The object of the study is the section of monuments of science and technology of the VOOPIK. The subject is the activity of the section of monuments of science and technology for the identification, study, accounting, preservation and updating of the corresponding category of monuments. The purpose of the study is to reconstruct the history of the emergence and functioning of this structural unit in the 1960s-1980s. The territorial framework is limited to the Sverdlovsk and Chelyabinsk regions, the leading industrial regions of the Urals, on the territory of which there were a large number of monuments of science and technology, monuments of industrial heritage. The author studies the history of the formation of the section of monuments of science and technology, and also gives a description of various types of its activities on the materials of the Sverdlovsk and Chelyabinsk regions. The problem posed has not yet been the subject of special study, and has only been touched upon in the context of the study of history in general of the All-Russian Society for the Protection of Historical and Cultural Monuments and its regional branches, in particular. This determines the scientific novelty of the article. The source material is represented by archival materials, many of which are being introduced into scientific circulation for the first time, for example, unique information about the project to create a Museum of the History of Science and Technology in Chelyabinsk. The author comes to the conclusion that there were both similar directions and significant differences in the activities of these sections. This was determined by several reasons. Of great importance was the personal factor, which also influenced the effectiveness of the functioning of the section of monuments of science and technology