Mood In Individuals Research Articles

No evidence for any effect of multiple sessions of frontal transcranial direct stimulation on mood in healthy older adults

The dorsolateral prefrontal cortex (DLPFC) is part of a network important for emotional regulation and the possibility of modulating activity in this region with transcranial direct current stimulation (TDCS) to change mood has gained great interest, particularly for application in clinical populations. Whilst results in major depressive disorder have been promising, less is known about the effects of TDCS on mood in non-clinical populations. We hypothesized that multiple sessions of anodal TDCS applied over the left DLPFC would enhance mood, primarily as measured by the Profile of Mood States questionnaire, in healthy older adults. In addition, in an exploratory analysis, we examined the potentially moderating role of working memory training. Working memory, just like emotional regulation, taxes the DLPFC, which suggests that engaging in a working memory task whilst receiving TDCS may have a different effect on activity in this region and consequently mood. A total of 123 participants between 65 and 75 years of age were randomly assigned to receive either 20 sessions of TDCS, with or without working memory training, or 20 sessions sham stimulation, with or without working memory training. We found no support for enhancement of mood due to TDCS in healthy older adults, with or without cognitive training and conclude that the TDCS protocol used is unlikely to improve mood in non-depressed older individuals.

In defense of pluralist theory

In this article I defend pluralist theory against various objections. First, I argue that although traditional theories may also account for multiple ways to achieve social understanding, they still put some emphasis on one particular epistemic strategy (e.g., theory or simulation). Pluralist theory, in contrast, rejects the so-called ‘default assumption’ that there is any primary or default method in social understanding. Second, I illustrate that pluralist theory needs to be distinguished from integration theory. On one hand, integration theory faces the difficulty of trying to combine traditional theories of social understanding that have contradictory background assumptions. On the other hand, pluralist theory goes beyond integrating traditional theories by accounting for a variety of factors that may play a role in social understanding but have been (widely) neglected in such theories, including stereotype activation, social and personal relationships, contextual features, individual moods, perceptions, and so on. Third, I argue that if the default assumption is rejected, pluralist theorists need to provide another positive account of why particular cognitive processes are more likely to come into play in a specific instance of social understanding than others in order to provide a genuine alternative to traditional theories. I discuss three versions of pluralist theory that meet this challenge by pointing to normativity, fluency, and interaction.

Peripheral blood metabolome predicts mood change-related activity in mouse model of bipolar disorder

Bipolar disorder is a major mental illness characterized by severe swings in mood and activity levels which occur with variable amplitude and frequency. Attempts have been made to identify mood states and biological features associated with mood changes to compensate for current clinical diagnosis, which is mainly based on patients’ subjective reports. Here, we used infradian (a cycle > 24 h) cyclic locomotor activity in a mouse model useful for the study of bipolar disorder as a proxy for mood changes. We show that metabolome patterns in peripheral blood could retrospectively predict the locomotor activity levels. We longitudinally monitored locomotor activity in the home cage, and subsequently collected peripheral blood and performed metabolomic analyses. We then constructed cross-validated linear regression models based on blood metabolome patterns to predict locomotor activity levels of individual mice. Our analysis revealed a significant correlation between actual and predicted activity levels, indicative of successful predictions. Pathway analysis of metabolites used for successful predictions showed enrichment in mitochondria metabolism-related terms, such as “Warburg effect” and “citric acid cycle.” In addition, we found that peripheral blood metabolome patterns predicted expression levels of genes implicated in bipolar disorder in the hippocampus, a brain region responsible for mood regulation, suggesting that the brain–periphery axis is related to mood-change-associated behaviors. Our results may serve as a basis for predicting individual mood states through blood metabolomics in bipolar disorder and other mood disorders and may provide potential insight into systemic metabolic activity in relation to mood changes.

The Roth Project - Music and Memory: A Community Agency Initiated Individualized Music Intervention for People with Dementia

"The Roth Project - Music and Memory" is a music-based intervention program, implemented by the Alzheimer's Association of Central and Western Kansas, which provides a non-pharmacological means for addressing neuropsychiatric symptoms in individuals with dementia. Participants were individuals with dementia who were enrolled in The Roth Project - Music and Memory. Post-intervention surveys were distributed to caregivers of participants which assessed caregiver satisfaction with the program as well as caregiver perception of the impact of individualized music on mood and behavioral symptoms. Of returned surveys (n = 79), 99% of caregivers indicated they were satisfied or very satisfied with the program and 94% of caregivers perceived participants to like or very much like listening to the music. While a substantial number of participants required assistance with iPod use (95%), the majority of participants were observed to listen to the music with stable or increased frequency over time. Personalized music was observed to improve mood in 78% of cases, with the most frequent benefits being improved overall happiness, decreased anxiety, increased positive emotional expression, and decreased depression. The Roth Project - Music and Memory was well received by caregivers and was perceived to benefit mood of individuals with dementia. These results provided ongoing support for individualized music-based interventions and demonstrated that such interventions, when implemented by community agencies, can be well received by those who use them.

Occupational Therapy's Role in the Management of Non-Motor Symptoms in Parkinson's Disease

This review aimed to determine the efficacy of therapeutic interventions for the management of cognition, mood, and sleep impairments in individuals with PD. This systematic review guided program development at a local YMCA discussing PD and therapeutic non-pharmalogical interventions for cognition, mood, and sleep.

The impact of targeted cathodal transcranial direct current stimulation on reward circuitry and affect in Bipolar Disorder.

Bipolar Disorder is costly and debilitating, and many treatments have side effects. Transcranial Direct Current Stimulation (tDCS) is a well-tolerated neuromodulation technique that may be a useful treatment for Bipolar Disorder if targeted to neural regions implicated in the disorder. One potential region is the left ventrolateral prefrontal cortex (vlPFC), which shows abnormally elevated activity during reward expectancy in individuals with Bipolar Disorder. We used a counterbalanced repeated-measures design to assess the impact of cathodal (inhibitory) tDCS over the left vlPFC on reward circuitry activity, functional connectivity, and affect in adults with Bipolar Disorder, as a step toward developing novel interventions for individuals with the disorder. −1mA cathodal tDCS was administered over the left vlPFC versus a control region, left somatosensory cortex, concurrently with neuroimaging. Affect was assessed pre and post scan in remitted Bipolar Disorder(n=27) and age/gender-matched healthy (n=31) adults. Relative to cathodal tDCS over the left somatosensory cortex, cathodal tDCS over the left vlPFC lowered reward expectancy-related left ventral striatal activity (F(1,51)=9.61,p=.003), and was associated with lower negative affect post scan, controlling for pre-scan negative affect, (F(1,49)=5.57,p=.02) in all participants. Acute cathodal tDCS over the left vlPFC relative to the left somatosensory cortex reduces reward expectancy-related activity and negative affect post tDCS. Building on these findings, future studies can determine whether chronic cathodal tDCS over the left vlPFC has sustained effects on mood in individuals with Bipolar Disorder, to guide new treatment developments for the disorder. ISRCTN11314056

The effects of acute aerobic exercise on mood and inflammation in individuals with multiple sclerosis and incomplete spinal cord injury.

Spinal cord injury (SCI) and multiple sclerosis (MS) are associated with increased risks of depression. Acute exercise may improve mood in these populations via its affect on inflammation. To determine if acute exercise can positively affect mood in individuals with SCI and MS, and whether exercise-induced changes in inflammation contribute to such improvements. Thirteen participants completed 30 minutes of moderate-intensity exercise. Mood data (POMS questionnaire) and blood samples were taken before and after exercise, and blood was analyzed for inflammatory mediators and kynurenine pathway metabolites. There was a significant reduction in total mood disturbance (TMD) pre to post-exercise, and pre to one-hour post-exercise. There was a significant decrease in TNF-α from pre to post-exercise, with further reductions one-hour post-exercise. There were no correlations between changes in TMD and changes in inflammation. However, changes in certain cytokines showed significant or trending correlations with changes in subsets of the POMS. Likewise, there was a trend for a correlation between exercise-induced changes in KYN/TRP and depression (p = 0.096). Acute exercise can positively affect mood after SCI and MS, and this change may be partially accounted for by exercise-induced changes in inflammation. This relationship may be, in part, kynurenine pathway-dependent.

AppsPred: Predicting context-aware smartphone apps using random forest learning

Due to the popularity of context-awareness in the Internet of Things (IoT) and the recent advanced features in the most popular IoT device, i.e., smartphone, modeling and predicting personalized usage behavior based on relevant contexts can be highly useful in assisting them to carry out daily routines and activities. Usage patterns of different categories smartphone apps such as social networking, communication, entertainment, or daily life services related apps usually vary greatly between individuals. People use these apps differently in different contexts, such as temporal context, spatial context, individual mood and preference, work status, Internet connectivity like Wifi status, or device related status like phone profile, battery level etc. Thus, we consider individuals’ apps usage as a multi-class context-aware problem for personalized modeling and prediction. Random forest learning is one of the most popular machine learning techniques to build a multi-class prediction model. Therefore, in this paper, we present an effective context-aware smartphone apps prediction model, and name it “AppsPred” using random forest machine learning technique that takes into account optimal number of trees based on such multi-dimensional contexts to build the resultant forest. The effectiveness of this model is examined by conducting experiments on smartphone apps usage datasets collected from individual users. The experimental results show that our AppsPred significantly outperforms other popular machine learning classification approaches like ZeroR, Naive Bayes, Decision Tree, Support Vector Machines, Logistic Regression while predicting smartphone apps in various context-aware test cases.

Determinants of exercise behaviour in persons with Parkinson’s disease

Background Exercise shows promise for improving physical and cognitive functioning, quality of life, and mood in individuals with Parkinson’s disease (PD). Structured interviews have suggested potential factors influencing participation in exercise in this population, but no studies have examined if they predict exercise behaviour. Methods Thirty persons with PD completed the International Physical Activity Questionnaire and a semi-structured interview. Time spent exercising was calculated by summing responses for recreation, sport, and leisure-time physical activity. Predictors of exercise were assessed via interview. In addition, participants were asked about what types of exercise they engaged in and what types of exercise they would be interested in trying. Regression analyses were used to identify the factors that predicted time spent exercising, as well as determining factors in low vs. high exercisers (≥150 min per week). Results Positive predictors of exercise were being male (β= −0.52, p = 0.01; χ 2 = 4.84, p = 0.03), married (β = 0.32, p = 0.03; χ 2 = 5.60, p = 0.02), and enjoyment of exercise (β = 0.36, p = 0.02). Fear of falling (β = −0.41, p = 0.01; χ 2 = 4.29, p = 0.04), negative perception of health (β = −0.41, p = 0.02), perception of PD symptoms (χ 2 = 12.45, p < 0.001), bad weather (χ 2 = 5.06, p = 0.02), and lack of an exercise partner (χ 2 = 13.39, p < 0.001) were negative predictors of exercise. Conclusions Results from this study suggest that exercise programmes should work to make activities enjoyable, safe, and adaptable to the abilities of the individual. Programmes should also include social engagement. Implications for rehabilitation Parkinson’s exercise programmes should be enjoyable. Parkinson’s exercise programmes should include both social engagement and social support. Parkinson’s exercise programmes should be safe and adaptable to the abilities of the participants. Parkinson’s exercise programmes should aim to improve balance and reduce fear of falling. Individual exercise programmes can also be successful, many people with PD exercise alone with the most common form being walking.

Mood States and Everyday Creativity: Employing an Experience Sampling Method and a Day Reconstruction Method.

Investigating the mood-creativity relationship in everyday life is important for innovation promotion in organizational management. This study explores the relationship between mood states and everyday creativity using two different measurement methods. Both the experience sampling method (ESM) and the day reconstruction method (DRM) were simultaneously applied to conduct a 15-day follow-up study of the relationship between 10 typical positive and negative moods and creativity in daily situations. In total, 31 corporate employees participated in the study. Participants reported their mood states and creativity at three time points per day by using ESM; they also recalled and reported their mood states and creativity for at least three major events per day at the end of each day by using DRM. In total, we collected 935 valid measurements from ESM and 1260 valid measurements from DRM. The results revealed that highly active, positive moods including happiness, concentration, feeling active and interested had significant positive correlations with creativity, while the low-activity, negative mood states of feeling tired and sleepy were associated with low creativity. Both DRM-based and ESM-based results were largely consistent in measuring individual’s mood states and everyday creativity. To our knowledge, this is the first study to conduct DRM for mood-creativity relationship. The high consistency between the two daily research methods provides further empirical evidence toward a comprehensive understanding of mood and creativity. As DRM imposes a lessened respondent load on the participants as compared to ESM, our results suggest DRM as a promising tool for further mood-creativity research.

The Positive Impact of African Drumming on Elderly Participants’ Mood and Demeanour

This article reports on a study that examined the effects of African drumming on the mood and demeanour of older individuals, both those with and those without dementia, in Hong Kong. Previous research indicated that music-making has a positive effect on older adults’ overall health and well-being. The study participants’ mood and demeanour were measured through observer and self-rating before and after taking part in one of three African drumming sessions. There was a significant improvement in all aspects of all the participants’ mood and demeanour after participating in the drumming sessions. A positive impact of the drumming session was also found on the caregivers. The drumming sessions involved physical activity, skill acquisition, reminiscence, joint music making and social interaction that all could have led to the large positive changes in mood and demeanour found in the study participants.

The preholiday corporate announcement effect

We find that investors react more favorably to corporate announcements of share repurchases, SEOs, earnings, dividend changes, and acquisitions if the announcement is made immediately prior to or on holidays. These announcements are associated with more positive reactions for favorable events and less negative reactions for unfavorable events. This effect is robust to controls for market conditions and a selection bias, is accompanied by subsequent reversals, and is present in several international markets. Our findings suggest that predictable individual mood changes can cause biases in market reactions to firm-specific news.

경도인지장애 환자의 주관적 기억장애, 우울 및 집행기능이 일상생활 수행능력에 미치는 영향

Purpose: This study aimed to examine the effects of subjective memory complaints, depression and cognitive function on performance of activities of daily living (ADL) in individuals with mild cognitive impairment (MCI). Methods: A total sample consisted of 250 MCI patients diagnosed within one year. All participants were assessed with a battery of standardized neuropsychological tests, self-report measures of subjective memory complaints and depression, and performance of basic and instrumental ADL. Correlational and multiple linear regression analyses were conducted to identify the factors associated with performance of basic and instrumental ADL, respectively. Results: Executive function and depression explained 9.4% of the variance in basic ADL. Reduced executive function and greater depressed mood were associated with worse performance on basic ADL. Executive function, subjective memory complaints, and time since onset of cognitive symptoms accounted for 22.2% of the variance in instrumental ADL in individuals with MCI. Lower executive function (t=-2.02, p=.044), greater memory complaints (t=5.36, p.001), and longer periods of experiencing cognitive symptoms (t=2.24, p=.026) were associated with worse instrumental ADL performance. Conclusion: These results may help healthcare professionals develop interventions to improve cognitive outcomes with better understanding of the relationship among cognition, mood, and behavioral performance in individuals with MCI.

Epidemiology of Depression in Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Systemic Sclerosis

Background: Depression is a major disabling factor around the world. Most of the mental disorders immediately affect the inner mood and cognitive aspect of individuals. Therefore, hiding the depression can delay the early diagnosis and, consequently, a proper treatment in the patients. Objectives: We designed the study to determine the association between rheumatoid diseases and depression. Methods: This is a descriptive - analytic study which was performed on 354 patients referred to Rheumatology Clinic of Ahvaz, a province in south west of Iran in 2016. Then demographic information, depression, quality of life and social support were completed based on standardized questionnaires filled by the patients. Results: The prevalence of depression in rheumatoid arthritis (RA), systemic lupus erythematous (SLE) and systemic sclerosis (SSc) patients was 61.63%, 73.52% and 60%, respectively. There is a meaningful relationship between depression, age and duration of disease in SSc patients. There is a significant relationship between depression and gender in SLE and RA patients. There is a significant relationship between depression and the degree of education of SLE patients. There is a meaningful relationship between depression and quality of life, social support and corticosteroid consumption. Conclusions: The prevalence of depression is very high in all three diseases, which is equal in terms of quality of life, social support and corticosteroid usage in all three diseases. Psychiatric disorders such as depression are common in rheumatic patients.

Acute Subjective and Behavioral Effects of Microdoses of Lysergic Acid Diethylamide in Healthy Human Volunteers

BackgroundNumerous anecdotal reports suggest that repeated use of very low doses of lysergic acid diethylamide (LSD), known as microdosing, improves mood and cognitive function. These effects are consistent both with the known actions of LSD on serotonin receptors and with limited evidence that higher doses of LSD (100–200 μg) positively bias emotion processing. Yet, the effects of such subthreshold doses of LSD have not been tested in a controlled laboratory setting. As a first step, we examined the effects of single very low doses of LSD (0–26 μg) on mood and behavior in healthy volunteers under double-blind conditions. MethodsHealthy young adults (N = 20) attended 4 laboratory sessions during which they received 0 (placebo), 6.5, 13, or 26 μg of LSD in randomized order at 1-week intervals. During expected peak drug effect, they completed mood questionnaires and behavioral tasks assessing emotion processing and cognition. Cardiovascular measures and body temperature were also assessed. ResultsLSD produced dose-related subjective effects across the 3 doses (6.5, 13, and 26 μg). At the highest dose, the drug also increased ratings of vigor and slightly decreased positivity ratings of images with positive emotional content. Other mood measures, cognition, and physiological measures were unaffected. ConclusionsSingle microdoses of LSD produced orderly dose-related subjective effects in healthy volunteers. These findings indicate that a threshold dose of 13 μg of LSD might be used safely in an investigation of repeated administrations. It remains to be determined whether the drug improves mood or cognition in individuals with symptoms of depression.

PSYCHOLOGICAL RESILIENCE ON CAREER ANCHORS

 ABSTRACT Globalization and rapid evolution in technology have brought about intense competition among organizations to meet their customers’ ever-changing demands. Attitudes and behaviors that employees exhibit in a stressful competitive environment are extremely important, it influences both their own career planning and the growth of their organization. Dispensable for the enterprises, the moods of individuals determine their resilience and directly affect the efficiency, effectiveness and competitive power of the organization. This quantitative research investigated the effects of psychological resilience on the career plans of employees in organizations. Data were collected from 359 randomly selected employees of private security service providing companies and analyzed by using the Structural Equation Modeling technique. It was determined that there was a significant and positive relationship between psychological resilience and career anchors. Results revealed that employees’ family, social environment, friendship, self-confidence and future perception are very influential on their own career anchors. Keywords : psychological resilience, career anchors, private security, service sector Jel Code: M12

Mood as a Dependent Variable in Behavioral Interventions for Individuals with ASD: a Systematic Review

The current review provides an original examination of the literature involving mood as a dependent variable in behavioral interventions designed for individuals with autism spectrum disorder (ASD). Twenty-nine single-subject experimental design studies were identified through systematic searches and evaluated in relation to the following variables: (a) participant and setting characteristics, (b) experimental design, (c) approach to mood assessment, (d) intervention procedures, and (e) intervention effects on mood. The experimental rigor of the included studies was evaluated on the National Autism Center’s Scientific Merit Rating Scale (2009). Results suggest that behavioral interventions can be successfully used to improve the mood of individuals with ASD and that observable indices of mood can be operationally defined and measured among these individuals. These observable indices of mood could be more often measured in behavioral intervention research, particularly when improved quality of life (QoL) is a stated goal of intervention. Limitations of the current research base are discussed and suggestions for future studies incorporating measures of mood in ASD populations are offered.

Altered mesocorticolimbic functional connectivity in chronic low back pain patients at rest and following sad mood induction.

Depressive symptoms are common among individuals with chronic pain. Previous work suggests that chronic pain patients have difficulty regulating emotional responses, which is a risk factor for the development of major depressive disorder (MDD). Function of the mesocorticolimbic system, a neural network associated with reward processing, contributes to emotion regulation. This network's dysfunction has been described in chronic pain and MDD research and potentially underlies the relationship among emotion dysregulation, chronic pain, and MDD development. Given that mood induction paradigms have been used to measure emotion regulation, the present study examined intrinsic mesocorticolimbic functional connectivity (FC) after induced sad mood in individuals with and without chronic low back pain (cLBP). Thirty-three MDD-free individuals (17 cLBP) underwent resting-state scanning before and after sad memory-evoked mood induction. A Group [cLBP, healthy control (HC)] x Mood (Neutral, Sadness) repeated measures ANCOVA was conducted on seed-based FC data using a mesolimbic a priori region of interest. Interaction effects were identified in the orbital frontal cortex and inferior frontal gyrus [F(2,29) = 21.07, pFDR < .05. hp2= .5]. Whereas cLBP showed significantly greater FC between these two regions and the mesolimbic seed under neutral mood, FC among these regions increased in HC and decreased in cLBP under sad mood. Exploratory graph theory analyses further describe between-group differences in mesocorticolimbic network properties. Findings support previous literature describing mesocorticolimbic dysfunction in cLBP and demonstrate aberrant function in emotion regulation. Mesocorticolimbic dysfunction during emotion regulation might contribute to the development of certain depressive phenotypes in chronic pain patients.

How Does Emotion Regulation Strategy Use and Psychological Wellbeing Predict Mood in Adults With and Without Autism Spectrum Disorder? A Naturalistic Assessment.

The aim of this study was to identify emotion regulation (ER) strategies that most strongly impact momentary mood in a sample of 23 adults with and 19 without autism spectrum disorder (ASD). Participants completed cognitive and behavioural assessments, online questionnaires, and experience sampling methodology questions. In the ASD group, the use of dampening and other-blame reduced mood while savouring and emotional acceptance improved mood. The use of self-blame and avoidance negatively impacted mood only in the non-ASD group, suggesting the use of these two strategies do not reduce mood in individuals with ASD. ER and mental health interventions should capture ER strategy use and aim to decrease maladaptive strategy use and increase adaptive strategy use.

Alcohol Use Disorder and Comorbid Depression: A Randomized Controlled Trial Investigating the Effectiveness of Supportive Text Messages in Aiding Recovery.

The aim of this randomized controlled trial was to examine the impact of daily supportive text messages over a 6-month treatment period on mood and alcohol consumption in individuals with a dual diagnosis of alcohol use disorder (AUD) and depression following completion of an inpatient treatment programme. Ninety-five adult participants with AUD and comorbid depression were recruited into this randomized control trial, which took place after completing a 30-day rehabilitation programme. The intervention group (n = 47) received twice-daily supportive text messages over 6-months while control participants (n = 48) had treatment as usual for a 6-month period, with an added 6-month post-treatment follow-up for both groups. Drinking history in the previous 90 days as well as symptoms of depression, anxiety and stress were measured at baseline, 3- and 6-month treatment points and 6-month post treatment follow up. Depression scores (P = 0.02) and perceived stress scores (P < 0.01) were significantly reduced at 3-month treatment point in the intervention group relative to control participants with small to medium effect. The intervention group also showed a significantly greater reduction in units per drinking day from baseline to 6-month treatment point compared to the control group with a medium effect size (P = 0.03). There were no differences in drinking or mood measures at 6-month post treatment follow-up. Supportive text messages provide an early initial benefit in decreasing symptoms of depression and stress, with a further positive impact on alcohol consumption following a longer treatment period. Benefits did not persist six months after the intervention ended.