffraction, FTIR spectroscopy, Micro-Raman spectroscopy, x-ray photoelectron spectroscopy (XPS) and Scanning electron microscopy revealed the single phase and polycrystalline nature of CuCo2O4, with some impurity phases of CuO. The surface morphology studies showed numerous pores among the grains of Cu1-xNixCo2O4. Cyclic voltammetry, galvanostatic charge-discharge, and electrochemical impedance spectroscopy (EIS) were used to investigate the electrochemical performance of synthesized Cu1-xNixCo2O4 samples. In a 3 M KOH electrolyte solution, the Cu1-xNixCo2O4 electrodes with x = 0.05 exhibited 2340 Fg−1 specific capacitance at 5 mVs−1, demonstrating superior electrochemical performance with excellent rate capability. Furthermore, it exhibited 35.88 Whkg−1 energy density, an exceptional 2484.74 Wkg−1 power density, and retained 99.9 % capacitance after 5000 cycles, demonstrating good stability. The results suggest that porous bimetallic oxide nanostructures can be promising candidates for the development of high-performance, environmentally friendly supercapacitors.