THIS issue contains extended versions of three of the bestrated application papers taken from the IEEE Visualization 2004 Conference. Application papers present the contribution of visualization techniques toward the understanding of application-specific data. In particular, application papers must explain the effectiveness of the visualization methods for the particular application domain. For the IEEE Visualization 2004 Conference, 24 out of 71 submitted applications papers were chosen for inclusion in the conference program. As paper cochairs of the IEEE Visualization applications track, we started from the opinion of the reviewers. From the 24 accepted papers, we have chosen three very high quality submissions and asked the authors to provide extended and revised versions of their original work for this issue. Each of the extended application papers was thoroughly reviewed by several experts and underwent revisions before it was recommended for acceptance. We are grateful to the reviewers for their detailed and timely reviews and to David Ebert, Editor-in-Chief of TVCG, for his strong support and assistance. The paper “Reconstruction and Visualization of Planetary Nebulae” by Marcus Magnor, Gordon Kindlmann, Charles Hansen, and Neb Duric exploits strong symmetry characteristics of planetary nebulae to recover spatial structures from 2D images. With GPU-based volume rendering and nonlinear optimization, the nebula’s emission density is recovered. Fascinating 3D visualizations of planetary nebulae are created, which further educational purposes and can support astrophysicists in better understanding the formation process of these phenomena. The paper “Advanced Virtual Endoscopic Pituitary Surgery” by Andre Neubauer, Stefan Wolfsberger, MarieTherese Forster, Lukas Mroz, Rainer Wegenkittl, and Katja Buhler investigates a minimally invasive endoscopic procedure for tumor removal. STEPS, a virtual endoscopy system, is presented to train surgeons on the transsphenoidal approach and assist experienced surgeons in planning a real endoscopic intervention. Interactive visualization is achieved through first-hit ray casting. The application provides various navigation and perception aids in the simulation of the surgical procedure. The paper “Visualization of Geologic Stress Perturbations Using Mohr Diagrams” by Patricia Crossno, David H. Rogers, Rebecca M. Brannon, David Coblentz, and Joanne T. Fredrich presents an inspection tool for finite element analyses of 3D real-valued second-order tensors. The Mohr diagram is a paper and pencil method from the material mechanics community. The authors originate the adaptation of this diagram type to visualize perturbed in-situ stress fields of geologic features. The Mohr diagram is used as an interactive glyph for probing as well as filtering through brushing and linking of principal stresses. Scientific visualization research is largely application driven. Many techniques are strongly motivated by the application scenario for which they were developed. Visualization research cannot be a goal by itself. It just acts as an interface tool to the domain expert to facilitate his understanding of his data and problems. Applications are therefore crucial in providing fruitful incitation for the further research of the visualization experts. The papers presented here are prime examples of how visualization helps to understand intricate application phenomena. We hope that the readers will find the papers inspiring and stimulating samples of work from our fascinating field.