Mole Of Solute Research Articles

MORPHOLOGICAL PECULIARITIES OF THE SKIN GRANULATION TISSUE IN PATIENTS WITH MALIGNANT NEOPLASMS OF THE ABDOMINAL ORGANS.

The aim: To examine morphological peculiarities of the skin granulation tissue from the laparotomy wound in patients with malignant neoplasms of the abdominal organs. Materials and methods: 36 bodies of deceased people were examined after midline laparotomy performed for surgical treatment of diseases of the abdominal organs. The main group included 22 bodies of deceased people suffering from malignant neoplasms of the abdominal organs, mostly in ІІІ-IV stages of diseases. The group of comparison included 14 bodies of deceased individuals suffering from acute surgical diseases of the abdominal organs. An average length of the laparotomy wound was 24,5 ± 0,28 cm. An average distance from the reticular elements to the external border of the granulation tissue was measured by means of computed histometry (mcm), the optical density (OD) of staining of the collagen fibers was determined by means of computed microdencitometry (expressed in OD absorbance coefficient - the absorbance of the solution per unit length per mole of solute), the specific volume of the blood vessels in the granulation tissue - by means of computed histostereometry (%), the granulation tissue cells were calculated by means of the score test (within eyeshot 10000 mcm2). The specimens were stained with hematoxylin, eosin and methylene blue/Chromotrop 2B. Results: The obtained results of the investigation conducted are indicative of more prominent chromotropic properties in the samples of the main group, confirming certain biochemical changes and features of the collagen fibers respectively. Moreover, slide mounts of the main group possess reliably lower optic density of staining of the collagen fibers which is indicative of their slow formation. It may suggest a reduced solidity of the postoperative scar on the laparotomy wound skin promoting easier wound disruption, that is, occurrence of subcutaneous eventration in patients with malignant neoplasms of the abdominal organs. Conclusions: Oncological process in the body results in the aggravation of swelling and chromotropophilia in the deep layers of derma during more remote terms after surgery and reduced optic density of the collagen fibers staining, which promotes easier laparotomy wound disruption and occurrence of true postoperative eventration.

Volumetric and transport properties of switchable-hydrophilicity solvent systems: N,N-Dimethylbutylamine, water and carbon dioxide

Switchable-hydrophilicity solvents (SHSs) are an emerging class of solvents with switchable phase behavior. They can be used as a substitute for volatile solvents and can be removed from organic products without distillation. However, the detailed physical properties data of SHSs are still very scarce in the literature. In this work, the experimental values densities, dynamic viscosities, refractive indices as well as conductivities of switchable hydrophilicity solvent (SHS)systems (N,N-Dimethylbutylamine (DMBA), water, and carbon dioxide) are investigated at temperatures (283.15, 288.15, 293.15, 298.15, 303.15 and 308.15) K and at atmospheric pressure. VLE of the CO2 loaded DMBA solutions are measured at 298.15 K over the partial pressure range of carbon dioxide from 17.0 to 98.0 kPa. Density data have been used to calculate the apparent molar volumes (Vϕ), limiting apparent molar volumes (Vϕ0) and limiting partial molar expansivity of solute (Eϕ0). The Jones-Dole coefficients B, the Gibbs free energies of activation of viscous flow per mole of solvent (Δμ10≠) and per mole of solute (Δμ20≠), entropies (ΔS20≠) and enthalpies (ΔH20≠) of activation of viscous flow were calculated from experimental viscosity data and discussed in terms of transition state theory. The Walden's product was calculated from the conductance and dynamic viscosity data. The results are valuable sources of information on the design and development of SHSs for novel industrial applications.

Probing interactions and hydration behaviour of drug sodium salicylate in aqueous solutions of D-xylose/L-arabinose: Volumetric, acoustic and viscometric approaches

The solute–solute and solute–solvent interactions of drug sodium salicylate in aqueous-carbohydrate solutions are investigated using experimentally measured densities, ρ, ultrasonic speeds, u and viscosities, η of the drug sodium salicylate in water and in aqueous−D-xylose/L-arabinose (5% and 10% D-xylose/L-arabinose in water, w/w) solvents at temperatures (293.15, 298.15, 303.15, 308.15, 313.15 and 318.15) K and at atmospheric pressure. The ρ, u and η data were used to calculate the apparent molar volumes, Vϕ, limiting apparent molar volumes, Vϕ°, limiting apparent molar expansibilities, Eϕ°, apparent molar compressibilities, Ks,ϕ, limiting apparent molar compressibilities, Ks,ϕ° along with the transfer volumes, Vϕ,tr° and transfer compressibilities, Ks,ϕ,tr°. Furthermore, Falkenhagen coefficient A, Jones-Dole coefficient B, free energy of activation of viscous flow per mole of solvent, Δμ1°# and per mole of solute, Δμ2°#, enthalpies, ΔH°# and entropies, ΔS°#of activation of viscous flow were obtained from the viscosity data. The observed trends in these properties as function of temperature and composition were analysed in terms of molecular interactions amongst the solute and solvent molecules. The results are discussed in terms of hydrophilic-hydrophilic and hydrophilic-hydrophobic interactions in these systems along with the structure breaking/making ability of the drug.

Volumetric and transport properties of ternary solutions of l-serine and l-valine in aqueous NaCl solutions in the temperature range (293.15–323.15) K

In this paper we report new density and viscosity data of l-serine and l-valine in aqueous NaCl solutions as a function of amino acids molality at fixed salt concentration (0.1, 0.2, 0.5, 0.7 and 1.0 mol·kg−1) and temperature T = (293.15, 298.15, 303.15, 308.15, 313.15, 318.15 and 323.15) K at atmospheric pressure of p = 0.1 MPa. From density, some derived properties such as the apparent molar volume, Vϕ, limiting partial molar volume, Vϕ0, and expansibility, Eϕ0, standard molar volume of transfer, ΔVϕ0, and hydration number, nH, were calculated and discussed in terms of solute–solvent interactions and structural effects. The Jones–Dole equation and transition state treatment were used to obtain the viscosity B coefficient, free energy of activation of viscous flow per mole of solvent, Δμ10#, and per mole of solute, Δμ20#, entropies, ΔS20#, and enthalpies, ΔH20#, of activation of viscous flow for amino acids. All the activation parameters were discussed in terms of transition state theory. The co-sphere overlap model was used to interpret the results. The structure making/breaking ability of the amino acids in solutions was also discussed.

Studies on Volumetric and Viscometric Properties of L-Glutamic Acid in Aqueous Solution of Glucose over a Range of Temperatures (298K to 323K)

In this work, volumetric and viscometric properties of L-glutamic acid in water and aqueous glucose solutions (5%, 10%, 15%, and 20% of glucose, w/w in water) have been measured as a function of molal concentration (0.02 mol.kg-1 to 0.16 mol.kg-1) of L-glutamic acid at different temperatures T= (293.15, 303.15, 308.15, 313.15 and 323.15) K. By using experimental densities (ρ) and viscosities (η) data, apparent molar volume (φv), experimental slope (Sv), limiting apparent molar volume (φv0), limiting apparent molar volume transfer (Δφv0)tra, limiting apparent molar expansibilities (Eφ0), Hepler’s constant (δEφ0/δT)p, Falkenhagen coefficient A, and Jones-Dole coefficient B have been computed. Gibbs free energies of activation of viscous flow per mole of solvent (μ_1^(0#)) and per mole of solute 〖(μ〗_2^(0#)), hydration number (Hn) is also calculated. The results are discussed based on solute-solute and solute-solvent interactions in these systems. From the results, it is observed that there exists a structure making propensity of L-glutamic acid in water and in the different mass fraction of aqueous glucose solutions, which increases with the increase of glucose concentrations.

Molecular Interactions of Non-Steroid Anti-Inflammatory Drug Dolonex in Aqueous Solutions of L-Alanine/L-Valine at Different Temperatures: Viscometric Approach

The viscosities of aqueous solutions of L-alanine and L-valine with non-steroid anti-inflammatory drug dolonex (0.020, 0.040, 0.060 mol kg–1) have been measured at different temperatures (293.15–313.15 K) and at atmospheric pressure. On the basis of experimental results Jones–Dole coefficient-B, viscosity B-coefficient of transfer, activation parameters i.e., free energy of activation of viscous flow per mole of solvent $$\Delta \mu _{2}^{{^\circ \# }}$$ and per mole of solute $$\Delta \mu _{1}^{{^\circ \# }}$$ were determined. The obtained results were discussed in terms of solute–solvent interactions in these solutions. Moreover, structure breaker tendency of solute molecules were obtained by measuring temperature derivative of viscosity B-coefficient.

Viscometric and spectroscopic studies on interactions of glycine with aqueous buffer solutions

Abstract To study the solvation and hydration behavior of glycine, viscosity measurements have been carried out for glycine in water of pH = (1.00, 7.40 and 14.00) and in different concentrations (0.1, 0.5 and 1.0) M of aqueous potassium/sodium phosphate buffer (KPB/NaPB) solutions of pH = (1.00, 7.40 and 14.00) at different temperatures, T = (298.15, 308.15, 310.15 and 318.15) K. Viscosity B-coefficients for glycine in water and in aqueous buffer solutions have been obtained at different temperatures using Jones-Dole equation. Viscosity B-coefficients of transfer (∆trB) values have been calculated from viscosity B-coefficient data. Both positive and negative viscosity B-coefficients of transfer have been observed in the studied system. The Gibbs energies of activation for viscous flow per mole of solvent (∆μ1o) and per mole of solute (∆μ2o) have been calculated and discussed in terms of transition state theory. Solvation (Sn) and hydration (nH) numbers have also been calculated from these data. The results have been discussed in terms of solute-solvent and solute-solute interactions in these systems. The structure-making/breaking ability of glycine has been discussed in terms of the sign of dB/dT. UV absorption spectra for glycine in aqueous KPB solutions has been recorded. All the viscometric and spectroscopic parameters have been used to explore various interactions that may arise in presently investigated ternary solutions.

Study on the interactions of drug isoniazid in aqueous-D-xylose/L-arabinose solutions at different temperatures using volumetric, acoustic and viscometric approaches

Volumetric, acoustic and viscometric properties of drug isoniazid in water and aqueous solutions of carbohydrates, D-xylose and L-arabinose (5% and 10% D-xylose/L-arabinose in water, w/w) were studied at various temperatures, T = (293.15–318.15) K and at atmospheric temperature. The apparent molar volumes, Vϕ and apparent molar compressibilities, Ks,ϕ were calculated from the experimentally measured densities and ultrasonic speeds. Limiting apparent molar volumes, Vϕ°, limiting apparent molar compressibilities, Ks,ϕ°, limiting molar expansibilities, Eϕ° and their corresponding transfer volumes, Vϕ,tr° and transfer compressibilities, Ks,ϕ,tr° of drug isoniazid from water to aqueous carbohydrate solutions were also evaluated. Falkenhagen Coefficients, A, Jones-Dole coefficients, B, variation of B with temperature, dB/dT, free energies of activation of viscous flow per mole of solvent, Δμ1°# and per mole of solute, Δμ2°#, enthalpies, ΔH°# and entropies, ΔS°# of activation of viscous flow were calculated from the viscosity measurements. The negative sign of dB/dT indicated the structure making ability of the drug isoniazid. The results obtained have been discussed in terms of solute-solvent interactions in order to understand the solvation behaviour of isoniazid in these aqueous-carbohydrate solutions.

Solute-solute and solute-solvent interactions of drug sodium salicylate in aqueous-glucose/sucrose solutions at temperatures from 293.15 to 318.15 K: A physicochemical study

Physical properties like ultrasonic speed and compressibility give us an idea about the type of interactions prevailing in the solutions. Keeping this in view, we have measured the densities, ρ, ultrasonic speeds, u and viscosities, η of the drug sodium salicylate in water and in aqueous−D-glucose/d-sucrose (5 wt% and 10 wt% glucose/sucrose in water) solvents at different temperatures (293.15, 298.15, 303.15, 308.15, 313.15 and 318.15) K and at atmospheric pressure. These experimental values have been used to calculate apparent molar volumes, Vϕ and apparent molar compressibilities, Ks,ϕ, limiting apparent molar volumes, Vϕ° and limiting apparent molar compressibilities, Ks,ϕ°. The transfer volumes, Vϕ,tr° and transfer compressibilities, Ks,ϕ,tr° of sodium salicylate from water to aqueous carbohydrate solutions were also calculated. The co-sphere model has been used to interpret the transfer molar properties. Using the η data, the viscosity A and B coefficients have been calculated. The variation of viscosity B coefficient with respect to temperature, i.e., dB/dT have been investigated, the sign of which is indicative of the structure making/breaking ability of the drug in these media. The free energy of activation of viscous flow per mole of solvent, Δμ1°# and per mole of solute, Δμ2°#, enthalpies, ΔHο# and entropy, ΔSο# of activation of viscous flow, were also obtained from the viscosity data. The results obtained are discussed in terms of solute-solute and solute-solvent interactions prevailing in these solutions.

Molecular interactions of gentamicin sulphate in aqueous-l-asparagine/l-glutamine solutions at different temperatures: Volumetric, acoustic and viscometric properties

The solute-solute and solute-solvent interactions are investigated by using the experimental values densities, ρ, ultrasonic speeds, u and viscosities, η of gentamicin sulphate in water and in aqueous l-asparagine/l-glutamine (1% and 2% l-asparagine/l-glutamine in water) solvents at temperatures (293.15, 298.15, 303.15, 308.15, 313.15 and 318.15) K and at atmospheric pressure. The experimental ρ and u data have been used to calculate the apparent molar volumes, Vφ, limiting apparent molar volumes, Vϕ°, apparent molar compressibilities, Ks, ϕ, limiting apparent molar compressibilities, Ks, ϕ°, transfer volumes, Vϕ, tr°, transfer compressibilities, Ks, ϕ, tr° and limiting partial molar expansivity of solute, Eϕ°. Also, the Falkenhagen Coefficients, A and Jones-Dole coefficients, B were evaluated from experimental viscosity data. The Gibbs free energies of activation of viscous flow per mole of solvent, Δμ1°# and per mole of solute, Δμ2°#, entropies, ΔSο and enthalpies, ΔHο of activation of viscous flow were also calculated and discussed in terms of transition state theory. These parameters have been discussed in connection with the electrostatic interactions between the zwitterionic groups of amino acids and drug molecules. The structure-making/breaking ability of the drug in these solutions was also analyzed using the signs and magnitudes of (∂2Vϕ°/∂T2) and dB/dT coefficients.

Volumetric, acoustic and viscometric studies of solute-solute and solute-solvent interactions of isoniazid in aqueous-glucose/sucrose solutions at temperatures from 293.15 K to 318.15 K

The densities, ρ, ultrasonic speeds, u and viscosities, η of the drug isoniazid in water and in aqueous–d-glucose/d-sucrose (5 wt% and 10 wt% glucose/sucrose in water) solvents were measured at temperatures (293.15, 298.15, 303.15, 308.15, 313.15 and 318.15) K and at atmospheric pressure. The ρ, u and η data have been used to calculate apparent molar volumes, Vϕ, limiting apparent molar volumes, Vϕ∘, apparent molar compressibilities, Ks,ϕ, limiting apparent molar compressibilities, Ks,ϕ∘, transfer volumes, Vϕ,tr∘ and transfer compressibilities, Ks,ϕ,tr∘. The viscosity data have been used to determine Falkenhagen Coefficients, A and Jones-Dole coefficients, B. The calculated parameters have been discussed in terms of various solute-solute and solute-solvent interactions prevailing in these solutions. The structure making/breaking ability of isoniazid in these solutions has been examined by using the sign of dB/dT. Furthermore, the Gibbs energies of activation of viscous flow per mole of solvent, Δμ1∘# and per mole of solute, Δμ2∘#, enthalpies, ΔH∘ and entropies, ΔSo of activation of viscous flow, were also calculated and discussed in terms of transition state theory.

Physicochemical study of solute-solute and solute-solvent interactions of homologous series of α-amino acids in aqueous-isoniazid solutions at temperatures from 293.15 to 318.15 K

Drug-amino acid interactions have been investigated in aqueous media from the experimentally measured data of densities, ρ, ultrasonic speeds, u and viscosities, η of glycine, l-alanine, l-valine and l-isoleucine in water and in aqueous-isoniazid (1% and 2% isoniazid in water, w/w) solvents at temperatures (293.15, 298.15, 303.15, 308.15, 313.15 and 318.15) K and at atmospheric pressure. The ρ and u data have been used to calculate the apparent molar volume, Vφ, limiting apparent molar volume, Vϕ°, apparent molar compressibility, Ks,ϕ, limiting apparent molar compressibility, Ks,ϕ°, transfer volume, Vϕ,tr°, and transfer compressibility, Ks,ϕ,tr° and hydration number, nH. The viscosity data have been used to determine Falkenhagen Coefficient, A, Jones-Dole coefficient, B, free energy of activation of viscous flow per mole of solvent, Δμ1°# and per mole of solute, Δμ2°#. These parameters have been discussed in terms of solute-solute and solute-solvent interactions prevailing in these solutions. A detailed insight into the structure making/breaking ability of the amino acids in these solutions has been retrieved through the close perusal of all these parameters. In addition, the values of Vϕ°, Ks, ϕ°, B and Δμ2°# have been split into groups' contributions of the amino acids. Entropies, ΔS°# and enthalpies, ΔH°#of activation of viscous flow for amino acids in aqueous isoniazid solutions have been used to interpret interactions between the ions of amino acids and isoniazid.

Molecular Interactions in L-threonine Aqueous-Lactose Solutions at (293.15–313.15) K on Viscometric Data

Viscosity measurements of L-threonine in the range (0.025–0.2) mol kg–1 in various aqueous-lactose solutions (0–6 wt % of lactose in water) have been carried out at temperatures (293.15–313.15) K. Jones–Dole coefficients, viscosity B-coefficients of transfer, Btr, variation of B with temperature, dB/dT and solvation behavior, B/ $$V_{\phi }^{^\circ }$$ of L-threonine have been obtained. Further, the free energy of activation of viscous flow per mole of solvent, as well as per mole of solute, along with activation enthalpy, and activation entropy has also been evaluated. The results have been interpreted in terms of various molecular interactions prevalent in these systems and moreover, it has been seen that the L-threonine acts as structure maker in all studied solutions.

Viscometric, thermodynamic and theoretical DFT studies of dl-2-aminobutyric acid in aqueous sodium nitrate solutions at different temperatures

The dynamic viscosities of six pseudobinary systems consisting of dl-2-aminobutyric acid + pseudo-unary solvent (aqueous sodium nitrate solutions) were determined, in the temperature range of 283.15–318.15 K, each 5 K under pressure of 101.1 kPa, using a microviscometer automatic Anton Paar (AMVn). Absolute viscosities, relative viscosities, solvation numbers, viscosity coefficients A and B, the slope (dB/dT), activation free energy per mole of solute, the enthalpy of partial molar activation, and zwitterionic partial molar activation entropy were calculated at infinitesimal concentration. Also, the intermolecular structures and interactions of several water-sodium nitrate-dl-2-aminobutyric acid molecular complexes were theoretically modeled from DFT electronic calculations by using the B3LYP/6-31G(d) chemical model. It was found that the forces between zwitterion-pseudo-unary solvent species dominate the viscosimetric behavior of the six systems studied at all concentrations and temperatures. We also analyzed the activation parameters of the viscous flow with respect to the solute, and it was found that the zwitterion is more ordered in the transition state at the expense of a process of viscous endothermic flow and by predominance of zwitterion-solvent interactions.

Study of viscometric properties of L-ascorbic acid in binary aqueous mixtures of D-glucose and D-fructose

ABSTRACTThe relative viscosities and activation parameters of L-ascorbic acid have been determined in water and binary aqueous mixtures of D-glucose and D-fructose at different temperatures. A and B-coefficients of Jones–Dole equation are determined using density and viscosity data. Gibbs energy of activation of viscous flow per mole of solvent as well as per mole of solute along with activation enthalpy and entropy is also determined using Feakin’s transition-state theory. The obtained results are explained in terms of intermolecular interactions and in this study L-ascorbic acid has been found as structure breaker in binary aqueous mixtures of D-glucose and D-fructose.

Study of solute-solute and solute-solvent interactions of streptomycin sulphate in aqueous-l-asparagine/l-glutamine solutions at different temperatures by using physicochemical methods

The densities, ρ of streptomycin sulphate in water and in aqueous l-asparagine/l-glutamine (1% and 2% l-asparagine/l-glutamine in water, w/w) solvents were measured at temperatures (293.15, 298.15, 303.15, 308.15, 313.15 and 318.15) K; and ultrasonic speeds, u and viscosities, η of these solutions were measured at temperatures (298.15, 303.15, 308.15, 313.15 and 318.15) K and at atmospheric pressure. The ρ, u and η data have been used to calculate apparent molar volumes, Vϕ, limiting apparent molar volumes, Vϕ°, apparent molar compressibilities, Ks,ϕ, limiting apparent molar compressibilities, Ks,ϕ°, transfer volumes, Vϕ,tr°, transfer compressibilities, Ks,ϕ,tr° and limiting partial molar expansibilities, Eϕ°. The viscosity data have been used to determine Falkenhagen Coefficients, A and Jones-Dole coefficients, B. These parameters have been discussed in terms of solute-solute and solute-solvent interactions prevailing in these solutions. The structure making/breaking ability of streptomycin sulphate in these solutions is also discussed. Furthermore, the Gibbs free energies of activation of viscous flow per mole of solvent, Δμ1°# and per mole of solute, Δμ2°#, entropies, ΔSο and enthalpies, ΔHο of activation of viscous flow were also calculated and discussed in terms of transition state theory.

Hydration and Solvation Effect of Glycine and Glycylglycine Molecules with β-Cyclodextrin in Aqueous Media. A Thermodynamic Characteristic of Interaction

Abstract The densities, ρ and viscosities, η have been measured for DL- glycine (Gly) and glycylglycine (Gly-Gly) in aqueous β cyclodextrin, (β-CD) at temperature 298.15, 303.15, 308.15, 313.15 and 318.15 K. Interaction between macrocyclic β-CD and amino acids was studied by two independent technique: density and viscosity. The two different intensive properties are used to obtain various thermodynamic characteristics of the material behavior. Using the measured density data the apparent molar volumes, Vϕ , partial molar volume at infinite dilution, V ϕ ο , $V_\phi ^o,$ experimental slope, SV , isobaric expansibility, ϕ E 0 , $\phi _E^0,$ and the partial molar volume of transfer at infinite dilution, Δ V ϕ ( t r ) ο $\Delta V_{\phi (tr)}^o$ have been obtained. Moreover, the Falkenhagen’s theoretical coefficient, A, Jones-Dole coefficient, B, free energies of activation of viscous flow per mole of solvent, Δ μ 1 ο # $\Delta \mu _1^{o\# }$ and per mole of solute, Δ μ 2 ο # , $\Delta \mu _2^{o\# },$ enthalpy, ΔHo # and entropy, ΔSo # of activation of viscous flow have been evaluated by using viscosity data. The negative value of transfer volume for Gly and Gly-Gly in aqueous β-CD suggests that the hydrophobic-hydrophilic and hydrophobic-hydrophobic interactions are predominating over ionic-hydrophilic and hydrophilic-hydrophilic interactions. The results indicate the formation of a stable complexation between the β-CD cavity and structural hydration effect of amino acids on the thermodynamic of their interactions in solutions.

Volumetric, Compressibility, Taste Behavior and Viscometric Studies of Methionine with Some Saccharides in Aqueous Medium at Different Temperatures

The density, speed of sound and viscosity of methionine (0.025–0.200 mol·kg−1) in water and some aqueous saccharides (0.1 mol·dm−3 glucose, 0.1 mol·dm−3 sucrose and 0.1 mol·dm−3 lactose) have been measured at temperatures of (293.15, 298.15, 303.15, 308.15 and 313.15) K. Using the experimental values of density and speed of sound, apparent molar volume, limiting apparent molar volume, transfer volume, as well as apparent molar isentropic compressibility, limiting apparent molar isentropic compressibility, transfer compressibility, partial molar expansibility, coefficient of thermal expansion, hydration number and taste behavior have been obtained. Jones–Dole coefficient, viscosity B-coefficients of transfer and variation of B with temperature have also been obtained from viscosity data. The Gibbs energy of activation of viscous flow per mole of solvent as well as per mole of solute, along with other activation parameters, were evaluated employing Feakin’s transition state theory.

Volumetric and viscometric properties of amino acids in aqueous maltitol solutions at T = (293.15–323.15) K

The densities and viscosities of the ternary mixtures of glycine, l-alanine, l-valine, l-threonine and l-arginine in aqueous maltitol solutions were measured at T=(293.15–323.15)K under the atmospheric pressure. The apparent molar volume (Vφ), the limiting partial molar volume (Vφ0) and the limiting partial molar volume of transfer (ΔtrVφ0) were obtained in terms of the measured density, then the viscosity B-coefficient was further calculated by the least-square method. Meanwhile, the partial molar isobaric expansion (E20), the isobaric thermal expansion coefficient (α2), the solvation number (nS), the free energies of activation per mole of solvent (Δμ10≠) and per mole of solute (Δμ20≠) were also calculated. The volumetric and viscometric properties were analyzed and discussed according to the interactions between amino acids and maltitol molecules based on the co-sphere overlap model and the transition state theory.

Volumetric and viscometric study of thiamine hydrochloride, pyridoxine hydrochloride and sodium ascorbate at T = (275.15, 277.15 and 279.15) K in dilute aqueous solutions

This paper presents data for density (ρ) and relative viscosity (ηr) measurements of aqueous solutions of thiamine hydrochloride, pyridoxine hydrochloride and sodium-L-ascorbate in dilute solutions (0–0.1) mol·kg−1 at three different temperatures, T=(275.15, 277.15 and 279.15)K and at 101.3kPa. Density results have been used to calculate apparent molar volume of solute (Vϕ), limiting apparent molar volume of solute (Vϕ0), limiting apparent molar expansivity of solute (Eϕ0), (∂2Vϕ0/∂T2) and coefficient of thermal expansion (α∗). Calculated viscosity values have been correlated according to Jones-Dole equation to obtain Falkenhagen coefficient A, Jones-Dole viscosity B-coefficient, temperature derivative of B-coefficient i.e.(dB/dT) and hydration number (nH). Free energy of activation for viscous flow per mole of solvent (Δμ10#), per mole of solute (Δμ20#), entropy of activation per mole of viscous flow of solution (TΔS20#) and enthalpy of activation (ΔH20#) have also been computed through B-coefficient. These significant parameters have been discussed in terms of different molecular interactions.