This work reports solubility data of methane and carbon dioxide in 1,4 butylene glycol and the Henry's law constant of each solute in the studied solvent at saturation pressure. The measurements were performed at 303, 323, 373, 398 and 423.15 K and pressures up to 3.8 MPa for mixtures containing carbon dioxide and pressures up to 10.9 MPa for mixtures containing methane. The experiments were performed in an autoclave type phase equilibrium apparatus using a technique based on the total pressure method (synthetic method). All investigated systems show an increase of gas solubility with the increase of pressure. A decrease of carbon dioxide solubility with the increase of temperature and an increase of methane solubility with the increase of temperature were observed. From the variation of solubility with temperature, the partial molar enthalpy and entropy change of each mixture were calculated.