This paper examines the role of monetary policy in addressing economic crises by analyzing four significant events in U.S. history: Great depression, stagflation in 1970-198, the 2008 financial crisis and the COVID-19. The monetary policy in the country's economic management has been highlighted in order to resist the decline in financial activity, inflation, large-scale unemployment, and economic recession. History evaluation of policy responses and the results can be employed to assess the efficacy of monetary measures, such as quantitative easing and interest rate adjustments, in achieving financial stability and economic recovery. Nevertheless, this paper points out that it is paramount for the monetary policy adjustment to different economic conditions, and stresses that financial supervision should have the power to avoid speculative activities and guarantee the stability of financial system. The outcomes contribute to deeper knowledge of monetary policy as a tool in managing the crises and provide valuable insights for the policymakers for strategy formulation in future challenges.