Renal allografts were carried out in dogs, the kidney being placed in the neck. After operation, ultrasonic and electromagnetic renal blood flow studies were carried out on alternate days. Postoperatively, an increase in blood flow was seen for the first 2–3 days, and thereafter a progressive fall in blood flow was observed until the animal died of rejection. A high degree of correlation was observed between the two methods of blood flow measurement. From these observations, it is concluded that ultrasonic methods of monitoring blood flow changes in rejection of human renal allografts is a useful adjunct in the clinical diagnosis of rejection.
Read full abstract