You have accessJournal of UrologyBenign Prostatic Hyperplasia: Surgical Therapy and New Technology (III)1 Apr 20132181 ARE HISTOLOGICAL FINDINGS OF THULIUM LASER ENUCLEATION VERSUS TRANSURETHRAL RESECTION OF THE PROSTATE COMPARABLE? Luca Carmignani, Stefano Picozzi, Stefano Casellato, Giorgio Bozzini, Carlo Marenghi, and Serena Maruccia Luca CarmignaniLuca Carmignani San Donato Milanese, Italy More articles by this author , Stefano PicozziStefano Picozzi San Donato Milanese, Italy More articles by this author , Stefano CasellatoStefano Casellato San Donato Milanese, Italy More articles by this author , Giorgio BozziniGiorgio Bozzini San Donato Milanese, Italy More articles by this author , Carlo MarenghiCarlo Marenghi San Donato Milanese, Italy More articles by this author , and Serena MarucciaSerena Maruccia San Donato Milanese, Italy More articles by this author View All Author Informationhttps://doi.org/10.1016/j.juro.2013.02.2090AboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookTwitterLinked InEmail INTRODUCTION AND OBJECTIVES We investigated if an adequate histological diagnosis can be made from tissue after Thulium laser enucleation of the prostate (ThuLEP) and whether it is comparable to transurethral prostate resection (TURP) tissue findings in patients with symptomatic benign prostatic hyperplasia. METHODS We analyzed 100 ThuLEP and 100 matched TURP tissue specimens from patients who underwent 1 of the 2 procedures between January 2009 and October 2012. Thulium Laser Enucleation of Prostate was combined with mechanical morcellation of the resected lobe. Each histological specimen was reviewed by two pathologists. Preoperative prostate ultrasound volume, total serum prostatic specific antigen and postoperative tissue weight were evaluated. Microscopic histological diagnosis was assessed by standard histological techniques and immunohistochemical evaluation. RESULTS Patients were comparable in terms of age and preoperative total serum prostate specific antigen. Incidental adenocarcinoma and high grade PIN of the prostate were diagnosed in a comparable percent of specimens in the 2 groups (4% in the ThuLEP group versus 5% in the TURP group). Tissue thermal artifacts induced by the Thulium laser are mostly due to coagulation as that of the conventional monopolar diathermy in TURP. CONCLUSIONS Tissue quality was maintained in the ThuLEP histological specimens. Tissue maintain histological characteristics and proprieties without modification for successive immunoistochemical analysis. The pathologist ability to detect incidental prostate cancer and PIN was maintained even if there is a quoted of vaporized tissue. © 2013 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 189Issue 4SApril 2013Page: e894 Advertisement Copyright & Permissions© 2013 by American Urological Association Education and Research, Inc.MetricsAuthor Information Luca Carmignani San Donato Milanese, Italy More articles by this author Stefano Picozzi San Donato Milanese, Italy More articles by this author Stefano Casellato San Donato Milanese, Italy More articles by this author Giorgio Bozzini San Donato Milanese, Italy More articles by this author Carlo Marenghi San Donato Milanese, Italy More articles by this author Serena Maruccia San Donato Milanese, Italy More articles by this author Expand All Advertisement Advertisement PDF downloadLoading ...